IL130500A - Use of comt inhibitors for the manufacture of a medicament for the prevention of diabetic vascular dysfunctions - Google Patents
Use of comt inhibitors for the manufacture of a medicament for the prevention of diabetic vascular dysfunctionsInfo
- Publication number
- IL130500A IL130500A IL13050097A IL13050097A IL130500A IL 130500 A IL130500 A IL 130500A IL 13050097 A IL13050097 A IL 13050097A IL 13050097 A IL13050097 A IL 13050097A IL 130500 A IL130500 A IL 130500A
- Authority
- IL
- Israel
- Prior art keywords
- medicament
- prevention
- manufacture
- comt inhibitors
- diabetic vascular
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9626472.6A GB9626472D0 (en) | 1996-12-20 | 1996-12-20 | New use of comt inhibitors |
PCT/FI1997/000812 WO1998027973A1 (en) | 1996-12-20 | 1997-12-19 | Use of comt inhibitors for the manufacture of a medicament for the prevention of diabetic vascular dysfunctions |
Publications (2)
Publication Number | Publication Date |
---|---|
IL130500A0 IL130500A0 (en) | 2000-06-01 |
IL130500A true IL130500A (en) | 2003-02-12 |
Family
ID=10804746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL13050097A IL130500A (en) | 1996-12-20 | 1997-12-19 | Use of comt inhibitors for the manufacture of a medicament for the prevention of diabetic vascular dysfunctions |
Country Status (23)
Country | Link |
---|---|
US (1) | US6207706B1 (no) |
EP (1) | EP0964678B1 (no) |
JP (1) | JP2001507006A (no) |
KR (1) | KR20000057628A (no) |
AT (1) | ATE234613T1 (no) |
AU (1) | AU714086B2 (no) |
BG (1) | BG103491A (no) |
CA (1) | CA2275681A1 (no) |
CZ (1) | CZ291117B6 (no) |
DE (1) | DE69720064D1 (no) |
EA (1) | EA001673B1 (no) |
EE (1) | EE9700350A (no) |
GB (1) | GB9626472D0 (no) |
HU (1) | HUP0001097A3 (no) |
IL (1) | IL130500A (no) |
NO (1) | NO992985D0 (no) |
NZ (1) | NZ336043A (no) |
PL (1) | PL334093A1 (no) |
SK (1) | SK79999A3 (no) |
TR (1) | TR199901206T2 (no) |
WO (1) | WO1998027973A1 (no) |
YU (1) | YU28599A (no) |
ZA (1) | ZA9711468B (no) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI20000635A0 (fi) | 2000-03-17 | 2000-03-17 | Orion Yhtymae Oyj | COMT-inhibiittoreiden käyttö analgeettina |
FI20001593A (fi) | 2000-07-03 | 2002-01-04 | Orion Yhtymo Oyj | Comt-entsyymiõ inhiboivaa aktiivisuutta omaavia kumariinijohdannaisia |
FI20002044A0 (fi) | 2000-09-15 | 2000-09-15 | Orion Yhtymae Oyj | Comt-entsyymiä estäviä naftaleenijohdannaisia |
MY148644A (en) * | 2005-07-18 | 2013-05-15 | Orion Corp | New pharmaceutical compounds |
TWI638802B (zh) | 2012-05-24 | 2018-10-21 | 芬蘭商奧利安公司 | 兒茶酚o-甲基轉移酶活性抑制化合物 |
JP2021532133A (ja) | 2018-07-25 | 2021-11-25 | オリオン コーポレーション | 4,5−ジヒドロキシ−2−(4−メチルベンジル)イソフタロニトリル溶媒和物およびその結晶形 |
WO2020094928A1 (en) | 2018-11-09 | 2020-05-14 | Orion Corporation | Process for the preparation of 4,5-dihydroxy-2-(4-methylbenzyl)isophthalonitrile |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4672042A (en) | 1981-12-21 | 1987-06-09 | Orion Research Puerto Rico, Inc. | Method of and apparatus for chromatographic analysis |
DK175069B1 (da) | 1986-03-11 | 2004-05-24 | Hoffmann La Roche | Pyrocatecholderivater |
US5236952A (en) * | 1986-03-11 | 1993-08-17 | Hoffmann-La Roche Inc. | Catechol derivatives |
FI864875A0 (fi) | 1986-11-28 | 1986-11-28 | Orion Yhtymae Oy | Nya farmakologiskt aktiva foereningar, dessa innehaollande kompositioner samt foerfarande och mellanprodukter foer anvaendning vid framstaellning av dessa. |
YU213587A (en) | 1986-11-28 | 1989-06-30 | Orion Yhtymae Oy | Process for obtaining new pharmacologic active cateholic derivatives |
US5283352A (en) * | 1986-11-28 | 1994-02-01 | Orion-Yhtyma Oy | Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same |
US5489614A (en) | 1987-11-27 | 1996-02-06 | Orion-Yhtyma Oy | Catechol derivatives, their physiologically acceptable salts, esters and use |
MTP1031B (en) * | 1987-12-24 | 1990-10-04 | Orion Yhtymae Oy | New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters |
IL91382A (en) | 1988-09-01 | 1995-06-29 | Orion Yhtymae Oy | Dicitons are converted into alkanyl or ethylmethylene, through their preparation and pharmaceutical preparations containing them |
US5185370A (en) | 1988-09-01 | 1993-02-09 | Orion-Yhtyma Oy | Substituted β-diketones and their use |
GB8903130D0 (en) | 1989-02-11 | 1989-03-30 | Orion Yhtymae Oy | Substituted pyridazinones |
US5185332A (en) | 1989-02-11 | 1993-02-09 | Orion-Yhtyma Oy | Thiadiazines and pharmaceutical compositions thereof as well as method of use |
GB9510481D0 (en) | 1995-05-24 | 1995-07-19 | Orion Yhtymae Oy | New catechol derivatives |
-
1996
- 1996-12-20 GB GBGB9626472.6A patent/GB9626472D0/en active Pending
-
1997
- 1997-12-19 WO PCT/FI1997/000812 patent/WO1998027973A1/en not_active Application Discontinuation
- 1997-12-19 KR KR1019990705423A patent/KR20000057628A/ko not_active Application Discontinuation
- 1997-12-19 CZ CZ19992231A patent/CZ291117B6/cs not_active IP Right Cessation
- 1997-12-19 US US09/331,113 patent/US6207706B1/en not_active Expired - Fee Related
- 1997-12-19 AT AT97948919T patent/ATE234613T1/de not_active IP Right Cessation
- 1997-12-19 IL IL13050097A patent/IL130500A/xx not_active IP Right Cessation
- 1997-12-19 JP JP52844098A patent/JP2001507006A/ja active Pending
- 1997-12-19 ZA ZA9711468A patent/ZA9711468B/xx unknown
- 1997-12-19 EP EP97948919A patent/EP0964678B1/en not_active Expired - Lifetime
- 1997-12-19 SK SK799-99A patent/SK79999A3/sk unknown
- 1997-12-19 CA CA002275681A patent/CA2275681A1/en not_active Abandoned
- 1997-12-19 YU YU28599A patent/YU28599A/sh unknown
- 1997-12-19 TR TR1999/01206T patent/TR199901206T2/xx unknown
- 1997-12-19 PL PL97334093A patent/PL334093A1/xx unknown
- 1997-12-19 EA EA199900579A patent/EA001673B1/ru not_active IP Right Cessation
- 1997-12-19 EE EE9700350A patent/EE9700350A/xx unknown
- 1997-12-19 DE DE69720064T patent/DE69720064D1/de not_active Expired - Lifetime
- 1997-12-19 HU HU0001097A patent/HUP0001097A3/hu unknown
- 1997-12-19 NZ NZ336043A patent/NZ336043A/xx unknown
- 1997-12-19 AU AU78711/98A patent/AU714086B2/en not_active Ceased
-
1999
- 1999-06-14 BG BG103491A patent/BG103491A/bg unknown
- 1999-06-17 NO NO992985A patent/NO992985D0/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2275681A1 (en) | 1998-07-02 |
ATE234613T1 (de) | 2003-04-15 |
EP0964678B1 (en) | 2003-03-19 |
PL334093A1 (en) | 2000-01-31 |
NZ336043A (en) | 2000-12-22 |
CZ223199A3 (cs) | 1999-11-17 |
WO1998027973A1 (en) | 1998-07-02 |
TR199901206T2 (xx) | 1999-08-23 |
EA001673B1 (ru) | 2001-06-25 |
SK79999A3 (en) | 2000-05-16 |
EA199900579A1 (ru) | 1999-12-29 |
HUP0001097A2 (hu) | 2000-09-28 |
HUP0001097A3 (en) | 2003-05-28 |
NO992985L (no) | 1999-06-17 |
EP0964678A1 (en) | 1999-12-22 |
NO992985D0 (no) | 1999-06-17 |
EE9700350A (et) | 1998-10-15 |
DE69720064D1 (de) | 2003-04-24 |
IL130500A0 (en) | 2000-06-01 |
GB9626472D0 (en) | 1997-02-05 |
KR20000057628A (ko) | 2000-09-25 |
YU28599A (sh) | 2002-03-18 |
AU7871198A (en) | 1998-07-17 |
CZ291117B6 (cs) | 2002-12-11 |
JP2001507006A (ja) | 2001-05-29 |
BG103491A (bg) | 2000-04-28 |
US6207706B1 (en) | 2001-03-27 |
AU714086B2 (en) | 1999-12-16 |
ZA9711468B (en) | 1998-08-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9700538A (es) | Uso de droloxifeno y sus sales farmaceuticamente aceptables en la preparacion de remedios para las enfermedades cardiovasculares. | |
NZ515567A (en) | Method for treating chronic pain using MEK inhibitors | |
AU7321598A (en) | Use of cholinesterase inhibitors to treat disorders of attention | |
HUP9904221A3 (en) | Use of cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia for producing pharmaceutical compositions | |
NZ503233A (en) | Synergistic analgesic combination of opioid analgesic and COX-2 inhibitor | |
YU63699A (sh) | Preparati za tretiranje i prevenciju arterijske tromboze i korišćenje inhibitora faktora xa samog ili u kombinaciji sa plateletnim antiagregacionim agensom | |
YU82602A (sh) | Korišćenje il-18 inhibitora za lečenje i/ili prevenciju ateroskleroze | |
HK1068106A1 (en) | Use of sarp-1 for the treatment and/or prevention of scleroderma | |
AU2001246600A1 (en) | Use of comt inhibitors as analgesics | |
GB0020504D0 (en) | Therapeutic method | |
IL130500A0 (en) | Use of comt inhibitors for the manufacture of a medicament for the prevention of diabetic vascular dysfunctions | |
GB9521608D0 (en) | Pharmaceutical composition | |
IL124236A (en) | Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor | |
ZA923935B (en) | New 2-amino-5-cyano-1,4-dihydropyridines,processes for their preparation and their use in medicaments | |
ZA969586B (en) | The use of cholinesterase inhibitors in the treatment of xerostomia | |
SI1003554T1 (en) | Proton pump inhibitor in therapeutic combination with antibacterial substances | |
AU5434899A (en) | Cancer treatment | |
IL126158A0 (en) | Method for treating substance abuse | |
WO2002005796A3 (en) | Use of a spla2 inhibitor for the treatment of sepsis | |
HUP9903979A3 (en) | Use of nitric oxidesynthase inhibitors to treat or prevent type ii diabetes | |
ZA983753B (en) | Medicinal composition for treatment of burns, cuts and like wounds. | |
MY118982A (en) | Method of reducing tissue damage associated with ischemia | |
PL328949A1 (en) | Method of treatng excessive aggression | |
EP0810866A4 (en) | USE IN THE TREATMENT OF CANCERS OF ORGANOMETALLIC COMPOUNDS OF ACID-SENSITIVE TRANSITION METALS | |
BG102974A (en) | Ethene-containing solutions and their use in methods of treatment or prevention |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
RH1 | Patent not in force |