IL142869A0 - Transport vectors - Google Patents

Transport vectors

Info

Publication number
IL142869A0
IL142869A0 IL14286999A IL14286999A IL142869A0 IL 142869 A0 IL142869 A0 IL 142869A0 IL 14286999 A IL14286999 A IL 14286999A IL 14286999 A IL14286999 A IL 14286999A IL 142869 A0 IL142869 A0 IL 142869A0
Authority
IL
Israel
Prior art keywords
transport vectors
truncated forms
vectors
transport
modified
Prior art date
Application number
IL14286999A
Other languages
English (en)
Original Assignee
Cyclacel Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9825001.2A external-priority patent/GB9825001D0/en
Priority claimed from GBGB9825000.4A external-priority patent/GB9825000D0/en
Priority claimed from GBGB9902522.3A external-priority patent/GB9902522D0/en
Priority claimed from GBGB9902525.6A external-priority patent/GB9902525D0/en
Priority claimed from GBGB9914578.1A external-priority patent/GB9914578D0/en
Application filed by Cyclacel Ltd filed Critical Cyclacel Ltd
Publication of IL142869A0 publication Critical patent/IL142869A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • C07K14/43577—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies
    • C07K14/43581—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from flies from Drosophila

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Structure Of Belt Conveyors (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Surgical Instruments (AREA)
  • Details Of Aerials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Aerials With Secondary Devices (AREA)
  • Medicinal Preparation (AREA)
IL14286999A 1998-11-13 1999-11-11 Transport vectors IL142869A0 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB9825001.2A GB9825001D0 (en) 1998-11-13 1998-11-13 A delivery vector
GBGB9825000.4A GB9825000D0 (en) 1998-11-13 1998-11-13 A delivery vector
GBGB9902522.3A GB9902522D0 (en) 1999-02-04 1999-02-04 Truncated vectors
GBGB9902525.6A GB9902525D0 (en) 1999-02-04 1999-02-04 Translocation vectors
GBGB9914578.1A GB9914578D0 (en) 1999-06-22 1999-06-22 Truncated vetors
PCT/GB1999/003750 WO2000029427A2 (en) 1998-11-13 1999-11-11 Antennapedia homeodomain helix 3 derived translocation vectors

Publications (1)

Publication Number Publication Date
IL142869A0 true IL142869A0 (en) 2002-03-10

Family

ID=27517480

Family Applications (1)

Application Number Title Priority Date Filing Date
IL14286999A IL142869A0 (en) 1998-11-13 1999-11-11 Transport vectors

Country Status (13)

Country Link
US (2) US7153931B1 (xx)
EP (2) EP1135410B1 (xx)
JP (1) JP2002530059A (xx)
AT (1) ATE419273T1 (xx)
AU (1) AU766489B2 (xx)
CA (1) CA2350919A1 (xx)
CZ (1) CZ20011671A3 (xx)
DE (1) DE69940215D1 (xx)
ES (1) ES2318906T3 (xx)
GB (1) GB2346616B (xx)
HU (1) HUP0204199A3 (xx)
IL (1) IL142869A0 (xx)
WO (1) WO2000029427A2 (xx)

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FR2786397B1 (fr) * 1998-11-30 2003-01-10 Synt Em Vecteurs peptidiques de substances a travers la barriere hematoencephalique pour etre utilises dans le diagnostic ou la therapie d'une affection du snc
US6372494B1 (en) 1999-05-14 2002-04-16 Advanced Tissue Sciences, Inc. Methods of making conditioned cell culture medium compositions
US6864355B1 (en) 2000-05-02 2005-03-08 Yale University Inhibition of NF-κB activation by blockade of IKKβ-NEMO interactions at the NEMO binding domain
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US7049395B2 (en) 2000-05-02 2006-05-23 Yale University Anti-inflammatory compounds and uses thereof
GB0012528D0 (en) * 2000-05-23 2000-07-12 Univ Palackeho Triterpenoid derivatives
DE10027777A1 (de) * 2000-06-07 2001-12-13 Otogene Ag Transfektionsverfahren
FR2816845B1 (fr) * 2000-11-20 2006-10-20 Centre Nat Rech Scient Vecteurs de transport a travers un epithelium a jonctions serrees
EP1406573A4 (en) * 2001-06-07 2005-03-30 Skinmedica Inc CONDITIONED CELL CULTURE MEDIA AND ITS USES
DE10128832A1 (de) * 2001-06-15 2003-02-06 Jochen Reis Vektor und dessen Verwendung in gentherapeutischen Verfahren
JP2005525998A (ja) * 2001-08-30 2005-09-02 プラエシス ファーマシューティカルズ インコーポレーテッド 炎症性疾患の治療のための方法および組成物
WO2003064614A2 (en) * 2002-01-30 2003-08-07 Yale University Transport peptides and uses therefor
EP1495124A2 (en) * 2002-04-17 2005-01-12 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
EP1354952A1 (en) * 2002-04-17 2003-10-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
EP1354953A1 (en) * 2002-04-17 2003-10-22 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Smac-peptides as therapeutics against cancer and autoimmune diseases
US20060178297A1 (en) * 2003-01-28 2006-08-10 Troy Carol M Systems and methods for silencing expression of a gene in a cell and uses thereof
CA2814774C (en) 2003-01-31 2016-03-22 Mount Sinai School Of Medicine Of New York University Combination therapy for treating protein deficiency disorders
US20060153876A1 (en) 2003-02-24 2006-07-13 Ira Sanders Cell membrane translocation of regulated snare inhibitors, compositions therefor, and methods for treatment of disease
EP1618129A2 (en) * 2003-04-30 2006-01-25 Applied Research Systems ARS Holding N.V. Beta-amyloid inhibitors and use thereof
WO2004098526A2 (en) 2003-05-05 2004-11-18 Johns Hopkins University Anti-cancer dna vaccine employing plasmids encoding signal sequence, mutant oncoprotein antigen, and heat shock protein
GB0311576D0 (en) * 2003-05-20 2003-06-25 Inst Of Ophthalomology Anti-inflammatory agents
WO2004112728A2 (en) 2003-06-19 2004-12-29 Mount Sinai School Of Medicine Of New York University Methods and agents for treating axonal damage, inhibition of neurotransmitter release and pain transmission, and blocking calcium influx in neurons
US7342114B2 (en) 2003-07-01 2008-03-11 California Pacific Medical Center Podophyllotoxin derivatives
EP2228069A1 (en) * 2003-09-16 2010-09-15 Garvan Institute Of Medical Research Antagonists of protein kinase c-epsilon (pkcepsilon) and their use for the treatment of aberrant glucose metabolism associated therewith.
US20050148534A1 (en) * 2003-09-22 2005-07-07 Castellino Angelo J. Small molecule compositions and methods for increasing drug efficiency using compositions thereof
WO2006049442A1 (en) * 2004-11-03 2006-05-11 Forhumantech. Co., Ltd. Pharmaceutical compositions for transdermal delivery
GB0803352D0 (en) 2008-02-22 2008-04-02 Ntnu Technology Transfer As Oligopeptidic compounds and uses thereof
RU2470666C2 (ru) 2008-02-28 2012-12-27 Торэй Индастриз, Инк. Фармацевтическая композиция для трансназального введения
EP2283029A1 (en) * 2008-06-04 2011-02-16 Medical Research Council Peptides
WO2010033207A1 (en) 2008-09-19 2010-03-25 Nektar Therapeutics Polymer conjugates of therapeutic peptides
FR2941230B1 (fr) 2009-01-19 2011-03-18 Centre Nat Rech Scient Polypeptides d'adressage specifique a des cellules-cibles d'otx2
US20120165265A1 (en) * 2009-02-26 2012-06-28 Dolmetsch Ricardo E Calcium Signaling Modulators Involving STIM and ORAI Proteins
CN102428096B (zh) * 2009-05-20 2015-03-25 东丽株式会社 细胞膜通透性肽
EP2432501B1 (en) * 2009-05-22 2016-12-14 The Institute for Systems Biology Secretion-related bacterial proteins for nlrc4 stimulation
GB201001602D0 (en) 2010-02-01 2010-03-17 Cytovation As Oligopeptidic compounds and uses therof
JP5757497B2 (ja) * 2010-10-06 2015-07-29 公立大学法人大阪府立大学 シガトキシン類ｃｔｘ１ｂおよび５４−デオキシ−ｃｔｘ１ｂを認識するモノクローナル抗体およびそれを用いるシガトキシン類検出キット
WO2012149376A2 (en) 2011-04-28 2012-11-01 Stc.Unm Porous nanoparticle-supported lipid bilayers (protocells) for targeted delivery and methods of using same
AU2012300633B2 (en) 2011-08-30 2017-04-27 United Kingdom Research And Innovation Cell- penetrating peptides having a central hydrophobic domain
GB201318954D0 (en) 2013-10-28 2013-12-11 Cupid Peptide Company Ltd Cell transport
GB201507722D0 (en) 2015-05-06 2015-06-17 Norwegian Univ Sci & Tech Ntnu Anti-bacterial agents and their use in therapy
US10087194B2 (en) 2015-10-27 2018-10-02 California Pacific Medical Center Podophyllotoxin derivatives and their use
JP6550538B2 (ja) 2015-10-27 2019-07-24 カリフォルニア パシフィック メディカル センター ポドフィロトキシン誘導体およびそれらの使用
WO2017120504A1 (en) 2016-01-08 2017-07-13 Durfee Paul N Osteotropic nanoparticles for prevention or treatment of bone metastases
US11725035B2 (en) 2016-08-09 2023-08-15 Stipe Therapeutics Aps Methods of treating a disorder associated with with insufficient stimulator of interferon genes (STING) activity
AU2017318610B2 (en) * 2016-09-02 2021-12-09 The Board Of Trustees Of The University Of Illinois KIF13B-derived peptide and method of inhibiting Angiogenesis
US11344629B2 (en) 2017-03-01 2022-05-31 Charles Jeffrey Brinker Active targeting of cells by monosized protocells
EP3615575A4 (en) 2017-04-28 2021-01-13 Auckland Uniservices Limited METHOD FOR TREATMENT OF NEW CONSTRUCTIONS
KR20210064254A (ko) 2018-09-26 2021-06-02 가부시키가이샤 가네카 세포막 투과성 펩티드
GB201915454D0 (en) 2019-10-24 2019-12-11 Norwegian Univ Sci & Tech Ntnu Antibacterial bone cement and uses thereof
GB202006699D0 (en) 2020-05-06 2020-06-17 Therapim Pty Ltd Dosage regimen
GB202008888D0 (en) 2020-06-11 2020-07-29 Norwegian Univ Of Science And Technology (Ntnu) Peptides for sepsis treatment

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US4847240A (en) 1978-01-16 1989-07-11 The Trustees Of Boston University Method of effecting cellular uptake of molecules
US5043329A (en) 1987-02-17 1991-08-27 Board Of Regents, University Of Texas System Methods and compositions employing unique mixtures of polar and neutral lipids for protecting the gastrointestinal tract
DE3836971C1 (xx) 1988-10-31 1990-05-17 Weck, Wolfgang, Dr.Med., 6990 Bad Mergentheim, De
US5888762A (en) 1990-06-05 1999-03-30 Centre National De La Recherche Scientifique (Cnrs) Neurotropic growth factors comprising a homeobox peptide
FR2662698A1 (fr) 1990-06-05 1991-12-06 Centre Nat Rech Scient Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite.
DE69132567D1 (de) 1990-10-15 2001-05-03 Tecnogen Scpa Verfahren zur Feststellung von proteolitischen Wirkungen und/oder deren Inhibitoren
US5580563A (en) 1992-05-01 1996-12-03 Tam; James P. Multiple antigen peptide system having adjuvant properties, vaccines prepared therefrom and methods of use thereof
US5674977A (en) 1993-02-05 1997-10-07 The Ontario Cancer Institute Branched synthetic peptide conjugate
US5807746A (en) * 1994-06-13 1998-09-15 Vanderbilt University Method for importing biologically active molecules into cells
FR2739621B1 (fr) * 1995-10-05 1997-12-05 Centre Nat Rech Scient Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives
US5843903A (en) 1995-11-27 1998-12-01 The Administrators Of The Tulane Educational Fund Targeted cytotoxic anthracycline analogs
US6344436B1 (en) * 1996-01-08 2002-02-05 Baylor College Of Medicine Lipophilic peptides for macromolecule delivery
US5877282A (en) * 1996-09-20 1999-03-02 Bristol-Myers Squibb Company Peptide inhibitors of nuclear protein translocation having nuclear localization sequences and methods of use thereof
AU739028B2 (en) 1996-09-27 2001-10-04 Bristol-Myers Squibb Company Hydrolyzable prodrugs for delivery of anticancer drugs to metastatic cells
AU7737196A (en) * 1996-11-14 1998-06-03 Brigham And Women's Hospital Polyphosphoinositide binding peptides for intracellular drug delivery
US5929042A (en) 1997-03-03 1999-07-27 The Trustees Of Columbia University In The City Of New York Antisense compounds which prevent cell death and uses thereof
IT1291649B1 (it) * 1997-04-24 1999-01-19 Intercos Italiana Polveri cosmetiche rivestite con ingredienti naturali
US6635623B1 (en) * 1997-06-13 2003-10-21 Baylor College Of Medicine Lipoproteins as nucleic acid vectors
DE69827260T2 (de) * 1997-07-24 2006-02-16 PerSeptive Biosystems, Inc., Framingham Konjugate von transportpeptiden und nukleinsäureanaloga und deren verwendung
WO1999010376A1 (en) * 1997-08-22 1999-03-04 Washington University Inducible regulatory system and use thereof
GB9718609D0 (en) * 1997-09-02 1997-11-05 Imp College Innovations Ltd Fusion protein
AU763020B2 (en) * 1998-03-06 2003-07-10 Oxford Biomedica (Uk) Limited Enhanced prodrug activation
AU4281999A (en) * 1998-06-10 1999-12-30 Queen's University Of Belfast, The Peptide
GB9812675D0 (en) 1998-06-11 1998-08-12 Univ Edinburgh Peptides
GB9814527D0 (en) 1998-07-03 1998-09-02 Cyclacel Ltd Delivery system

Also Published As

Publication number Publication date
EP1958961A2 (en) 2008-08-20
US7153931B1 (en) 2006-12-26
EP1135410A2 (en) 2001-09-26
AU1063000A (en) 2000-06-05
CZ20011671A3 (cs) 2001-10-17
ES2318906T3 (es) 2009-05-01
CA2350919A1 (en) 2000-05-25
JP2002530059A (ja) 2002-09-17
DE69940215D1 (de) 2009-02-12
ATE419273T1 (de) 2009-01-15
EP1135410B1 (en) 2008-12-31
EP1958961A3 (en) 2008-09-03
GB9926719D0 (en) 2000-01-12
GB2346616B (en) 2004-04-21
US20020098236A1 (en) 2002-07-25
GB2346616A (en) 2000-08-16
HUP0204199A3 (en) 2005-09-28
WO2000029427A2 (en) 2000-05-25
AU766489B2 (en) 2003-10-16
HUP0204199A2 (hu) 2003-03-28
US7101967B2 (en) 2006-09-05
WO2000029427A3 (en) 2000-10-05

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