IL142869A0 - Transport vectors - Google Patents

Transport vectors

Info

Publication number
IL142869A0
IL142869A0 IL14286999A IL14286999A IL142869A0 IL 142869 A0 IL142869 A0 IL 142869A0 IL 14286999 A IL14286999 A IL 14286999A IL 14286999 A IL14286999 A IL 14286999A IL 142869 A0 IL142869 A0 IL 142869A0
Authority
IL
Israel
Prior art keywords
transport vectors
truncated forms
vectors
transport
modified
Prior art date
Application number
IL14286999A
Other languages
English (en)
Original Assignee
Cyclacel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9825001.2A external-priority patent/GB9825001D0/en
Priority claimed from GBGB9825000.4A external-priority patent/GB9825000D0/en
Priority claimed from GBGB9902525.6A external-priority patent/GB9902525D0/en
Priority claimed from GBGB9902522.3A external-priority patent/GB9902522D0/en
Priority claimed from GBGB9914578.1A external-priority patent/GB9914578D0/en
Application filed by Cyclacel Ltd filed Critical Cyclacel Ltd
Publication of IL142869A0 publication Critical patent/IL142869A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • C07K14/43581—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies from Drosophila

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Surgical Instruments (AREA)
  • Structure Of Belt Conveyors (AREA)
  • Details Of Aerials (AREA)
  • Medicinal Preparation (AREA)
  • Aerials With Secondary Devices (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL14286999A 1998-11-13 1999-11-11 Transport vectors IL142869A0 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB9825001.2A GB9825001D0 (en) 1998-11-13 1998-11-13 A delivery vector
GBGB9825000.4A GB9825000D0 (en) 1998-11-13 1998-11-13 A delivery vector
GBGB9902525.6A GB9902525D0 (en) 1999-02-04 1999-02-04 Translocation vectors
GBGB9902522.3A GB9902522D0 (en) 1999-02-04 1999-02-04 Truncated vectors
GBGB9914578.1A GB9914578D0 (en) 1999-06-22 1999-06-22 Truncated vetors
PCT/GB1999/003750 WO2000029427A2 (fr) 1998-11-13 1999-11-11 Vecteurs de transport

Publications (1)

Publication Number Publication Date
IL142869A0 true IL142869A0 (en) 2002-03-10

Family

ID=27517480

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14286999A IL142869A0 (en) 1998-11-13 1999-11-11 Transport vectors

Country Status (13)

Country Link
US (2) US7153931B1 (fr)
EP (2) EP1958961A3 (fr)
JP (1) JP2002530059A (fr)
AT (1) ATE419273T1 (fr)
AU (1) AU766489B2 (fr)
CA (1) CA2350919A1 (fr)
CZ (1) CZ20011671A3 (fr)
DE (1) DE69940215D1 (fr)
ES (1) ES2318906T3 (fr)
GB (1) GB2346616B (fr)
HU (1) HUP0204199A3 (fr)
IL (1) IL142869A0 (fr)
WO (1) WO2000029427A2 (fr)

Families Citing this family (51)

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FR2786397B1 (fr) * 1998-11-30 2003-01-10 Synt Em Vecteurs peptidiques de substances a travers la barriere hematoencephalique pour etre utilises dans le diagnostic ou la therapie d'une affection du snc
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
US6864355B1 (en) 2000-05-02 2005-03-08 Yale University Inhibition of NF-κB activation by blockade of IKKβ-NEMO interactions at the NEMO binding domain
US8128922B2 (en) * 1999-10-20 2012-03-06 Johns Hopkins University Superior molecular vaccine linking the translocation domain of a bacterial toxin to an antigen
US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
GB0012528D0 (en) * 2000-05-23 2000-07-12 Univ Palackeho Triterpenoid derivatives
DE10027777A1 (de) * 2000-06-07 2001-12-13 Otogene Ag Transfektionsverfahren
FR2816845B1 (fr) * 2000-11-20 2006-10-20 Centre Nat Rech Scient Vecteurs de transport a travers un epithelium a jonctions serrees
JP2004534049A (ja) * 2001-06-07 2004-11-11 スキンメディカ，インコーポレーテッド 条件細胞培養培地とその用途
DE10128832A1 (de) * 2001-06-15 2003-02-06 Jochen Reis Vektor und dessen Verwendung in gentherapeutischen Verfahren
US20030083262A1 (en) * 2001-08-30 2003-05-01 Praecis Pharmaceuticals Inc. Methods and compositions for treating inflammatory disorders
EP1476176A4 (fr) * 2002-01-30 2006-02-22 Univ Yale Peptides de transport et leurs utilisations
EP1495124A2 (fr) * 2002-04-17 2005-01-12 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Peptides-smac comme agents therapeutiques contre le cancer et les maladies auto-immunes
EP1354952A1 (fr) * 2002-04-17 2003-10-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Peptides dérivés de Smac, comme agents thérapeutiques contre le cancer et les maladies autoimmunes
EP1354953A1 (fr) * 2002-04-17 2003-10-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Peptides dérivés de Smac, comme agents thérapeutoques contre le cancer et les maladies auto-immunes
US20060178297A1 (en) * 2003-01-28 2006-08-10 Troy Carol M Systems and methods for silencing expression of a gene in a cell and uses thereof
CA2814774C (fr) 2003-01-31 2016-03-22 Mount Sinai School Of Medicine Of New York University Therapie combinee destinee au traitement de troubles associes a une carence proteique
WO2004076634A2 (fr) 2003-02-24 2004-09-10 Ira Sanders Translocation par membrane cellulaire d'inhibiteurs snare régulés, compositions associées et procédés de traitement de pathologies
CA2522460A1 (fr) * 2003-04-30 2004-11-11 Applied Research Systems Ars Holding N.V. Inhibiteurs de beta-amyloide et leur utilisation
US9701725B2 (en) 2003-05-05 2017-07-11 The Johns Hopkins University Anti-cancer DNA vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein
GB0311576D0 (en) * 2003-05-20 2003-06-25 Inst Of Ophthalomology Anti-inflammatory agents
US7737250B2 (en) 2003-06-19 2010-06-15 Mount Sinai School Of Medicine Of New York University Peptides for treating axonal damage, inhibition of neurotransmitter release and pain transmission, and blocking calcium influx in neurons
US7342114B2 (en) 2003-07-01 2008-03-11 California Pacific Medical Center Podophyllotoxin derivatives
CA2539132A1 (fr) * 2003-09-16 2005-03-24 Garvan Institute Of Medical Research Methodes pour identifier des composes modulant la proteine kinase c-epsilon (pkc-epsilon) et methode pour traiter un metabolisme aberrant du glucose associe a cette enzyme
US20050148534A1 (en) * 2003-09-22 2005-07-07 Castellino Angelo J. Small molecule compositions and methods for increasing drug efficiency using compositions thereof
WO2006049442A1 (fr) * 2004-11-03 2006-05-11 Forhumantech. Co., Ltd. Compositions pharmaceutiques destinees a etre administrees par voie transdermique
GB0803352D0 (en) 2008-02-22 2008-04-02 Ntnu Technology Transfer As Oligopeptidic compounds and uses thereof
EP2253326B1 (fr) 2008-02-28 2018-04-04 Toray Industries, Inc. Composition pharmaceutique pour une administration transnasale
WO2009147368A1 (fr) * 2008-06-04 2009-12-10 Medical Research Council Peptides
WO2010033240A2 (fr) 2008-09-19 2010-03-25 Nektar Therapeutics Polymères à base de glucide pour administration de médicaments et leurs conjugués
FR2941230B1 (fr) 2009-01-19 2011-03-18 Centre Nat Rech Scient Polypeptides d'adressage specifique a des cellules-cibles d'otx2
US20120165265A1 (en) * 2009-02-26 2012-06-28 Dolmetsch Ricardo E Calcium Signaling Modulators Involving STIM and ORAI Proteins
EP2433953B1 (fr) * 2009-05-20 2015-07-08 Toray Industries, Inc. Peptides à perméabilité membranaire cellulaire
WO2010135704A2 (fr) * 2009-05-22 2010-11-25 Institute For Systems Biology Protéines bactériennes associées à des sécrétions pour stimuler nlrc4
GB201001602D0 (en) 2010-02-01 2010-03-17 Cytovation As Oligopeptidic compounds and uses therof
JP5757497B2 (ja) * 2010-10-06 2015-07-29 公立大学法人大阪府立大学 シガトキシン類ｃｔｘ１ｂおよび５４−デオキシ−ｃｔｘ１ｂを認識するモノクローナル抗体およびそれを用いるシガトキシン類検出キット
AU2012249474A1 (en) * 2011-04-28 2013-11-07 Stc.Unm Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery and methods of using same
US9302014B2 (en) 2011-08-30 2016-04-05 Medical Research Council Cell-penetrating peptides having a central hydrophobic domain
GB201318954D0 (en) 2013-10-28 2013-12-11 Cupid Peptide Company Ltd Cell transport
GB201507722D0 (en) 2015-05-06 2015-06-17 Norwegian Univ Sci & Tech Ntnu Anti-bacterial agents and their use in therapy
WO2017074325A1 (fr) 2015-10-27 2017-05-04 California Pacific Medical Center Dérivés de podophyllotoxine et leur utilisation
US10087194B2 (en) 2015-10-27 2018-10-02 California Pacific Medical Center Podophyllotoxin derivatives and their use
US11672866B2 (en) 2016-01-08 2023-06-13 Paul N. DURFEE Osteotropic nanoparticles for prevention or treatment of bone metastases
WO2018029256A1 (fr) 2016-08-09 2018-02-15 Aarhus Universitet Modulation d'ifi16 et de l'activité sting
WO2018045155A1 (fr) * 2016-09-02 2018-03-08 The Board Of Trustees Of The University Of Illinois Peptide dérivé de kif13b et procédé d'inhibition de l'angiogenèse
US11344629B2 (en) 2017-03-01 2022-05-31 Charles Jeffrey Brinker Active targeting of cells by monosized protocells
CN111201247A (zh) 2017-04-28 2020-05-26 奥克兰联合服务有限公司 治疗方法和新颖构建体
WO2020066343A1 (fr) 2018-09-26 2020-04-02 株式会社カネカ Peptide de pénétration cellulaire
GB201915454D0 (en) 2019-10-24 2019-12-11 Norwegian Univ Sci & Tech Ntnu Antibacterial bone cement and uses thereof
GB202006699D0 (en) 2020-05-06 2020-06-17 Therapim Pty Ltd Dosage regimen
GB202008888D0 (en) 2020-06-11 2020-07-29 Norwegian Univ Of Science And Technology (Ntnu) Peptides for sepsis treatment

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Publication number Priority date Publication date Assignee Title
US4847240A (en) 1978-01-16 1989-07-11 The Trustees Of Boston University Method of effecting cellular uptake of molecules
US5043329A (en) 1987-02-17 1991-08-27 Board Of Regents, University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
DE3836971C1 (fr) 1988-10-31 1990-05-17 Weck, Wolfgang, Dr.Med., 6990 Bad Mergentheim, De
FR2662698A1 (fr) 1990-06-05 1991-12-06 Centre Nat Rech Scient Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite.
US5888762A (en) 1990-06-05 1999-03-30 Centre National De La Recherche Scientifique (Cnrs) Neurotropic growth factors comprising a homeobox peptide
EP0481930B1 (fr) 1990-10-15 1997-06-18 Tecnogen S.C.P.A. Peptides non-linéaires complémentaires hydropathiquement à des séquences connues d'acides aminés, leur préparation et leurs applications
WO1993022343A1 (fr) 1992-05-01 1993-11-11 The Rockfeller University Systeme antigenique a plusieurs peptides possedant des proprietes d'adjuvant, vaccins prepares a partir dudit systeme
US5674977A (en) 1993-02-05 1997-10-07 The Ontario Cancer Institute Branched synthetic peptide conjugate
US5807746A (en) * 1994-06-13 1998-09-15 Vanderbilt University Method for importing biologically active molecules into cells
FR2739621B1 (fr) 1995-10-05 1997-12-05 Centre Nat Rech Scient Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives
US5843903A (en) 1995-11-27 1998-12-01 The Administrators Of The Tulane Educational Fund Targeted cytotoxic anthracycline analogs
US6344436B1 (en) * 1996-01-08 2002-02-05 Baylor College Of Medicine Lipophilic peptides for macromolecule delivery
US5877282A (en) * 1996-09-20 1999-03-02 Bristol-Myers Squibb Company Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof
WO1998013059A1 (fr) 1996-09-27 1998-04-02 Bristol-Myers Squibb Company Promedicaments hydrolysables pour la liberation de medicaments anticancereux dans des cellules metastatiques
AU7737196A (en) * 1996-11-14 1998-06-03 Brigham And Women's Hospital Polyphosphoinositide binding peptides for intracellular drug delivery
US5929042A (en) 1997-03-03 1999-07-27 The Trustees Of Columbia University In The City Of New York Antisense compounds which prevent cell death and uses thereof
IT1291649B1 (it) * 1997-04-24 1999-01-19 Intercos Italiana Polveri cosmetiche rivestite con ingredienti naturali
US6635623B1 (en) * 1997-06-13 2003-10-21 Baylor College Of Medicine Lipoproteins as nucleic acid vectors
EP0998577B1 (fr) 1997-07-24 2004-10-27 Perseptive Biosystems, Inc. Conjugues de peptides transporteurs et analogues d'acides nucleiques ainsi que leur utilisation
US20030040038A1 (en) * 1997-08-22 2003-02-27 Steven F. Dowdy Inducible regulatory system and use thereof
GB9718609D0 (en) * 1997-09-02 1997-11-05 Imp College Innovations Ltd Fusion protein
AU763020B2 (en) * 1998-03-06 2003-07-10 Oxford Biomedica (Uk) Limited Enhanced prodrug activation
AU4281999A (en) * 1998-06-10 1999-12-30 Queen's University Of Belfast, The Peptide
GB9812675D0 (en) 1998-06-11 1998-08-12 Univ Edinburgh Peptides
GB9814527D0 (en) * 1998-07-03 1998-09-02 Cyclacel Ltd Delivery system

Also Published As

Publication number Publication date
EP1135410A2 (fr) 2001-09-26
WO2000029427A2 (fr) 2000-05-25
ES2318906T3 (es) 2009-05-01
US7153931B1 (en) 2006-12-26
GB2346616A (en) 2000-08-16
GB2346616B (en) 2004-04-21
CA2350919A1 (fr) 2000-05-25
AU1063000A (en) 2000-06-05
ATE419273T1 (de) 2009-01-15
EP1958961A3 (fr) 2008-09-03
HUP0204199A3 (en) 2005-09-28
HUP0204199A2 (hu) 2003-03-28
EP1135410B1 (fr) 2008-12-31
US20020098236A1 (en) 2002-07-25
GB9926719D0 (en) 2000-01-12
WO2000029427A3 (fr) 2000-10-05
DE69940215D1 (de) 2009-02-12
US7101967B2 (en) 2006-09-05
AU766489B2 (en) 2003-10-16
EP1958961A2 (fr) 2008-08-20
JP2002530059A (ja) 2002-09-17
CZ20011671A3 (cs) 2001-10-17

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