IL133659A - Transdermal Therapeutic System (TTS) for the administration of sex steroid hormones - Google Patents
Transdermal Therapeutic System (TTS) for the administration of sex steroid hormonesInfo
- Publication number
- IL133659A IL133659A IL13365998A IL13365998A IL133659A IL 133659 A IL133659 A IL 133659A IL 13365998 A IL13365998 A IL 13365998A IL 13365998 A IL13365998 A IL 13365998A IL 133659 A IL133659 A IL 133659A
- Authority
- IL
- Israel
- Prior art keywords
- tts
- active
- ingredient
- steroid
- fact
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F13/00—Bandages or dressings; Absorbent pads
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19728517A DE19728517C2 (de) | 1997-07-04 | 1997-07-04 | TTS zur Verabreichung von Sexualsteroidhormonen und Verfahren zu seiner Herstellung |
PCT/EP1998/003950 WO1999001116A1 (de) | 1997-07-04 | 1998-06-29 | Transdermales therapeutisches system (tts) zur verabreichung von sexualsteroidhormonen |
Publications (2)
Publication Number | Publication Date |
---|---|
IL133659A0 IL133659A0 (en) | 2001-04-30 |
IL133659A true IL133659A (en) | 2004-07-25 |
Family
ID=7834591
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13365998A IL133659A (en) | 1997-07-04 | 1998-06-29 | Transdermal Therapeutic System (TTS) for the administration of sex steroid hormones |
Country Status (18)
Country | Link |
---|---|
US (1) | US6562367B1 (ko) |
EP (1) | EP1003490B1 (ko) |
JP (1) | JP2002508778A (ko) |
KR (1) | KR100370647B1 (ko) |
CN (1) | CN1195501C (ko) |
AT (1) | ATE223710T1 (ko) |
AU (1) | AU749474B2 (ko) |
BR (1) | BR9815512A (ko) |
CA (1) | CA2295720A1 (ko) |
DE (2) | DE19728517C2 (ko) |
DK (1) | DK1003490T3 (ko) |
ES (1) | ES2181257T3 (ko) |
HK (1) | HK1031693A1 (ko) |
IL (1) | IL133659A (ko) |
NZ (1) | NZ502352A (ko) |
PT (1) | PT1003490E (ko) |
WO (1) | WO1999001116A1 (ko) |
ZA (1) | ZA985864B (ko) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19821788C1 (de) * | 1998-05-15 | 1999-12-02 | Sanol Arznei Schwarz Gmbh | Transdermales Therapeutisches System (TTS) Pergolid enthaltend |
DE19828274C2 (de) * | 1998-06-25 | 2002-11-28 | Rottapharm Bv | Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren |
DE19828273B4 (de) | 1998-06-25 | 2005-02-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren |
AR022471A1 (es) * | 1999-02-02 | 2002-09-04 | Ortho Mcneil Pharm Inc | Metodo para la fabricacion de matrices transdermicas |
DE10012908B4 (de) * | 2000-03-16 | 2005-03-17 | Lts Lohmann Therapie-Systeme Ag | Stabilisierte übersättigte transdermale therapeutische Matrixsysteme und Verfahren zu ihrer Herstellung |
DE10033855A1 (de) * | 2000-07-12 | 2002-01-31 | Hexal Ag | Matrixkontrolliertes transdermales System mit Sulfonsäuresalz eines ACE-Hemmers |
DE10141651B4 (de) * | 2001-08-24 | 2007-02-15 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung |
GB0409498D0 (en) * | 2004-04-28 | 2004-06-02 | Hunter Fleming Ltd | Transdermal steroid formulation |
US20060067995A1 (en) * | 2004-07-02 | 2006-03-30 | Heng Wan Sia P | Topical and/or transdermal bioactive compound delivery system |
HUE055562T2 (hu) | 2011-11-23 | 2021-11-29 | Therapeuticsmd Inc | Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
KR20180126582A (ko) | 2016-04-01 | 2018-11-27 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 스테로이드 호르몬 약제학적 조성물 |
TWI741168B (zh) | 2017-04-28 | 2021-10-01 | 日商日東電工股份有限公司 | 經皮吸收製劑 |
US11633405B2 (en) | 2020-02-07 | 2023-04-25 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical formulations |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6139868A (en) * | 1986-08-28 | 2000-10-31 | Lts Lohmann Therapie-Systeme Gmbh & Co. Kg | Transdermal therapeutic system, its use and production process |
CA2075517C (en) * | 1992-04-01 | 1997-03-11 | John Wick | Transdermal patch incorporating a polymer film incorporated with an active agent |
DE4310012A1 (de) * | 1993-03-27 | 1994-09-29 | Roehm Gmbh | Dermales therapeutisches System aus einer schmelzfähigen Poly(meth)acrylat-Mischung |
DE4332094C2 (de) * | 1993-09-22 | 1995-09-07 | Lohmann Therapie Syst Lts | Lösemittelfrei herstellbares Wirkstoffpflaster und Verfahren zu seiner Herstellung |
WO1997035564A1 (de) * | 1996-03-25 | 1997-10-02 | Lts Lohmann Therapie-Systeme Gmbh | Transdermales therapeutisches system mit geringer applikationsdicke und hoher flexibilität sowie herstellungsverfahren |
DE19653605C2 (de) | 1996-12-20 | 2002-11-28 | Roehm Gmbh | Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems |
-
1997
- 1997-07-04 DE DE19728517A patent/DE19728517C2/de not_active Expired - Fee Related
-
1998
- 1998-06-29 US US09/462,033 patent/US6562367B1/en not_active Expired - Fee Related
- 1998-06-29 DK DK98939550T patent/DK1003490T3/da active
- 1998-06-29 JP JP50630199A patent/JP2002508778A/ja not_active Ceased
- 1998-06-29 IL IL13365998A patent/IL133659A/en not_active IP Right Cessation
- 1998-06-29 EP EP98939550A patent/EP1003490B1/de not_active Expired - Lifetime
- 1998-06-29 DE DE59805536T patent/DE59805536D1/de not_active Expired - Fee Related
- 1998-06-29 AT AT98939550T patent/ATE223710T1/de not_active IP Right Cessation
- 1998-06-29 KR KR10-2000-7000015A patent/KR100370647B1/ko not_active IP Right Cessation
- 1998-06-29 WO PCT/EP1998/003950 patent/WO1999001116A1/de active IP Right Grant
- 1998-06-29 ES ES98939550T patent/ES2181257T3/es not_active Expired - Lifetime
- 1998-06-29 AU AU88021/98A patent/AU749474B2/en not_active Ceased
- 1998-06-29 NZ NZ502352A patent/NZ502352A/en unknown
- 1998-06-29 CN CNB988088606A patent/CN1195501C/zh not_active Expired - Fee Related
- 1998-06-29 PT PT98939550T patent/PT1003490E/pt unknown
- 1998-06-29 BR BR9815512-1A patent/BR9815512A/pt not_active Application Discontinuation
- 1998-06-29 CA CA002295720A patent/CA2295720A1/en not_active Abandoned
- 1998-07-03 ZA ZA985864A patent/ZA985864B/xx unknown
-
2001
- 2001-04-02 HK HK01102358A patent/HK1031693A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU749474B2 (en) | 2002-06-27 |
US6562367B1 (en) | 2003-05-13 |
NZ502352A (en) | 2001-08-31 |
ZA985864B (en) | 1998-10-23 |
HK1031693A1 (en) | 2001-06-22 |
DK1003490T3 (da) | 2002-10-14 |
CN1195501C (zh) | 2005-04-06 |
WO1999001116A1 (de) | 1999-01-14 |
DE59805536D1 (de) | 2002-10-17 |
EP1003490B1 (de) | 2002-09-11 |
CA2295720A1 (en) | 1999-01-14 |
ATE223710T1 (de) | 2002-09-15 |
DE19728517C2 (de) | 1999-11-11 |
KR20010021493A (ko) | 2001-03-15 |
AU8802198A (en) | 1999-01-25 |
CN1269716A (zh) | 2000-10-11 |
EP1003490A1 (de) | 2000-05-31 |
BR9815512A (pt) | 2001-11-27 |
PT1003490E (pt) | 2003-01-31 |
DE19728517A1 (de) | 1999-01-07 |
JP2002508778A (ja) | 2002-03-19 |
IL133659A0 (en) | 2001-04-30 |
KR100370647B1 (ko) | 2003-02-05 |
ES2181257T3 (es) | 2003-02-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |