ATE245048T1 - Chromatographisches verfahren mit verwendung eines wirbelbetts - Google Patents

Chromatographisches verfahren mit verwendung eines wirbelbetts

Info

Publication number
ATE245048T1
ATE245048T1 AT99958558T AT99958558T ATE245048T1 AT E245048 T1 ATE245048 T1 AT E245048T1 AT 99958558 T AT99958558 T AT 99958558T AT 99958558 T AT99958558 T AT 99958558T AT E245048 T1 ATE245048 T1 AT E245048T1
Authority
AT
Austria
Prior art keywords
vessel
pump
valve
pipes
distributor
Prior art date
Application number
AT99958558T
Other languages
English (en)
Inventor
Patrik Leijon
Original Assignee
Amersham Biosciences Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE9803737A external-priority patent/SE9803737D0/xx
Priority claimed from SE9803813A external-priority patent/SE9803813D0/xx
Application filed by Amersham Biosciences Ab filed Critical Amersham Biosciences Ab
Application granted granted Critical
Publication of ATE245048T1 publication Critical patent/ATE245048T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1807Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B01D15/203Equilibration or regeneration
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2215/00Separating processes involving the treatment of liquids with adsorbents
    • B01D2215/02Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
    • B01D2215/021Physically moving or fluidising the adsorbent beads or particles or slurry, excluding the movement of the entire columns
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/56Packing methods or coating methods
    • G01N2030/562Packing methods or coating methods packing
    • G01N2030/565Packing methods or coating methods packing slurry packing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/50Conditioning of the sorbent material or stationary liquid
    • G01N30/58Conditioning of the sorbent material or stationary liquid the sorbent moving as a whole
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/60Construction of the column
    • G01N30/6004Construction of the column end pieces
    • G01N30/6017Fluid distributors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
AT99958558T 1998-10-31 1999-10-31 Chromatographisches verfahren mit verwendung eines wirbelbetts ATE245048T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9803737A SE9803737D0 (sv) 1998-10-31 1998-10-31 a new system and its units and the use of thereof
SE9803813A SE9803813D0 (sv) 1998-11-08 1998-11-08 A new system, its units and their use in separations
PCT/SE1999/001965 WO2000025884A1 (en) 1998-10-31 1999-10-31 A chromatographic process utilizing a fluidised bed

Publications (1)

Publication Number Publication Date
ATE245048T1 true ATE245048T1 (de) 2003-08-15

Family

ID=26663422

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99958558T ATE245048T1 (de) 1998-10-31 1999-10-31 Chromatographisches verfahren mit verwendung eines wirbelbetts

Country Status (8)

Country Link
US (2) US6610200B1 (de)
EP (2) EP1131146B1 (de)
JP (2) JP2002528256A (de)
AT (1) ATE245048T1 (de)
AU (2) AU768241B2 (de)
CA (2) CA2350690C (de)
DE (1) DE69909644T2 (de)
WO (2) WO2000025883A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5902485A (en) 1994-10-03 1999-05-11 Amersham Pharmacia Biotech Ab Access valve devices, their use in separation apparatus and corresponding methods
US6977046B2 (en) * 2000-05-12 2005-12-20 Upfront Chromatography A/S Bed adsorption system
SE0001859D0 (sv) * 2000-05-17 2000-05-17 Amersham Pharm Biotech Ab Inlet device and its use
DE10029142B4 (de) * 2000-06-14 2004-08-05 InfraServ GmbH & Co. Höchst KG Verfahren zum Entpacken von Chromatographiesäulen und dafür geeignete Vorrichtung
SE0100714D0 (sv) * 2000-07-13 2001-02-28 Ap Biotech Ab Reaction vessel and method for distributing fluid in such a vessel
EP1199099A1 (de) * 2000-10-19 2002-04-24 Amersham Biosciences AB Reaktor
US7943393B2 (en) * 2003-07-14 2011-05-17 Phynexus, Inc. Method and device for extracting an analyte
CN102924565A (zh) 2004-06-07 2013-02-13 厄普弗朗特色谱公司 血浆或者血清蛋白的分离
US7507337B2 (en) * 2004-09-03 2009-03-24 Symyx Technologies, Inc. System and method for rapid chromatography with fluid temperature and mobile phase composition control
ES2616982T3 (es) * 2007-03-28 2017-06-15 Patheon Holdings I B.V. Columna de lecho expandido y cromatografía desechable
WO2010138061A1 (en) * 2009-05-29 2010-12-02 Ge Healthcare Bio-Sciences Ab Fluid distributor unit
JP5737671B2 (ja) * 2010-11-16 2015-06-17 国立大学法人九州工業大学 金属イオン含有排水の処理装置
CN102078706B (zh) * 2010-12-02 2012-12-12 温州市东瓯微孔过滤有限公司 一种离子交换层析过滤方法及其色谱分离层析柱
US10773863B2 (en) 2011-06-22 2020-09-15 Sartorius Stedim North America Inc. Vessel closures and methods for using and manufacturing same
EP2931400B1 (de) * 2012-12-14 2021-07-07 Cytiva BioProcess R&D AB Verfahren zur reinigung von schüttbett-chromatografiesäulen
CN104813155B (zh) 2013-01-31 2019-03-01 Emd密理博公司 一次性直接捕获装置
WO2019099406A1 (en) 2017-11-14 2019-05-23 Sartorius Stedim North America Inc. Fluid transfer assembly with a junction having multiple fluid pathways
US11691866B2 (en) 2017-11-14 2023-07-04 Sartorius Stedim North America Inc. System for simultaneous distribution of fluid to multiple vessels and method of using the same
US11577953B2 (en) 2017-11-14 2023-02-14 Sartorius Stedim North America, Inc. System for simultaneous distribution of fluid to multiple vessels and method of using the same
US11319201B2 (en) 2019-07-23 2022-05-03 Sartorius Stedim North America Inc. System for simultaneous filling of multiple containers

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE278687C (de) *
US4450082A (en) * 1981-06-11 1984-05-22 Asahi Kasei Kogyo Kabushiki Kaisha Method for obtaining uniform stream in adsorption column
FR2575666B1 (fr) 1985-01-04 1989-08-18 Centre Nat Rech Scient Procede et dispositif pour la separation chromatographique de macromolecules biologiques
CA1247329A (en) * 1985-05-06 1988-12-28 Craig J. Brown Fluid treatment process and apparatus
DD278687A3 (de) * 1986-10-27 1990-05-16 Adw Ddr Vorrichtung zur praeparativen fluessigkeits-gegenstromchromatographie
JPS63231262A (ja) * 1987-03-19 1988-09-27 Sekisui Chem Co Ltd カラム内の液組成変更方法およびカラム支持器
US4871463A (en) * 1988-08-23 1989-10-03 Sepratech Vertical reaction vessel
US5409813A (en) * 1993-09-30 1995-04-25 Systemix, Inc. Method for mammalian cell separation from a mixture of cell populations
US5466377A (en) * 1994-01-19 1995-11-14 Grandics; Peter Chromatography media and their uses
SE9400263L (sv) * 1994-01-28 1995-07-29 Pharmacia Biotech Ab Kolonnuppställning
SE9402091D0 (sv) * 1994-06-14 1994-06-14 Pharmacia Biotech Ab Kromatografikolonn
DE19718652C2 (de) * 1996-05-03 2000-07-20 Pfeiffer Wolfdietrich Vorrichtung für die Flüssigkeitschromatographie
SE9700383D0 (sv) * 1997-02-04 1997-02-04 Pharmacia Biotech Ab An adsorption/separation method and a medium for adsorption/separation
IL137649A (en) * 1998-02-18 2004-08-31 Genentech Inc Method of adsorption chromatography

Also Published As

Publication number Publication date
JP2002528737A (ja) 2002-09-03
WO2000025883A1 (en) 2000-05-11
CA2348298A1 (en) 2000-05-11
EP1131147A1 (de) 2001-09-12
EP1131146A1 (de) 2001-09-12
WO2000025884A1 (en) 2000-05-11
DE69909644T2 (de) 2004-06-09
CA2350690A1 (en) 2000-05-11
CA2350690C (en) 2008-07-22
EP1131146B1 (de) 2003-07-16
AU767183B2 (en) 2003-11-06
US6706191B1 (en) 2004-03-16
US6610200B1 (en) 2003-08-26
JP2002528256A (ja) 2002-09-03
AU768241B2 (en) 2003-12-04
JP4458679B2 (ja) 2010-04-28
DE69909644D1 (de) 2003-08-21
AU1589800A (en) 2000-05-22
AU1432400A (en) 2000-05-22

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties