IL156232A0 - Method of determining a chemotherapeutic regimen based on ercc1 and ts expression - Google Patents

Method of determining a chemotherapeutic regimen based on ercc1 and ts expression

Info

Publication number
IL156232A0
IL156232A0 IL15623201A IL15623201A IL156232A0 IL 156232 A0 IL156232 A0 IL 156232A0 IL 15623201 A IL15623201 A IL 15623201A IL 15623201 A IL15623201 A IL 15623201A IL 156232 A0 IL156232 A0 IL 156232A0
Authority
IL
Israel
Prior art keywords
ercc1
expression
determining
regimen based
chemotherapeutic regimen
Prior art date
Application number
IL15623201A
Other languages
English (en)
Original Assignee
Response Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Response Genetics Inc filed Critical Response Genetics Inc
Publication of IL156232A0 publication Critical patent/IL156232A0/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL15623201A 2000-12-01 2001-11-09 Method of determining a chemotherapeutic regimen based on ercc1 and ts expression IL156232A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25035800P 2000-12-01 2000-12-01
US25047100P 2000-12-04 2000-12-04
US09/877,178 US7049059B2 (en) 2000-12-01 2001-06-11 Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression
PCT/US2001/043039 WO2002057489A2 (en) 2000-12-01 2001-11-09 Method of determining a chemotherapeutic regimen based on ercc1 and ts expression

Publications (1)

Publication Number Publication Date
IL156232A0 true IL156232A0 (en) 2004-01-04

Family

ID=27400311

Family Applications (2)

Application Number Title Priority Date Filing Date
IL15623201A IL156232A0 (en) 2000-12-01 2001-11-09 Method of determining a chemotherapeutic regimen based on ercc1 and ts expression
IL156232A IL156232A (he) 2000-12-01 2003-06-01 שיטה לקביעת משטר כמותרפויטי המבוססתעל ביטוי של ercc1 ו–ts

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL156232A IL156232A (he) 2000-12-01 2003-06-01 שיטה לקביעת משטר כמותרפויטי המבוססתעל ביטוי של ercc1 ו–ts

Country Status (14)

Country Link
US (4) US7049059B2 (he)
EP (1) EP1381691B1 (he)
JP (2) JP2004535771A (he)
KR (1) KR20030081339A (he)
CN (1) CN1596314B (he)
AR (1) AR031442A1 (he)
AU (1) AU2002246504B2 (he)
CA (1) CA2437038C (he)
ES (1) ES2422302T3 (he)
IL (2) IL156232A0 (he)
MX (1) MXPA03004928A (he)
NZ (1) NZ526711A (he)
TW (2) TWI317759B (he)
WO (1) WO2002057489A2 (he)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2390051A1 (en) * 1999-11-15 2001-05-25 University Of Southern California Thymidylate synthase polymorphism for predicting chemotherapeutic response
US20020142328A1 (en) * 2000-12-01 2002-10-03 Danenberg Kathleen D. Method of determining a chemotherapeutic regimen by assaying gene expression in primary tumors
US6602670B2 (en) * 2000-12-01 2003-08-05 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 expression
US7049059B2 (en) * 2000-12-01 2006-05-23 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression
US7662553B2 (en) * 2002-07-31 2010-02-16 University Of Southern California Polymorphisms in the ERCC1 gene for predicting treatment outcome
US8580498B2 (en) * 2002-11-15 2013-11-12 University Of South Florida Predictive value of nuclear excision repair genes for cancer survival
JP2006006313A (ja) * 2004-05-27 2006-01-12 Sumitomo Chemical Co Ltd コモンマーモセット由来のベータアクチン遺伝子及びその利用
AU2005249200A1 (en) * 2004-06-03 2005-12-15 F. Hoffmann-La Roche Ag Treatment with oxaliplatin and an EGFR-inhibitor
WO2006012361A2 (en) * 2004-07-01 2006-02-02 University Of Southern California Genetic markers for predicting disease and treatment outcome
EP2460886B1 (en) * 2005-05-04 2014-01-01 University of South Florida Predicting treatment response in cancer subjects
US20070054168A1 (en) * 2005-09-06 2007-03-08 Hao Chang Zinc/air cell
WO2007124314A2 (en) * 2006-04-20 2007-11-01 The Regents Of The University Of California Use of organic cation transporters for cancer diagnosis and therapy
EP2032980A4 (en) 2006-05-18 2012-01-04 Molecular Profiling Inst Inc SYSTEM AND METHOD FOR DETERMINING INDIVIDUALIZED MEDICAL USE AGAINST A SICKNESS STATE
US8768629B2 (en) * 2009-02-11 2014-07-01 Caris Mpi, Inc. Molecular profiling of tumors
US20080085881A1 (en) * 2006-10-06 2008-04-10 Aimery De Gramont Stop-and-go oxaliplatin treatment regimens
WO2008157353A1 (en) * 2007-06-15 2008-12-24 University Of South Florida Methods of diagnosing and treating cancer
EP2173874A2 (en) 2007-06-22 2010-04-14 Response Genetics, Inc Methods for isolating long fragment rna from fixed samples
US20110105529A1 (en) * 2008-05-15 2011-05-05 University Of Southern California ERCC-1 Gene Expression Predicts Chemotherapy Outcome
CA2727247A1 (en) * 2008-06-10 2009-12-17 University Of Southern California Thymidylate synthase haplotype is associated with tumor recurrence in stage ii and stage iii colon cancer patients
US7897356B2 (en) * 2008-11-12 2011-03-01 Caris Life Sciences Methods and systems of using exosomes for determining phenotypes
AU2011223789A1 (en) 2010-03-01 2012-09-20 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
US9469876B2 (en) 2010-04-06 2016-10-18 Caris Life Sciences Switzerland Holdings Gmbh Circulating biomarkers for metastatic prostate cancer
WO2013010074A1 (en) 2011-07-13 2013-01-17 Primeradx, Inc. Multimodal methods for simultaneous detection and quantification of multiple nucleic acids in a sample
CN102676661B (zh) * 2012-04-27 2014-12-31 中国人民解放军第四军医大学 基于荧光偏振的ERCC1基因第ll8位密码子单核苷酸多态性均相检测法
CN103088122A (zh) * 2012-12-07 2013-05-08 周宏灏 一种检测 TYMS mRNA 基因表达量的试剂盒及方法
CN105219881B (zh) * 2015-11-17 2018-11-20 东南大学 一种定量检测ercc1-202的试剂盒及应用

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4830969A (en) 1981-08-31 1989-05-16 The Research Foundation Of State University Of New York Process for the rapid and simple isolation of nucleic acids
EP0290144A1 (en) 1987-05-05 1988-11-09 City of Hope Method of detecting incipient resistance to therapeutic agents in cancer patients
US5085983A (en) 1988-08-19 1992-02-04 City Of Hope Detection of human tumor progression and drug resistance
US4843155A (en) 1987-11-19 1989-06-27 Piotr Chomczynski Product and process for isolating RNA
US5128247A (en) 1989-08-14 1992-07-07 Board Of Regents, The University Of Texas System Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources
US5672695A (en) * 1990-10-12 1997-09-30 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Modified ribozymes
US5284940A (en) 1990-11-14 1994-02-08 Hri Research, Inc. Preparation for nucleic acid samples
US5654179A (en) 1990-11-14 1997-08-05 Hri Research, Inc. Nucleic acid preparation methods
US5620852A (en) 1990-11-14 1997-04-15 Hri Research, Inc. Nucleic acid preparation methods
US5346994A (en) 1992-01-28 1994-09-13 Piotr Chomczynski Shelf-stable product and process for isolating RNA, DNA and proteins
US5502166A (en) 1992-02-26 1996-03-26 Mitsubishi Chemical Corporation NMDH receptor proteins and genes encoding the same
WO1994018156A1 (en) 1993-02-01 1994-08-18 University Of Iowa Research Foundation Quartenary amine surfactants and methods of using same in isolation of rna
US6613558B1 (en) * 1993-05-14 2003-09-02 Board Of Trustees Of Michigan State University Method for conversion of a halogenated hydrocarbon using a pseudomonas sp
US5637687A (en) 1993-08-31 1997-06-10 Wiggins; James C. Methods and compositions for isolating nucleic acids
US5502165A (en) * 1994-04-04 1996-03-26 Merck & Co., Inc. Process for peptide segment condensation
WO1995028489A1 (en) 1994-04-13 1995-10-26 The Uab Research Foundation Dihydropyrimidine dehydrogenase compositions and methods of use
US5643767A (en) 1994-05-02 1997-07-01 The Rockefeller University Process for isolating cellular components
CA2153215A1 (en) 1994-07-06 1996-01-07 Lu Wang Treatment of paraffin embedded tissue for gene analysis
US5707802A (en) 1995-01-13 1998-01-13 Ciba Corning Diagnostics Corp. Nucleic acid probes for the detection and identification of fungi
US5777099A (en) 1995-02-24 1998-07-07 Biotecx Laboratories, Inc. RNA separation
US5705336A (en) 1995-03-07 1998-01-06 The United States Of America As Represented By The Department Of Health And Human Services Assay for sensitivity of tumors to DNA-platinating chemotherapy
US5945515A (en) 1995-07-31 1999-08-31 Chomczynski; Piotr Product and process for isolating DNA, RNA and proteins
US5998151A (en) 1995-12-01 1999-12-07 The United States Of America As Represented By The Department Of Health And Human Services Methods for predicting the efficacy of a chemotherapeutic regimen for gastrointestinal cancers using antibodies specific for thymidylate synthase
US20020090642A1 (en) 1995-12-11 2002-07-11 Patrick G. Johnston Methods for determining the prognosis of breast cancer using antibodies specific for thymidylate synthase
DE29601618U1 (de) 1996-01-31 1996-07-04 InViTek GmbH, 13125 Berlin Vorrichtung zur gleichzeitigen multiplen Isolierung
EP0791654A1 (en) 1996-02-21 1997-08-27 Jürgen A. Dr. Richt Polypeptides corresponding to the amino acid sequences of proteins p57 or p9.5 of Borna disease virus, nucleic acid fragments coding therefore and their use for diagnostic and immunization purposes
EP0896629B8 (en) 1996-03-20 2003-01-02 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Methods and compositions for detecting dihydropyrimidine dehydrogenase splicing mutations
CA2253937A1 (en) 1996-05-10 1997-11-20 Phylomed Corporation Methods for oxidizing disulfide bonds using ozone
WO1998041648A2 (en) 1997-03-20 1998-09-24 Variagenics, Inc. Target genes for allele-specific drugs
CA2635001C (en) 1997-08-20 2012-12-04 Ervin Essenfeld High quality, continuous throughput, tissue fixation-dehydration-fat removal-impregnation
US5952202A (en) 1998-03-26 1999-09-14 The Perkin Elmer Corporation Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification
US6204375B1 (en) 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
KR20020007332A (ko) * 1999-03-18 2002-01-26 추후제출 일 단계 샘플 제조 및 복합적인 생물학적 샘플에서 핵산의검출
US6248535B1 (en) 1999-12-20 2001-06-19 University Of Southern California Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens
US6602670B2 (en) * 2000-12-01 2003-08-05 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 expression
US6518416B1 (en) 2000-12-01 2003-02-11 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 expression
US7049059B2 (en) * 2000-12-01 2006-05-23 Response Genetics, Inc. Method of determining a chemotherapeutic regimen based on ERCC1 and TS expression

Also Published As

Publication number Publication date
KR20030081339A (ko) 2003-10-17
CN1596314A (zh) 2005-03-16
AU2002246504B2 (en) 2007-03-29
US7732144B2 (en) 2010-06-08
TWI317759B (en) 2009-12-01
US20090311708A1 (en) 2009-12-17
AR031442A1 (es) 2003-09-24
CA2437038C (en) 2014-02-11
IL156232A (he) 2010-06-30
US20110212981A1 (en) 2011-09-01
EP1381691A2 (en) 2004-01-21
US20040009475A1 (en) 2004-01-15
CA2437038A1 (en) 2002-07-25
TWI327598B (en) 2010-07-21
MXPA03004928A (es) 2005-02-14
JP2004535771A (ja) 2004-12-02
ES2422302T3 (es) 2013-09-10
US20060121526A1 (en) 2006-06-08
CN1596314B (zh) 2011-06-22
TW200628614A (en) 2006-08-16
US7049059B2 (en) 2006-05-23
WO2002057489A3 (en) 2003-11-06
EP1381691B1 (en) 2013-04-24
WO2002057489A2 (en) 2002-07-25
US8586311B2 (en) 2013-11-19
US7560543B2 (en) 2009-07-14
JP5722569B2 (ja) 2015-05-20
NZ526711A (en) 2006-08-31
JP2011004756A (ja) 2011-01-13

Similar Documents

Publication Publication Date Title
TWI317759B (en) Method of determining a chemotherapeutic regimen based on ercc1 and ts expression
IL215130A0 (en) Method of determining a chemotherapeutic regimen based on ercci expression
GB2373060B (en) Method for fast and extensive formation evaluation
AU2001274285A1 (en) A leak detection apparatus and method
AU2001281098A1 (en) Tortuose path injection device and method
EE200000107A (et) Meetod mahuti avamisseadme valmistamiseks, selliselt valmistatud avamisseade ja sellega varustatud mahuti
GB0122515D0 (en) Berverage making appartus and method
AU8001501A (en) Geophone and method of manufacturing a geophone
AU771222C (en) Path timing detection circuit and detection method thereof
IL128017A0 (en) Method for detecting protein-protein interactions and a kit therefor
AU6296901A (en) Ion-sensitive, water-dispersible polymers, a method of making same and items using same
GB0016988D0 (en) Optical detection and analysis
IL151262A0 (en) Reagents and methods for detecting a reduced cofactor
AU2002218183A1 (en) Method for detecting the limit state of a material, and device therefor
GB0008787D0 (en) A method of cell detection
IL159301A0 (en) METHOD OF DETERMINING A CHEMOTHERAPEUTIC REGIMEN BASED ON GLUTATHIONE-S-TRANSFERASE Pi EXPRESSION
GB0026021D0 (en) Sensing apparatus and method
IL154069A0 (en) Method and device for characterising and/or for detecting a bonding complex
GB2358931B (en) Device and method for determining friction
AU7583100A (en) Molded closure with flex areas and method
AU2704101A (en) Arrival direction determining method and radio receiving device
IL162513A (en) Method and kit for detecting alkaline sphingomyelinase
AU9439501A (en) Discrimination between GnRH-I and GnRH-II
AUPR218400A0 (en) A method and device for determining a paging reference
EP0990218B8 (de) Verfahren zum selektiven erfassen und auslesen einer zeichenkette