IL131419A0 - Polymorph of zopolrestat monohydrate - Google Patents
Polymorph of zopolrestat monohydrateInfo
- Publication number
- IL131419A0 IL131419A0 IL13141999A IL13141999A IL131419A0 IL 131419 A0 IL131419 A0 IL 131419A0 IL 13141999 A IL13141999 A IL 13141999A IL 13141999 A IL13141999 A IL 13141999A IL 131419 A0 IL131419 A0 IL 131419A0
- Authority
- IL
- Israel
- Prior art keywords
- polymorph
- zopolrestat monohydrate
- zopolrestat
- monohydrate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9747498P | 1998-08-21 | 1998-08-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL131419A0 true IL131419A0 (en) | 2001-01-28 |
Family
ID=22263562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13141999A IL131419A0 (en) | 1998-08-21 | 1999-08-16 | Polymorph of zopolrestat monohydrate |
Country Status (31)
Country | Link |
---|---|
US (1) | US6159976A (ko) |
EP (1) | EP0982306A3 (ko) |
JP (1) | JP2000072769A (ko) |
KR (1) | KR20000017411A (ko) |
CN (1) | CN1245804A (ko) |
AP (1) | AP9901662A0 (ko) |
AU (1) | AU4453299A (ko) |
BG (1) | BG103674A (ko) |
BR (1) | BR9903873A (ko) |
CA (1) | CA2280590A1 (ko) |
EA (1) | EA199900675A3 (ko) |
EE (1) | EE9900385A (ko) |
GT (1) | GT199900137A (ko) |
HR (1) | HRP990259A2 (ko) |
HU (1) | HUP9902783A3 (ko) |
ID (1) | ID23307A (ko) |
IL (1) | IL131419A0 (ko) |
IS (1) | IS5155A (ko) |
MA (1) | MA26678A1 (ko) |
NO (1) | NO994027L (ko) |
NZ (1) | NZ337363A (ko) |
OA (1) | OA11150A (ko) |
PA (1) | PA8480601A1 (ko) |
PE (1) | PE20000993A1 (ko) |
PL (1) | PL335016A1 (ko) |
SG (1) | SG83147A1 (ko) |
TN (1) | TNSN99159A1 (ko) |
TR (1) | TR199901996A2 (ko) |
UY (1) | UY25668A1 (ko) |
YU (1) | YU39899A (ko) |
ZA (1) | ZA995297B (ko) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5934206B2 (ja) | 2010-07-16 | 2016-06-15 | ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | アルドース還元酵素阻害剤および同使用方法 |
US8916563B2 (en) | 2010-07-16 | 2014-12-23 | The Trustees Of Columbia University In The City Of New York | Aldose reductase inhibitors and uses thereof |
US20140228319A1 (en) * | 2013-02-13 | 2014-08-14 | Banavara L. Mylari | Water soluble salts of aldose reductase inhibitors for treatment of diabetic complications |
IL304979A (en) | 2016-06-21 | 2023-10-01 | Univ Columbia | Aldose reductase inhibitors and methods of using them |
PT3658142T (pt) | 2017-07-28 | 2024-06-27 | Applied Therapeutics Inc | Composições e métodos para tratar galactosemia |
AU2020254610A1 (en) | 2019-04-01 | 2021-11-18 | Applied Therapeutics Inc. | Inhibitors of aldose reductase |
EP4125909A1 (en) | 2020-03-31 | 2023-02-08 | Applied Therapeutics Inc. | Aldose reductase inhibitors for the treatment of acute respiratory distress syndrome, acute lung inflammation/injury, cardiac injury and anti-viral therapy |
AU2021264454A1 (en) | 2020-05-01 | 2022-12-08 | Applied Therapeutics, Inc. | Aldose reductase inhibitors for treating sorbitol dehydrogenase deficiency |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4939140A (en) * | 1985-11-07 | 1990-07-03 | Pfizer Inc. | Heterocyclic oxophthalazinyl acetic acids |
US4748280A (en) * | 1985-11-07 | 1988-05-31 | Pfizer Inc. | Certain chlorination process for preparing 2-chloro-1,1,1-(C1 -C6) |
JPH0676391B2 (ja) * | 1987-06-09 | 1994-09-28 | フアイザー・インコーポレイテツド | ベンゾチアゾール等の複素環側鎖を有するオキソフタラジニル酢酸類の製造方法 |
US4868301A (en) * | 1987-06-09 | 1989-09-19 | Pfizer Inc. | Processes and intermediates for the preparation of oxophthalazinyl acetic acids having benzothiazole or other heterocyclic side chains |
US4904782A (en) * | 1988-02-29 | 1990-02-27 | Pfizer Inc. | Process for the production of phthalazineacetic acid ester derivatives and a novel intermediate |
US4954629A (en) * | 1989-05-11 | 1990-09-04 | Pfizer Inc. | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof |
WO1992003432A1 (en) * | 1990-08-28 | 1992-03-05 | Pfizer Inc. | 3-(5-trifluoromethylbenzothiazol-2-ylmethyl)-4-oxo-3h-phythalazin-1-ylacetic acid monohydrate |
US5391551A (en) * | 1993-05-10 | 1995-02-21 | Pfizer Inc. | Method of lowering blood lipid levels |
IL120264A0 (en) * | 1996-02-29 | 1997-06-10 | Pfizer | Method of reducing tissue damage associated with non-cardiac ischemia |
-
1999
- 1999-08-06 EP EP99306252A patent/EP0982306A3/en not_active Withdrawn
- 1999-08-13 US US09/374,729 patent/US6159976A/en not_active Expired - Fee Related
- 1999-08-16 IL IL13141999A patent/IL131419A0/xx unknown
- 1999-08-17 AU AU44532/99A patent/AU4453299A/en not_active Abandoned
- 1999-08-17 IS IS5155A patent/IS5155A/is unknown
- 1999-08-18 TN TNTNSN99159A patent/TNSN99159A1/fr unknown
- 1999-08-18 MA MA25738A patent/MA26678A1/fr unknown
- 1999-08-19 EE EEP199900385A patent/EE9900385A/xx unknown
- 1999-08-19 YU YU39899A patent/YU39899A/sh unknown
- 1999-08-19 OA OA9900185A patent/OA11150A/en unknown
- 1999-08-19 HU HU9902783A patent/HUP9902783A3/hu unknown
- 1999-08-19 SG SG9904131A patent/SG83147A1/en unknown
- 1999-08-19 UY UY25668A patent/UY25668A1/es not_active Application Discontinuation
- 1999-08-19 AP APAP/P/1999/001662A patent/AP9901662A0/en unknown
- 1999-08-19 CA CA002280590A patent/CA2280590A1/en not_active Abandoned
- 1999-08-19 GT GT199900137A patent/GT199900137A/es unknown
- 1999-08-19 ZA ZA9905297A patent/ZA995297B/xx unknown
- 1999-08-20 ID IDP990796A patent/ID23307A/id unknown
- 1999-08-20 KR KR1019990034527A patent/KR20000017411A/ko not_active Application Discontinuation
- 1999-08-20 PL PL99335016A patent/PL335016A1/xx not_active Application Discontinuation
- 1999-08-20 NO NO994027A patent/NO994027L/no not_active Application Discontinuation
- 1999-08-20 BG BG103674A patent/BG103674A/xx unknown
- 1999-08-20 PE PE1999000844A patent/PE20000993A1/es not_active Application Discontinuation
- 1999-08-20 BR BR9903873-0A patent/BR9903873A/pt not_active Application Discontinuation
- 1999-08-20 HR HR990259A patent/HRP990259A2/hr not_active Application Discontinuation
- 1999-08-20 TR TR1999/01996A patent/TR199901996A2/xx unknown
- 1999-08-20 NZ NZ337363A patent/NZ337363A/xx unknown
- 1999-08-20 EA EA199900675A patent/EA199900675A3/ru unknown
- 1999-08-20 PA PA19998480601A patent/PA8480601A1/es unknown
- 1999-08-23 JP JP11235855A patent/JP2000072769A/ja active Pending
- 1999-08-23 CN CN99118068A patent/CN1245804A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
SG83147A1 (en) | 2001-09-18 |
TNSN99159A1 (fr) | 2005-11-10 |
HUP9902783A2 (hu) | 2000-12-28 |
MA26678A1 (fr) | 2004-12-20 |
NO994027D0 (no) | 1999-08-20 |
PE20000993A1 (es) | 2000-10-04 |
PL335016A1 (en) | 2000-02-28 |
ZA995297B (en) | 2001-02-19 |
EE9900385A (et) | 2000-04-17 |
HUP9902783A3 (en) | 2001-01-29 |
AU4453299A (en) | 2000-03-09 |
KR20000017411A (ko) | 2000-03-25 |
NO994027L (no) | 2000-02-22 |
BG103674A (en) | 2000-03-31 |
BR9903873A (pt) | 2000-09-19 |
CA2280590A1 (en) | 2000-02-21 |
HRP990259A2 (en) | 2000-06-30 |
JP2000072769A (ja) | 2000-03-07 |
AP9901662A0 (en) | 1999-09-30 |
HU9902783D0 (en) | 1999-10-28 |
TR199901996A2 (xx) | 2000-03-21 |
EP0982306A2 (en) | 2000-03-01 |
EA199900675A3 (ru) | 2000-06-26 |
EP0982306A3 (en) | 2000-07-05 |
CN1245804A (zh) | 2000-03-01 |
IS5155A (is) | 2000-02-22 |
UY25668A1 (es) | 2001-08-27 |
YU39899A (sh) | 2002-12-10 |
US6159976A (en) | 2000-12-12 |
GT199900137A (es) | 2001-02-09 |
PA8480601A1 (es) | 2000-09-29 |
EA199900675A2 (ru) | 2000-02-28 |
ID23307A (id) | 2000-04-05 |
OA11150A (en) | 2003-04-16 |
NZ337363A (en) | 2001-01-26 |
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