IL137419A0 - Nk cells activating receptors and their therapeutic and diagnostic uses - Google Patents

Nk cells activating receptors and their therapeutic and diagnostic uses

Info

Publication number
IL137419A0
IL137419A0 IL13741900A IL13741900A IL137419A0 IL 137419 A0 IL137419 A0 IL 137419A0 IL 13741900 A IL13741900 A IL 13741900A IL 13741900 A IL13741900 A IL 13741900A IL 137419 A0 IL137419 A0 IL 137419A0
Authority
IL
Israel
Prior art keywords
therapeutic
diagnostic uses
activating receptors
targeting
complex
Prior art date
Application number
IL13741900A
Other languages
English (en)
Original Assignee
Yissum Res Dev Co
B G Negev Technologies And App
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co, B G Negev Technologies And App filed Critical Yissum Res Dev Co
Priority to IL13741900A priority Critical patent/IL137419A0/xx
Priority to IL15370001A priority patent/IL153700A0/xx
Priority to DE60115452T priority patent/DE60115452D1/de
Priority to CA002416733A priority patent/CA2416733A1/fr
Priority to EP01956747A priority patent/EP1301605B1/fr
Priority to PCT/IL2001/000664 priority patent/WO2002008287A2/fr
Priority to AU2001278662A priority patent/AU2001278662B2/en
Priority to JP2002514191A priority patent/JP2004504065A/ja
Priority to US10/333,481 priority patent/US20040072256A1/en
Priority to AU7866201A priority patent/AU7866201A/xx
Priority to AT01956747T priority patent/ATE311464T1/de
Publication of IL137419A0 publication Critical patent/IL137419A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Botany (AREA)
  • Pulmonology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL13741900A 2000-07-20 2000-07-20 Nk cells activating receptors and their therapeutic and diagnostic uses IL137419A0 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IL13741900A IL137419A0 (en) 2000-07-20 2000-07-20 Nk cells activating receptors and their therapeutic and diagnostic uses
IL15370001A IL153700A0 (en) 2000-07-20 2001-07-19 Nk cells activating receptors and their therapeutic and diagnostic uses
DE60115452T DE60115452D1 (de) 2000-07-20 2001-07-19 Nk zellen-aktivierende rezeptoren und deren therapeutische und diagnostische verwendungen
CA002416733A CA2416733A1 (fr) 2000-07-20 2001-07-19 Recepteurs activant les cellules nk et leurs emplois therapeutiques et diagnostiques
EP01956747A EP1301605B1 (fr) 2000-07-20 2001-07-19 Recepteurs activant les cellules nk et leurs emplois therapeutiques et diagnostiques
PCT/IL2001/000664 WO2002008287A2 (fr) 2000-07-20 2001-07-19 Recepteurs activant les cellules nk et leurs emplois therapeutiques et diagnostiques
AU2001278662A AU2001278662B2 (en) 2000-07-20 2001-07-19 NK cells activating receptors and their therapeutic and diagnostic uses
JP2002514191A JP2004504065A (ja) 2000-07-20 2001-07-19 Ｎｋ細胞活性化受容体並びにその治療上および診断上の使用
US10/333,481 US20040072256A1 (en) 2000-07-20 2001-07-19 Nk cells activiating receptors and their therapeutic and diagnostic uses
AU7866201A AU7866201A (en) 2000-07-20 2001-07-19 NK cells activating receptors and their therapeutic and diagnostic uses
AT01956747T ATE311464T1 (de) 2000-07-20 2001-07-19 Nk zellen-aktivierende rezeptoren und deren therapeutische und diagnostische verwendungen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13741900A IL137419A0 (en) 2000-07-20 2000-07-20 Nk cells activating receptors and their therapeutic and diagnostic uses

Publications (1)

Publication Number Publication Date
IL137419A0 true IL137419A0 (en) 2001-07-24

Family

ID=11074420

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13741900A IL137419A0 (en) 2000-07-20 2000-07-20 Nk cells activating receptors and their therapeutic and diagnostic uses

Country Status (9)

Country Link
US (1) US20040072256A1 (fr)
EP (1) EP1301605B1 (fr)
JP (1) JP2004504065A (fr)
AT (1) ATE311464T1 (fr)
AU (2) AU7866201A (fr)
CA (1) CA2416733A1 (fr)
DE (1) DE60115452D1 (fr)
IL (1) IL137419A0 (fr)
WO (1) WO2002008287A2 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003051834A2 (fr) * 2001-12-14 2003-06-26 President And Fellows Of Harvard College Recepteurs immunocellulaires lies aux troubles neurologiques
EP1581169A4 (fr) * 2002-11-08 2008-09-17 Genentech Inc Compositions et procedes de traitement des maladies liees aux cellules k naturelles
AU2003286401A1 (en) * 2002-12-09 2004-06-30 Natspears Ltd. Nk cell receptor conjugates for treating malignancies
EP1445614A1 (fr) * 2003-02-06 2004-08-11 Institut National De La Sante Et De La Recherche Medicale (Inserm) Méthodes d'évaluation in vitro de l'état de progression d'un virus HIV chez un individu
GB0305478D0 (en) 2003-03-10 2003-04-16 Bioxell Spa Diagnostic and prognostic compounds and method
US7825085B2 (en) 2003-06-30 2010-11-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Fragments of NKp44 and NKp46 for targeting viral-infected and tumor cells
WO2005051973A2 (fr) * 2003-11-25 2005-06-09 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Peptides derives de recepteurs de la cytotoxicite naturelle et procedes d'utilisation de ces peptides
CN1954217B (zh) * 2004-02-06 2013-05-08 国立健康与医学研究所 衍生自gp41的多肽、含有所述多肽的疫苗组合物以及用于治疗个体HIV病毒感染的用途
US20080196111A1 (en) * 2005-03-18 2008-08-14 Innate Pharma S.A. Expression Vectors and Methods for Obtaining Nk Cell Specific Expression
WO2007147898A1 (fr) 2006-06-22 2007-12-27 Novo Nordisk A/S Récepteurs hétérodimères solubles et leurs utilisations
JP2009541275A (ja) * 2006-06-22 2009-11-26 ノボ・ノルデイスク・エー／エス 二重特異性抗体の生産
DK2285980T3 (en) 2008-06-02 2017-08-28 Roussy Inst Gustave NATURAL KILLER p30 (NKp30) DYSFUNCTION AND THE BIOLOGICAL APPLICATIONS THEREOF
ES2486673T3 (es) * 2009-03-19 2014-08-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Uso de NKp46 para prevenir la diabetes tipo I
US20140234342A1 (en) 2011-06-21 2014-08-21 Innate Pharma Nkp46-mediated nk cell tuning
EP2828291A1 (fr) 2012-03-21 2015-01-28 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Peptides dérivés du domaine d1 de nkp46
CA2937840C (fr) 2014-01-24 2022-02-15 Garry Taylor Composes immunomodulateurs
AU2017238172B2 (en) * 2016-03-21 2024-06-27 Marengo Therapeutics, Inc. Multispecific and multifunctional molecules and uses thereof
AU2017296354A1 (en) 2016-07-11 2019-01-24 B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University Fusion proteins with extended serum half life
GB201616009D0 (en) 2016-09-20 2016-11-02 Univ Court Of The Univ Of St Andrews The Treatment and/or prevention of sepsis
GB201616006D0 (en) 2016-09-20 2016-11-02 Univ Court Of The Univ Of St Andrews The Cell modulation
GB201616007D0 (en) 2016-09-20 2016-11-02 Univ Court Of The Univ Of St Andrews The Novel Adjuvants
AU2022230011A1 (en) * 2021-03-05 2023-10-19 Shanghai Qilu Pharmaceutical Research And Development Centre Ltd. Antibody against nkp46 and application of antibody

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5912170A (en) * 1991-03-07 1999-06-15 The General Hospital Corporation Redirection of cellular immunity by protein-tyrosine kinase chimeras
US5641863A (en) * 1993-09-30 1997-06-24 University Of Pennsylvania Chimeric IgG Fc receptors
CZ295428B6 (cs) * 1995-02-24 2005-08-17 The General Hospital Corporation Terapeutická buňka pro přesměrování buněčné imunity receptorovými chimérami
EP0828843A1 (fr) * 1995-05-16 1998-03-18 Bristol-Myers Squibb Company Heregulines de recombinaison et leurs fonctions biologiques lors de l'activation d'un recepteur
EP1029049A2 (fr) * 1997-11-07 2000-08-23 Biogen, Inc. Bmog, nouvelle proteine de la famille des glycoproteines de myeline-oligodendrocyte, et son utilisation a des fins immunomodulatrices

Also Published As

Publication number Publication date
EP1301605B1 (fr) 2005-11-30
AU2001278662B2 (en) 2006-09-28
EP1301605A2 (fr) 2003-04-16
US20040072256A1 (en) 2004-04-15
WO2002008287A2 (fr) 2002-01-31
JP2004504065A (ja) 2004-02-12
DE60115452D1 (de) 2006-01-05
AU7866201A (en) 2002-02-05
ATE311464T1 (de) 2005-12-15
CA2416733A1 (fr) 2002-01-31
WO2002008287A3 (fr) 2002-12-19

Similar Documents

Publication Publication Date Title
IL137419A0 (en) Nk cells activating receptors and their therapeutic and diagnostic uses
EP1732602A4 (fr) Mediation cytotoxique de cellules presentant une expression superficielle de mcsp
GB2453677A (en) Lumen-traveling biological interface device
AR055223A1 (es) Caracterizacion y compensacion de electrodos del ecg
IL145535A0 (en) Monoclonal antibodies, antigens and diagnosis and therapy of malignant diseases
DK1449850T3 (da) Humane CDR-graftede antistoffer eller antistoffragmenter deraf
AU2001295531A1 (en) Antisense oligonucleotides against vanilloid receptor 1
MXPA02011142A (es) Plataforma de nanodispositivo multifuncional.
MX2007013626A (es) Anticuerpos dirigidos contra el peptido beta amiloide y procedimientos que usan los mismos.
TW200731987A (en) Cytotoxicity mediation of cells evidencing surface expression of CD44
ITRM20010408A0 (it) Mini-anticorpo umano citotossico per cellule tumorali che esprimono il recettore erbb2.
ATE411833T1 (de) Vorrichtung zum abliefern von pharmazeutika an das innenohr
EP1778351A4 (fr) Verification des caracteristiques d'une lesion au moyen de formes de faisceaux
IL189452A0 (en) Therapy with cd4 binding peptides and radiation
WO2005030797A3 (fr) Nouveaux agonistes du recepteur de la melanocortine
EP1708751A4 (fr) Procedes d'elimination de cellules tumorales par ciblage d'antigene interne expose sur des cellules tumorales apoptotiques
ATE497976T1 (de) Spezifisch an vygfvracl-hla-a24 bindende t-zellen-rezeptoren
EP1667716B8 (fr) Mise en evidence d'une expression surfacielle du cd44 par la cytotoxicite de cellules
IL155611A0 (en) Monoclonal antibodies and cell surface antigens for the detection and treatment of small cell lung cancer (sclc)
MX2009010269A (es) Metodos de tratamiento del cancer mediante administracion de combinaciones de interleucina-18 humana.
HUP0301812A2 (hu) Átvizsgálási (screening) eljárás
BRPI0413428A (pt) xarope seco contendo laratadina
RS20100249A (en) CONJUGATES AND PROCEDURES FOR THEIR PRODUCTION, AND THEIR USE FOR THE TRANSPORT OF MOLECULES THROUGH BIOLOGICAL MEMBRANE
NO20032762L (no) Aktivitetsstyringsanordning
WO2003106681A3 (fr) Oligonucleotides antisens contre pim1