IL132966A0 - Method and system for detecting oligonucleotides in a sample - Google Patents
Method and system for detecting oligonucleotides in a sampleInfo
- Publication number
- IL132966A0 IL132966A0 IL13296699A IL13296699A IL132966A0 IL 132966 A0 IL132966 A0 IL 132966A0 IL 13296699 A IL13296699 A IL 13296699A IL 13296699 A IL13296699 A IL 13296699A IL 132966 A0 IL132966 A0 IL 132966A0
- Authority
- IL
- Israel
- Prior art keywords
- oligonucleotides
- sample
- target
- verification
- sensing interface
- Prior art date
Links
- 108091034117 Oligonucleotide Proteins 0.000 title abstract 12
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 title abstract 9
- 238000000034 method Methods 0.000 title abstract 3
- 238000012795 verification Methods 0.000 abstract 4
- 239000002773 nucleotide Substances 0.000 abstract 3
- 125000003729 nucleotide group Chemical group 0.000 abstract 3
- 230000000295 complement effect Effects 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6825—Nucleic acid detection involving sensors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL13296699A IL132966A0 (en) | 1998-12-01 | 1999-11-16 | Method and system for detecting oligonucleotides in a sample |
| EP99973075A EP1135533B1 (de) | 1998-12-01 | 1999-12-01 | Verfahren und system zur erkennung von oligonukleotiden in einer probe |
| CA002353562A CA2353562A1 (en) | 1998-12-01 | 1999-12-01 | Method and system for detecting oligonucleotides in a sample |
| DE69916650T DE69916650T2 (de) | 1998-12-01 | 1999-12-01 | Verfahren und system zur erkennung von oligonukleotiden in einer probe |
| AT99973075T ATE264923T1 (de) | 1998-12-01 | 1999-12-01 | Verfahren und system zur erkennung von oligonukleotiden in einer probe |
| PCT/IL1999/000649 WO2000032813A1 (en) | 1998-12-01 | 1999-12-01 | Method and system for detecting oligonucleotides in a sample |
| AU14074/00A AU770025B2 (en) | 1998-12-01 | 1999-12-01 | Method and system for detecting oligonucleotides in a sample |
| JP2000585444A JP2002531100A (ja) | 1998-12-01 | 1999-12-01 | 試料中のオリゴヌクレオチドの検出のための方法およびシステム |
| ES99973075T ES2221488T3 (es) | 1998-12-01 | 1999-12-01 | Metodo y sistema para detectar oligonucleotidos en una muestra. |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL12734698A IL127346A (en) | 1998-12-01 | 1998-12-01 | Method and system for detecting oligonucleotides in a sample |
| IL13296699A IL132966A0 (en) | 1998-12-01 | 1999-11-16 | Method and system for detecting oligonucleotides in a sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL132966A0 true IL132966A0 (en) | 2001-03-19 |
Family
ID=26323752
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13296699A IL132966A0 (en) | 1998-12-01 | 1999-11-16 | Method and system for detecting oligonucleotides in a sample |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1135533B1 (de) |
| JP (1) | JP2002531100A (de) |
| AT (1) | ATE264923T1 (de) |
| AU (1) | AU770025B2 (de) |
| CA (1) | CA2353562A1 (de) |
| DE (1) | DE69916650T2 (de) |
| ES (1) | ES2221488T3 (de) |
| IL (1) | IL132966A0 (de) |
| WO (1) | WO2000032813A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1409728A2 (de) * | 2001-04-09 | 2004-04-21 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Nicht-enzymatischer liposomen-gebundener, aus einer dichtgepackten elektrodenanordnung bestehender test (nel-ela) zur detektion und qantifizierung von nukleinsäuren |
| GB0205455D0 (en) | 2002-03-07 | 2002-04-24 | Molecular Sensing Plc | Nucleic acid probes, their synthesis and use |
| WO2003096014A2 (en) * | 2002-05-08 | 2003-11-20 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Magneto-controlled method and system for determining an analyte in a liquid medium |
| EP1445609B1 (de) | 2002-08-23 | 2006-11-22 | Kabushiki Kaisha Toshiba | Basensequenzierungselektroden, Basensequenzierungsvorrichtung und Basensequenzierungsverfahren |
| DE10256898B4 (de) * | 2002-11-29 | 2006-01-12 | Senslab-Gesellschaft Zur Entwicklung Und Herstellung Bioelektrochemischer Sensoren Mbh | Elektrochemischer Nachweis von Nukleinsäuren |
| WO2004060350A1 (en) * | 2003-01-06 | 2004-07-22 | Bioinvent International Ab | Immobilisation of dna-labelled lipid vesicles on dna arrays |
| JPWO2006033400A1 (ja) * | 2004-09-22 | 2008-05-15 | ダイキン工業株式会社 | Ｄｎａ検出方法及びレポータプローブ |
| JP4561451B2 (ja) * | 2005-04-15 | 2010-10-13 | セイコーエプソン株式会社 | 多型検出方法および多型検出用キット |
| JP4561478B2 (ja) * | 2005-05-26 | 2010-10-13 | セイコーエプソン株式会社 | 多型検出方法、多型検出用キット |
| DE102006003603B4 (de) * | 2006-01-25 | 2010-02-04 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vernetzbare multifunktionelle Träger für (niedermolekulare) Liganden und deren Anwendung in der Analytik sowie Verfahren zu deren Herstellung und Vernetzung |
| US8153780B2 (en) | 2007-02-06 | 2012-04-10 | Atonomics A/S | Reporter unit for detection of target molecules using polymerisable substrate |
| CN101241097B (zh) * | 2007-09-18 | 2011-08-03 | 中国科学院上海应用物理研究所 | 一种采用茎环结构检测探针的电化学dna检测方法及其试剂盒 |
| DE102010000906B4 (de) * | 2009-01-22 | 2012-07-12 | RUHR-UNIVERSITäT BOCHUM | Konjugate für den Nachweis doppelsträngiger Nukleinsäuren |
| JP2013513790A (ja) * | 2009-12-09 | 2013-04-22 | アイティーアイ・スコットランド・リミテッド | 検体の検出 |
| CN104698043A (zh) * | 2013-12-09 | 2015-06-10 | 重庆医科大学 | 检测大肠杆菌的dna电化学生物传感器及其制备方法 |
| WO2019026517A1 (ja) * | 2017-07-31 | 2019-02-07 | 国立大学法人大阪大学 | 溶液中に存在する対象物質の検出方法および検出するためのシステム |
| CN111044580B (zh) * | 2019-12-20 | 2021-10-01 | 中国农业大学 | 一种快速实时监测淡水鱼腌制程度的方法 |
| JP7801754B2 (ja) * | 2022-02-16 | 2026-01-19 | 株式会社エヌエフホールディングス | 被験検体中の目的核酸配列を測定するための測定方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5695926A (en) * | 1990-06-11 | 1997-12-09 | Bio Merieux | Sandwich hybridization assays using very short capture probes noncovalently bound to a hydrophobic support |
| US5474895A (en) * | 1990-11-14 | 1995-12-12 | Siska Diagnostics Inc. | Non-isotopic detection of nucleic acids using a polystyrene support-based sandwich hybridization assay and compositions useful therefor |
-
1999
- 1999-11-16 IL IL13296699A patent/IL132966A0/xx not_active IP Right Cessation
- 1999-12-01 AT AT99973075T patent/ATE264923T1/de not_active IP Right Cessation
- 1999-12-01 DE DE69916650T patent/DE69916650T2/de not_active Expired - Fee Related
- 1999-12-01 JP JP2000585444A patent/JP2002531100A/ja active Pending
- 1999-12-01 EP EP99973075A patent/EP1135533B1/de not_active Expired - Lifetime
- 1999-12-01 AU AU14074/00A patent/AU770025B2/en not_active Ceased
- 1999-12-01 WO PCT/IL1999/000649 patent/WO2000032813A1/en not_active Ceased
- 1999-12-01 CA CA002353562A patent/CA2353562A1/en not_active Abandoned
- 1999-12-01 ES ES99973075T patent/ES2221488T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69916650T2 (de) | 2005-04-21 |
| EP1135533A1 (de) | 2001-09-26 |
| CA2353562A1 (en) | 2000-06-08 |
| WO2000032813A1 (en) | 2000-06-08 |
| ATE264923T1 (de) | 2004-05-15 |
| ES2221488T3 (es) | 2004-12-16 |
| AU1407400A (en) | 2000-06-19 |
| AU770025B2 (en) | 2004-02-12 |
| JP2002531100A (ja) | 2002-09-24 |
| DE69916650D1 (de) | 2004-05-27 |
| EP1135533B1 (de) | 2004-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |