IL137649A - Method of adsorption chromatography - Google Patents
Method of adsorption chromatographyInfo
- Publication number
- IL137649A IL137649A IL13764998A IL13764998A IL137649A IL 137649 A IL137649 A IL 137649A IL 13764998 A IL13764998 A IL 13764998A IL 13764998 A IL13764998 A IL 13764998A IL 137649 A IL137649 A IL 137649A
- Authority
- IL
- Israel
- Prior art keywords
- liquid
- density
- approximately
- column
- sample molecule
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/265—Adsorption chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2215/00—Separating processes involving the treatment of liquids with adsorbents
- B01D2215/02—Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
- B01D2215/021—Physically moving or fluidising the adsorbent beads or particles or slurry, excluding the movement of the entire columns
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Peptides Or Proteins (AREA)
- Liquid Developers In Electrophotography (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7520298P | 1998-02-18 | 1998-02-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL137649A true IL137649A (en) | 2004-08-31 |
Family
ID=22124214
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13764998A IL137649A (en) | 1998-02-18 | 1998-02-18 | Method of adsorption chromatography |
IL13764999A IL137649A0 (en) | 1998-02-18 | 1999-02-16 | Adsorption chromatography |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13764999A IL137649A0 (en) | 1998-02-18 | 1999-02-16 | Adsorption chromatography |
Country Status (10)
Country | Link |
---|---|
US (1) | US6027650A (de) |
EP (1) | EP1064066B1 (de) |
JP (1) | JP2002503539A (de) |
AT (1) | ATE250966T1 (de) |
AU (1) | AU745806B2 (de) |
CA (1) | CA2322048A1 (de) |
DE (1) | DE69911754T2 (de) |
DK (1) | DK1064066T3 (de) |
IL (2) | IL137649A (de) |
WO (1) | WO1999042193A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU767183B2 (en) * | 1998-10-31 | 2003-11-06 | Ge Healthcare Bio-Sciences Ab | A new system and its units |
US6290910B1 (en) * | 1999-03-03 | 2001-09-18 | University Of North Florida | Continuously variable volume chamber for flow injection analysis |
KR100409092B1 (ko) * | 2000-12-22 | 2003-12-11 | 주)녹십자 | 단백질의 제조 방법 |
KR100372931B1 (ko) * | 2000-12-26 | 2003-02-25 | 변유량 | 팽창층 겔 흡착-이온교환 크로마토그래피법을 이용한 박테리오신의 분리 정제 방법 |
US20070199899A1 (en) * | 2004-03-31 | 2007-08-30 | Andrew Alaska | Sweep-flow methods and clogging disrupters, for expanded bed chromatography of liquids with suspended particulates |
PL1765866T3 (pl) * | 2004-06-07 | 2014-06-30 | Therapure Biopharma Inc | Wydzielanie białek osocza lub surowicy |
SE529259C2 (sv) * | 2005-08-31 | 2007-06-12 | Ge Healthcare Bio Sciences Ab | Tillverkning av kromarografimatriser, en kromarografimatris, en vätskekromatografikolonn, prcess för att isolera målföreningar och användning av en kromarografimatris för vätskekromatografi |
US7608187B2 (en) * | 2005-11-21 | 2009-10-27 | Ge Healthcare Bio-Sciences Ab | Manufacture of a chromatography matrix |
EP1972933A1 (de) * | 2007-03-23 | 2008-09-24 | Coöperatie AVEBE U.A. | Chromatographisches Säulesystem |
AU2008231721B8 (en) * | 2007-03-28 | 2013-01-31 | Patheon Holdings I B.V. | Expanded bed column and disposable chromatography |
US9488625B2 (en) | 2010-12-15 | 2016-11-08 | Baxalta GmbH | Purification of factor VIII using a conductivity gradient |
WO2012084828A1 (en) | 2010-12-21 | 2012-06-28 | F. Hoffmann-La Roche Ag | Chromatography equipment characterization |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4411789A (en) * | 1981-08-21 | 1983-10-25 | Liburdy Robert P | Magnetic resonance chromatography |
US4675113A (en) * | 1984-11-28 | 1987-06-23 | University Patents, Inc. | Affinity chromatography using dried calcium alginate-magnetite separation media in a magnetically stabilized fluidized bed |
US5084184A (en) * | 1991-03-11 | 1992-01-28 | Exxon Chemical Patents Inc. | Positive focusing in a magnetically stabilized fluidized bed |
SE9101149D0 (sv) * | 1991-04-17 | 1991-04-17 | Pharmacia Lkb Biotech | Beads for down stream processing |
DE4203268A1 (de) * | 1992-02-05 | 1993-08-12 | Laevosan Gmbh & Co Kg | Verfahren zur chromatographischen trennung |
DE69501817T2 (de) * | 1994-01-18 | 1998-09-10 | Genentech Inc | Verfahren zur behandlung von parasitären infektionen unter verwendung von ige-antagonisten |
JP3780315B2 (ja) * | 1994-03-03 | 2006-05-31 | ジェネンテク・インコーポレイテッド | 炎症性疾患の処置のための抗il−8モノクローナル抗体 |
EP0699687B1 (de) * | 1994-08-31 | 2004-01-28 | Mitsubishi Pharma Corporation | Verfahren zur Reinigung von rekombinantem menschlichem Serumalbumin |
WO1996020798A1 (de) * | 1995-01-04 | 1996-07-11 | Oberburg Engineering Ag | Drehturm mit expandierwerkzeugen |
IL117645A (en) * | 1995-03-30 | 2005-08-31 | Genentech Inc | Vascular endothelial cell growth factor antagonists for use as medicaments in the treatment of age-related macular degeneration |
US6096871A (en) * | 1995-04-14 | 2000-08-01 | Genentech, Inc. | Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life |
-
1998
- 1998-02-18 IL IL13764998A patent/IL137649A/en active IP Right Grant
-
1999
- 1999-02-16 DK DK99934253T patent/DK1064066T3/da active
- 1999-02-16 IL IL13764999A patent/IL137649A0/xx unknown
- 1999-02-16 AT AT99934253T patent/ATE250966T1/de not_active IP Right Cessation
- 1999-02-16 CA CA002322048A patent/CA2322048A1/en not_active Abandoned
- 1999-02-16 WO PCT/US1999/003293 patent/WO1999042193A1/en not_active Application Discontinuation
- 1999-02-16 DE DE69911754T patent/DE69911754T2/de not_active Revoked
- 1999-02-16 US US09/250,976 patent/US6027650A/en not_active Expired - Fee Related
- 1999-02-16 EP EP99934253A patent/EP1064066B1/de not_active Revoked
- 1999-02-16 AU AU32948/99A patent/AU745806B2/en not_active Ceased
- 1999-02-16 JP JP2000532198A patent/JP2002503539A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL137649A0 (en) | 2001-10-31 |
AU745806B2 (en) | 2002-04-11 |
WO1999042193A1 (en) | 1999-08-26 |
DK1064066T3 (da) | 2003-12-15 |
DE69911754D1 (en) | 2003-11-06 |
EP1064066A1 (de) | 2001-01-03 |
DE69911754T2 (de) | 2004-07-29 |
JP2002503539A (ja) | 2002-02-05 |
CA2322048A1 (en) | 1999-08-26 |
EP1064066B1 (de) | 2003-10-01 |
AU3294899A (en) | 1999-09-06 |
ATE250966T1 (de) | 2003-10-15 |
US6027650A (en) | 2000-02-22 |
WO1999042193A9 (en) | 1999-11-11 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Chang et al. | Ion exchange purification of G6PDH from unclarified yeast cell homogenates using expanded bed adsorption | |
Litzen et al. | Separation and quantitation of monoclonal antibody aggregates by asymmetrical flow field-flow fractionation and comparison to gel permeation chromatography | |
KR101484659B1 (ko) | 단백질 정제하는 동안 샘플 중의 하나 이상의 불순물 양을 감소시키는 방법 | |
Thömmes et al. | Isolation of monoclonal antibodies from cell containing hybridoma broth using a protein A coated adsorbent in expanded beds | |
Pungor Jr et al. | Continuous affinity–recycle extraction: a novel protein separation technique | |
JP5148484B2 (ja) | クロマトグラフィーマトリックスの再生 | |
EP1064066B1 (de) | Adsoptionschromatographie | |
EP1775000A2 (de) | Verfahren zum Herstellen von universal verwendbarem Blutplasma aus Blut | |
US20210080434A1 (en) | Chromatography System with Guard Columns | |
US20100130727A1 (en) | Methods and Systems for Isolating Target Molecules from Complex Solutions by Column-Chromatography Using Eluants Containing Organic Solvents | |
EP1154827A1 (de) | Reinigung von biologischen substanzen | |
WO1990005018A1 (en) | Membrane affinity apparatus and purification methods related thereto | |
JP3444900B2 (ja) | 液体クロマトグラフィ及びカラム充填剤 | |
US5466377A (en) | Chromatography media and their uses | |
Paliwal et al. | Automated process monitoring of monoclonal antibody production | |
Li et al. | Expanded bed adsorption/desorption of proteins with Streamline Direct CST I adsorbent | |
KR101365474B1 (ko) | 생체분자의 크로마토그래피 정제 방법을 최적화하는 방법 | |
Bailon et al. | Receptor-affinity chromatography | |
CN114249793A (zh) | 重组蛋白纯化方法 | |
WO1991014706A2 (en) | Lectin affinity membranes and methods for using them | |
Paliwal et al. | [6] Rapid separations of proteins by liquid chromatography | |
CA2363483A1 (en) | Chromatogrpahic separation apparatus and method | |
Chase et al. | On-line monitoring of breakthrough curves within an expanded bed adsorber | |
US20090259028A1 (en) | Prevention of leaching of ligands from affinity-based purification systems | |
WO2024137836A1 (en) | Physical integration device for on-line purification analytics |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed |