IL149340A0 - Nucleic acids encoding endotheliases, endotheliases and uses thereof - Google Patents
Nucleic acids encoding endotheliases, endotheliases and uses thereofInfo
- Publication number
- IL149340A0 IL149340A0 IL14934000A IL14934000A IL149340A0 IL 149340 A0 IL149340 A0 IL 149340A0 IL 14934000 A IL14934000 A IL 14934000A IL 14934000 A IL14934000 A IL 14934000A IL 149340 A0 IL149340 A0 IL 149340A0
- Authority
- IL
- Israel
- Prior art keywords
- endotheliases
- nucleic acids
- acids encoding
- screening
- portions
- Prior art date
Links
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 108091005804 Peptidases Proteins 0.000 abstract 3
- 239000004365 Protease Substances 0.000 abstract 3
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000012216 screening Methods 0.000 abstract 2
- 102000035195 Peptidases Human genes 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000002889 endothelial cell Anatomy 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Surgery (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16639199P | 1999-11-18 | 1999-11-18 | |
US23484000P | 2000-09-22 | 2000-09-22 | |
PCT/US2000/031803 WO2001036604A2 (en) | 1999-11-18 | 2000-11-17 | Nucleic acids encoding endotheliases, endotheliases and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
IL149340A0 true IL149340A0 (en) | 2002-11-10 |
Family
ID=26862218
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14934000A IL149340A0 (en) | 1999-11-18 | 2000-11-17 | Nucleic acids encoding endotheliases, endotheliases and uses thereof |
Country Status (11)
Country | Link |
---|---|
US (1) | US7276364B1 (ko) |
EP (1) | EP1230349B1 (ko) |
JP (1) | JP2003514524A (ko) |
KR (1) | KR20020056923A (ko) |
AT (1) | ATE364689T1 (ko) |
AU (1) | AU784746B2 (ko) |
CA (1) | CA2387805C (ko) |
DE (1) | DE60035218D1 (ko) |
IL (1) | IL149340A0 (ko) |
RU (1) | RU2002113076A (ko) |
WO (1) | WO2001036604A2 (ko) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1230349B1 (en) | 1999-11-18 | 2007-06-13 | Dendreon Corporation | Nucleic acids encoding endotheliases, endotheliases and uses thereof |
US20020031801A1 (en) * | 2000-03-24 | 2002-03-14 | Millennium Pharmaceuticals, Inc. | 18806, a novel trypsin serine protease-like molecule and uses thereof |
ES2305093T3 (es) | 2000-06-13 | 2008-11-01 | Bayer Healthcare Ag | Regulacion de la serina proteasa transmembrana humana. |
CA2412013A1 (en) * | 2000-06-20 | 2001-12-27 | Human Genome Sciences, Inc. | Polynucleotides encoding human serine proteases |
EP1545572A4 (en) * | 2001-05-23 | 2006-04-12 | Dendreon Corp | CELL SURFACE PROTEINS ACTIVATED CONJUGATES AND THERAPEUTIC USES THEREOF |
AU2002310492A1 (en) * | 2001-06-20 | 2003-01-08 | Immunex Corporation | Dendritic cell transmembrane serine protease |
CA2535859A1 (en) * | 2003-08-14 | 2005-03-03 | Dyax Corp. | Endotheliase-2 ligands |
WO2005023835A2 (en) * | 2003-09-09 | 2005-03-17 | Irm Llc | Modulators of transmembrane protease serine 6 |
KR100783670B1 (ko) * | 2006-05-22 | 2007-12-07 | 한국표준과학연구원 | 도메인 단백질을 이용한 생리활성물질의 검색 방법 |
Family Cites Families (100)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8372A (en) | 1851-09-16 | Milton d | ||
US107266A (en) | 1870-09-13 | Improvement in molds for drying cigar-fillings | ||
US37857A (en) | 1863-03-10 | Improvement in molds for castings | ||
US160962A (en) | 1875-03-16 | Improvement in seal-locks | ||
US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
US3630200A (en) | 1969-06-09 | 1971-12-28 | Alza Corp | Ocular insert |
US3940475A (en) | 1970-06-11 | 1976-02-24 | Biological Developments, Inc. | Radioimmune method of assaying quantitatively for a hapten |
US4006117A (en) | 1973-01-24 | 1977-02-01 | Hooker Chemicals & Plastics Corporation | Amine phosphite antioxidants |
US3843443A (en) | 1973-03-30 | 1974-10-22 | J Fishman | Polypeptide materials bound to fluorocarbon polymers |
US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
US3846770A (en) | 1973-07-11 | 1974-11-05 | Us Navy | Serial access memory using magnetic domains in thin film strips |
US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
JPS6023084B2 (ja) | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
US4640835A (en) | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
US4507230A (en) | 1982-05-12 | 1985-03-26 | Research Corporation | Peptide synthesis reagents and method of use |
US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
US4952496A (en) | 1984-03-30 | 1990-08-28 | Associated Universities, Inc. | Cloning and expression of the gene for bacteriophage T7 RNA polymerase |
US5346823A (en) | 1984-05-29 | 1994-09-13 | Genencor, Inc. | Subtilisin modifications to enhance oxidative stability |
US4769027A (en) | 1984-08-15 | 1988-09-06 | Burroughs Wellcome Co. | Delivery system |
DE3500180A1 (de) | 1985-01-04 | 1986-07-10 | Ernst Prof. Dr. 7400 Tübingen Bayer | Pfropfcopolymerisate aus vernetzten polymeren und polyoxyethylen, verfahren zu ihrer herstellung und ihre verwendung |
EP0206448B1 (en) | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hemoglobin combined with a poly(alkylene oxide) |
US4980286A (en) | 1985-07-05 | 1990-12-25 | Whitehead Institute For Biomedical Research | In vivo introduction and expression of foreign genetic material in epithelial cells |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
US4687610A (en) | 1986-04-30 | 1987-08-18 | E. I. Du Pont De Neumours And Company | Low crystallinity polyester yarn produced at ultra high spinning speeds |
US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
DE3626468A1 (de) | 1986-08-05 | 1988-02-11 | Hoechst Ag | Verfahren und testkit zur bestimmung freier wirkstoffe in biologischen fluessigkeiten |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
US5292814A (en) | 1987-04-29 | 1994-03-08 | Ernst Bayer | Process for the preparation of monodispersed polymer beads |
US4904582A (en) | 1987-06-11 | 1990-02-27 | Synthetic Genetics | Novel amphiphilic nucleic acid conjugates |
US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
US5925525A (en) | 1989-06-07 | 1999-07-20 | Affymetrix, Inc. | Method of identifying nucleotide differences |
US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
US5215899A (en) | 1989-11-09 | 1993-06-01 | Miles Inc. | Nucleic acid amplification employing ligatable hairpin probe and transcription |
US6552170B1 (en) | 1990-04-06 | 2003-04-22 | Amgen Inc. | PEGylation reagents and compounds formed therewith |
US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
US5256643A (en) | 1990-05-29 | 1993-10-26 | The Government Of The United States | Human cripto protein |
US5401629A (en) | 1990-08-07 | 1995-03-28 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Assay methods and compositions useful for measuring the transduction of an intracellular signal |
JPH07500961A (ja) | 1990-10-01 | 1995-02-02 | ユニバーシティ オブ コネチカット | 細胞による選択的内在化を目的としたウイルス及び細胞の標的設定 |
WO1992011933A1 (en) | 1991-01-04 | 1992-07-23 | Perseptive Biosystems, Inc. | Sulfonamide bonded hydrophilic coatings |
WO1992020316A2 (en) | 1991-05-14 | 1992-11-26 | University Of Connecticut | Targeted delivery of genes encoding immunogenic proteins |
AU2160992A (en) | 1991-06-05 | 1993-01-12 | Board Of Regents Acting For And On Behalf Of The University Of Michigan, The | Targeted delivery of genes encoding secretory proteins |
US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
AU3434393A (en) | 1992-01-17 | 1993-08-03 | Regents Of The University Of Michigan, The | Targeted virus |
JPH07505773A (ja) | 1992-04-03 | 1995-06-29 | ヤング アレキサンダー ティー | 標的化されたウイルスベクターを用いた遺伝子治療 |
DK0644771T4 (da) | 1992-06-11 | 2006-12-27 | Alkermes Inc | Lægemiddelsystem til levering af erythropoietin |
WO1994005807A1 (en) | 1992-08-28 | 1994-03-17 | Dickson Robert B | Matrix-degrading metalloproteinase |
AU689758B2 (en) | 1992-10-09 | 1998-04-09 | Advanced Tissue Sciences, Inc. | Liver reserve cells |
US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
US5354934A (en) | 1993-02-04 | 1994-10-11 | Amgen Inc. | Pulmonary administration of erythropoietin |
US5629327A (en) | 1993-03-01 | 1997-05-13 | Childrens Hospital Medical Center Corp. | Methods and compositions for inhibition of angiogenesis |
US5354566A (en) | 1993-06-02 | 1994-10-11 | Kraft General Foods, Inc. | Preparation of yeast-leavened dough crusts |
AU700315B2 (en) | 1993-10-28 | 1998-12-24 | Houston Advanced Research Center | Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions |
IL112759A0 (en) | 1994-02-25 | 1995-05-26 | Khepri Pharmaceuticals Inc | Novel cysteine protease inhibitors |
US5612474A (en) | 1994-06-30 | 1997-03-18 | Eli Lilly And Company | Acid labile immunoconjugate intermediates |
IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
US5627765A (en) | 1994-07-25 | 1997-05-06 | Avid Technology, Inc. | Method and apparatus for compressing and analyzing video and for creating a reference video |
US5804410A (en) * | 1994-07-29 | 1998-09-08 | Teijin Limited | Nucleic acid sequence encoding trypsin-like enzyme and process for producing the enzyme |
US5589154A (en) | 1994-11-22 | 1996-12-31 | Rutgers, The State University Of New Jersey | Methods for the prevention or treatment of vascular hemorrhaging and Alzheimer's disease |
NZ305626A (en) | 1995-03-24 | 2000-01-28 | Axys Pharm Inc | Reversible protease inhibitors |
US5869451A (en) | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
ES2293651T3 (es) | 1995-11-28 | 2008-03-16 | Cephalon, Inc. | Inhibidores de cisteina y serina proteasas derivados de aminoacidos d. |
WO2000012708A2 (en) * | 1998-09-01 | 2000-03-09 | Genentech, Inc. | Further pro polypeptides and sequences thereof |
WO2000078961A1 (en) | 1999-06-23 | 2000-12-28 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US20030073129A1 (en) * | 1998-09-01 | 2003-04-17 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US7160985B2 (en) * | 1997-10-29 | 2007-01-09 | Genentech, Inc. | Pro180 polypeptide |
US6150378A (en) | 1997-10-07 | 2000-11-21 | Cephalon, Inc. | Peptidyl-containing α-ketoamide cysteine and serine protease inhibitors |
US6203979B1 (en) | 1998-01-16 | 2001-03-20 | Incyte Pharmaceuticals, Inc. | Human protease molecules |
US5972616A (en) | 1998-02-20 | 1999-10-26 | The Board Of Trustees Of The University Of Arkansas | TADG-15: an extracellular serine protease overexpressed in breast and ovarian carcinomas |
DK1490386T3 (da) | 1998-03-10 | 2008-12-15 | Genentech Inc | Nyt polypeptid og nukleinsyrer kodende for dette |
AU759150B2 (en) * | 1998-09-01 | 2003-04-03 | Genentech Inc. | Further pro polypeptides and sequences thereof |
WO2001054477A2 (en) | 2000-01-25 | 2001-08-02 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
AU3223100A (en) | 1999-02-05 | 2000-08-25 | Alphagene, Inc. | Proteomic interaction arrays |
AU1068900A (en) * | 1999-02-26 | 2000-09-14 | Ohio State University Research Foundation, The | Detecting the expression of the desc1 gene in squamous cell carcinoma |
US6291663B1 (en) | 1999-03-03 | 2001-09-18 | Board Of Trustees Of The University Of Arkansas | TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma |
EP1263948A2 (en) | 1999-03-08 | 2002-12-11 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
CA2362670A1 (en) | 1999-03-12 | 2000-09-14 | Georgetown University | Matriptase, a serine protease and its applications |
EP1159260A1 (en) | 1999-03-15 | 2001-12-05 | Axys Pharmaceuticals, Inc. | Novel compounds and compositions as protease inhibitors |
US20030175938A1 (en) * | 1999-05-07 | 2003-09-18 | Human Genome Sciences, Inc. | Serine protease polynucleotides, polypeptides, and antibodies |
WO2000068247A2 (en) | 1999-05-07 | 2000-11-16 | Human Genome Sciences, Inc. | Serine proteases |
EP1194569A2 (en) | 1999-07-12 | 2002-04-10 | MERCK PATENT GmbH | Seripancrin |
US20020165376A1 (en) | 1999-12-22 | 2002-11-07 | Walke D. Wade | Novel human proteases and polynucleotides encoding the same |
AU1630501A (en) | 1999-10-08 | 2001-04-23 | Superarray, Inc. | Compositions and methods for detecting protein modification and enzymatic activity |
WO2001036645A2 (en) | 1999-11-17 | 2001-05-25 | Curagen Corporation | Serine/threonine kinase and serine protease polypeptides and nucleic acids encoding same |
EP1230349B1 (en) | 1999-11-18 | 2007-06-13 | Dendreon Corporation | Nucleic acids encoding endotheliases, endotheliases and uses thereof |
WO2001036351A2 (en) | 1999-11-19 | 2001-05-25 | Corvas International, Inc. | Plasminogen activator inhibitor antagonists related applications |
CA2402360A1 (en) | 2000-01-06 | 2001-07-12 | Lexicon Genetics Incorporated | Novel human proteases and polynucleotides encoding the same |
WO2001055441A2 (en) | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
ATE496123T1 (de) | 2000-02-03 | 2011-02-15 | Dendreon Corp | Nukleinsäuren, welche für tramsmembran serin proteasen kodieren, die kodierten proteine und darauf basierende methoden |
AU6802801A (en) | 2000-03-01 | 2001-09-24 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US20020064856A1 (en) * | 2000-06-26 | 2002-05-30 | Gregory Plowman | Novel proteases |
AU2002224553A1 (en) * | 2000-07-21 | 2002-02-05 | Incyte Genomics, Inc. | Human proteases |
US6365391B1 (en) | 2000-09-27 | 2002-04-02 | Pe Corporation (Ny) | Isolated human serine protease, nucleic acid molecules encoding human serine protease, and uses thereof |
-
2000
- 2000-11-17 EP EP00978819A patent/EP1230349B1/en not_active Expired - Lifetime
- 2000-11-17 IL IL14934000A patent/IL149340A0/xx unknown
- 2000-11-17 JP JP2001538483A patent/JP2003514524A/ja active Pending
- 2000-11-17 AU AU16239/01A patent/AU784746B2/en not_active Ceased
- 2000-11-17 DE DE60035218T patent/DE60035218D1/de not_active Expired - Lifetime
- 2000-11-17 CA CA2387805A patent/CA2387805C/en not_active Expired - Fee Related
- 2000-11-17 WO PCT/US2000/031803 patent/WO2001036604A2/en active IP Right Grant
- 2000-11-17 RU RU2002113076/13A patent/RU2002113076A/ru not_active Application Discontinuation
- 2000-11-17 KR KR1020027006388A patent/KR20020056923A/ko not_active Application Discontinuation
- 2000-11-17 AT AT00978819T patent/ATE364689T1/de not_active IP Right Cessation
- 2000-11-20 US US09/717,473 patent/US7276364B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2387805A1 (en) | 2001-05-25 |
AU784746B2 (en) | 2006-06-08 |
AU1623901A (en) | 2001-05-30 |
CA2387805C (en) | 2012-08-28 |
WO2001036604A2 (en) | 2001-05-25 |
EP1230349A2 (en) | 2002-08-14 |
DE60035218D1 (de) | 2007-07-26 |
WO2001036604A3 (en) | 2001-11-01 |
EP1230349B1 (en) | 2007-06-13 |
ATE364689T1 (de) | 2007-07-15 |
RU2002113076A (ru) | 2004-03-10 |
KR20020056923A (ko) | 2002-07-10 |
US7276364B1 (en) | 2007-10-02 |
JP2003514524A (ja) | 2003-04-22 |
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