IL132584A0 - Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor - Google Patents

Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor

Info

Publication number
IL132584A0
IL132584A0 IL13258498A IL13258498A IL132584A0 IL 132584 A0 IL132584 A0 IL 132584A0 IL 13258498 A IL13258498 A IL 13258498A IL 13258498 A IL13258498 A IL 13258498A IL 132584 A0 IL132584 A0 IL 132584A0
Authority
IL
Israel
Prior art keywords
isolation
stem cells
intermediate precursor
neuroepithelial stem
lineage restricted
Prior art date
Application number
IL13258498A
Other languages
English (en)
Original Assignee
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utah Res Found filed Critical Univ Utah Res Found
Publication of IL132584A0 publication Critical patent/IL132584A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0661Smooth muscle cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0618Cells of the nervous system
    • C12N5/0623Stem cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/113Acidic fibroblast growth factor (aFGF, FGF-1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/115Basic fibroblast growth factor (bFGF, FGF-2)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/135Platelet-derived growth factor [PDGF]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30Hormones
    • C12N2501/38Hormones with nuclear receptors
    • C12N2501/385Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/08Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from cells of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Rheumatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IL13258498A 1997-05-07 1998-05-07 Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor IL132584A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/852,744 US6361996B1 (en) 1997-05-07 1997-05-07 Neuroepithelial stem cells and glial-restricted intermediate precursors
US09/073,881 US6830927B2 (en) 1997-05-07 1998-05-06 Common neural progenitor for the CNS and PNS
PCT/US1998/009630 WO1998050526A1 (en) 1997-05-07 1998-05-07 Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor
US10/025,333 US7037720B2 (en) 1997-05-07 2001-12-19 Neuroepithelial stem cells and glial-restricted intermediate precursors

Publications (1)

Publication Number Publication Date
IL132584A0 true IL132584A0 (en) 2001-03-19

Family

ID=37057261

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13258498A IL132584A0 (en) 1997-05-07 1998-05-07 Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor

Country Status (7)

Country Link
US (5) US6361996B1 (enExample)
EP (1) EP0983344A4 (enExample)
JP (1) JP2002513291A (enExample)
AU (1) AU751581C (enExample)
CA (1) CA2289021C (enExample)
IL (1) IL132584A0 (enExample)
WO (1) WO1998050526A1 (enExample)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263402B1 (en) * 1998-10-19 2012-09-11 Cornell Research Foundation, Inc. Method for isolating and purifying oligodendrocytes and oligodendrocyte progenitor cells
US7410798B2 (en) 2001-01-10 2008-08-12 Geron Corporation Culture system for rapid expansion of human embryonic stem cells
US6667176B1 (en) 2000-01-11 2003-12-23 Geron Corporation cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells
US20050042749A1 (en) 2001-05-16 2005-02-24 Carpenter Melissa K. Dopaminergic neurons and proliferation-competent precursor cells for treating Parkinson's disease
AU2001263199B2 (en) 2000-05-17 2004-09-16 Asterias Biotherapeutics, Inc. Neural progenitor cell populations
US7250294B2 (en) 2000-05-17 2007-07-31 Geron Corporation Screening small molecule drugs using neural cells differentiated from human embryonic stem cells
US6897061B1 (en) * 2000-06-16 2005-05-24 Spinal Cord Society Transdifferentiation of glial cells
CA2476376C (en) 2002-02-15 2014-10-21 Cornell Research Foundation, Inc. Myelination of congenitally dysmyelinated forebrains using oligodendrocyte progenitor cells
US7207743B2 (en) * 2002-05-28 2007-04-24 Polivka Parking Solutions Llc Method and apparatus for constructing an automotive vehicle parking lot
US7285415B2 (en) 2002-07-11 2007-10-23 The Regents Of The University Of California Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
US20050101014A1 (en) 2002-07-11 2005-05-12 Keirstead Hans S. Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury
AR046076A1 (es) * 2003-07-18 2005-11-23 Otsuka Pharma Co Ltd Procedimiento para obtener una poblacion homogenea de celulas precursoras de oligodendrocitos y poblacion obtenida
EP1682075A4 (en) * 2003-11-07 2009-12-09 Univ Florida BREEDING AND DIFFERENTIATION OF NEURAL CREATOR CELLS
US8147806B2 (en) 2004-01-16 2012-04-03 Carnegie Mellon University Cellular labeling for nuclear magnetic resonance techniques
CA2569978C (en) * 2004-06-09 2017-06-06 The University Court Of The University Of Edinburgh Neural stem cells
MX2007008668A (es) * 2005-01-19 2008-02-11 Fidia Advanced Biopolymers Srl Derivado de acido hialuronico y celulas germinales neurales para la regeneracion de una lesion de medula espinal o de una transeccion de nervio periferico.
US7803364B2 (en) 2005-11-17 2010-09-28 The Cleveland Clinic Foundation Multipotent neural stem cells
JP2009533684A (ja) * 2006-04-14 2009-09-17 カーネギー・メロン・ユニバーシティ 核磁気共鳴技術のための細胞標識及び定量
US20070258886A1 (en) * 2006-04-14 2007-11-08 Celsense Inc. Methods for assessing cell labeling
EP2054506A1 (en) 2006-08-15 2009-05-06 Agency for Science, Technology and Research Mesenchymal stem cell conditioned medium
US7927416B2 (en) 2006-10-31 2011-04-19 Sensient Colors Inc. Modified pigments and methods for making and using the same
WO2008131004A1 (en) * 2007-04-17 2008-10-30 University Of Rochester Telencephalic glial-restricted cell populations and related compositions and methods
AU2008275578B2 (en) * 2007-07-10 2014-04-10 Carnegie Mellon University Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques
WO2009026552A2 (en) 2007-08-23 2009-02-26 Sensient Colors Inc. Self-dispersed pigments and methods for making and using the same
EP2240536B1 (en) 2008-01-30 2019-09-04 Asterias Biotherapeutics, Inc. Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells
JP2011514169A (ja) 2008-03-17 2011-05-06 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ 幹細胞培養のためのマイクロキャリア
ES2611103T3 (es) * 2008-05-02 2017-05-04 Celsense Inc. Composiciones y métodos para producir emulsiones para técnicas de resonancia magnética nuclear y otras aplicaciones
CA2723382A1 (en) 2008-05-08 2009-11-12 University Of Rochester Treating myelin diseases with optimized cell preparations
US9688956B2 (en) 2008-06-05 2017-06-27 National Cheng Kung University Method for preserving proliferation and differentiation potential of mesenchymal stem cells
US8669048B2 (en) 2008-06-24 2014-03-11 Parkinson's Institute Pluripotent cell lines and methods of use thereof
WO2010068946A1 (en) * 2008-12-12 2010-06-17 Nova Southeastern University Methods of isolating and using stem cells
US20100158878A1 (en) 2008-12-23 2010-06-24 Alexandra Capela Target populations of oligodendrocyte precursor cells and methods of making and using same
US9221986B2 (en) 2009-04-07 2015-12-29 Sensient Colors Llc Self-dispersing particles and methods for making and using the same
SG10201404281YA (en) 2009-07-21 2014-09-26 Abt Holding Co Use of stem cells to reduce leukocyte extravasation
AU2010276201B2 (en) 2009-07-21 2013-10-17 Healios K.K. Use of stem cells to reduce leukocyte extravasation
JP6002581B2 (ja) * 2010-02-05 2016-10-05 オークランド ユニサービシズ リミテッドAuckland Uniservices Limited 細胞プログラミング
SG10201501402UA (en) 2010-02-25 2015-04-29 Abt Holding Co Modulation of macrophage activation
WO2012048298A2 (en) 2010-10-08 2012-04-12 Caridianbct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
US8433419B2 (en) 2010-10-13 2013-04-30 Cardiac Pacemakers, Inc. Method and apparatus for controlling neurostimulation according to physical state
KR102073530B1 (ko) 2011-06-06 2020-02-04 리제네시스 비브이비에이 중공 섬유 생물 반응기에서의 줄기 세포의 확장
EP2954046B1 (en) 2013-02-06 2025-10-15 University Of Rochester Induced pluripotent cell-derived oligodendrocyte progenitor cells for the treatment of myelin disorders
CA2907327C (en) 2013-03-15 2020-04-07 Wake Forest University Health Sciences Neural progenitor cell differentiation
AU2014250761B2 (en) 2013-04-12 2019-02-28 Robert J. Deans Improving organs for transplantation
AU2014266935B2 (en) 2013-04-30 2020-06-11 Katholieke Universiteit Leuven Cell therapy for myelodysplastic syndromes
WO2015073918A1 (en) 2013-11-16 2015-05-21 Terumo Bct, Inc. Expanding cells in a bioreactor
US9724432B2 (en) 2015-04-30 2017-08-08 University Of Rochester Non-human mammal model of human degenerative disorder, uses thereof, and method of treating human degenerative disorder
US11406721B2 (en) 2016-02-22 2022-08-09 The Regents Of The University Of California Compositions and methods for imaging cell populations
US11920155B2 (en) 2016-03-30 2024-03-05 Asterias Biotherapeutics, Inc. Oligodendrocyte progenitor cell compositions
MY192056A (en) * 2017-01-31 2022-07-25 Univ Osaka Method for controlling differentiation of pluripotent stem cells
CN110913689A (zh) 2017-05-10 2020-03-24 罗切斯特大学 治疗神经精神病症的方法
US12365872B2 (en) 2018-09-19 2025-07-22 Lineage Cell Therapeutics, Inc. Methods for differentiating pluripotent stem cells in dynamic suspension culture
US11603518B2 (en) 2019-01-23 2023-03-14 Asterias Biotherapeutics, Inc. Dorsally-derived oligodendrocyte progenitor cells from human pluripotent stem cells
EP4017508A1 (en) 2019-08-23 2022-06-29 Sana Biotechnology, Inc. Cd24 expressing cells and uses thereof
MX2022011831A (es) 2020-03-25 2023-01-04 Sana Biotechnology Inc Células neurales hipoinmunogénicas para el tratamiento de trastornos y afecciones neurológicas.
MX2023001831A (es) 2020-08-13 2023-06-29 Sana Biotechnology Inc Métodos de tratamiento de pacientes sensibilizados con células hipoinmunogénicas y métodos y composiciones asociados.
KR20240013135A (ko) 2021-05-27 2024-01-30 사나 바이오테크놀로지, 인크. 조작된 hla-e 또는 hla-g를 포함하는 저면역원성 세포
AU2022309875A1 (en) 2021-07-14 2024-01-25 Sana Biotechnology, Inc. Altered expression of y chromosome-linked antigens in hypoimmunogenic cells
EP4384598A1 (en) 2021-08-11 2024-06-19 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy to reduce complement-mediated inflammatory reactions
IL310702A (en) 2021-08-11 2024-04-01 Sana Biotechnology Inc Inducible systems for altering gene expression in hypoimmunogenic cells
EP4384544A1 (en) 2021-08-11 2024-06-19 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy
WO2023019225A2 (en) 2021-08-11 2023-02-16 Sana Biotechnology, Inc. Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions
WO2023183313A1 (en) 2022-03-22 2023-09-28 Sana Biotechnology, Inc. Engineering cells with a transgene in b2m or ciita locus and associated compositions and methods
WO2025054202A1 (en) 2023-09-05 2025-03-13 Sana Biotechnology, Inc. Method of screening a sample comprising a transgene with a unique barcode
WO2025151838A1 (en) 2024-01-12 2025-07-17 Sana Biotechnology, Inc. Safety switches to control in vitro and in vivo proliferation of cell therapy products

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411883A (en) * 1989-12-26 1995-05-02 Somatix Therapy Corporation Proliferated neuron progenitor cell product and process
US5589376A (en) 1992-07-27 1996-12-31 California Institute Of Technology Mammalian neural crest stem cells
AU678988B2 (en) * 1992-07-27 1997-06-19 California Institute Of Technology Mammalian multipotent neural stem cells
US5753506A (en) * 1996-05-23 1998-05-19 Cns Stem Cell Technology, Inc. Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals

Also Published As

Publication number Publication date
CA2289021C (en) 2013-07-09
WO1998050526A1 (en) 1998-11-12
US20020142460A1 (en) 2002-10-03
US20020045251A1 (en) 2002-04-18
US7037720B2 (en) 2006-05-02
US6830927B2 (en) 2004-12-14
AU751581C (en) 2003-06-19
US20100015702A1 (en) 2010-01-21
US6361996B1 (en) 2002-03-26
EP0983344A4 (en) 2000-09-27
US20060199264A1 (en) 2006-09-07
US7595194B2 (en) 2009-09-29
EP0983344A1 (en) 2000-03-08
AU751581B2 (en) 2002-08-22
AU7481198A (en) 1998-11-27
JP2002513291A (ja) 2002-05-08
CA2289021A1 (en) 1998-11-12

Similar Documents

Publication Publication Date Title
IL132584A0 (en) Generation characterization and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor
AU7813401A (en) Isolation and use of solid tumor stem cells
AU3032797A (en) Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity
GB9608540D0 (en) Isolation of enzymes
IL149043A0 (en) Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells
AU8122198A (en) Process for the preparation of methanol and hydrogen
SG67999A1 (en) Process for manufacture of mos gated device with self aligned cells
HU9900145D0 (en) Preparation of sterol and stanolesters
AU1478000A (en) (in utero) transplantation of human mesenchymal stem cells
AU2892997A (en) Pluripotent rabbit embryonic stem (es) cell lines and their use in the generation of chimeric rabbits
EP0923642A4 (en) ACTIVE SURVIVAL DOMAINS OF THE IGF-I RECEPTOR AND THEIR USE
AU3557597A (en) The isolation and culture of fetal cells from peripheral maternal blood
AU8140998A (en) Development and use of human pancreatic cell lines
IL146397A0 (en) Ex vivo expansion of mammalian hematopoietic stem cells
IL141585A (en) Numbering of video objects and cells
ZA989077B (en) Isolation of nutrient rich carotenoids and their formulations
AU2998300A (en) Genetically altered mesenchymal stem cells and methods of use thereof
AU1167797A (en) Layout and procedure of charging of batteries
PL337732A1 (en) Fertilising composition of controllable active ingredients release and method of obtaining same
AU3555297A (en) In vitro assay for carcinogens using phenotypic transformation of human cells
AU2002309073A1 (en) Generation, characterization, and isolation of neuroepithelial stem cells and lineage restricted intermediate precursor
IL129094A0 (en) Hematopoietic stem cells and methods for generating such cells
ZA964981B (en) Isolation of naturally occurring isoflavonone and some clinical uses thereof
AU5696299A (en) Isolation of natural l-beta-3-indolylalanine and enrichment of natural aliphaticamino acid mixtures with natural l-beta-3-indolylalanine
AU3594400A (en) Isolation of stem cells and methods of use thereof

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees