IL143182A0 - Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group - Google Patents
Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine groupInfo
- Publication number
- IL143182A0 IL143182A0 IL14318299A IL14318299A IL143182A0 IL 143182 A0 IL143182 A0 IL 143182A0 IL 14318299 A IL14318299 A IL 14318299A IL 14318299 A IL14318299 A IL 14318299A IL 143182 A0 IL143182 A0 IL 143182A0
- Authority
- IL
- Israel
- Prior art keywords
- herpes viruses
- heterocyclic carboxamide
- phenylenediamine group
- thiourea inhibitors
- inhibitors
- Prior art date
Links
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 title 2
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical group NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 title 1
- -1 Heterocyclic carboxamide Chemical class 0.000 title 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 241001529453 unidentified herpesvirus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/06—1,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20855998A | 1998-12-09 | 1998-12-09 | |
| PCT/US1999/028842 WO2000034258A2 (en) | 1998-12-09 | 1999-12-06 | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL143182A0 true IL143182A0 (en) | 2002-04-21 |
Family
ID=22775044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL14318299A IL143182A0 (en) | 1998-12-09 | 1999-12-06 | Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1144397A3 (cs) |
| JP (1) | JP2002531554A (cs) |
| CN (1) | CN1348446A (cs) |
| AU (1) | AU1934700A (cs) |
| BG (1) | BG105581A (cs) |
| BR (1) | BR9916046A (cs) |
| CA (1) | CA2350767A1 (cs) |
| CZ (1) | CZ20011956A3 (cs) |
| EA (1) | EA200100631A1 (cs) |
| HU (1) | HUP0200232A2 (cs) |
| ID (1) | ID30158A (cs) |
| IL (1) | IL143182A0 (cs) |
| NO (1) | NO20012832L (cs) |
| PL (1) | PL349217A1 (cs) |
| SK (1) | SK7682001A3 (cs) |
| TR (1) | TR200101664T2 (cs) |
| WO (1) | WO2000034258A2 (cs) |
| ZA (1) | ZA200104377B (cs) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6166028A (en) * | 1998-12-09 | 2000-12-26 | American Home Products Corporation | Diaminopuridine-containing thiourea inhibitors of herpes viruses |
| US6844367B1 (en) | 1999-09-17 | 2005-01-18 | Millennium Pharmaceuticals, Inc. | Benzamides and related inhibitors of factor Xa |
| ATE311366T1 (de) | 2000-02-29 | 2005-12-15 | Millennium Pharm Inc | Benzamide und ähnliche inhibitoren vom faktor xa |
| US7220768B2 (en) * | 2003-02-11 | 2007-05-22 | Wyeth Holdings Corp. | Isoxazole-containing thiourea inhibitors useful for treatment of varicella zoster virus |
| PT2077995E (pt) | 2006-11-02 | 2012-05-10 | Millennium Pharm Inc | Métodos de sintetizar sais farmacêuticos de um inibidor de fator xa |
| WO2014070979A1 (en) * | 2012-11-03 | 2014-05-08 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
| WO2014070978A1 (en) * | 2012-11-03 | 2014-05-08 | Boehringer Ingelheim International Gmbh | Inhibitors of cytomegalovirus |
| CN110565100B (zh) * | 2019-07-12 | 2021-05-07 | 西北工业大学 | 一种二茂钴阳离子基缓蚀剂及制备方法和使用方法 |
| WO2023011574A1 (zh) | 2021-08-05 | 2023-02-09 | 浙江海正药业股份有限公司 | 芳香乙炔类衍生物及其制备方法和用途 |
| EP4433479A1 (en) | 2021-11-19 | 2024-09-25 | Basf Se | Bicyclic compounds for the control of invertebrate pests |
| CN115433093A (zh) * | 2022-09-26 | 2022-12-06 | 无锡双启科技有限公司 | 一种3-氯-4-三氟甲基苯胺的制备方法 |
| CN115710190A (zh) * | 2022-11-16 | 2023-02-24 | 常州佳德医药科技有限公司 | 4-甲氧基-2-氨基-n,n-二甲基苯胺、制备方法及应用 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE298741T1 (de) * | 1997-04-10 | 2005-07-15 | Pharmacia & Upjohn Co Llc | Polyaromatische verbindungen zur behandlung von herpes-infektionen |
-
1999
- 1999-12-06 PL PL99349217A patent/PL349217A1/xx not_active Application Discontinuation
- 1999-12-06 JP JP2000586705A patent/JP2002531554A/ja active Pending
- 1999-12-06 TR TR2001/01664T patent/TR200101664T2/xx unknown
- 1999-12-06 EA EA200100631A patent/EA200100631A1/ru unknown
- 1999-12-06 WO PCT/US1999/028842 patent/WO2000034258A2/en not_active Application Discontinuation
- 1999-12-06 SK SK768-2001A patent/SK7682001A3/sk unknown
- 1999-12-06 ID IDW00200101231A patent/ID30158A/id unknown
- 1999-12-06 CA CA002350767A patent/CA2350767A1/en not_active Abandoned
- 1999-12-06 CN CN99815997A patent/CN1348446A/zh active Pending
- 1999-12-06 IL IL14318299A patent/IL143182A0/xx unknown
- 1999-12-06 CZ CZ20011956A patent/CZ20011956A3/cs unknown
- 1999-12-06 AU AU19347/00A patent/AU1934700A/en not_active Abandoned
- 1999-12-06 BR BR9916046-3A patent/BR9916046A/pt not_active Application Discontinuation
- 1999-12-06 HU HU0200232A patent/HUP0200232A2/hu unknown
- 1999-12-06 EP EP99963023A patent/EP1144397A3/en not_active Withdrawn
-
2001
- 2001-05-28 ZA ZA200104377A patent/ZA200104377B/en unknown
- 2001-06-08 NO NO20012832A patent/NO20012832L/no not_active Application Discontinuation
- 2001-06-08 BG BG105581A patent/BG105581A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1144397A2 (en) | 2001-10-17 |
| HUP0200232A2 (hu) | 2002-05-29 |
| WO2000034258A3 (en) | 2001-11-29 |
| WO2000034258A2 (en) | 2000-06-15 |
| PL349217A1 (en) | 2002-07-01 |
| CA2350767A1 (en) | 2000-06-15 |
| CZ20011956A3 (cs) | 2001-10-17 |
| JP2002531554A (ja) | 2002-09-24 |
| EP1144397A3 (en) | 2002-09-11 |
| NO20012832D0 (no) | 2001-06-08 |
| BG105581A (en) | 2001-12-31 |
| SK7682001A3 (en) | 2002-07-02 |
| ZA200104377B (en) | 2002-12-20 |
| ID30158A (id) | 2001-11-08 |
| NO20012832L (no) | 2001-08-07 |
| EA200100631A1 (ru) | 2002-02-28 |
| BR9916046A (pt) | 2001-10-02 |
| AU1934700A (en) | 2000-06-26 |
| CN1348446A (zh) | 2002-05-08 |
| TR200101664T2 (tr) | 2002-03-21 |
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