IL144031A0 - Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents - Google Patents

Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents

Info

Publication number
IL144031A0
IL144031A0 IL14403199A IL14403199A IL144031A0 IL 144031 A0 IL144031 A0 IL 144031A0 IL 14403199 A IL14403199 A IL 14403199A IL 14403199 A IL14403199 A IL 14403199A IL 144031 A0 IL144031 A0 IL 144031A0
Authority
IL
Israel
Prior art keywords
substituted
compositions containing
receptor binding
binding agents
progesterone receptor
Prior art date
Application number
IL14403199A
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IL144031A0 publication Critical patent/IL144031A0/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/42Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/28Nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/42Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54Nitrogen and either oxygen or sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/041,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/061,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL14403199A 1999-01-14 1999-12-14 Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents IL144031A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23190699A 1999-01-14 1999-01-14
PCT/US1999/029601 WO2000042031A2 (en) 1999-01-14 1999-12-14 Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents

Publications (1)

Publication Number Publication Date
IL144031A0 true IL144031A0 (en) 2002-04-21

Family

ID=22871101

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14403199A IL144031A0 (en) 1999-01-14 1999-12-14 Substituted 2-arylimino heterocycles and compositions containing them, for use as progesterone receptor binding agents

Country Status (21)

Country Link
EP (1) EP1144396A2 (en)
JP (1) JP2002534517A (en)
KR (1) KR20010089831A (en)
CN (1) CN1337955A (en)
AR (1) AR022214A1 (en)
AU (1) AU2708700A (en)
BG (1) BG105761A (en)
BR (1) BR9916999A (en)
CA (1) CA2359562A1 (en)
CO (1) CO5160338A1 (en)
CZ (1) CZ20012530A3 (en)
GT (1) GT200000003A (en)
HU (1) HUP0105134A2 (en)
ID (1) ID30514A (en)
IL (1) IL144031A0 (en)
NO (1) NO20013318L (en)
SK (1) SK10032001A3 (en)
SV (1) SV2002000005A (en)
TR (1) TR200102041T2 (en)
WO (1) WO2000042031A2 (en)
ZA (1) ZA200105253B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0202429A3 (en) * 1999-08-31 2004-04-28 Schering Ag Use of mesoprogestins (progesterone receptor modulators) for the preparation of pharmaceutical compositions for the treatment and prevention of benign hormone dependent gynecological disorders
US8193252B1 (en) 1999-08-31 2012-06-05 Bayer Pharma AG Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders
CO5200773A1 (en) * 1999-08-31 2002-09-27 Jenapharm Gmbh And Co Kg MESOPROGESTINES (RECEIVER MODULATORS FOR PROGESTERON) AS A COMPONENT OF COMPOSITIONS USED FOR HORMONAL REPLACEMENT THERAPY (HRT)
DE60038687T2 (en) 1999-09-14 2009-05-28 Shionogi & Co., Ltd. 2-imino-1,3-thiazine derivatives
EP1277743A4 (en) * 2000-03-28 2005-03-23 Nippon Soda Co Oxa(thia)zolidine derivative and anti-inflammatory drug
BR0107179A (en) * 2000-09-07 2002-07-02 Bayer Ag Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binding agents
JP4188694B2 (en) * 2001-03-08 2008-11-26 塩野義製薬株式会社 Pharmaceutical composition containing a 1,3-thiazine derivative
US7189751B2 (en) 2001-06-25 2007-03-13 Nippon Soda Co., Ltd. Oxa(thia)zolidine compounds, process for preparation thereof and anti-inflammatory agents
ES2367539T3 (en) 2001-12-21 2011-11-04 X-Ceptor Therapeutics, Inc. HETEROCYCLIC MODULATORS OF NUCLEAR RECEPTORS.
EP1636167A2 (en) * 2003-06-10 2006-03-22 SmithKline Beecham Corporation 1-aminonaphthalenes as modulators of androgen, glucocorticoid, mineralocorticoid and progesterone receptors
CN103382158B (en) * 2013-07-29 2015-11-18 张家港市大伟助剂有限公司 A kind of preparation method of 2-clopentylamino ethanol
KR20220034151A (en) * 2019-07-10 2022-03-17 바이엘 악티엔게젤샤프트 Method for preparing 2-(phenylimino)-1,3-thiazolidin-4-one
CN114507143A (en) * 2022-02-26 2022-05-17 江苏壹药新材料有限公司 Synthesis method of 2-ethyl-1-fluoro-4-nitrobenzene
CN114671828B (en) * 2022-04-28 2024-05-31 蔚林新材料科技股份有限公司 Preparation method of 3-methyl-2-thiazole thioketone
CN114957288B (en) * 2022-06-07 2024-02-13 苏州华道生物药业股份有限公司 Synthesis method of tetramisole hydrochloride
CN115925559A (en) * 2022-11-11 2023-04-07 上海泰坦科技股份有限公司 Preparation method of 1-amino-1-cyclopentyl methanol

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670754A1 (en) * 1966-09-27 1970-12-23 Bayer Ag Process for the preparation of 2-phenylimino-oxazolidines
FR1510015A (en) * 1966-12-05 1968-01-19 Aquitaine Petrole Preparation of imino-thiazolidines
DE1767335A1 (en) * 1968-04-27 1971-09-02 Bayer Ag Anesthetic for animals
DE1963193A1 (en) * 1969-12-17 1971-06-24 Bayer Ag N-substituted 2-arylimino-oxazolidines, process for their preparation and their use as ectoparasiticides
FR2117337A5 (en) * 1970-12-04 1972-07-21 Eastman Kodak Co Merocyanine dye sensitisers - contg basic and acidic gps for silver halide emulsions
US3787575A (en) * 1970-12-17 1974-01-22 Bayer Ag N-substituted-2-arylimino-oxazolidines used as acaricides
GB1342232A (en) * 1971-07-29 1974-01-03 Bayer Ag Aryliminothiazolidines a process for their preparation and their use as acaricides
CH614946A5 (en) * 1975-05-07 1979-12-28 Ciba Geigy Ag
DE2658138A1 (en) * 1976-12-22 1978-07-06 Bayer Ag 2-Phenyl-imino-4-hydroxy-thiazolidine derivs. - useful as ectoparasiticides, esp. against acarids
DE2926771A1 (en) * 1979-07-03 1981-01-15 Hoechst Ag THIAZOLIDE DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF
DE3049460A1 (en) * 1980-12-30 1982-07-29 Hoechst Ag, 6000 Frankfurt "THIAZOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS
DE3505432A1 (en) * 1985-02-16 1986-08-21 Hoechst Ag, 6230 Frankfurt Crop protection agents and pesticides based on thiazolidine derivatives, novel thiazolidine derivatives, and their preparation
IL84175A0 (en) * 1986-10-17 1988-03-31 Stauffer Chemical Co Iminooxazolidines,their preparation and their use as herbicides
US4806653A (en) * 1986-10-17 1989-02-21 Stauffer Chemical Company Process for preparation of iminooxazolidines
ATE63907T1 (en) * 1986-11-04 1991-06-15 Duphar Int Res SUBSTITUTED 2-PHENYLIMINO-OXAZOLIDINE DERIVATIVES WITH HERBICIDAL ACTIVITY.
AU2717488A (en) * 1987-11-19 1989-06-14 Chevron Research Company Ectoparasiticides

Also Published As

Publication number Publication date
ID30514A (en) 2001-12-13
CA2359562A1 (en) 2000-07-20
CO5160338A1 (en) 2002-05-30
EP1144396A2 (en) 2001-10-17
HUP0105134A2 (en) 2002-04-29
WO2000042031A3 (en) 2000-11-09
NO20013318D0 (en) 2001-07-04
TR200102041T2 (en) 2001-12-21
WO2000042031A2 (en) 2000-07-20
NO20013318L (en) 2001-08-30
JP2002534517A (en) 2002-10-15
BR9916999A (en) 2001-10-30
AR022214A1 (en) 2002-09-04
BG105761A (en) 2002-03-29
ZA200105253B (en) 2002-09-05
GT200000003A (en) 2001-07-06
KR20010089831A (en) 2001-10-08
SK10032001A3 (en) 2002-05-09
SV2002000005A (en) 2002-07-16
CN1337955A (en) 2002-02-27
CZ20012530A3 (en) 2002-02-13
AU2708700A (en) 2000-08-01

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