IL157456A0 - Aryl and biaryl compounds having mch modulatory activity - Google Patents

Aryl and biaryl compounds having mch modulatory activity

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Publication number
IL157456A0
IL157456A0 IL15745602A IL15745602A IL157456A0 IL 157456 A0 IL157456 A0 IL 157456A0 IL 15745602 A IL15745602 A IL 15745602A IL 15745602 A IL15745602 A IL 15745602A IL 157456 A0 IL157456 A0 IL 157456A0
Authority
IL
Israel
Prior art keywords
aryl
modulatory activity
biaryl compounds
mch
mch modulatory
Prior art date
Application number
IL15745602A
Other languages
English (en)
Original Assignee
Pharmacopeia Inc Pharmacopeia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacopeia Inc Pharmacopeia filed Critical Pharmacopeia Inc Pharmacopeia
Publication of IL157456A0 publication Critical patent/IL157456A0/xx

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    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
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    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
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    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
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CN100537527C (zh) 2009-09-09
EP1370520A1 (en) 2003-12-17
CA2441235A1 (en) 2002-10-03
KR20030093257A (ko) 2003-12-06
ZA200306727B (en) 2004-11-29
AU2002247367B2 (en) 2005-10-27
HUP0400252A3 (en) 2011-09-28
JP4557492B2 (ja) 2010-10-06
JP2004526736A (ja) 2004-09-02
MXPA03008484A (es) 2003-12-08
NZ527680A (en) 2005-07-29
CA2441235C (en) 2011-05-24
JP2010001316A (ja) 2010-01-07
WO2002076929A1 (en) 2002-10-03
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US7034056B2 (en) 2006-04-25
HUP0400252A2 (hu) 2004-08-30

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