IL148031A0 - Torsemide polymorphs - Google Patents
Torsemide polymorphsInfo
- Publication number
- IL148031A0 IL148031A0 IL14803100A IL14803100A IL148031A0 IL 148031 A0 IL148031 A0 IL 148031A0 IL 14803100 A IL14803100 A IL 14803100A IL 14803100 A IL14803100 A IL 14803100A IL 148031 A0 IL148031 A0 IL 148031A0
- Authority
- IL
- Israel
- Prior art keywords
- torsemide
- polymorphs
- torsemide polymorphs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
- Pressure Welding/Diffusion-Bonding (AREA)
- Details Of Garments (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14830599P | 1999-08-11 | 1999-08-11 | |
US18312700P | 2000-02-17 | 2000-02-17 | |
US21527300P | 2000-06-30 | 2000-06-30 | |
PCT/US2000/022081 WO2001010441A1 (en) | 1999-08-11 | 2000-08-11 | Torsemide polymorphs |
Publications (1)
Publication Number | Publication Date |
---|---|
IL148031A0 true IL148031A0 (en) | 2002-09-12 |
Family
ID=27386674
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14803100A IL148031A0 (en) | 1999-08-11 | 2000-08-11 | Torsemide polymorphs |
Country Status (24)
Country | Link |
---|---|
US (1) | US6465496B1 (zh) |
EP (1) | EP1207880A4 (zh) |
JP (1) | JP2003527319A (zh) |
KR (1) | KR20020025217A (zh) |
CN (1) | CN1378448A (zh) |
AU (1) | AU781461C (zh) |
BG (1) | BG106400A (zh) |
CA (1) | CA2379322A1 (zh) |
CZ (1) | CZ2002404A3 (zh) |
DE (1) | DE00957398T1 (zh) |
ES (1) | ES2204354T1 (zh) |
HK (1) | HK1046636A1 (zh) |
HR (1) | HRP20020120A2 (zh) |
HU (1) | HUP0204318A3 (zh) |
IL (1) | IL148031A0 (zh) |
LT (1) | LT5004B (zh) |
MX (1) | MXPA02001369A (zh) |
NO (1) | NO20020622L (zh) |
PL (1) | PL354262A1 (zh) |
SI (1) | SI20816A (zh) |
SK (1) | SK1912002A3 (zh) |
TR (1) | TR200200353T2 (zh) |
WO (1) | WO2001010441A1 (zh) |
YU (1) | YU9502A (zh) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2193007T3 (es) * | 2000-02-17 | 2004-11-01 | Teva Pharmaceutical Industries Ltd. | Formulacion farmaceutica estable que comprende la modificacion ii de la torsemida. |
DE10013289A1 (de) * | 2000-03-17 | 2001-09-20 | Knoll Ag | Torasemid enthaltende pharmazeutische Zubereitungen |
HRP20000162B1 (en) | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
US20030022921A1 (en) * | 2001-02-21 | 2003-01-30 | Minutza Leibovici | Stable pharmaceutical formulation comprising torsemide modification II |
EP1397343A1 (en) | 2001-05-31 | 2004-03-17 | Orion Corporation Fermion | Process for preparing sertraline hydrochloride polymorphic form ii |
IN192178B (zh) * | 2001-08-03 | 2004-03-06 | Ranbaxy Lab | |
US20030119882A1 (en) * | 2001-10-22 | 2003-06-26 | Markus Maegerlein | Solid pharmaceutical composition containing torasemide |
ITMI20020639A1 (it) * | 2002-03-27 | 2003-09-29 | Cosma S P A | Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea |
HRP20020603B1 (en) * | 2002-07-19 | 2008-11-30 | Pliva D.D. | New process for the preparation of modification i n-(1-methylethylaminocarbonyl)-4-(3-methylphenylamino)-3-pyridinesulfonamide |
CA2424644A1 (en) * | 2003-04-07 | 2004-10-07 | David John Mckenzie | Preparation of torasemide |
ES2244324B1 (es) * | 2004-03-25 | 2006-11-16 | Ferrer Internacional, S.A. | Composiciones diureticas de liberacion prolongada. |
AT500576B1 (de) * | 2004-07-28 | 2006-11-15 | Sanochemia Pharmazeutika Ag | Verfahren zur reindarstellung von kristallformen von torsemid |
KR100845383B1 (ko) * | 2004-12-24 | 2008-07-09 | 일동제약주식회사 | 토르세미드 변형체(ⅰ)의 제조방법 |
US20070122483A1 (en) * | 2005-11-29 | 2007-05-31 | Sharon Myers | Fluocinolone acetonide drug substance polymorphic interconversion |
AU2014348523B2 (en) | 2013-11-15 | 2019-01-03 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof |
CN105949115A (zh) * | 2016-05-26 | 2016-09-21 | 南京正科医药股份有限公司 | 一种新晶型托拉塞米 |
CN115417810B (zh) * | 2022-09-22 | 2023-10-10 | 南京正科医药股份有限公司 | 一种托拉塞米晶型ⅰ的精制方法 |
CN117486789A (zh) * | 2023-12-29 | 2024-02-02 | 江西中医药大学 | 一种托拉塞米共晶盐及其制备方法和应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US34672A (en) | 1862-03-18 | Improved convertible boat, bridge, and tent | ||
US30633A (en) | 1860-11-13 | Improvement in fire-escapes | ||
GB1477664A (en) * | 1974-04-17 | 1977-06-22 | Christiaens Sa A | Pyridine derivatives |
US4055650A (en) * | 1974-04-17 | 1977-10-25 | A. Christiaens Societe Anonyme | Certain 4-phenoxy(or phenylthio)-3-n-acylated-sulfonamido-pyridines |
DE3529529A1 (de) | 1985-08-17 | 1987-02-19 | Boehringer Mannheim Gmbh | Verfahren zur herstellung einer stabilen modifikation von torasemid |
DE3623620A1 (de) | 1986-07-12 | 1988-01-21 | Boehringer Mannheim Gmbh | Spritzfertige, waessrige, alkalische injektionsloesungen von torasemid und verfahren zu ihrer herstellung |
HRP980532B1 (en) * | 1998-10-02 | 2005-06-30 | Pliva | Novel crystalline torasemide modification |
US5914336A (en) * | 1998-06-02 | 1999-06-22 | Boehringer Mannheim Gmbh | Method of controlling the serum solubility of orally administered torasemide and composition relating thereto |
US6166045A (en) * | 1998-06-02 | 2000-12-26 | Roche Diagnostics Gmbh | Torasemide of modification III |
CZ20023395A3 (cs) * | 2000-03-20 | 2003-04-16 | Teva Pharmaceutical Industries Ltd. | Nový způsob přípravy meziproduktu torsemidu |
HRP20000162B1 (en) * | 2000-03-20 | 2004-06-30 | Pliva D D | Amorphous torasemide modification |
HRP20000328A2 (en) * | 2000-05-19 | 2002-02-28 | Pliva Farmaceutska Ind Dionik | Novel polymorph v of torasemide |
-
2000
- 2000-08-11 YU YU9502A patent/YU9502A/sh unknown
- 2000-08-11 HU HU0204318A patent/HUP0204318A3/hu unknown
- 2000-08-11 JP JP2001514958A patent/JP2003527319A/ja not_active Withdrawn
- 2000-08-11 KR KR1020027001867A patent/KR20020025217A/ko not_active Application Discontinuation
- 2000-08-11 IL IL14803100A patent/IL148031A0/xx unknown
- 2000-08-11 PL PL00354262A patent/PL354262A1/xx not_active Application Discontinuation
- 2000-08-11 MX MXPA02001369A patent/MXPA02001369A/es unknown
- 2000-08-11 EP EP00957398A patent/EP1207880A4/en not_active Withdrawn
- 2000-08-11 SK SK191-2002A patent/SK1912002A3/sk unknown
- 2000-08-11 AU AU69026/00A patent/AU781461C/en not_active Ceased
- 2000-08-11 WO PCT/US2000/022081 patent/WO2001010441A1/en active IP Right Grant
- 2000-08-11 US US09/638,106 patent/US6465496B1/en not_active Expired - Fee Related
- 2000-08-11 SI SI200020037A patent/SI20816A/sl not_active IP Right Cessation
- 2000-08-11 CZ CZ2002404A patent/CZ2002404A3/cs unknown
- 2000-08-11 DE DE0001207880T patent/DE00957398T1/de active Pending
- 2000-08-11 CN CN00814045A patent/CN1378448A/zh active Pending
- 2000-08-11 ES ES00957398T patent/ES2204354T1/es active Pending
- 2000-08-11 CA CA002379322A patent/CA2379322A1/en not_active Abandoned
- 2000-08-11 TR TR2002/00353T patent/TR200200353T2/xx unknown
-
2002
- 2002-02-08 BG BG106400A patent/BG106400A/xx unknown
- 2002-02-08 NO NO20020622A patent/NO20020622L/no not_active Application Discontinuation
- 2002-02-08 HR HR20020120A patent/HRP20020120A2/hr not_active Application Discontinuation
- 2002-02-11 LT LT2002017A patent/LT5004B/lt unknown
- 2002-11-08 HK HK02108111.5A patent/HK1046636A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
KR20020025217A (ko) | 2002-04-03 |
AU6902600A (en) | 2001-03-05 |
ES2204354T1 (es) | 2004-05-01 |
MXPA02001369A (es) | 2005-08-26 |
YU9502A (sh) | 2005-06-10 |
PL354262A1 (en) | 2003-12-29 |
AU781461B2 (en) | 2005-05-26 |
TR200200353T2 (tr) | 2002-06-21 |
JP2003527319A (ja) | 2003-09-16 |
EP1207880A1 (en) | 2002-05-29 |
CN1378448A (zh) | 2002-11-06 |
LT2002017A (en) | 2002-11-25 |
SK1912002A3 (en) | 2002-07-02 |
EP1207880A4 (en) | 2004-09-01 |
WO2001010441A1 (en) | 2001-02-15 |
HK1046636A1 (zh) | 2003-01-24 |
NO20020622D0 (no) | 2002-02-08 |
DE00957398T1 (de) | 2004-04-15 |
HRP20020120A2 (en) | 2003-10-31 |
US6465496B1 (en) | 2002-10-15 |
LT5004B (lt) | 2003-03-25 |
AU781461C (en) | 2006-02-23 |
NO20020622L (no) | 2002-03-14 |
HUP0204318A2 (en) | 2003-05-28 |
SI20816A (sl) | 2002-08-31 |
CZ2002404A3 (cs) | 2002-06-12 |
HUP0204318A3 (en) | 2005-03-29 |
CA2379322A1 (en) | 2001-02-15 |
BG106400A (en) | 2002-08-30 |
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