IL136895A0 - Novel pharmaceutical compositions of uridine triphosphate - Google Patents
Novel pharmaceutical compositions of uridine triphosphateInfo
- Publication number
- IL136895A0 IL136895A0 IL13689598A IL13689598A IL136895A0 IL 136895 A0 IL136895 A0 IL 136895A0 IL 13689598 A IL13689598 A IL 13689598A IL 13689598 A IL13689598 A IL 13689598A IL 136895 A0 IL136895 A0 IL 136895A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical compositions
- novel pharmaceutical
- uridine triphosphate
- uridine
- triphosphate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/996,740 US5968913A (en) | 1996-07-03 | 1997-12-23 | Pharmaceutical compositions of uridine triphosphate |
| PCT/US1998/027409 WO1999032085A2 (en) | 1997-12-23 | 1998-12-23 | Novel pharmaceutical compositions of uridine triphosphate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL136895A0 true IL136895A0 (en) | 2001-06-14 |
Family
ID=25543248
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13689598A IL136895A0 (en) | 1997-12-23 | 1998-12-23 | Novel pharmaceutical compositions of uridine triphosphate |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5968913A (xx) |
| EP (1) | EP1041969B1 (xx) |
| JP (1) | JP2001526208A (xx) |
| KR (1) | KR20010033310A (xx) |
| CN (1) | CN1143672C (xx) |
| AR (1) | AR014176A1 (xx) |
| AT (1) | ATE235225T1 (xx) |
| AU (1) | AU747350B2 (xx) |
| BR (1) | BR9814426A (xx) |
| CA (1) | CA2316018A1 (xx) |
| DE (1) | DE69812708T2 (xx) |
| ID (1) | ID26137A (xx) |
| IL (1) | IL136895A0 (xx) |
| NO (1) | NO20003246L (xx) |
| NZ (1) | NZ505821A (xx) |
| WO (1) | WO1999032085A2 (xx) |
| ZA (1) | ZA9811833B (xx) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6319908B1 (en) | 1996-07-03 | 2001-11-20 | Inspire Pharmaceuticals, Inc. | Method for large-scale production of di(uridine 5′-tetraphosphate) and salts thereof |
| US5763447C1 (en) | 1996-07-23 | 2002-05-07 | Inspire Pharmaceuticals | Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds |
| US6872710B2 (en) * | 1997-07-25 | 2005-03-29 | Inspire Pharmaceuticals, Inc. | Di(uridine 5′)-tetraphosphate and salts thereof |
| NZ501696A (en) | 1997-07-25 | 2001-08-31 | Inspire Pharmaceuticals Inc | Method for large-scale production of sodium and ammonium salts of di(uridine 5')-tetraphosphate |
| TW593331B (en) | 1997-07-25 | 2004-06-21 | Inspire Pharmaceuticals Inc | Method for large-scale production of di(uridine 5')-tetraphosphate and salts thereof |
| US7452870B2 (en) | 2000-08-21 | 2008-11-18 | Inspire Pharmaceuticals, Inc. | Drug-eluting stents coated with P2Y12 receptor antagonist compound |
| US7132408B2 (en) | 2000-08-21 | 2006-11-07 | Inspire Pharmaceuticals, Inc. | Composition and method for inhibiting platelet aggregation |
| US7018985B1 (en) | 2000-08-21 | 2006-03-28 | Inspire Pharmaceuticals, Inc. | Composition and method for inhibiting platelet aggregation |
| US6327215B1 (en) * | 2000-09-28 | 2001-12-04 | Vanguard International Semiconductor Corporation | Local bit switch decode circuit and method |
| AR034635A1 (es) | 2001-06-25 | 2004-03-03 | Inspire Pharmaceuticals Inc | Lubricacion de las articulaciones con agonistas del receptor purinergico p2y |
| BR0213897A (pt) * | 2001-11-06 | 2006-05-23 | Inspire Pharmaceuticals Inc | uso de uma formulação farmacêutica que compreende um receptor de nucleotìdeo na preparação de medicamento |
| CN1700894A (zh) * | 2002-10-18 | 2005-11-23 | 莫利化学医药公司 | 使用羊毛硫抗生素治疗干眼病的方法 |
| EP1753445A4 (en) * | 2004-05-06 | 2009-05-20 | Molichem Medicines Inc | TREATMENT OF EYE DISEASES AND EYE TREATMENTS WITH LANTIBIOTIC COMPOSITIONS |
| EP1750740A4 (en) * | 2004-05-06 | 2009-06-10 | Molichem Medicines Inc | TREATMENT OF MEMBRANE-ASSOCIATED DISEASES AND DISORDERS USING COMPOSITIONS CONTAINING LANTIBIOTICS |
| US7368439B2 (en) * | 2005-06-15 | 2008-05-06 | Bar - Ilan University | Dinucleoside poly(borano)phosphate derivatives and uses thereof |
| US20120077778A1 (en) * | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| ES2640485T3 (es) | 2011-08-12 | 2017-11-03 | Universitätsklinikum Freiburg | Uridina y análogos de uridina para el uso en el tratamiento de la enfermedad pulmonar obstructiva crónica |
| US9034442B2 (en) * | 2012-11-30 | 2015-05-19 | Corning Incorporated | Strengthened borosilicate glass containers with improved damage tolerance |
| US10117806B2 (en) * | 2012-11-30 | 2018-11-06 | Corning Incorporated | Strengthened glass containers resistant to delamination and damage |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB916309A (en) * | 1959-12-14 | 1963-01-23 | Ile Auguil Soc Civ | Improvements in and relating to new therapeutic preparation for use as a muscular and nervous stimulant |
| JPS60126220A (ja) * | 1983-12-09 | 1985-07-05 | Otsuka Pharmaceut Factory Inc | 核酸成分組成物 |
| GB9027968D0 (en) * | 1990-12-22 | 1991-02-13 | Fisons Plc | Method of treatment |
| US5164740A (en) * | 1991-04-24 | 1992-11-17 | Yehuda Ivri | High frequency printing mechanism |
| EP0517573A1 (fr) * | 1991-06-05 | 1992-12-09 | Synthelabo | Compositions pharmaceutiques pour le traitement des affections des voies respiratoires |
| FR2677250B1 (fr) * | 1991-06-05 | 1995-01-20 | Synthelabo | Compositions pharmaceutiques contenant de l'adenosine-5-triphosphate disodique. |
| US5292498A (en) * | 1991-06-19 | 1994-03-08 | The University Of North Carolina At Chapel Hill | Method of treating lung disease with uridine triphosphates |
| US5518179A (en) * | 1991-12-04 | 1996-05-21 | The Technology Partnership Limited | Fluid droplets production apparatus and method |
| US5547131A (en) * | 1992-12-04 | 1996-08-20 | Bespak Plc | Dispensing device with spray nozzle and driven piston |
| US5497763A (en) * | 1993-05-21 | 1996-03-12 | Aradigm Corporation | Disposable package for intrapulmonary delivery of aerosolized formulations |
| US5593824A (en) * | 1994-09-02 | 1997-01-14 | Pharmacia Biotech, Inc. | Biological reagent spheres |
| US5628984A (en) * | 1995-07-31 | 1997-05-13 | University Of North Carolina At Chapel Hill | Method of detecting lung disease |
| US6423694B1 (en) * | 1996-02-21 | 2002-07-23 | Inspire Pharmaceuticals, Inc. | Method of treating otitis media with uridine triphosphates and related compounds |
| CN1229114C (zh) * | 1996-03-27 | 2005-11-30 | 印斯拜尔药品股份有限公司 | 用三磷酸尿苷和相关化合物治疗纤毛运动障碍的方法 |
| US5962432A (en) * | 1996-07-03 | 1999-10-05 | Inspire Pharmaceuticals, Inc. | Sterilized, isotonic and pH-adjusted pharmaceutical formulation of uridine triphosphate |
| US5789391A (en) * | 1996-07-03 | 1998-08-04 | Inspire Pharmaceuticals, Inc. | Method of treating sinusitis with uridine triphosphates and related compounds |
| US5763447C1 (en) * | 1996-07-23 | 2002-05-07 | Inspire Pharmaceuticals | Method of preventing or treating pneumonia in immobilized patients with uridine triphosphates and related compounds |
| US6159952A (en) * | 1996-11-07 | 2000-12-12 | Inspire Pharmaceuticals, Inc. | Method of treating bronchitis with uridine triphosphate and related compounds |
-
1997
- 1997-12-23 US US08/996,740 patent/US5968913A/en not_active Expired - Lifetime
-
1998
- 1998-12-23 NZ NZ505821A patent/NZ505821A/xx unknown
- 1998-12-23 WO PCT/US1998/027409 patent/WO1999032085A2/en active IP Right Grant
- 1998-12-23 ID IDW20001428A patent/ID26137A/id unknown
- 1998-12-23 AU AU20922/99A patent/AU747350B2/en not_active Ceased
- 1998-12-23 AT AT98965462T patent/ATE235225T1/de not_active IP Right Cessation
- 1998-12-23 IL IL13689598A patent/IL136895A0/xx unknown
- 1998-12-23 CA CA002316018A patent/CA2316018A1/en not_active Abandoned
- 1998-12-23 DE DE69812708T patent/DE69812708T2/de not_active Expired - Fee Related
- 1998-12-23 JP JP2000525079A patent/JP2001526208A/ja active Pending
- 1998-12-23 AR ARP980106670A patent/AR014176A1/es not_active Application Discontinuation
- 1998-12-23 KR KR1020007006756A patent/KR20010033310A/ko active IP Right Grant
- 1998-12-23 CN CNB988136228A patent/CN1143672C/zh not_active Expired - Fee Related
- 1998-12-23 BR BR9814426-0A patent/BR9814426A/pt not_active IP Right Cessation
- 1998-12-23 ZA ZA9811833A patent/ZA9811833B/xx unknown
- 1998-12-23 EP EP98965462A patent/EP1041969B1/en not_active Expired - Lifetime
-
2000
- 2000-06-21 NO NO20003246A patent/NO20003246L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69812708T2 (de) | 2004-01-29 |
| EP1041969B1 (en) | 2003-03-26 |
| WO1999032085A3 (en) | 1999-09-02 |
| ID26137A (id) | 2000-11-23 |
| AR014176A1 (es) | 2001-02-07 |
| JP2001526208A (ja) | 2001-12-18 |
| ATE235225T1 (de) | 2003-04-15 |
| AU747350B2 (en) | 2002-05-16 |
| NZ505821A (en) | 2002-09-27 |
| DE69812708D1 (de) | 2003-04-30 |
| BR9814426A (pt) | 2001-10-23 |
| CN1143672C (zh) | 2004-03-31 |
| US5968913A (en) | 1999-10-19 |
| WO1999032085A2 (en) | 1999-07-01 |
| CA2316018A1 (en) | 1999-07-01 |
| NO20003246L (no) | 2000-08-23 |
| KR20010033310A (ko) | 2001-04-25 |
| ZA9811833B (en) | 1999-07-20 |
| NO20003246D0 (no) | 2000-06-21 |
| CN1284861A (zh) | 2001-02-21 |
| AU2092299A (en) | 1999-07-12 |
| EP1041969A2 (en) | 2000-10-11 |
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