IL136392A0 - Improved method for the identification and characterization of interacting molecules using automation - Google Patents

Improved method for the identification and characterization of interacting molecules using automation

Info

Publication number
IL136392A0
IL136392A0 IL13639298A IL13639298A IL136392A0 IL 136392 A0 IL136392 A0 IL 136392A0 IL 13639298 A IL13639298 A IL 13639298A IL 13639298 A IL13639298 A IL 13639298A IL 136392 A0 IL136392 A0 IL 136392A0
Authority
IL
Israel
Prior art keywords
interacting molecules
identification
characterization
improved method
present
Prior art date
Application number
IL13639298A
Other languages
English (en)
Original Assignee
Max Planck Gesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft filed Critical Max Planck Gesellschaft
Publication of IL136392A0 publication Critical patent/IL136392A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Vending Machines For Individual Products (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL13639298A 1997-11-27 1998-11-27 Improved method for the identification and characterization of interacting molecules using automation IL136392A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP97120867 1997-11-27
EP97120879 1997-11-27
EP97120880 1997-11-27
PCT/EP1998/007655 WO1999031509A1 (en) 1997-11-27 1998-11-27 Improved method for the identification and characterization of interacting molecules using automation

Publications (1)

Publication Number Publication Date
IL136392A0 true IL136392A0 (en) 2001-06-14

Family

ID=27238345

Family Applications (3)

Application Number Title Priority Date Filing Date
IL13639298A IL136392A0 (en) 1997-11-27 1998-11-27 Improved method for the identification and characterization of interacting molecules using automation
IL13639398A IL136393A0 (en) 1997-11-27 1998-11-27 Identification and characterization of interacting molecules
IL13639498A IL136394A0 (en) 1997-11-27 1998-11-27 Identification and characterization of interacting molecules by automated interaction mating

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL13639398A IL136393A0 (en) 1997-11-27 1998-11-27 Identification and characterization of interacting molecules
IL13639498A IL136394A0 (en) 1997-11-27 1998-11-27 Identification and characterization of interacting molecules by automated interaction mating

Country Status (10)

Country Link
US (1) US6664048B1 (de)
EP (3) EP1042670B1 (de)
JP (3) JP2002507386A (de)
AT (2) ATE269974T1 (de)
AU (3) AU1757599A (de)
CA (3) CA2311705A1 (de)
DE (2) DE69822510T2 (de)
GB (1) GB2338711B (de)
IL (3) IL136392A0 (de)
WO (3) WO1999028745A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7029847B2 (en) 2000-05-16 2006-04-18 Massachusetts Institute Of Technology Methods and compositions for interaction trap assays
AU2001263155A1 (en) 2000-05-16 2001-11-26 Massachusetts Institute Of Technology Methods and compositions for interaction trap assays
WO2001096597A2 (en) * 2000-06-13 2001-12-20 Glaxo Group Limited High throughput screening of compounds for biological activity
DE60130211T2 (de) * 2000-06-23 2008-05-29 Domantis Ltd., Brentford Matrix-screening-verfahren
JP4024994B2 (ja) 2000-06-30 2007-12-19 株式会社東芝 半導体発光素子
WO2002004628A2 (en) * 2000-07-06 2002-01-17 Genvec, Inc. Method of identifying a binding partner of a gene product
DE50015173D1 (de) 2000-07-13 2008-07-03 Ct Concept Technologie Ag Verfahren und vorrichtung zur zustandsabhängigen regelung des transienten verhaltens von leistungshalbleiterschaltern
US7390458B2 (en) * 2000-10-13 2008-06-24 Irm Llc High throughput processing system and method of using
EP1975620A3 (de) 2001-03-02 2008-12-24 GPC Biotech AG Dreihybrid-Testsystem
EP1243327A1 (de) * 2001-03-19 2002-09-25 BioChip Technologies GmbH Oberfläche mit einem Muster aus Zellen und Verfahren zu deren Herstellung
US7219016B2 (en) * 2001-04-20 2007-05-15 Yale University Systems and methods for automated analysis of cells and tissues
WO2002103608A2 (en) * 2001-06-14 2002-12-27 Ramot University Authority For Applied Research & Industrial Development Ltd. Method of expanding a biological network
DE10141522C1 (de) * 2001-08-24 2003-03-06 Siemens Ag Verfahren zur Herstellung einer Leuchtstoffschicht
US20020094519A1 (en) * 2002-03-07 2002-07-18 Agencourt Bioscience Corporation Detection of protein interactions
US20040067532A1 (en) 2002-08-12 2004-04-08 Genetastix Corporation High throughput generation and affinity maturation of humanized antibody
US20050074780A1 (en) * 2003-10-01 2005-04-07 Bryhan Marie D. Device for analyzing slides
WO2006040154A2 (en) * 2004-10-14 2006-04-20 Dublin City University Prokaryotic two hybrid system
US8034180B2 (en) 2005-10-11 2011-10-11 Applied Materials, Inc. Method of cooling a wafer support at a uniform temperature in a capacitively coupled plasma reactor
US7988872B2 (en) 2005-10-11 2011-08-02 Applied Materials, Inc. Method of operating a capacitively coupled plasma reactor with dual temperature control loops
US8157951B2 (en) 2005-10-11 2012-04-17 Applied Materials, Inc. Capacitively coupled plasma reactor having very agile wafer temperature control
US8092638B2 (en) 2005-10-11 2012-01-10 Applied Materials Inc. Capacitively coupled plasma reactor having a cooled/heated wafer support with uniform temperature distribution
US20070091540A1 (en) * 2005-10-20 2007-04-26 Applied Materials, Inc. Method of processing a workpiece in a plasma reactor using multiple zone feed forward thermal control
US7932030B2 (en) * 2007-04-05 2011-04-26 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College System for pulling out regulatory elements using yeast
CA2697193C (en) 2007-09-14 2017-06-06 Adimab, Inc. Rationally designed, synthetic antibody libraries and uses therefor
US8877688B2 (en) 2007-09-14 2014-11-04 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
AU2011279073B2 (en) 2010-07-16 2016-06-09 Adimab, Llc Antibody libraries
WO2018011422A1 (en) * 2016-07-15 2018-01-18 Danmarks Tekniske Universitet Plating cells and corresponding picking colonies
US20210285062A1 (en) * 2017-05-16 2021-09-16 The Regents Of The University Of California Fluorescence detection in yeast colonies
US20210147790A1 (en) * 2019-11-06 2021-05-20 General Automation Lab Technologies Inc. Method for picking biological sample

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283173A (en) * 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
US5789184A (en) 1993-03-31 1998-08-04 Cadus Pharmaceutical Corporation Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor
US5503977A (en) 1994-04-22 1996-04-02 California Institute Of Technology Split ubiquitin protein sensor
EP0830459B1 (de) * 1995-04-11 2007-01-24 The General Hospital Corporation Reverse "two-hybrid"-systeme
US5569588A (en) * 1995-08-09 1996-10-29 The Regents Of The University Of California Methods for drug screening
EP0790304A1 (de) * 1995-12-21 1997-08-20 AMERSHAM INTERNATIONAL plc Auf Nachweismethoden bezogene Verbesserungen
US6083693A (en) * 1996-06-14 2000-07-04 Curagen Corporation Identification and comparison of protein-protein interactions that occur in populations
WO1998007845A1 (en) * 1996-08-23 1998-02-26 President And Fellows Of Harvard College Interaction trap assay, reagents and uses thereof

Also Published As

Publication number Publication date
EP1036329A1 (de) 2000-09-20
WO1999028745A1 (en) 1999-06-10
AU762954B2 (en) 2003-07-10
CA2311927A1 (en) 1999-06-10
ATE269974T1 (de) 2004-07-15
AU2050499A (en) 1999-06-16
GB2338711A (en) 1999-12-29
AU2050599A (en) 1999-06-16
CA2311896A1 (en) 1999-06-24
WO1999031509A1 (en) 1999-06-24
AU760908B2 (en) 2003-05-22
DE69824757T2 (de) 2005-10-20
DE69824757D1 (de) 2004-07-29
JP2002507386A (ja) 2002-03-12
ATE262178T1 (de) 2004-04-15
EP1042670B1 (de) 2004-03-17
EP1036324A1 (de) 2000-09-20
DE69822510D1 (de) 2004-04-22
WO1999028744A1 (en) 1999-06-10
IL136393A0 (en) 2001-06-14
GB2338711A8 (en) 2000-01-26
JP2002508517A (ja) 2002-03-19
GB2338711B (en) 2000-11-15
GB9923293D0 (en) 1999-12-08
EP1036324B1 (de) 2004-06-23
EP1042670A1 (de) 2000-10-11
IL136394A0 (en) 2001-06-14
CA2311705A1 (en) 1999-06-10
AU1757599A (en) 1999-07-05
US6664048B1 (en) 2003-12-16
JP2001525186A (ja) 2001-12-11
DE69822510T2 (de) 2005-03-24

Similar Documents

Publication Publication Date Title
IL136392A0 (en) Improved method for the identification and characterization of interacting molecules using automation
DK1095277T3 (da) System til cellebaseret screening
CA2187783A1 (en) Assays and devices for the detection of extrahepatic biliary atresia
DE69719057D1 (de) Verfahren zur signalverstärkung
DE59814441D1 (de) Verwendung von kontrollflächen zur detektion von störproben in einem nachweisverfahren
WO2003036256A3 (en) Method and apparatus for increasing the dynamic range and accuracy of binding assays
DE60030145D1 (de) Nachweisverfahren für kurze sequenzvarianten
MY104991A (en) Method and appratus for collecting and recovering microorganisms.
WO2001038566A3 (en) Screening method for candidate drugs
NO974000D0 (no) Fremgangsmåte og forbindelser for påvisning av analytter, ved hjelp av remanensmålinger, samt anvendelse av slike forbindelser
ES2168310T3 (es) Reactivos y metodos de deteccion y de cuantificacion de la testosterona en muestras de fluido.
AU9497998A (en) Method for detecting antibodies in a sample
WO2002058533A3 (en) Process for determining target function and identifying drug leads
EP1188060A4 (de) Verfahren und apparatur zum präsentieren von daten von thrombose- und haemostaseassays
ATE284955T1 (de) Map-kinase: polypeptide, polynukleotide und ihre verwendung
DE60025380D1 (de) Ein-schritttest zum nachweis von antimikrobiellen rückständen in eiern
EP1268842A4 (de) Verbessertes verfahren für reverses n-hybrid-screening
WO2001040312A3 (en) Naive screening method
WO2002095054A3 (en) Method of determining protein interaction inhibitors
DE69635025D1 (de) Neues verfahren zum nachweis von cryptosporidium
WO1997019178A3 (de) Autoantigene Metallproteasen und Verfahren zur Diagnose von Autoimmunkrankheiten
WO2002042467A8 (en) Aspergillus fumigatus profilin
DK0970249T3 (da) Fremgangsmåde til detektion af muterede alleler
WO2003057832A3 (en) Identification of genes controlling complex traits
AU2001259172A8 (en) Apparatus and methods for assays of one or more analytes