IL132615A0 - Pyrrolidine carboxylic acid derivatives as endothelin antagonists - Google Patents

Pyrrolidine carboxylic acid derivatives as endothelin antagonists

Info

Publication number
IL132615A0
IL132615A0 IL13261598A IL13261598A IL132615A0 IL 132615 A0 IL132615 A0 IL 132615A0 IL 13261598 A IL13261598 A IL 13261598A IL 13261598 A IL13261598 A IL 13261598A IL 132615 A0 IL132615 A0 IL 132615A0
Authority
IL
Israel
Prior art keywords
carboxylic acid
acid derivatives
endothelin antagonists
pyrrolidine carboxylic
pyrrolidine
Prior art date
Application number
IL13261598A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/087,178 external-priority patent/US6124341A/en
Application filed by Abbott Lab filed Critical Abbott Lab
Priority claimed from PCT/US1998/011821 external-priority patent/WO1998057933A1/en
Publication of IL132615A0 publication Critical patent/IL132615A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13261598A 1997-06-17 1998-06-08 Pyrrolidine carboxylic acid derivatives as endothelin antagonists IL132615A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87718797A 1997-06-17 1997-06-17
US09/087,178 US6124341A (en) 1996-02-13 1998-05-29 Endothelin antagonists
PCT/US1998/011821 WO1998057933A1 (en) 1997-06-17 1998-06-08 Pyrrolidine carboxylic acid derivatives as endothelin antagonists

Publications (1)

Publication Number Publication Date
IL132615A0 true IL132615A0 (en) 2001-03-19

Family

ID=26776689

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13261598A IL132615A0 (en) 1997-06-17 1998-06-08 Pyrrolidine carboxylic acid derivatives as endothelin antagonists

Country Status (7)

Country Link
EP (1) EP0991620A1 (xx)
KR (1) KR20010013954A (xx)
CN (1) CN1265097A (xx)
BR (1) BR9810031A (xx)
CA (1) CA2292604A1 (xx)
IL (1) IL132615A0 (xx)
SK (1) SK170699A3 (xx)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108929258A (zh) * 2018-07-09 2018-12-04 张立国 一种Rho激酶抑制剂及其在癌症治疗中的应用
CN108569990A (zh) * 2018-07-09 2018-09-25 张立国 多取代吡咯烷衍生物及其作为Rho激酶抑制剂在癌症中的应用

Also Published As

Publication number Publication date
CN1265097A (zh) 2000-08-30
CA2292604A1 (en) 1998-12-23
BR9810031A (pt) 2000-09-12
SK170699A3 (en) 2000-05-16
EP0991620A1 (en) 2000-04-12
KR20010013954A (ko) 2001-02-26

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