IL157359A0 - A radiopharmaceutical composition containing an ascorbic acid analog - Google Patents

A radiopharmaceutical composition containing an ascorbic acid analog

Info

Publication number
IL157359A0
IL157359A0 IL15735902A IL15735902A IL157359A0 IL 157359 A0 IL157359 A0 IL 157359A0 IL 15735902 A IL15735902 A IL 15735902A IL 15735902 A IL15735902 A IL 15735902A IL 157359 A0 IL157359 A0 IL 157359A0
Authority
IL
Israel
Prior art keywords
composition containing
ascorbic acid
acid analog
radiopharmaceutical composition
radiopharmaceutical
Prior art date
Application number
IL15735902A
Other languages
English (en)
Original Assignee
Bristol Myers Squibb Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Pharma Co filed Critical Bristol Myers Squibb Pharma Co
Publication of IL157359A0 publication Critical patent/IL157359A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0491Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0482Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group chelates from cyclic ligands, e.g. DOTA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/121Solutions, i.e. homogeneous liquid formulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15735902A 2001-02-26 2002-02-22 A radiopharmaceutical composition containing an ascorbic acid analog IL157359A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27138901P 2001-02-26 2001-02-26
PCT/US2002/005155 WO2002067859A2 (en) 2001-02-26 2002-02-22 Ascorbic acid analogs for metalloradiopharmaceuticals

Publications (1)

Publication Number Publication Date
IL157359A0 true IL157359A0 (en) 2004-02-19

Family

ID=23035343

Family Applications (1)

Application Number Title Priority Date Filing Date
IL15735902A IL157359A0 (en) 2001-02-26 2002-02-22 A radiopharmaceutical composition containing an ascorbic acid analog

Country Status (12)

Country Link
US (1) US6713042B2 (de)
EP (1) EP1365813A4 (de)
JP (1) JP2004529884A (de)
CN (1) CN1503680A (de)
AU (1) AU2002253999A1 (de)
BR (1) BR0207315A (de)
CA (1) CA2438204A1 (de)
CZ (1) CZ20032597A3 (de)
HU (1) HUP0304083A2 (de)
IL (1) IL157359A0 (de)
MX (1) MXPA03007595A (de)
WO (1) WO2002067859A2 (de)

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DE10305463A1 (de) * 2003-02-04 2004-08-12 Schering Ag Enantiomerenreines (4S,8S)- und (4R,8R)-4-p-Nitrobenzyl-8-methyl-3,6,9-triza-3N,6N,9N-tricarboxymethyl-1,11-undecandisäure und deren Abkömmlinge, Verfahren zu deren Herstellung und Verwendung zur Herstellung pharmazeutischer Mittel
US20050089470A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled peptides for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
US20050089471A1 (en) * 2003-10-24 2005-04-28 Johnson Bruce F. Labeled ligands for lectin-like oxidized low-density lipoprotein receptor (LOX-1)
WO2006020779A2 (en) * 2004-08-10 2006-02-23 Dow Global Technologies Inc. Targeting chelants and chelates
GB0427392D0 (en) * 2004-12-15 2005-01-19 Amersham Plc Stabilised 99mTc compositions
TW200803903A (en) * 2006-04-28 2008-01-16 Nihon Mediphysics Co Ltd Novel compound having affinity to amyloid
TW200808795A (en) * 2006-05-19 2008-02-16 Nihon Mediphysics Co Ltd Novel compound having affinity for amyloid
WO2007148088A2 (en) * 2006-06-21 2007-12-27 Ge Healthcare Limited Radiopharmaceutical products
EP2042501B1 (de) * 2006-06-21 2017-04-12 Nihon Medi-Physics Co., Ltd. Verbindung mit affinität zu amyloid
WO2008056481A1 (fr) * 2006-11-09 2008-05-15 Nihon Medi-Physics Co., Ltd. Agent d'imagerie de diagnostic radioactif
CN101535309A (zh) * 2006-11-17 2009-09-16 日本医事物理股份有限公司 对淀粉状蛋白具有亲和性的新化合物
NZ577511A (en) * 2006-11-30 2012-04-27 Nihon Mediphysics Co Ltd 2-Phenyl-imidazo[1,2-a]pyridine derivatives substituted with a radioactive halogen substituent
WO2008075522A1 (ja) * 2006-12-21 2008-06-26 Nihon Medi-Physics Co., Ltd. 放射性画像診断剤
TWI406674B (zh) 2007-02-13 2013-09-01 Nihon Mediphysics Co Ltd Method for manufacturing diagnostic radiographic diagnostic agents
GB0718386D0 (en) * 2007-09-21 2007-10-31 Ge Healthcare As Improved radiopharmaceutical formulation
CN101903381A (zh) * 2007-10-24 2010-12-01 日本医事物理股份有限公司 对淀粉样蛋白具有亲和性的新化合物
EP2218463A1 (de) * 2007-10-30 2010-08-18 Nihon Medi-Physics Co., Ltd. Verwendung einer neuen verbindung mit affinität für amyloid und herstellungsverfahren dafür
KR20100101576A (ko) * 2007-10-30 2010-09-17 니혼 메디피직스 가부시키가이샤 신규 아밀로이드 친화성 화합물의 사용 및 제조 방법
CA2706111C (en) * 2007-12-04 2013-06-18 Bracco Imaging S.P.A. Homogenization of a radiopharmaceutical using sonification and/or rotor-stator technology to produce a homogenous suspension, emulsion, mixture or solid suspension of immiscible ingredients
EP2328411A1 (de) * 2008-09-05 2011-06-08 Molecular Insight Pharmaceuticals, Inc. Pharmazeutische zusammensetzung aus einem radioiodiertem benzamidderivat und herstellungsverfahren dafür
FR2942227B1 (fr) * 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
CN102458396B (zh) * 2009-04-15 2017-05-10 兰休斯医疗成像公司 使用抗坏血酸稳定化放射性药物组合物
US9321095B2 (en) 2010-06-30 2016-04-26 General Electric Company Apparatuses and methods for cutting porous substrates
WO2013093099A1 (en) * 2011-12-22 2013-06-27 Piramal Imaging Sa Stabilization of peptidic radiopharmaceuticals using uric acid or derivatives thereof
WO2013176522A1 (ko) * 2012-05-24 2013-11-28 서강대학교산학협력단 카트리지를 이용한 방사성의약품 제조방법
US20140147381A1 (en) * 2012-11-29 2014-05-29 Gregory David Espenan 89zr compounds, to include somatostatin, apparatus and products comprising such compounds, methods of making same, and methods of using same for radio imaging and/or treatment
WO2014126902A1 (en) * 2013-02-15 2014-08-21 Thomas Jefferson University Kit for tumor imaging
EP3225620B1 (de) * 2014-11-27 2019-11-20 Celltrion Inc. Stabiles peptidkonjugiertes ascorbinsäurederivat, verfahren zur herstellung davon und kosmetische zubereitung damit
TWI604853B (zh) * 2016-05-03 2017-11-11 行政院原子能委員會核能研究所 放射免疫複合體、診療劑及套組
CN107167540B (zh) * 2017-07-08 2019-07-30 万舒(北京)医药科技有限公司 测定人尿液生物样品中的DTPA-Zn的方法

Family Cites Families (11)

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HU167378B (de) * 1972-05-08 1975-09-27
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
US4707353A (en) * 1982-12-08 1987-11-17 Mallinckrodt, Inc. Radiographic imaging agents
US5985240A (en) * 1989-08-09 1999-11-16 Rhomed Incorporated Peptide radiopharmaceutical applications
DK0422712T3 (da) * 1989-10-09 1994-06-27 Unilever Plc Fremgangsmåde til fremstilling af spiselige smøreprodukter og apparatur til udøvelse af fremgangsmåden
JP3853354B2 (ja) * 1991-08-29 2006-12-06 マリンクロッド・インコーポレイテッド 放射性標識ペプチドおよびタンパク質の自己放射線分解を防止する安定剤
GB9417873D0 (en) 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
AU2526497A (en) * 1996-02-02 1997-08-22 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
US6066309A (en) 1996-02-02 2000-05-23 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
US20020122768A1 (en) * 2000-07-06 2002-09-05 Shuang Liu Stable radiopharmaceutical compositions and methods for preparation thereof

Also Published As

Publication number Publication date
US20020122769A1 (en) 2002-09-05
JP2004529884A (ja) 2004-09-30
EP1365813A4 (de) 2006-03-22
CZ20032597A3 (cs) 2004-12-15
WO2002067859A2 (en) 2002-09-06
MXPA03007595A (es) 2003-12-04
CN1503680A (zh) 2004-06-09
US6713042B2 (en) 2004-03-30
AU2002253999A1 (en) 2002-09-12
HUP0304083A2 (hu) 2004-03-29
WO2002067859A3 (en) 2002-11-28
CA2438204A1 (en) 2002-09-06
EP1365813A2 (de) 2003-12-03
BR0207315A (pt) 2004-02-10

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