IL155853A0 - Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases - Google Patents

Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases

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Publication number
IL155853A0
IL155853A0 IL15585301A IL15585301A IL155853A0 IL 155853 A0 IL155853 A0 IL 155853A0 IL 15585301 A IL15585301 A IL 15585301A IL 15585301 A IL15585301 A IL 15585301A IL 155853 A0 IL155853 A0 IL 155853A0
Authority
IL
Israel
Prior art keywords
medicaments
cardiovascular diseases
treating cardiovascular
substituted cyclohexane
cyclohexane derivatives
Prior art date
Application number
IL15585301A
Other languages
English (en)
Original Assignee
Bayer Ag
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Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL155853A0 publication Critical patent/IL155853A0/xx

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
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    • C07C233/68—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/73—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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    • C07C233/78—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

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IL15585301A 2000-11-24 2001-11-12 Substituted cyclohexane derivatives and the use thereof in medicaments for treating cardiovascular diseases IL155853A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10058461A DE10058461A1 (de) 2000-11-24 2000-11-24 Substituierte Cyclohexanderivate und ihre Verwendung
PCT/EP2001/013062 WO2002042257A1 (de) 2000-11-24 2001-11-12 Substituierte cyclohexanderivate und ihre verwendung in arzneimitteln zur behandlung von kardiovaskulären erkrankungen

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AU2002351731A1 (en) * 2001-12-14 2003-06-30 Novo Nordisk A/S Compounds and uses thereof for decreasing activity of hormone-sensitive lipase
TW200630337A (en) 2004-10-14 2006-09-01 Euro Celtique Sa Piperidinyl compounds and the use thereof
WO2007110449A1 (en) 2006-03-29 2007-10-04 Euro-Celtique S.A. Benzenesulfonamide compounds and their use
WO2007118854A1 (en) 2006-04-13 2007-10-25 Euro-Celtique S.A. Benzenesulfonamide compounds and the use thereof
US8791264B2 (en) 2006-04-13 2014-07-29 Purdue Pharma L.P. Benzenesulfonamide compounds and their use as blockers of calcium channels
EP2076261A2 (en) * 2006-10-03 2009-07-08 Ranbaxy Laboratories, Ltd. Muscarinic receptor antagonists
WO2008124118A1 (en) 2007-04-09 2008-10-16 Purdue Pharma L.P. Benzenesulfonyl compounds and the use therof
US8765736B2 (en) 2007-09-28 2014-07-01 Purdue Pharma L.P. Benzenesulfonamide compounds and the use thereof
KR102332892B1 (ko) 2019-11-27 2021-11-29 성균관대학교산학협력단 페닐시클로헥산카복스아마이드 화합물을 포함하는 발기부전의 예방, 개선 또는 치료용 조성물

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US20040235830A1 (en) 2004-11-25
CA2429328A1 (en) 2002-05-30
KR20030077542A (ko) 2003-10-01
BR0115611A (pt) 2004-01-06
JP2004522716A (ja) 2004-07-29
WO2002042257A1 (de) 2002-05-30
DE10058461A1 (de) 2002-09-19
MXPA03004537A (es) 2004-03-26
AU2002224839A1 (en) 2002-06-03
EP1339670A1 (de) 2003-09-03

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