IL151860A0 - Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating same - Google Patents
Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating sameInfo
- Publication number
- IL151860A0 IL151860A0 IL15186001A IL15186001A IL151860A0 IL 151860 A0 IL151860 A0 IL 151860A0 IL 15186001 A IL15186001 A IL 15186001A IL 15186001 A IL15186001 A IL 15186001A IL 151860 A0 IL151860 A0 IL 151860A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- single chain
- methods
- major histocompatibility
- constructs encoding
- Prior art date
Links
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000043129 MHC class I family Human genes 0.000 abstract 2
- 108091054437 MHC class I family Proteins 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compression, Expansion, Code Conversion, And Decoders (AREA)
- Steroid Compounds (AREA)
- Compression Of Band Width Or Redundancy In Fax (AREA)
- Processing Of Solid Wastes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53496600A | 2000-03-27 | 2000-03-27 | |
| PCT/IL2001/000260 WO2001072768A2 (en) | 2000-03-27 | 2001-03-19 | Single chain class i major histo-compatibility complexes, constructs encoding same and methods of generating same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL151860A0 true IL151860A0 (en) | 2003-04-10 |
Family
ID=24132253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15186001A IL151860A0 (en) | 2000-03-27 | 2001-03-19 | Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating same |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7399838B2 (https=) |
| EP (2) | EP2316950A1 (https=) |
| JP (1) | JP2004503213A (https=) |
| AT (1) | ATE472601T1 (https=) |
| AU (1) | AU785493B2 (https=) |
| CA (1) | CA2404489A1 (https=) |
| DE (1) | DE60142475D1 (https=) |
| IL (1) | IL151860A0 (https=) |
| WO (1) | WO2001072768A2 (https=) |
| ZA (1) | ZA200207515B (https=) |
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| DE60142475D1 (de) * | 2000-03-27 | 2010-08-12 | Technion Res And Dev Of Founda | Einkettige haupthistokompatibilitätskomplexe der klasse i (mhc-i), kodierende konstrukte und methoden ihrer erzeugung |
| US20040191260A1 (en) | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
| US8022190B2 (en) | 2001-06-19 | 2011-09-20 | Technion Research & Development Foundation Ltd. | Immuno-molecules containing viral proteins, compositions thereof and methods of using |
| US20030017134A1 (en) * | 2001-06-19 | 2003-01-23 | Technion Research And Development Foundation Ltd. | Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer |
| GB0115071D0 (en) * | 2001-06-20 | 2001-08-15 | Avidex Ltd | Substances |
| US6992176B2 (en) | 2002-02-13 | 2006-01-31 | Technion Research & Development Foundation Ltd. | Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease |
| AU2003216341A1 (en) | 2002-02-20 | 2003-09-09 | Dyax Corporation | Mhc-peptide complex binding ligands |
| US8895020B2 (en) * | 2002-04-19 | 2014-11-25 | Washington University | Single chain trimers and uses therefor |
| US20030199024A1 (en) * | 2002-04-19 | 2003-10-23 | Hansen Ted H. | Single chain trimers of class I MHC molecules |
| AU2003241127A1 (en) * | 2002-06-12 | 2003-12-31 | Gavish-Galilee Bio Applications Ltd | MEMBRANE-ANCHORED Beta2 MICROGLOBULIN COVALENTLY LINKED TO MHC CLASS I PEPTIDE EPITOPES |
| US20090233318A1 (en) * | 2004-12-28 | 2009-09-17 | Weidanz Jon A | Methods of assaying vaccine potency |
| US20090075304A1 (en) * | 2004-05-27 | 2009-03-19 | Weidanz Jon A | Methods of assaying vaccine potency |
| WO2005118791A1 (ja) * | 2004-06-03 | 2005-12-15 | National Institute Of Radiological Sciences | 微量試料を用いる網羅的遺伝子発現プロフィール解析法 |
| JP2008501781A (ja) * | 2004-06-09 | 2008-01-24 | テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド | 細胞の選択的アポトーシスのための抗体 |
| US8518697B2 (en) | 2006-04-04 | 2013-08-27 | Washington University | Single chain trimers and uses therefor |
| US7977457B2 (en) * | 2006-05-19 | 2011-07-12 | Teva Pharmaceutical Industries Ltd. | Fusion proteins, uses thereof and processes for producing same |
| US8394590B2 (en) * | 2006-08-02 | 2013-03-12 | California Institute Of Technology | Capture agents and related methods and systems for detecting and/or sorting targets |
| CA2682093A1 (en) | 2007-03-29 | 2008-10-09 | Technion Research & Development Foundation Ltd. | Antibodies, methods and kits for diagnosing and treating melanoma |
| US8747855B2 (en) | 2008-04-09 | 2014-06-10 | Technion Research & Development Foundation Limited | Anti human immunodeficiency antibodies and uses thereof |
| SI2119726T2 (en) | 2008-05-14 | 2018-03-30 | Immatics Biotechnologies Gmbh | New and powerful Class II MHC peptides derived from survivin and neurocane |
| PL2172211T3 (pl) | 2008-10-01 | 2015-05-29 | Immatics Biotechnologies Gmbh | Kompozycja związanych z guzem peptydów i związana z tym szczepionka przeciwrakowa do leczenia glejaka (GBM) i innych rodzajów raka |
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| WO2012145384A1 (en) * | 2011-04-20 | 2012-10-26 | University Of Washington Through Its Center For Commercialization | Beta-2 microglobulin-deficient cells |
| EA201400046A1 (ru) * | 2011-06-22 | 2014-07-30 | Ф. Хоффманн-Ля Рош Аг | Удаление клеток-мишеней с помощью циркулирующих вирусспецифических цитотоксических т-клеток с использованием содержащих гкгс класса i комплексов |
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| GB201505585D0 (en) | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
| AU2016243026B2 (en) | 2015-04-03 | 2022-03-31 | Eureka Therapeutics, Inc. | Constructs targeting AFP peptide/MHC complexes and uses thereof |
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| US5635363A (en) * | 1995-02-28 | 1997-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for the detection, quantitation and purification of antigen-specific T cells |
| US5869270A (en) * | 1996-01-31 | 1999-02-09 | Sunol Molecular Corporation | Single chain MHC complexes and uses thereof |
| CA2250166A1 (en) * | 1996-03-28 | 1997-10-02 | The Johns Hopkins University | Soluble divalent and multivalent heterodimeric analogs of proteins |
| US6140113A (en) * | 1996-03-28 | 2000-10-31 | The Johns Hopkins University | Polynucleotides encoding molecular complexes which modify immune responses |
| US6211342B1 (en) * | 1996-07-18 | 2001-04-03 | Children's Hospital Medical Center | Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function |
| US6248564B1 (en) * | 1997-08-29 | 2001-06-19 | Harvard University | Mutant MHC class I molecules |
| US6232445B1 (en) * | 1997-10-29 | 2001-05-15 | Sunol Molecular Corporation | Soluble MHC complexes and methods of use thereof |
| DE60142475D1 (de) * | 2000-03-27 | 2010-08-12 | Technion Res And Dev Of Founda | Einkettige haupthistokompatibilitätskomplexe der klasse i (mhc-i), kodierende konstrukte und methoden ihrer erzeugung |
| US8022190B2 (en) * | 2001-06-19 | 2011-09-20 | Technion Research & Development Foundation Ltd. | Immuno-molecules containing viral proteins, compositions thereof and methods of using |
| US20030017134A1 (en) * | 2001-06-19 | 2003-01-23 | Technion Research And Development Foundation Ltd. | Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer |
| US7362707B2 (en) * | 2001-07-23 | 2008-04-22 | Acme Packet, Inc. | System and method for determining flow quality statistics for real-time transport protocol data flows |
| US6843882B2 (en) * | 2002-07-15 | 2005-01-18 | Applied Materials, Inc. | Gas flow control in a wafer processing system having multiple chambers for performing same process |
| US7977457B2 (en) * | 2006-05-19 | 2011-07-12 | Teva Pharmaceutical Industries Ltd. | Fusion proteins, uses thereof and processes for producing same |
-
2001
- 2001-03-19 DE DE60142475T patent/DE60142475D1/de not_active Expired - Lifetime
- 2001-03-19 EP EP10166544A patent/EP2316950A1/en not_active Withdrawn
- 2001-03-19 IL IL15186001A patent/IL151860A0/xx unknown
- 2001-03-19 CA CA002404489A patent/CA2404489A1/en active Pending
- 2001-03-19 WO PCT/IL2001/000260 patent/WO2001072768A2/en not_active Ceased
- 2001-03-19 JP JP2001571699A patent/JP2004503213A/ja active Pending
- 2001-03-19 EP EP01914159A patent/EP1294748B1/en not_active Expired - Lifetime
- 2001-03-19 AT AT01914159T patent/ATE472601T1/de not_active IP Right Cessation
- 2001-03-19 AU AU39534/01A patent/AU785493B2/en not_active Ceased
-
2002
- 2002-02-13 US US10/073,300 patent/US7399838B2/en not_active Expired - Fee Related
- 2002-02-15 US US10/075,257 patent/US20040086960A1/en not_active Abandoned
- 2002-09-19 ZA ZA200207515A patent/ZA200207515B/en unknown
-
2008
- 2008-06-18 US US12/213,368 patent/US20090148925A1/en not_active Abandoned
-
2009
- 2009-06-18 US US12/486,794 patent/US20090258393A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200207515B (en) | 2004-07-21 |
| WO2001072768A8 (en) | 2005-11-17 |
| AU3953401A (en) | 2001-10-08 |
| US20090258393A1 (en) | 2009-10-15 |
| US7399838B2 (en) | 2008-07-15 |
| DE60142475D1 (de) | 2010-08-12 |
| AU785493B2 (en) | 2008-01-03 |
| JP2004503213A (ja) | 2004-02-05 |
| WO2001072768A3 (en) | 2003-01-23 |
| US20040086960A1 (en) | 2004-05-06 |
| EP1294748B1 (en) | 2010-06-30 |
| EP1294748A4 (en) | 2004-10-06 |
| ATE472601T1 (de) | 2010-07-15 |
| EP1294748A2 (en) | 2003-03-26 |
| US20090148925A1 (en) | 2009-06-11 |
| WO2001072768A2 (en) | 2001-10-04 |
| CA2404489A1 (en) | 2001-10-04 |
| US20030003535A1 (en) | 2003-01-02 |
| EP2316950A1 (en) | 2011-05-04 |
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