IL144945A0 - Aromatic sulfone hydroxamic acid metalloprotease inhibitor - Google Patents

Aromatic sulfone hydroxamic acid metalloprotease inhibitor

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Publication number
IL144945A0
IL144945A0 IL14494500A IL14494500A IL144945A0 IL 144945 A0 IL144945 A0 IL 144945A0 IL 14494500 A IL14494500 A IL 14494500A IL 14494500 A IL14494500 A IL 14494500A IL 144945 A0 IL144945 A0 IL 144945A0
Authority
IL
Israel
Prior art keywords
hydroxamic acid
metalloprotease inhibitor
aromatic sulfone
sulfone hydroxamic
acid metalloprotease
Prior art date
Application number
IL14494500A
Other languages
English (en)
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of IL144945A0 publication Critical patent/IL144945A0/xx

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    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
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    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
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IL14494500A 1999-02-24 2000-02-22 Aromatic sulfone hydroxamic acid metalloprotease inhibitor IL144945A0 (en)

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US09/256,948 US20010039287A1 (en) 1997-11-14 1999-02-24 Aromatic sulfone hydroxamic acid metalloprotease inhibitor
PCT/US2000/002518 WO2000050396A1 (fr) 1999-02-24 2000-02-22 Inhibiteur de metalloprotease a base d'acide hydroxamique aromatique sulfoné

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CA2371876A1 (fr) 2000-08-31
CN1370144A (zh) 2002-09-18
CZ20013038A3 (cs) 2002-07-17
HUP0200239A3 (en) 2003-04-28
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AU3478500A (en) 2000-09-14
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US20010039287A1 (en) 2001-11-08

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