IL143834A0 - Insulin-like growth factor (igf) i mutant variants - Google Patents

Insulin-like growth factor (igf) i mutant variants

Info

Publication number
IL143834A0
IL143834A0 IL14383400A IL14383400A IL143834A0 IL 143834 A0 IL143834 A0 IL 143834A0 IL 14383400 A IL14383400 A IL 14383400A IL 14383400 A IL14383400 A IL 14383400A IL 143834 A0 IL143834 A0 IL 143834A0
Authority
IL
Israel
Prior art keywords
igf
insulin
growth factor
mutant variants
mutant
Prior art date
Application number
IL14383400A
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL143834A0 publication Critical patent/IL143834A0/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
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    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • A—HUMAN NECESSITIES
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    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A—HUMAN NECESSITIES
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    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
IL14383400A 1999-01-06 2000-01-05 Insulin-like growth factor (igf) i mutant variants IL143834A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11501099P 1999-01-06 1999-01-06
PCT/US2000/000151 WO2000040612A1 (en) 1999-01-06 2000-01-05 Insulin-like growth factor (igf) i mutant variants

Publications (1)

Publication Number Publication Date
IL143834A0 true IL143834A0 (en) 2002-04-21

Family

ID=22358799

Family Applications (3)

Application Number Title Priority Date Filing Date
IL14383400A IL143834A0 (en) 1999-01-06 2000-01-05 Insulin-like growth factor (igf) i mutant variants
IL143834A IL143834A (en) 1999-01-06 2001-06-19 Igf-like insulin variant
IL186608A IL186608A (en) 1999-01-06 2007-10-11 Insulin-like growth factor variants (igf – i)

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL143834A IL143834A (en) 1999-01-06 2001-06-19 Igf-like insulin variant
IL186608A IL186608A (en) 1999-01-06 2007-10-11 Insulin-like growth factor variants (igf – i)

Country Status (12)

Country Link
US (6) US6509443B1 (xx)
EP (1) EP1141015B1 (xx)
JP (3) JP2002535967A (xx)
AU (1) AU762047B2 (xx)
CA (1) CA2356257C (xx)
CY (1) CY1109452T1 (xx)
DE (1) DE60042550D1 (xx)
DK (1) DK1141015T3 (xx)
ES (1) ES2329220T3 (xx)
IL (3) IL143834A0 (xx)
PT (1) PT1141015E (xx)
WO (1) WO2000040612A1 (xx)

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BRPI0715754A2 (pt) * 2006-08-31 2013-07-09 Hoffmann La Roche mÉtodo para a produÇço de fator do crescimento similar Á insulina i
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EP2328607A1 (en) * 2008-07-16 2011-06-08 Arecor Limited Stable formulation of a therapeutic protein
CA2726230A1 (en) * 2009-07-16 2010-08-19 Arecor Limited The stabilisation of proteins
JP5571186B2 (ja) * 2009-07-22 2014-08-13 イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ ５９位にアミノ酸置換を有するインスリン様増殖因子−１（ｉｇｆ−１）の類似体
MX2012002901A (es) * 2009-09-10 2012-06-27 Lonza Biologics Plc Metodo y sistema para purificacion de polipeptidos.
US20110152188A1 (en) * 2009-12-23 2011-06-23 Hanns-Christian Mahler Pharmaceutical compositions of igf/i proteins
WO2011146902A1 (en) 2010-05-21 2011-11-24 Merrimack Pharmaceuticals, Inc. Bi-specific fusion proteins
EA201291482A1 (ru) 2010-07-09 2013-10-30 Байоджен Айдек Хемофилия Инк. Химерные факторы коагуляции
WO2013012733A1 (en) 2011-07-15 2013-01-24 Biogen Idec Ma Inc. Heterodimeric fc regions, binding molecules comprising same, and methods relating thereto
WO2013106577A2 (en) 2012-01-10 2013-07-18 Biogen Idec Ma Inc. Enhancement of transport of therapeutic molecules across the blood brain barrier
SI2935320T1 (sl) * 2012-12-18 2019-12-31 Novartis Ag Stabilizirani polipeptidi inzulinu podobnega rastnega faktorja
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CA2356257C (en) 2012-10-16
US20040033952A1 (en) 2004-02-19
JP4467549B2 (ja) 2010-05-26
DK1141015T3 (da) 2010-01-25
EP1141015B1 (en) 2009-07-15
US6506874B1 (en) 2003-01-14
US20030191065A1 (en) 2003-10-09
IL186608A0 (en) 2008-01-20
IL186608A (en) 2014-06-30
DE60042550D1 (de) 2009-08-27
JP2005139203A (ja) 2005-06-02
PT1141015E (pt) 2009-10-13
AU762047B2 (en) 2003-06-19
IL143834A (en) 2008-07-08
US6509443B1 (en) 2003-01-21
WO2000040612A9 (en) 2001-03-22
EP1141015A1 (en) 2001-10-10
US20040033951A1 (en) 2004-02-19
JP2007045829A (ja) 2007-02-22
AU2719400A (en) 2000-07-24
US20040023883A1 (en) 2004-02-05
ES2329220T3 (es) 2009-11-24
WO2000040612A1 (en) 2000-07-13
CY1109452T1 (el) 2014-08-13

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