HUP0002521A3 - Onium salts of paclitaxel, process for producing them and medicaments comprising the same - Google Patents
Onium salts of paclitaxel, process for producing them and medicaments comprising the sameInfo
- Publication number
- HUP0002521A3 HUP0002521A3 HU0002521A HUP0002521A HUP0002521A3 HU P0002521 A3 HUP0002521 A3 HU P0002521A3 HU 0002521 A HU0002521 A HU 0002521A HU P0002521 A HUP0002521 A HU P0002521A HU P0002521 A3 HUP0002521 A3 HU P0002521A3
- Authority
- HU
- Hungary
- Prior art keywords
- paclitaxel
- medicaments
- producing
- same
- onium salts
- Prior art date
Links
- 229930012538 Paclitaxel Natural products 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229960001592 paclitaxel Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical class O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1997/010746 WO1998058927A1 (en) | 1997-06-20 | 1997-06-20 | Soluble prodrugs of paclitaxel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0002521A2 HUP0002521A2 (hu) | 2001-06-28 |
| HUP0002521A3 true HUP0002521A3 (en) | 2002-04-29 |
Family
ID=22261122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0002521A HUP0002521A3 (en) | 1997-06-20 | 1997-06-20 | Onium salts of paclitaxel, process for producing them and medicaments comprising the same |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1001769B1 (hu) |
| JP (1) | JP2002505682A (hu) |
| AT (1) | ATE219363T1 (hu) |
| AU (1) | AU3574097A (hu) |
| CA (1) | CA2294606A1 (hu) |
| DE (1) | DE69713526D1 (hu) |
| HU (1) | HUP0002521A3 (hu) |
| IL (1) | IL133585A0 (hu) |
| SK (1) | SK182599A3 (hu) |
| WO (1) | WO1998058927A1 (hu) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003524624A (ja) * | 1999-04-09 | 2003-08-19 | ジェシー エル エス オウ | 治療薬の組織への送達を高める方法及び組成物 |
| US6713454B1 (en) | 1999-09-13 | 2004-03-30 | Nobex Corporation | Prodrugs of etoposide and etoposide analogs |
| US6541508B2 (en) | 1999-09-13 | 2003-04-01 | Nobex Corporation | Taxane prodrugs |
| US6380405B1 (en) | 1999-09-13 | 2002-04-30 | Nobex Corporation | Taxane prodrugs |
| US6638906B1 (en) | 1999-12-13 | 2003-10-28 | Nobex Corporation | Amphiphilic polymers and polypeptide conjugates comprising same |
| US7115565B2 (en) | 2001-01-18 | 2006-10-03 | Pharmacia & Upjohn Company | Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability |
| MXPA03006404A (es) * | 2001-01-18 | 2004-12-02 | Upjohn Co | Composiciones quimioterapeuticas de microemulsion de paclitaxel con biodisponibilidad oral mejorada. |
| US7351542B2 (en) | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
| EP2390262A1 (en) | 2003-05-16 | 2011-11-30 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
| US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| WO2006089218A2 (en) | 2005-02-17 | 2006-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for modulating angiogenesis |
| JP5523313B2 (ja) | 2007-07-03 | 2014-06-18 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用 |
| WO2009143454A2 (en) | 2008-05-22 | 2009-11-26 | Kereos, Inc. | Combination antitumor therapy |
| WO2010005850A1 (en) | 2008-07-08 | 2010-01-14 | The J. David Gladstone Institutes | Methods and compositions for modulating angiogenesis |
| EP2693876B1 (en) * | 2011-04-08 | 2020-01-15 | Sphaera Pharma Pte. Ltd | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds |
| IN2015DN00552A (hu) | 2012-07-19 | 2015-06-26 | Redwood Bioscience Inc | |
| EP2916835A4 (en) | 2012-11-12 | 2016-07-27 | Redwood Bioscience Inc | COMPOUNDS AND METHOD FOR PRODUCING A CONJUGATE |
| PT3613439T (pt) | 2013-02-15 | 2021-05-12 | Univ California | Recetor de antigénio quimérico e métodos de utilização do mesmo |
| US9670162B2 (en) | 2013-03-14 | 2017-06-06 | The Board Of Trustees Of The Leland Stanford Junio | Mitochondrial aldehyde dehyrogenase-2 modulators and methods of use thereof |
| AU2014354643B2 (en) | 2013-11-27 | 2020-03-05 | Redwood Bioscience, Inc. | Hydrazinyl-pyrrolo compounds and methods for producing a conjugate |
| CA2940269C (en) | 2014-02-19 | 2022-08-16 | Aviv Therapeutics, Inc. | Mitochondrial aldehyde dehydrogenase 2 (aldh2) binding polycyclic amides and their use for the treatment of cancer |
| US10654875B2 (en) | 2015-11-12 | 2020-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery |
| EP3377523A4 (en) | 2015-11-19 | 2019-06-19 | The Regents of The University of California | IMMUNITY CELL RECEIVERS REPRESSIBLE UNDER CONDITIONS AND METHODS OF USING THE SAME |
| EP3231421A1 (en) | 2016-04-11 | 2017-10-18 | Greenaltech, S.L. | Uses of a carotenoid in the treatment or prevention of stress induced conditions |
| WO2017189432A1 (en) | 2016-04-26 | 2017-11-02 | R.P. Scherer Technologies, Llc | Antibody conjugates and methods of making and using the same |
| UA123020C2 (uk) | 2016-06-01 | 2021-02-03 | Сервьє Айпі Юкей Лімітед | Склади поліалкіленоксид-аспарагінази та способи їхнього виготовлення й використання |
| KR20190130559A (ko) | 2017-01-18 | 2019-11-22 | 에프1 온콜로지, 인코포레이티드 | Axl 또는 ror2에 대한 키메라 항원 수용체 및 이의 사용 방법 |
| EP3388082A1 (en) | 2017-04-13 | 2018-10-17 | Galera Labs, LLC | Combination cancer immunotherapy with pentaaza macrocyclic ring complex |
| AU2019215032A1 (en) | 2018-01-31 | 2020-09-10 | Board Of Regents Of The University Of Texas System | Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent |
| CN112368011A (zh) | 2018-04-11 | 2021-02-12 | 俄亥俄州创新基金会 | 缓释微粒用于眼用药物递送的方法和组合物 |
| JP2021530507A (ja) | 2018-07-18 | 2021-11-11 | マンザニータ ファーマシューティカルズ，インク． | 神経細胞に抗がん剤を送達するためのコンジュゲート、その使用方法及び製造方法 |
| MX2021012003A (es) | 2019-04-02 | 2021-11-04 | Kenjockety Biotechnology Inc | Anticuerpos multiespecificos contra antigeno de cancer de la bomba de eflujo y composiciones, reactivos, kits y metodos relacionados con los mismos. |
| EP4097134A1 (en) | 2020-01-29 | 2022-12-07 | Kenjockety Biotechnology, Inc. | Anti-mdr1 antibodies and uses thereof |
| CN116323662A (zh) | 2020-06-04 | 2023-06-23 | 肯乔克蒂生物技术股份有限公司 | 抗abcg2抗体及其用途 |
| WO2021247423A1 (en) | 2020-06-04 | 2021-12-09 | Kenjockety Biotechnology, Inc. | Abcg2 efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto |
| CN116490522A (zh) | 2020-09-02 | 2023-07-25 | 肯乔克蒂生物技术股份有限公司 | 抗abcc1抗体及其应用 |
| CA3203652A1 (en) | 2020-11-13 | 2022-05-19 | William Robert ARATHOON | Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof |
| WO2023114658A1 (en) | 2021-12-13 | 2023-06-22 | Kenjockety Biotechnology, Inc. | Anti-abcb1 antibodies |
| WO2023159220A1 (en) | 2022-02-18 | 2023-08-24 | Kenjockety Biotechnology, Inc. | Anti-cd47 antibodies |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997015571A1 (en) * | 1995-10-27 | 1997-05-01 | The Scripps Research Institute | Method for treating cancer using taxoid onium salt prodrugs |
| CN1550231A (zh) * | 1997-05-27 | 2004-12-01 | �Ϳˡ�ŵ��ҩ������˾ | 给予病人口服紫杉烷类药物的方法和组合物 |
-
1997
- 1997-06-20 HU HU0002521A patent/HUP0002521A3/hu unknown
- 1997-06-20 SK SK1825-99A patent/SK182599A3/sk unknown
- 1997-06-20 DE DE69713526T patent/DE69713526D1/de not_active Expired - Lifetime
- 1997-06-20 JP JP50434699A patent/JP2002505682A/ja not_active Ceased
- 1997-06-20 CA CA002294606A patent/CA2294606A1/en not_active Abandoned
- 1997-06-20 AT AT97932226T patent/ATE219363T1/de not_active IP Right Cessation
- 1997-06-20 AU AU35740/97A patent/AU3574097A/en not_active Abandoned
- 1997-06-20 WO PCT/US1997/010746 patent/WO1998058927A1/en not_active Application Discontinuation
- 1997-06-20 EP EP97932226A patent/EP1001769B1/en not_active Expired - Lifetime
- 1997-06-20 IL IL13358597A patent/IL133585A0/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE219363T1 (de) | 2002-07-15 |
| CA2294606A1 (en) | 1998-12-30 |
| IL133585A0 (en) | 2001-04-30 |
| SK182599A3 (en) | 2000-07-11 |
| WO1998058927A1 (en) | 1998-12-30 |
| AU3574097A (en) | 1999-01-04 |
| EP1001769B1 (en) | 2002-06-19 |
| DE69713526D1 (de) | 2002-07-25 |
| HUP0002521A2 (hu) | 2001-06-28 |
| JP2002505682A (ja) | 2002-02-19 |
| EP1001769A4 (en) | 2000-05-24 |
| EP1001769A1 (en) | 2000-05-24 |
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