IL133585A0 - Soluble prodrugs of paclitaxel - Google Patents
Soluble prodrugs of paclitaxelInfo
- Publication number
- IL133585A0 IL133585A0 IL13358597A IL13358597A IL133585A0 IL 133585 A0 IL133585 A0 IL 133585A0 IL 13358597 A IL13358597 A IL 13358597A IL 13358597 A IL13358597 A IL 13358597A IL 133585 A0 IL133585 A0 IL 133585A0
- Authority
- IL
- Israel
- Prior art keywords
- paclitaxel
- onium salts
- methods
- novel
- salts
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1997/010746 WO1998058927A1 (en) | 1997-06-20 | 1997-06-20 | Soluble prodrugs of paclitaxel |
Publications (1)
Publication Number | Publication Date |
---|---|
IL133585A0 true IL133585A0 (en) | 2001-04-30 |
Family
ID=22261122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13358597A IL133585A0 (en) | 1997-06-20 | 1997-06-20 | Soluble prodrugs of paclitaxel |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1001769B1 (de) |
JP (1) | JP2002505682A (de) |
AT (1) | ATE219363T1 (de) |
AU (1) | AU3574097A (de) |
CA (1) | CA2294606A1 (de) |
DE (1) | DE69713526D1 (de) |
HU (1) | HUP0002521A3 (de) |
IL (1) | IL133585A0 (de) |
SK (1) | SK182599A3 (de) |
WO (1) | WO1998058927A1 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU777620B2 (en) * | 1999-04-09 | 2004-10-21 | Jessie L.S. Au | Methods and compositions for enhancing delivery of therapeutic agents to tissues |
US6541508B2 (en) | 1999-09-13 | 2003-04-01 | Nobex Corporation | Taxane prodrugs |
US6380405B1 (en) | 1999-09-13 | 2002-04-30 | Nobex Corporation | Taxane prodrugs |
US6713454B1 (en) | 1999-09-13 | 2004-03-30 | Nobex Corporation | Prodrugs of etoposide and etoposide analogs |
US6638906B1 (en) | 1999-12-13 | 2003-10-28 | Nobex Corporation | Amphiphilic polymers and polypeptide conjugates comprising same |
JP2004520398A (ja) * | 2001-01-18 | 2004-07-08 | ファルマシア・アンド・アップジョン・カンパニー | 経口生物学的利用能が改善されたパクリタキセルの化学療法マイクロエマルジョン組成物 |
US7115565B2 (en) | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
US7351542B2 (en) | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
EP2390262A1 (de) | 2003-05-16 | 2011-11-30 | Intermune, Inc. | Synthetische Chemokinrezeptorliganden und Verwendungsverfahren dafür |
US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
US20060188508A1 (en) | 2005-02-17 | 2006-08-24 | Cohen Stanley N | Methods and compositions for modulating angiogenesis |
WO2009006613A1 (en) | 2007-07-03 | 2009-01-08 | Children's Hospital & Research Center At Oakland | Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting |
EP2859916B1 (de) | 2008-05-22 | 2017-11-29 | Galera Labs, LLC | Antimitotika mit Superoxid Dismutase Mimetika für die Kombinationstherapie gegen Krebs |
EP2310507A4 (de) | 2008-07-08 | 2013-03-20 | David Gladstone Inst | Verfahren und zusammensetzungen zur angiogenesemodulierung |
CN103607888A (zh) * | 2011-04-08 | 2014-02-26 | 斯法尔制药私人有限公司 | 取代的甲基甲酰基试剂以及使用所述试剂改进化合物的物理化学性质和/或药代动力学性质的方法 |
CN104582717B (zh) | 2012-07-19 | 2018-03-13 | 雷德伍德生物科技股份有限公司 | 对cd22有特异性的抗体及其使用方法 |
WO2014074218A1 (en) | 2012-11-12 | 2014-05-15 | Redwood Bioscience, Inc. | Compounds and methods for producing a conjugate |
EP3300745B9 (de) | 2013-02-15 | 2020-04-15 | The Regents of the University of California | Chimärer antigen-rezeptor und verfahren zur verwendung davon |
EP2970124B1 (de) | 2013-03-14 | 2019-05-22 | The Board of Trustees of the Leland Stanford Junior University | Mitochondriale aldehyd-dehydrogenase-2-modulatoren und verfahren zur verwendung davon |
WO2015081282A1 (en) | 2013-11-27 | 2015-06-04 | Redwood Bioscience, Inc. | Hydrazinyl-pyrrolo compounds and methods for producing a conjugate |
HUE051255T2 (hu) | 2014-02-19 | 2021-03-01 | Aviv Therapeutics Inc | Mitokondriális aldehid dehidrogenáz 2 (ALDH2) kötõ policiklusos amidok és alkalmazásuk rák kezelésére |
EP3373977A4 (de) | 2015-11-12 | 2019-07-17 | The Board of Trustees of the Leland Stanford Junior University | Zellenpenetrierende, guanidiniumreiche oligophosphotriester zur wirkstoff- und sondenfreisetzung |
EP3377523A4 (de) | 2015-11-19 | 2019-06-19 | The Regents of The University of California | Konditionell reprimierbare immunzellenrezeptoren und verfahren zur verwendung davon |
EP3231421A1 (de) | 2016-04-11 | 2017-10-18 | Greenaltech, S.L. | Verwendungen eines carotenoids bei der behandlung oder prävention von durch stress verursachten störungen |
WO2017189432A1 (en) | 2016-04-26 | 2017-11-02 | R.P. Scherer Technologies, Llc | Antibody conjugates and methods of making and using the same |
SI3463308T1 (sl) | 2016-06-01 | 2022-04-29 | Servier IP UK Limited | Formulacije polialkilenoksidne asparaginaze in postopki za pripravo in uporabo le-teh |
AU2018211081A1 (en) | 2017-01-18 | 2019-07-18 | Bioatla, Inc. | Chimeric antigen receptors against Axl or Ror2 and methods of use thereof |
EP3388082A1 (de) | 2017-04-13 | 2018-10-17 | Galera Labs, LLC | Kombinationskrebsimmuntherapie mit makrocyclischem pentaaza-ringkomplex |
CN111902147A (zh) | 2018-01-31 | 2020-11-06 | 加莱拉实验室有限责任公司 | 五氮杂大环状环配合物和基于铂的抗癌剂的组合癌症治疗 |
BR112020020930A2 (pt) | 2018-04-11 | 2021-03-02 | Ohio State Innovation Foundation | composição de liberação de fármaco, método para tratar um distúrbio oftalmológico e kit |
MX2021000644A (es) | 2018-07-18 | 2021-08-19 | Manzanita Pharmaceuticals Inc | Conjugados para suministrar un agente contra el cancer a las celulas nerviosas, metodos de uso y metodos para la elaboracion de los mismos. |
WO2020206033A1 (en) | 2019-04-02 | 2020-10-08 | Kenjockety Biotechnology, Inc. | Efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto |
JP2023512196A (ja) | 2020-01-29 | 2023-03-24 | ケンジョッケティ バイオテクノロジー,インク. | 抗mdr1抗体およびその使用 |
CA3182472A1 (en) | 2020-06-04 | 2021-12-09 | Kenjockety Biotechnology, Inc. | Anti-abcg2 antibodies and uses thereof |
JP2023528417A (ja) | 2020-06-04 | 2023-07-04 | ケンジョッケティ バイオテクノロジー,インク. | Abcg2排出ポンプ-がん抗原多重特異性抗体並びにそれらに関連する組成物、試薬、キット、及び方法 |
EP4208483A1 (de) | 2020-09-02 | 2023-07-12 | Kenjockety Biotechnology, Inc. | Anti-abcc1-antikörper und verwendungen davon |
WO2022103603A1 (en) | 2020-11-13 | 2022-05-19 | Kenjockety Biotechnology, Inc. | Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof |
WO2023114658A1 (en) | 2021-12-13 | 2023-06-22 | Kenjockety Biotechnology, Inc. | Anti-abcb1 antibodies |
WO2023159220A1 (en) | 2022-02-18 | 2023-08-24 | Kenjockety Biotechnology, Inc. | Anti-cd47 antibodies |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4013595A (en) * | 1995-10-27 | 1997-05-15 | Scripps Research Institute, The | Method for treating cancer using taxoid onium salt prodrugs |
SK157599A3 (en) * | 1997-05-27 | 2002-10-08 | Baker Norton Pharma | Method and compositions for administering taxanes orally to human patients |
-
1997
- 1997-06-20 JP JP50434699A patent/JP2002505682A/ja not_active Ceased
- 1997-06-20 CA CA002294606A patent/CA2294606A1/en not_active Abandoned
- 1997-06-20 EP EP97932226A patent/EP1001769B1/de not_active Expired - Lifetime
- 1997-06-20 WO PCT/US1997/010746 patent/WO1998058927A1/en not_active Application Discontinuation
- 1997-06-20 IL IL13358597A patent/IL133585A0/xx unknown
- 1997-06-20 DE DE69713526T patent/DE69713526D1/de not_active Expired - Lifetime
- 1997-06-20 HU HU0002521A patent/HUP0002521A3/hu unknown
- 1997-06-20 AU AU35740/97A patent/AU3574097A/en not_active Abandoned
- 1997-06-20 AT AT97932226T patent/ATE219363T1/de not_active IP Right Cessation
- 1997-06-20 SK SK1825-99A patent/SK182599A3/sk unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0002521A2 (hu) | 2001-06-28 |
EP1001769B1 (de) | 2002-06-19 |
SK182599A3 (en) | 2000-07-11 |
EP1001769A1 (de) | 2000-05-24 |
JP2002505682A (ja) | 2002-02-19 |
EP1001769A4 (de) | 2000-05-24 |
WO1998058927A1 (en) | 1998-12-30 |
HUP0002521A3 (en) | 2002-04-29 |
CA2294606A1 (en) | 1998-12-30 |
AU3574097A (en) | 1999-01-04 |
DE69713526D1 (de) | 2002-07-25 |
ATE219363T1 (de) | 2002-07-15 |
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