AU6926496A - New cyclic guanidines, process for preparing the same and medicaments - Google Patents

New cyclic guanidines, process for preparing the same and medicaments

Info

Publication number
AU6926496A
AU6926496A AU69264/96A AU6926496A AU6926496A AU 6926496 A AU6926496 A AU 6926496A AU 69264/96 A AU69264/96 A AU 69264/96A AU 6926496 A AU6926496 A AU 6926496A AU 6926496 A AU6926496 A AU 6926496A
Authority
AU
Australia
Prior art keywords
medicaments
preparing
same
new cyclic
cyclic guanidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU69264/96A
Inventor
Frank Grams
Ralf Kucznierz
Herbert Leinert
Karlheinz Stegmeier
Wolfgang Von Der Saal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of AU6926496A publication Critical patent/AU6926496A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU69264/96A 1995-08-23 1996-08-21 New cyclic guanidines, process for preparing the same and medicaments Abandoned AU6926496A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19530996A DE19530996A1 (en) 1995-08-23 1995-08-23 Cyclic guanidines, process for their preparation and pharmaceuticals
DE19530996 1995-08-23
PCT/EP1996/003679 WO1997008165A1 (en) 1995-08-23 1996-08-21 New cyclic guanidines, process for preparing the same and medicaments

Publications (1)

Publication Number Publication Date
AU6926496A true AU6926496A (en) 1997-03-19

Family

ID=7770182

Family Applications (1)

Application Number Title Priority Date Filing Date
AU69264/96A Abandoned AU6926496A (en) 1995-08-23 1996-08-21 New cyclic guanidines, process for preparing the same and medicaments

Country Status (6)

Country Link
EP (1) EP0846115A1 (en)
JP (1) JPH11511445A (en)
AU (1) AU6926496A (en)
CA (1) CA2229903A1 (en)
DE (1) DE19530996A1 (en)
WO (1) WO1997008165A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA985247B (en) * 1997-06-19 1999-12-17 Du Pont Merck Pharma Guanidine mimics as factor Xa inhibitors.
ATE293599T1 (en) 1997-12-24 2005-05-15 Aventis Pharma Gmbh INDOLE DERIVATIVES AS FACTOR XA INHIBITORS
EP0937723A1 (en) * 1998-02-18 1999-08-25 Roche Diagnostics GmbH Novel sulfonamides, process for their preparation and medicaments containing them
EP1070714B1 (en) * 1998-04-10 2004-08-04 Japan Tobacco Inc. Amidine compounds
DE19835950A1 (en) * 1998-08-08 2000-02-10 Merck Patent Gmbh Piperazinone derivatives
DE19839499A1 (en) * 1998-08-29 2000-03-02 Merck Patent Gmbh 2-oxo-2H-quinoline derivatives
WO2001056989A2 (en) * 2000-02-01 2001-08-09 Cor Therapeutics, Inc. Inhibitors of factor xa
DE10027024A1 (en) * 2000-05-31 2001-12-06 Merck Patent Gmbh Carbamic acid ester
DE10112768A1 (en) * 2001-03-16 2002-09-19 Merck Patent Gmbh New heterocyclic-substituted phenyl compounds, are Factor Xa and Factor VIIa inhibitors useful e.g. for treating thrombosis, myocardial infarction, inflammation, restenosis or tumor diseases
DE10139060A1 (en) 2001-08-08 2003-02-20 Merck Patent Gmbh New bicyclic benzene derivatives useful as factor Xa and VIIa inhibitors, e.g. for treating thrombosis, myocardial infarct, arteriosclerosis, inflammation, stroke, angina, restenosis and tumors
DK1569912T3 (en) 2002-12-03 2015-06-29 Pharmacyclics Inc 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors.
MXPA05006567A (en) 2002-12-20 2005-08-16 Glaxo Group Ltd BENZO aC¦ D!AZEPINE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS.
DE10302500A1 (en) 2003-01-23 2004-07-29 Merck Patent Gmbh New carboxamide derivatives useful as factor Xa or VIIa inhibitors e.g. for treating thrombosis, myocardial infarction, arteriosclerosis, inflammation, stroke and angina
DE10308907A1 (en) 2003-02-28 2004-09-09 Merck Patent Gmbh Ethynylderivate
EP2311810A4 (en) * 2008-07-11 2012-04-04 Ajinomoto Kk Amidine derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4127404A1 (en) * 1991-08-19 1993-02-25 Thomae Gmbh Dr K CYCLIC IMINODERIVATES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.

Also Published As

Publication number Publication date
DE19530996A1 (en) 1997-02-27
CA2229903A1 (en) 1997-03-06
WO1997008165A1 (en) 1997-03-06
EP0846115A1 (en) 1998-06-10
JPH11511445A (en) 1999-10-05

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