IL134373A0 - Macrolides with antitumor activity - Google Patents

Macrolides with antitumor activity

Info

Publication number
IL134373A0
IL134373A0 IL13437398A IL13437398A IL134373A0 IL 134373 A0 IL134373 A0 IL 134373A0 IL 13437398 A IL13437398 A IL 13437398A IL 13437398 A IL13437398 A IL 13437398A IL 134373 A0 IL134373 A0 IL 134373A0
Authority
IL
Israel
Prior art keywords
macrolides
sugar
antitumor activity
rhodinose
micromonospora
Prior art date
Application number
IL13437398A
Other languages
English (en)
Original Assignee
Ruffles Graham Keith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ruffles Graham Keith filed Critical Ruffles Graham Keith
Publication of IL134373A0 publication Critical patent/IL134373A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/12Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
    • C07D493/20Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/29Micromonospora
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/867Micromonospora

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
IL13437398A 1997-08-04 1998-08-04 Macrolides with antitumor activity IL134373A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9716486.7A GB9716486D0 (en) 1997-08-04 1997-08-04 A new macrolide with antitumor activity
PCT/GB1998/002336 WO1999007710A1 (fr) 1997-08-04 1998-08-04 Macrolides possedant une activite anti-tumorale

Publications (1)

Publication Number Publication Date
IL134373A0 true IL134373A0 (en) 2001-04-30

Family

ID=10816968

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13437398A IL134373A0 (en) 1997-08-04 1998-08-04 Macrolides with antitumor activity

Country Status (20)

Country Link
US (1) US6395711B1 (fr)
EP (1) EP1001957B8 (fr)
JP (1) JP2001512733A (fr)
KR (1) KR20010022705A (fr)
CN (1) CN1109687C (fr)
AT (1) ATE245652T1 (fr)
AU (1) AU752169B2 (fr)
BR (1) BR9812426A (fr)
CA (1) CA2299269A1 (fr)
DE (1) DE69816621T2 (fr)
DK (1) DK1001957T3 (fr)
ES (1) ES2202880T3 (fr)
GB (1) GB9716486D0 (fr)
HU (1) HUP0002712A3 (fr)
IL (1) IL134373A0 (fr)
MX (1) MXPA00001303A (fr)
NO (1) NO20000582L (fr)
PL (1) PL338514A1 (fr)
PT (1) PT1001957E (fr)
WO (1) WO1999007710A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0317128D0 (en) * 2003-07-22 2003-08-27 Inst Biomar Sa Use of antitumoral compounds
CN101983964B (zh) * 2010-04-14 2013-08-14 中国医药集团总公司四川抗菌素工业研究所 一种具有抗菌和抗肿瘤活性的化合物、制备方法与用途
CN107287131B (zh) * 2017-05-27 2020-10-16 福建省微生物研究所 一种小单孢菌、其代谢产物大环内酰胺化合物和在抗肿瘤中的应用
CN109651329B (zh) * 2019-01-15 2022-11-25 浙江海正药业股份有限公司 十四元大环内酯类化合物、其制备方法及其用途
CN115197192B (zh) * 2022-07-26 2023-09-29 郑州轻工业大学 一种大环内酯化合物曲霉内酯a
CN115504990B (zh) * 2022-10-31 2024-01-30 福建省微生物研究所 一种含糖-螺环-大环内酯类化合物fw-5-39及制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4639467A (en) 1984-04-25 1987-01-27 Celino Martin S Antibiotic Crismaicin A and compositions thereof
EP0322748B1 (fr) 1987-12-24 1994-04-20 Nippon Kayaku Kabushiki Kaisha L'antibiotique NK 86-0279, son procédé de production et son utilisation
US5003056A (en) 1987-12-24 1991-03-26 Nippon Kayaku Kabushiki Kaisha Antibiotic NK86-0279, process for production of the same and application of the same

Also Published As

Publication number Publication date
PL338514A1 (en) 2000-11-06
US6395711B1 (en) 2002-05-28
DK1001957T3 (da) 2003-10-06
MXPA00001303A (es) 2002-04-24
GB9716486D0 (en) 1997-10-08
ATE245652T1 (de) 2003-08-15
EP1001957B8 (fr) 2003-10-22
NO20000582L (no) 2000-03-21
CN1276791A (zh) 2000-12-13
AU752169B2 (en) 2002-09-05
BR9812426A (pt) 2000-09-19
CA2299269A1 (fr) 1999-02-18
EP1001957A1 (fr) 2000-05-24
HUP0002712A2 (hu) 2000-12-28
CN1109687C (zh) 2003-05-28
WO1999007710A1 (fr) 1999-02-18
DE69816621D1 (de) 2003-08-28
HUP0002712A3 (en) 2003-03-28
DE69816621T2 (de) 2004-06-09
JP2001512733A (ja) 2001-08-28
PT1001957E (pt) 2003-11-28
EP1001957B1 (fr) 2003-07-23
ES2202880T3 (es) 2004-04-01
AU8637898A (en) 1999-03-01
NO20000582D0 (no) 2000-02-04
KR20010022705A (ko) 2001-03-26

Similar Documents

Publication Publication Date Title
CA2110386A1 (fr) Methode pour la synthezse enzymatique de glycosides oligosaccharidiques alpha-sialyles
SE9301677L (sv) Syntesmetod
CA2054329A1 (fr) Procede de preparation du trehalose et de l'isomaltulose
CA2305619A1 (fr) Nouveau glycosaminoglycan et compositions medicamenteuses le contenant
EP0171964A3 (fr) Sirops de maltose et de maltitol et leur préparation
AU564256B2 (en) Rebeccamycin and 5:n-methyl and 5:,2;,3;,6;-tetraacetate derivatives
IL134373A0 (en) Macrolides with antitumor activity
EP1130101A3 (fr) Transférase et amylase, procédé de production de ces enzymes, utilisation et gènes les codant
AU6364094A (en) Anthracyclines with unusually high activity against cells resistant to doxorubicin and its analogs
NO934293L (no) Fremgangsmåte og streptomycesstamme for fremstilling av antiparastiske forbindelser
Boivin et al. The influence of enzyme systems on MIC
MY104067A (en) Epipodophyllotoxin glucoside 4''-acyl derivatives
EP0179468A3 (en) Production of uridine
WO1994014954A3 (fr) Kdo aldolase et reactions de condensation associees
GR3036186T3 (en) Process for producing disaccharides and novel saccharides
TR200000245T2 (tr) Bir deoksiüridin türevinin hazırlanmasına mahsus yöntem
ES8706816A1 (es) Un procedimiento para la preparacion de un nuevo compuesto denominado sustancia n. 51262 por cultivo de un microorganismo del genero streptomyces
ES2139541A1 (es) Procedimiento de fabricacion de un hidrolizado de almidon con alto contenido en dextrosa.
KR970065726A (ko) 말토올리고실투라노오스와 말토올리고실파라티노오스를 함유한 당 조성물, 그 제조방법 및 용도
JPS5344692A (en) Preparation of 2,3,-cyclic nucleotide by fermentation process
GB1492454A (en) Use of amino-sugar derivatives in animal nutrition
HK1012410A1 (en) Catabolite non-repressed substrate-limited yeast strains.
ES8506043A1 (es) Un procedimiento para la preparacion de una macrolida.
EP0730033A3 (fr) Procédé pour la préparation de glycosphingolipide
JPS5623895A (en) Increase of yield of glucose