IL136549A - Orally administrable solid ribavirin dosage forms and process for making them - Google Patents

Orally administrable solid ribavirin dosage forms and process for making them

Info

Publication number
IL136549A
IL136549A IL13654998A IL13654998A IL136549A IL 136549 A IL136549 A IL 136549A IL 13654998 A IL13654998 A IL 13654998A IL 13654998 A IL13654998 A IL 13654998A IL 136549 A IL136549 A IL 136549A
Authority
IL
Israel
Prior art keywords
making
dosage forms
orally administrable
administrable solid
ribavirin dosage
Prior art date
Application number
IL13654998A
Other languages
English (en)
Other versions
IL136549A0 (en
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27130673&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL136549(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/997,172 external-priority patent/US5914128A/en
Priority claimed from US08/997,169 external-priority patent/US5916594A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL136549A0 publication Critical patent/IL136549A0/xx
Publication of IL136549A publication Critical patent/IL136549A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13654998A 1997-12-22 1998-12-21 Orally administrable solid ribavirin dosage forms and process for making them IL136549A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/997,172 US5914128A (en) 1997-12-22 1997-12-22 Orally administrable solid dosage form
US08/997,169 US5916594A (en) 1997-12-22 1997-12-22 Process of making solid ribavirin dosage forms
PCT/US1998/026222 WO1999032128A1 (en) 1997-12-22 1998-12-21 Orally administrable solid ribavirin dosage forms and process for making them

Publications (2)

Publication Number Publication Date
IL136549A0 IL136549A0 (en) 2001-06-14
IL136549A true IL136549A (en) 2005-05-17

Family

ID=27130673

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13654998A IL136549A (en) 1997-12-22 1998-12-21 Orally administrable solid ribavirin dosage forms and process for making them

Country Status (27)

Country Link
US (3) US6337090B1 (hu)
EP (2) EP0991415B1 (hu)
JP (2) JP2001526234A (hu)
KR (1) KR100575389B1 (hu)
CN (1) CN1155388C (hu)
AR (1) AR008977A1 (hu)
AT (1) ATE234103T1 (hu)
AU (1) AU762826B2 (hu)
BR (1) BR9814367A (hu)
CA (4) CA2323849C (hu)
CO (1) CO4970774A1 (hu)
DE (1) DE69812094T2 (hu)
DK (1) DK0991415T3 (hu)
ES (1) ES2191987T3 (hu)
HK (1) HK1034674A1 (hu)
HU (1) HUP0100433A3 (hu)
IL (1) IL136549A (hu)
MY (1) MY119656A (hu)
NO (1) NO20003234L (hu)
NZ (1) NZ504994A (hu)
PE (1) PE20000066A1 (hu)
PL (1) PL190267B1 (hu)
PT (1) PT991415E (hu)
SK (1) SK284520B6 (hu)
TW (1) TW575436B (hu)
WO (1) WO1999032128A1 (hu)
ZA (1) ZA9811726B (hu)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0991415B1 (en) * 1997-12-22 2003-03-12 Schering Corporation Orally administrable solid ribavirin dosage forms and process for making them
US6793934B1 (en) * 1999-12-08 2004-09-21 Shire Laboratories, Inc. Solid oral dosage form
WO2001066026A2 (en) * 2000-03-06 2001-09-13 Tissuelink Medical, Inc. Fluid delivery system and controller for electrosurgical devices
US6720000B2 (en) * 2001-03-19 2004-04-13 Three Rivers Pharmaceutical, Llc Process for producing wet ribavirin pellets
KR20030020137A (ko) * 2001-09-03 2003-03-08 진양제약주식회사 리바비린 건조시럽제
PL368550A1 (en) * 2001-11-02 2005-04-04 Sandoz Ag Process for preparing quick dissolving, high loading ribavirin compositions
DE10227148A1 (de) * 2002-06-18 2004-01-08 Biopartners Gmbh Verwendung von Ribavirin zur Herstellung einer pharmazeutischen Zusammensetzung gegen Bunyaviridae
US7538094B2 (en) * 2002-09-19 2009-05-26 Three Rivers Pharmacueticals, Llc Composition containing ribavirin and use thereof
US20040142903A1 (en) * 2003-01-16 2004-07-22 Par Pharmaceutical Inc. Bioavailable fenofibrate compositions, methods for treating hyperlipidemia and hypercholesterolemia and processes for the preparation of such compositions
BRPI0408846A (pt) * 2003-03-28 2006-07-04 Pharmasset Inc compostos para o tratamento de infecções por flaviviridae
MX2007002784A (es) * 2004-09-09 2009-02-12 Bayer Animal Health Gmbh Composición farmacéutica en forma de dosificación sólida soluble en agua.
US7723310B2 (en) * 2004-10-18 2010-05-25 Three Rivers Pharmaceuticals, Llc Large dose ribavirin formulations
US8062670B2 (en) * 2005-08-05 2011-11-22 3M Innovative Properties Company Compositions exhibiting improved flowability
CA2666814A1 (en) * 2006-08-21 2008-05-29 United Therapeutics Corporation Combination therapy for treatment of viral infections
WO2009142852A2 (en) * 2008-05-22 2009-11-26 3M Innovative Properties Company Process for manufacturing flowable powder drug compositions
EP2309978B1 (en) * 2008-06-26 2018-12-26 3M Innovative Properties Company Dry powder pharmaceutical compositions for pulmonary administration, and methods of manufacturing thereof
WO2010002613A2 (en) * 2008-07-02 2010-01-07 3M Innovative Properties Company Method of making a dry powder pharmaceutical composition
EP2295037A1 (en) 2009-09-11 2011-03-16 Ratiopharm GmbH Pharmaceutical formulation containing Ribavirin
US10363453B2 (en) 2011-02-07 2019-07-30 New Balance Athletics, Inc. Systems and methods for monitoring athletic and physiological performance
CA2752008A1 (en) 2011-09-13 2013-03-13 Universite De Montreal Combination therapy using ribavirin as elf4e inhibitor
CN106389363A (zh) * 2016-10-18 2017-02-15 广东肇庆星湖生物科技股份有限公司 一种利巴韦林口服固体制剂及其制备方法

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US3490742A (en) * 1966-01-14 1970-01-20 Staley Mfg Co A E Compressed tablets
US3622677A (en) * 1969-07-07 1971-11-23 Staley Mfg Co A E Compressed tablets containing compacted starch as binder-disintegrant ingredient
US4211771A (en) * 1971-06-01 1980-07-08 Robins Ronald K Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
DE2735600A1 (de) * 1977-08-06 1979-02-15 Dynamit Nobel Ag Verfahren zur herstellung von phthalid
JPS57146593A (en) * 1981-03-09 1982-09-10 Ajinomoto Co Inc Preparation of ribofuranosyltriazole derivative
US4609675A (en) * 1984-08-17 1986-09-02 The Upjohn Company Stable, high dose, high bulk density ibuprofen granulations for tablet and capsule manufacturing
US4681765A (en) * 1984-09-13 1987-07-21 American Home Products Corporation Rapid releasing triamterene containing gelatin capsule dosage forms for once daily antihypertensive use
US5084445A (en) * 1986-05-01 1992-01-28 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine
US5077279A (en) * 1986-05-01 1991-12-31 University Of Georgia Research Foundation, Inc. 3'-azido-2',3'-dideoxy-5-methylcytidine anti-viral composition
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
JPS63216820A (ja) * 1987-03-05 1988-09-09 Chugai Pharmaceut Co Ltd 抗ウイルス剤
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US5192788A (en) * 1988-05-23 1993-03-09 Georgia State University Foundation, Inc. Porphyrin antiviral compositions
US5109016A (en) * 1988-05-23 1992-04-28 Georgia State University Foundation, Inc. Method for inhibiting infection or replication of human immunodeficiency virus with porphyrin and phthalocyanine antiviral compositions
US5122517A (en) * 1988-06-10 1992-06-16 Regents Of The University Of Minnesota Antiviral combination comprising nucleoside analogs
NZ229453A (en) * 1988-06-10 1991-08-27 Univ Minnesota & Southern Rese A pharmaceutical composition containing purine derivatives with nucleosides such as azt, as antiviral agents
JP2908844B2 (ja) * 1990-06-29 1999-06-21 ヤマサ醤油株式会社 抗ウイルス剤
US5663154A (en) * 1992-01-06 1997-09-02 Glaxo Wellcome Inc. 2',3'-dideoxy-3'-fluoro-purine ribonucleosides
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US5492692A (en) * 1993-08-17 1996-02-20 University Of Kentucky Research Foundation Coated products with potent anti-HIV and antimicrobial properties
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CA2135669A1 (en) 1994-11-10 1996-05-11 Nils O. Johannesson Ribavirin as hepato (liver) protecting agent
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US6106865A (en) * 1995-01-09 2000-08-22 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
NZ302926A (en) * 1995-02-28 1998-10-28 Hoechst Marion Roussel Inc Composition for use as antihistamines comprising piperidinoalkanol derivatives and inert ingredients
US6387365B1 (en) * 1995-05-19 2002-05-14 Schering Corporation Combination therapy for chronic hepatitis C infection
US5733578A (en) * 1995-11-15 1998-03-31 Edward Mendell Co., Inc. Directly compressible high load acetaminophen formulations
US5723589A (en) * 1995-12-21 1998-03-03 Icn Pharmaceuticals Carbohydrate conjugated bio-active compounds
IT1282650B1 (it) * 1996-02-19 1998-03-31 Jagotec Ag Compressa farmaceutica,caratterizzata da elevato aumento di volume a contatto con liquidi biologici
US6172046B1 (en) * 1997-09-21 2001-01-09 Schering Corporation Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection
US5914128A (en) * 1997-12-22 1999-06-22 Schering Corporation Orally administrable solid dosage form
EP0991415B1 (en) * 1997-12-22 2003-03-12 Schering Corporation Orally administrable solid ribavirin dosage forms and process for making them
US5916594A (en) * 1997-12-22 1999-06-29 Schering Corporation Process of making solid ribavirin dosage forms

Also Published As

Publication number Publication date
HUP0100433A3 (en) 2003-01-28
US6051252A (en) 2000-04-18
MY119656A (en) 2005-06-30
PL341230A1 (en) 2001-03-26
IL136549A0 (en) 2001-06-14
ATE234103T1 (de) 2003-03-15
JP2001526234A (ja) 2001-12-18
ES2191987T3 (es) 2003-09-16
DE69812094D1 (de) 2003-04-17
AU762826B2 (en) 2003-07-03
CA2323849A1 (en) 1999-07-01
AR008977A1 (es) 2000-03-08
CA2300452A1 (en) 1999-07-01
KR100575389B1 (ko) 2006-05-03
BR9814367A (pt) 2000-10-17
US6335032B1 (en) 2002-01-01
CA2300452C (en) 2000-11-28
WO1999032128A1 (en) 1999-07-01
KR20010033441A (ko) 2001-04-25
CN1155388C (zh) 2004-06-30
PT991415E (pt) 2003-06-30
JP2006083189A (ja) 2006-03-30
HUP0100433A2 (hu) 2001-12-28
EP0991415A1 (en) 2000-04-12
TW575436B (en) 2004-02-11
EP1321147A1 (en) 2003-06-25
CA2323849C (en) 2002-06-11
NO20003234L (no) 2000-08-21
DK0991415T3 (da) 2003-06-16
HK1034674A1 (en) 2001-11-02
CO4970774A1 (es) 2000-11-07
CA2365412C (en) 2002-09-17
CA2287056C (en) 2000-08-15
SK284520B6 (sk) 2005-05-05
AU2199199A (en) 1999-07-12
CA2287056A1 (en) 1999-07-01
PL190267B1 (pl) 2005-11-30
US6337090B1 (en) 2002-01-08
PE20000066A1 (es) 2000-02-09
EP0991415B1 (en) 2003-03-12
NO20003234D0 (no) 2000-06-21
NZ504994A (en) 2002-10-25
SK8942000A3 (en) 2001-04-09
ZA9811726B (en) 1999-06-21
CA2365412A1 (en) 1999-07-01
DE69812094T2 (de) 2003-12-24
CN1283117A (zh) 2001-02-07

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Legal Events

Date Code Title Description
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees