IL146745A0 - Activation and protection of cytotoxic lymphocytes using a reactive oxygen metabolite inhibitor - Google Patents
Activation and protection of cytotoxic lymphocytes using a reactive oxygen metabolite inhibitorInfo
- Publication number
- IL146745A0 IL146745A0 IL14674500A IL14674500A IL146745A0 IL 146745 A0 IL146745 A0 IL 146745A0 IL 14674500 A IL14674500 A IL 14674500A IL 14674500 A IL14674500 A IL 14674500A IL 146745 A0 IL146745 A0 IL 146745A0
- Authority
- IL
- Israel
- Prior art keywords
- activation
- protection
- reactive oxygen
- cytotoxic lymphocytes
- oxygen metabolite
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
- A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/44—Oxidoreductases (1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01006—Catalase (1.11.1.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01009—Glutathione peroxidase (1.11.1.9)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y111/00—Oxidoreductases acting on a peroxide as acceptor (1.11)
- C12Y111/01—Peroxidases (1.11.1)
- C12Y111/01011—L-ascorbate peroxidase (1.11.1.11)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55544—Bacterial toxins
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14439499P | 1999-07-16 | 1999-07-16 | |
PCT/US2000/019407 WO2001006756A2 (en) | 1999-07-16 | 2000-07-14 | Use of diphenyliodonium for the activation and protection of cytotoxic lymphocytes |
Publications (1)
Publication Number | Publication Date |
---|---|
IL146745A0 true IL146745A0 (en) | 2002-07-25 |
Family
ID=22508390
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14674500A IL146745A0 (en) | 1999-07-16 | 2000-07-14 | Activation and protection of cytotoxic lymphocytes using a reactive oxygen metabolite inhibitor |
Country Status (12)
Country | Link |
---|---|
US (1) | US20040120926A1 (ja) |
EP (1) | EP1200074A2 (ja) |
JP (1) | JP2003505348A (ja) |
KR (1) | KR20020016844A (ja) |
CN (1) | CN1379664A (ja) |
AU (1) | AU779215B2 (ja) |
CA (1) | CA2377247A1 (ja) |
HK (1) | HK1046368A1 (ja) |
IL (1) | IL146745A0 (ja) |
NZ (1) | NZ515859A (ja) |
WO (1) | WO2001006756A2 (ja) |
ZA (1) | ZA200109655B (ja) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2004258801A1 (en) * | 2003-02-28 | 2005-02-03 | Inotek Pharmaceuticals Corporation | Tetracyclic Benzamide Derivatives and methods of use thereof |
EP1722797A4 (en) * | 2004-02-26 | 2008-03-19 | Inotek Pharmaceuticals Corp | ISOCHINOLINE DERIVATIVES AND METHOD FOR THE APPLICATION THEREOF |
WO2005082079A2 (en) * | 2004-02-26 | 2005-09-09 | Inotek Pharmaceuticals Corporation | Tetracyclic lactam derivatives and uses thereof |
JP2008503466A (ja) * | 2004-06-16 | 2008-02-07 | イノテック ファーマシューティカルズ コーポレイション | 勃起不全または尿失禁を治療または予防する方法 |
WO2006039545A2 (en) * | 2004-09-30 | 2006-04-13 | Maxim Pharmaceuticals, Inc. | Use of parp-1 inhibitors for protecting tumorcidal lymphocytes from apoptosis |
KR20070116016A (ko) * | 2005-02-25 | 2007-12-06 | 이노텍 파마슈티컬스 코포레이션 | 이소퀴놀린 화합물 및 그의 이용 방법 |
KR20070116011A (ko) * | 2005-02-25 | 2007-12-06 | 이노텍 파마슈티컬스 코포레이션 | 테트라사이클릭 아미노 및 카복사미도 화합물 및 이의 이용방법 |
US20060287311A1 (en) * | 2005-02-25 | 2006-12-21 | Inotek Pharmaceuticals Corporation | Tetracyclic Sulfonamide Compounds and methods of use thereof |
CA2613631A1 (en) * | 2005-06-23 | 2007-01-04 | Spherics, Inc. | Improved dosage forms for movement disorder treatment |
JP2009506060A (ja) * | 2005-08-24 | 2009-02-12 | イノテック ファーマシューティカルズ コーポレイション | インデノイソキノリノン類縁体及びそれらの使用方法 |
US20080131492A1 (en) * | 2006-06-23 | 2008-06-05 | Spherics, Inc. | Dosage forms for movement disorder treatment |
CA2673511A1 (en) * | 2006-12-22 | 2008-07-03 | Combinatorx, Incorporated | Pharmaceutical compositions for treatment of parkinson's disease and related disorders |
CA2677046A1 (en) * | 2007-02-28 | 2008-09-04 | Inotek Pharmaceuticals Corporation | Indenoisoquinolinone analogs and methods of use thereof |
JP6556121B2 (ja) * | 2013-04-29 | 2019-08-07 | アポジェニックス アーゲー | 癌を診断する方法 |
WO2019023263A1 (en) * | 2017-07-25 | 2019-01-31 | Immune Pharmaceuticals, Inc. | METHODS AND COMPOSITIONS FOR TREATING TUMORS COMPRISING A BCR-ABL1 FUSION GENE |
EP3700512A4 (en) * | 2017-10-24 | 2021-08-11 | Lunella Biotech, Inc. | MITOFLAVOSCINE: TARGETING FLAVINAL ENZYMES ELIMINATES CANCER STEM CELLS (CSCS) BY INHIBITING MITOCHONDRIAL BREATHING |
KR102053545B1 (ko) | 2018-08-30 | 2019-12-06 | 동아대학교 산학협력단 | 디페닐리오도니움을 포함하는 항진균 및 항균용 조성물 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA741203B (en) * | 1973-03-23 | 1975-01-29 | Smithkline Corp | Veterinary feed compositions for inhibiting rumen microbial deamination |
ES2087163T3 (es) * | 1989-09-19 | 1996-07-16 | Syntello Inc | Preparacion antitumoral que comprende intreleucina-2 e histamina, analogo al de las mismas o agonistas de receptor h2. |
US5686436A (en) * | 1993-05-13 | 1997-11-11 | Hiv Diagnostics, Inc. | Multi-faceted method to repress reproduction of latent viruses in humans and animals |
US5780513A (en) * | 1996-08-22 | 1998-07-14 | Washington University | Method of inhibiting the release of bioactive IL-1 |
US6498181B1 (en) * | 1999-01-06 | 2002-12-24 | Maxim Pharmaceuticals | Synergistic tumorcidal response induced by histamine |
-
2000
- 2000-07-14 CA CA002377247A patent/CA2377247A1/en not_active Abandoned
- 2000-07-14 AU AU61044/00A patent/AU779215B2/en not_active Ceased
- 2000-07-14 JP JP2001511077A patent/JP2003505348A/ja active Pending
- 2000-07-14 IL IL14674500A patent/IL146745A0/xx unknown
- 2000-07-14 KR KR1020017016560A patent/KR20020016844A/ko not_active Application Discontinuation
- 2000-07-14 WO PCT/US2000/019407 patent/WO2001006756A2/en not_active Application Discontinuation
- 2000-07-14 CN CN00810484A patent/CN1379664A/zh active Pending
- 2000-07-14 EP EP00947434A patent/EP1200074A2/en not_active Withdrawn
- 2000-07-14 NZ NZ515859A patent/NZ515859A/xx unknown
-
2001
- 2001-11-23 ZA ZA200109655A patent/ZA200109655B/en unknown
-
2002
- 2002-11-01 HK HK02107968.1A patent/HK1046368A1/zh unknown
-
2003
- 2003-10-07 US US10/680,865 patent/US20040120926A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20040120926A1 (en) | 2004-06-24 |
WO2001006756A2 (en) | 2001-01-25 |
KR20020016844A (ko) | 2002-03-06 |
JP2003505348A (ja) | 2003-02-12 |
CA2377247A1 (en) | 2001-01-25 |
AU6104400A (en) | 2001-02-05 |
CN1379664A (zh) | 2002-11-13 |
ZA200109655B (en) | 2002-10-30 |
NZ515859A (en) | 2004-02-27 |
HK1046368A1 (zh) | 2003-01-10 |
EP1200074A2 (en) | 2002-05-02 |
WO2001006756A3 (en) | 2001-11-15 |
AU779215B2 (en) | 2005-01-13 |
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