IL151860A0 - Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating same - Google Patents
Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating sameInfo
- Publication number
- IL151860A0 IL151860A0 IL15186001A IL15186001A IL151860A0 IL 151860 A0 IL151860 A0 IL 151860A0 IL 15186001 A IL15186001 A IL 15186001A IL 15186001 A IL15186001 A IL 15186001A IL 151860 A0 IL151860 A0 IL 151860A0
- Authority
- IL
- Israel
- Prior art keywords
- same
- single chain
- methods
- major histocompatibility
- constructs encoding
- Prior art date
Links
- 230000020382 suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I Effects 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 102000043129 MHC class I family Human genes 0.000 abstract 2
- 108091054437 MHC class I family Proteins 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Compression, Expansion, Code Conversion, And Decoders (AREA)
- Compression Of Band Width Or Redundancy In Fax (AREA)
- Processing Of Solid Wastes (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53496600A | 2000-03-27 | 2000-03-27 | |
| PCT/IL2001/000260 WO2001072768A2 (en) | 2000-03-27 | 2001-03-19 | Single chain class i major histo-compatibility complexes, constructs encoding same and methods of generating same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL151860A0 true IL151860A0 (en) | 2003-04-10 |
Family
ID=24132253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15186001A IL151860A0 (en) | 2000-03-27 | 2001-03-19 | Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating same |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US7399838B2 (https=) |
| EP (2) | EP2316950A1 (https=) |
| JP (1) | JP2004503213A (https=) |
| AT (1) | ATE472601T1 (https=) |
| AU (1) | AU785493B2 (https=) |
| CA (1) | CA2404489A1 (https=) |
| DE (1) | DE60142475D1 (https=) |
| IL (1) | IL151860A0 (https=) |
| WO (1) | WO2001072768A2 (https=) |
| ZA (1) | ZA200207515B (https=) |
Families Citing this family (74)
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| US20040191260A1 (en) | 2003-03-26 | 2004-09-30 | Technion Research & Development Foundation Ltd. | Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof |
| IL151860A0 (en) * | 2000-03-27 | 2003-04-10 | Technion Res & Dev Foundation | Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating same |
| US20030017134A1 (en) * | 2001-06-19 | 2003-01-23 | Technion Research And Development Foundation Ltd. | Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer |
| US8022190B2 (en) | 2001-06-19 | 2011-09-20 | Technion Research & Development Foundation Ltd. | Immuno-molecules containing viral proteins, compositions thereof and methods of using |
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| US8895020B2 (en) * | 2002-04-19 | 2014-11-25 | Washington University | Single chain trimers and uses therefor |
| ATE509025T1 (de) * | 2002-06-12 | 2011-05-15 | Gavish Galilee Bio Appl Ltd | ßMIT MHC-KLASSE-I-PEPTIDEPITOPEN KOVALENT VERKN PFTES MEMBRANVERANKERTES BETA2-MIKROGLOBULINß |
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| US8518697B2 (en) | 2006-04-04 | 2013-08-27 | Washington University | Single chain trimers and uses therefor |
| KR101442209B1 (ko) | 2006-05-19 | 2014-11-18 | 테크니온 리서치 엔드 디벨로프먼트 화운데이션 엘티디. | 융합 단백질, 이의 용도 및 이의 제조방법 |
| US8394590B2 (en) * | 2006-08-02 | 2013-03-12 | California Institute Of Technology | Capture agents and related methods and systems for detecting and/or sorting targets |
| EP2144935A2 (en) | 2007-03-29 | 2010-01-20 | Technion Research & Development Foundation Ltd. | Antibodies, methods and kits for diagnosing and treating melanoma |
| EP2280731A1 (en) | 2008-04-09 | 2011-02-09 | Technion Research and Development Foundation, Ltd. | Anti human immunodeficiency antibodies and uses thereof |
| ES2532896T5 (es) | 2008-05-14 | 2018-03-20 | Immatics Biotechnologies Gmbh | Péptidos del MHC de clase II novedosos y potentes derivados de survivina y neurocan |
| RS53782B1 (sr) | 2008-10-01 | 2015-06-30 | Immatics Biotechnologies Gmbh | Preparati tumor-asociranih peptida i odgovarajuća antikancerska vakcina za tretman glioblastoma (gbm) i drugih kancera |
| EP2184297A1 (en) * | 2008-11-07 | 2010-05-12 | Hla-G Technologies | HLA-G polypeptides and pharmaceutical uses thereof |
| CA3205636A1 (en) * | 2011-04-20 | 2012-10-26 | University Of Washington Through Its Center For Commercialization | Beta-2 microglobulin-deficient cells |
| CN103649125A (zh) * | 2011-06-22 | 2014-03-19 | 霍夫曼-拉罗奇有限公司 | 利用包含mhc i类的复合物通过循环中的病毒特异性细胞毒性t细胞清除靶细胞 |
| TWI636065B (zh) | 2013-08-05 | 2018-09-21 | 伊瑪提克斯生物科技有限公司 | 新穎肽類，細胞及其用於治療多種腫瘤的用途，其製造方法及包含其等之醫藥組成物 |
| GB201319446D0 (en) | 2013-11-04 | 2013-12-18 | Immatics Biotechnologies Gmbh | Personalized immunotherapy against several neuronal and brain tumors |
| GB201408255D0 (en) | 2014-05-09 | 2014-06-25 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumours of the blood, such as acute myeloid leukemia (AML) |
| GB201411037D0 (en) | 2014-06-20 | 2014-08-06 | Immatics Biotechnologies Gmbh | Novel immunotherapy against several tumors of the blood, in particular chronic lymphoid leukemai (CLL) |
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| LT3388075T (lt) | 2015-03-27 | 2023-11-10 | Immatics Biotechnologies Gmbh | Nauji peptidai ir peptidų deriniai, skirti naudoti imunoterapijai prieš įvairius navikus (seq id 25 - mrax5-003) |
| GB201505585D0 (en) | 2015-03-31 | 2015-05-13 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carinoma (RCC) and other cancers |
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| GB201507030D0 (en) | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
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| AU2016274767B2 (en) | 2015-06-09 | 2022-05-19 | Eureka Therapeutics, Inc. | T cell receptor-like antibody agents specific for EBV latent membrane protein 2A peptide presented by human HLA |
| MA54884A (fr) | 2015-07-01 | 2022-01-12 | Immatics Biotechnologies Gmbh | Neuartige peptide und kombination aus peptiden zur verwendung in der immuntherapie gegen ovarialkarzinom und andere karzinome |
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| TWI796299B (zh) | 2016-08-26 | 2023-03-21 | 德商英麥提克生物技術股份有限公司 | 用於頭頸鱗狀細胞癌和其他癌症免疫治療的新型肽和支架 |
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| US10925947B2 (en) | 2018-06-29 | 2021-02-23 | Immatics Biotechnologies Gmbh | A*03 restricted peptides for use in immunotherapy against cancers and related methods |
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| EP4021493A1 (en) | 2019-08-29 | 2022-07-06 | Eberhard Karls Universität Tübingen, Medizinische Fakultät | T cell epitopes of hcmv and uses of thereof |
| DE102020125465A1 (de) | 2020-09-29 | 2022-03-31 | Immatics Biotechnologies Gmbh | Amidierte Peptide und ihre deamidierten Gegenstücke, die durch nicht-HLA-A*02-Moleküle präsentiert werden, zur Verwendung in der Immuntherapie gegen verschiedene Krebsarten |
| TW202229312A (zh) | 2020-09-29 | 2022-08-01 | 德商英麥提克生物技術股份有限公司 | 由非ｈｌａ－ａ*０２顯露以用於不同類型癌症之免疫治療的醯胺化肽及其脫醯胺化對應物 |
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| TW202241925A (zh) | 2021-01-15 | 2022-11-01 | 德商英麥提克生物技術股份有限公司 | 用於不同類型癌症免疫治療的ｈｌａ展示肽 |
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| US6140113A (en) * | 1996-03-28 | 2000-10-31 | The Johns Hopkins University | Polynucleotides encoding molecular complexes which modify immune responses |
| US6211342B1 (en) * | 1996-07-18 | 2001-04-03 | Children's Hospital Medical Center | Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function |
| US6248564B1 (en) * | 1997-08-29 | 2001-06-19 | Harvard University | Mutant MHC class I molecules |
| US6232445B1 (en) * | 1997-10-29 | 2001-05-15 | Sunol Molecular Corporation | Soluble MHC complexes and methods of use thereof |
| IL151860A0 (en) * | 2000-03-27 | 2003-04-10 | Technion Res & Dev Foundation | Single chain class i major histocompatibility complexes, constructs encoding same and methods of generating same |
| US8022190B2 (en) * | 2001-06-19 | 2011-09-20 | Technion Research & Development Foundation Ltd. | Immuno-molecules containing viral proteins, compositions thereof and methods of using |
| US20030017134A1 (en) * | 2001-06-19 | 2003-01-23 | Technion Research And Development Foundation Ltd. | Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer |
| US7362707B2 (en) * | 2001-07-23 | 2008-04-22 | Acme Packet, Inc. | System and method for determining flow quality statistics for real-time transport protocol data flows |
| US6843882B2 (en) * | 2002-07-15 | 2005-01-18 | Applied Materials, Inc. | Gas flow control in a wafer processing system having multiple chambers for performing same process |
| KR101442209B1 (ko) * | 2006-05-19 | 2014-11-18 | 테크니온 리서치 엔드 디벨로프먼트 화운데이션 엘티디. | 융합 단백질, 이의 용도 및 이의 제조방법 |
-
2001
- 2001-03-19 IL IL15186001A patent/IL151860A0/xx unknown
- 2001-03-19 AT AT01914159T patent/ATE472601T1/de not_active IP Right Cessation
- 2001-03-19 DE DE60142475T patent/DE60142475D1/de not_active Expired - Lifetime
- 2001-03-19 JP JP2001571699A patent/JP2004503213A/ja active Pending
- 2001-03-19 WO PCT/IL2001/000260 patent/WO2001072768A2/en not_active Ceased
- 2001-03-19 AU AU39534/01A patent/AU785493B2/en not_active Ceased
- 2001-03-19 EP EP10166544A patent/EP2316950A1/en not_active Withdrawn
- 2001-03-19 CA CA002404489A patent/CA2404489A1/en active Pending
- 2001-03-19 EP EP01914159A patent/EP1294748B1/en not_active Expired - Lifetime
-
2002
- 2002-02-13 US US10/073,300 patent/US7399838B2/en not_active Expired - Fee Related
- 2002-02-15 US US10/075,257 patent/US20040086960A1/en not_active Abandoned
- 2002-09-19 ZA ZA200207515A patent/ZA200207515B/en unknown
-
2008
- 2008-06-18 US US12/213,368 patent/US20090148925A1/en not_active Abandoned
-
2009
- 2009-06-18 US US12/486,794 patent/US20090258393A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU785493B2 (en) | 2008-01-03 |
| US20090258393A1 (en) | 2009-10-15 |
| US20090148925A1 (en) | 2009-06-11 |
| WO2001072768A8 (en) | 2005-11-17 |
| ATE472601T1 (de) | 2010-07-15 |
| EP1294748B1 (en) | 2010-06-30 |
| US20030003535A1 (en) | 2003-01-02 |
| WO2001072768A3 (en) | 2003-01-23 |
| EP1294748A4 (en) | 2004-10-06 |
| WO2001072768A2 (en) | 2001-10-04 |
| CA2404489A1 (en) | 2001-10-04 |
| US7399838B2 (en) | 2008-07-15 |
| ZA200207515B (en) | 2004-07-21 |
| AU3953401A (en) | 2001-10-08 |
| EP2316950A1 (en) | 2011-05-04 |
| EP1294748A2 (en) | 2003-03-26 |
| JP2004503213A (ja) | 2004-02-05 |
| DE60142475D1 (de) | 2010-08-12 |
| US20040086960A1 (en) | 2004-05-06 |
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