IL137685A0 - Processes and intermediates useful to make antifolates - Google Patents
Processes and intermediates useful to make antifolatesInfo
- Publication number
- IL137685A0 IL137685A0 IL13768599A IL13768599A IL137685A0 IL 137685 A0 IL137685 A0 IL 137685A0 IL 13768599 A IL13768599 A IL 13768599A IL 13768599 A IL13768599 A IL 13768599A IL 137685 A0 IL137685 A0 IL 137685A0
- Authority
- IL
- Israel
- Prior art keywords
- processes
- intermediates useful
- antifolates
- make
- make antifolates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Steroid Compounds (AREA)
- Furan Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7432798P | 1998-02-11 | 1998-02-11 | |
| PCT/US1999/001689 WO1999041230A1 (en) | 1998-02-11 | 1999-01-27 | Processes and intermediates useful to make antifolates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL137685A0 true IL137685A0 (en) | 2001-10-31 |
Family
ID=22118973
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13768599A IL137685A0 (en) | 1998-02-11 | 1999-01-27 | Processes and intermediates useful to make antifolates |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US6426417B1 (zh) |
| EP (1) | EP1054859A4 (zh) |
| JP (1) | JP2002503648A (zh) |
| KR (1) | KR20010040836A (zh) |
| CN (1) | CN1290247A (zh) |
| AR (1) | AR018538A1 (zh) |
| AU (1) | AU739292B2 (zh) |
| BR (1) | BR9907876A (zh) |
| CA (1) | CA2319424A1 (zh) |
| EA (1) | EA002723B1 (zh) |
| HR (1) | HRP20000537A2 (zh) |
| HU (1) | HUP0100869A3 (zh) |
| IL (1) | IL137685A0 (zh) |
| NO (1) | NO20004026L (zh) |
| NZ (1) | NZ505406A (zh) |
| PL (1) | PL342161A1 (zh) |
| TR (1) | TR200002352T2 (zh) |
| WO (1) | WO1999041230A1 (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2270030E (pt) * | 2000-02-28 | 2012-07-24 | Novartis Vaccines & Diagnostic | Expressão heteróloga de proteínas de neisseria |
| KR101686179B1 (ko) | 2015-02-05 | 2016-12-28 | 이삼구 | 산화질소를 생성하는 아르기닌 함유가 증진된 귀뚜라미 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS51113874A (en) | 1975-04-01 | 1976-10-07 | Yamanouchi Pharmaceut Co Ltd | Method for synthesizing 4-hydroxynicotinic acid or its lower alkyl est ers |
| JPS55730A (en) | 1978-06-20 | 1980-01-07 | Toyo Soda Mfg Co Ltd | 5-h-pyrido 1',2':1,2-pyrimido 4, 5-b acridine 7, 15-dione and its preparation |
| US4927828A (en) * | 1985-03-08 | 1990-05-22 | The Trustees Of Princeton University | Diastereoisomeric tetrahydropyrido-(2,3,d) pyrimidine derivatives |
| NZ219971A (en) * | 1986-06-06 | 1989-08-29 | Univ Princeton | Tetrahydropyrido (2,3-d pyrimidine derivatives and pharmaceutical compositions |
| US4895946A (en) * | 1987-10-26 | 1990-01-23 | The Trustees Of Princeton University | Process for the preparation of fused pyridine compounds |
| DK172753B1 (da) * | 1988-05-25 | 1999-06-28 | Lilly Co Eli | N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat |
| KR0162654B1 (ko) | 1989-12-11 | 1998-11-16 | 알렌 제이. 시니스갤리 | N-(피롤로[2,3-d]피리미딘-3-일아크릴)-글루타민산 유도체 |
| US5248775A (en) | 1989-12-11 | 1993-09-28 | The Trustees Of Princeton University | Pyrrolo(2,3-d)pyrimidines |
| US4996206A (en) | 1989-12-11 | 1991-02-26 | The Trustees Of Princeton University | N-(pyrrolo[2,3-d]pyrimidin-3-ylacyl)-glutamic acid derivatives |
| US5536724A (en) | 1992-03-03 | 1996-07-16 | Sri International | Antiinflammatory and antineoplastic 5-deazaaminopterins and 5,10-dideazaaminopterins |
-
1999
- 1999-01-27 TR TR2000/02352T patent/TR200002352T2/xx unknown
- 1999-01-27 EP EP99903432A patent/EP1054859A4/en not_active Withdrawn
- 1999-01-27 CN CN99802883A patent/CN1290247A/zh active Pending
- 1999-01-27 PL PL99342161A patent/PL342161A1/xx unknown
- 1999-01-27 JP JP2000531425A patent/JP2002503648A/ja not_active Withdrawn
- 1999-01-27 EA EA200000829A patent/EA002723B1/ru not_active IP Right Cessation
- 1999-01-27 KR KR1020007008731A patent/KR20010040836A/ko not_active Application Discontinuation
- 1999-01-27 CA CA002319424A patent/CA2319424A1/en not_active Abandoned
- 1999-01-27 AU AU23452/99A patent/AU739292B2/en not_active Ceased
- 1999-01-27 BR BR9907876-7A patent/BR9907876A/pt not_active IP Right Cessation
- 1999-01-27 IL IL13768599A patent/IL137685A0/xx unknown
- 1999-01-27 WO PCT/US1999/001689 patent/WO1999041230A1/en not_active Application Discontinuation
- 1999-01-27 NZ NZ505406A patent/NZ505406A/xx unknown
- 1999-01-27 HU HU0100869A patent/HUP0100869A3/hu unknown
- 1999-01-27 US US09/601,707 patent/US6426417B1/en not_active Expired - Fee Related
- 1999-01-29 AR ARP990100384A patent/AR018538A1/es unknown
-
2000
- 2000-08-10 NO NO20004026A patent/NO20004026L/no not_active Application Discontinuation
- 2000-08-11 HR HR20000537A patent/HRP20000537A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2345299A (en) | 1999-08-30 |
| EP1054859A1 (en) | 2000-11-29 |
| KR20010040836A (ko) | 2001-05-15 |
| WO1999041230A1 (en) | 1999-08-19 |
| HUP0100869A3 (en) | 2002-12-28 |
| AU739292B2 (en) | 2001-10-11 |
| HUP0100869A2 (hu) | 2001-08-28 |
| TR200002352T2 (tr) | 2000-12-21 |
| PL342161A1 (en) | 2001-05-21 |
| EA200000829A1 (ru) | 2001-02-26 |
| NO20004026D0 (no) | 2000-08-10 |
| EP1054859A4 (en) | 2003-03-05 |
| BR9907876A (pt) | 2000-10-31 |
| AR018538A1 (es) | 2001-11-28 |
| CN1290247A (zh) | 2001-04-04 |
| US6426417B1 (en) | 2002-07-30 |
| CA2319424A1 (en) | 1999-08-19 |
| JP2002503648A (ja) | 2002-02-05 |
| HRP20000537A2 (en) | 2000-10-31 |
| EA002723B1 (ru) | 2002-08-29 |
| NO20004026L (no) | 2000-10-04 |
| NZ505406A (en) | 2003-01-31 |
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