EA199900579A1 - Применение ингибиторов комт для производства лекарственного средства для профилактики сосудистых дисфункций при диабете - Google Patents

Применение ингибиторов комт для производства лекарственного средства для профилактики сосудистых дисфункций при диабете

Info

Publication number
EA199900579A1
EA199900579A1 EA199900579A EA199900579A EA199900579A1 EA 199900579 A1 EA199900579 A1 EA 199900579A1 EA 199900579 A EA199900579 A EA 199900579A EA 199900579 A EA199900579 A EA 199900579A EA 199900579 A1 EA199900579 A1 EA 199900579A1
Authority
EA
Eurasian Patent Office
Prior art keywords
diabetes
application
medicines
prevention
production
Prior art date
Application number
EA199900579A
Other languages
English (en)
Other versions
EA001673B1 (ru
Inventor
Анита Катарина Апериа
Инге-Бритт Ивонне Линден
Original Assignee
Орион-Ихтюмя Ойй
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Орион-Ихтюмя Ойй filed Critical Орион-Ихтюмя Ойй
Publication of EA199900579A1 publication Critical patent/EA199900579A1/ru
Publication of EA001673B1 publication Critical patent/EA001673B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

Настоящее изобретение относится к применению ингибиторов КОМТ для лечения сосудистых дисфункций при диабете.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900579A 1996-12-20 1997-12-19 Применение ингибиторов катехол-о-метилтрансферазы (комт) для производства лекарственного средства для профилактики сосудистых дисфункций при диабете EA001673B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9626472.6A GB9626472D0 (en) 1996-12-20 1996-12-20 New use of comt inhibitors
PCT/FI1997/000812 WO1998027973A1 (en) 1996-12-20 1997-12-19 Use of comt inhibitors for the manufacture of a medicament for the prevention of diabetic vascular dysfunctions

Publications (2)

Publication Number Publication Date
EA199900579A1 true EA199900579A1 (ru) 1999-12-29
EA001673B1 EA001673B1 (ru) 2001-06-25

Family

ID=10804746

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900579A EA001673B1 (ru) 1996-12-20 1997-12-19 Применение ингибиторов катехол-о-метилтрансферазы (комт) для производства лекарственного средства для профилактики сосудистых дисфункций при диабете

Country Status (23)

Country Link
US (1) US6207706B1 (ru)
EP (1) EP0964678B1 (ru)
JP (1) JP2001507006A (ru)
KR (1) KR20000057628A (ru)
AT (1) ATE234613T1 (ru)
AU (1) AU714086B2 (ru)
BG (1) BG103491A (ru)
CA (1) CA2275681A1 (ru)
CZ (1) CZ291117B6 (ru)
DE (1) DE69720064D1 (ru)
EA (1) EA001673B1 (ru)
EE (1) EE9700350A (ru)
GB (1) GB9626472D0 (ru)
HU (1) HUP0001097A3 (ru)
IL (1) IL130500A (ru)
NO (1) NO992985L (ru)
NZ (1) NZ336043A (ru)
PL (1) PL334093A1 (ru)
SK (1) SK79999A3 (ru)
TR (1) TR199901206T2 (ru)
WO (1) WO1998027973A1 (ru)
YU (1) YU28599A (ru)
ZA (1) ZA9711468B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI20000635A0 (fi) 2000-03-17 2000-03-17 Orion Yhtymae Oyj COMT-inhibiittoreiden käyttö analgeettina
FI20001593A (fi) 2000-07-03 2002-01-04 Orion Yhtymo Oyj Comt-entsyymiõ inhiboivaa aktiivisuutta omaavia kumariinijohdannaisia
FI20002044A0 (fi) 2000-09-15 2000-09-15 Orion Yhtymae Oyj Comt-entsyymiä estäviä naftaleenijohdannaisia
MY148644A (en) * 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
TWI638802B (zh) 2012-05-24 2018-10-21 芬蘭商奧利安公司 兒茶酚ｏ－甲基轉移酶活性抑制化合物
US20210347728A1 (en) 2018-07-25 2021-11-11 Orion Corporation 4,5-dihydroxy-2-(4-methylbenzyl)isophthalonitrile solvates and crystalline forms thereof
EP3877360A1 (en) 2018-11-09 2021-09-15 Orion Corporation Process for the preparation of 4,5-dihydroxy-2-(4-methylbenzyl)isophthalonitrile

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672042A (en) 1981-12-21 1987-06-09 Orion Research Puerto Rico, Inc. Method of and apparatus for chromatographic analysis
US5236952A (en) * 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
DK175069B1 (da) 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
US5283352A (en) * 1986-11-28 1994-02-01 Orion-Yhtyma Oy Pharmacologically active compounds, methods for the preparation thereof and compositions containing the same
FI864875A0 (fi) 1986-11-28 1986-11-28 Orion Yhtymae Oy Nya farmakologiskt aktiva foereningar, dessa innehaollande kompositioner samt foerfarande och mellanprodukter foer anvaendning vid framstaellning av dessa.
YU213587A (en) 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
US5489614A (en) 1987-11-27 1996-02-06 Orion-Yhtyma Oy Catechol derivatives, their physiologically acceptable salts, esters and use
MTP1031B (en) * 1987-12-24 1990-10-04 Orion Yhtymae Oy New use of cathecol-o-methyl transferase (comt) inhibitors and their physiologically acceptable salts and esters
US5185370A (en) 1988-09-01 1993-02-09 Orion-Yhtyma Oy Substituted β-diketones and their use
IL91382A (en) 1988-09-01 1995-06-29 Orion Yhtymae Oy Dicitons are converted into alkanyl or ethylmethylene, through their preparation and pharmaceutical preparations containing them
GB8903130D0 (en) 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
US5185332A (en) 1989-02-11 1993-02-09 Orion-Yhtyma Oy Thiadiazines and pharmaceutical compositions thereof as well as method of use
GB9510481D0 (en) 1995-05-24 1995-07-19 Orion Yhtymae Oy New catechol derivatives

Also Published As

Publication number Publication date
TR199901206T2 (xx) 1999-08-23
ZA9711468B (en) 1998-08-29
NO992985D0 (no) 1999-06-17
AU714086B2 (en) 1999-12-16
HUP0001097A3 (en) 2003-05-28
EE9700350A (et) 1998-10-15
PL334093A1 (en) 2000-01-31
CZ223199A3 (cs) 1999-11-17
HUP0001097A2 (hu) 2000-09-28
NZ336043A (en) 2000-12-22
SK79999A3 (en) 2000-05-16
NO992985L (no) 1999-06-17
YU28599A (sh) 2002-03-18
CZ291117B6 (cs) 2002-12-11
BG103491A (bg) 2000-04-28
US6207706B1 (en) 2001-03-27
IL130500A (en) 2003-02-12
IL130500A0 (en) 2000-06-01
EP0964678A1 (en) 1999-12-22
GB9626472D0 (en) 1997-02-05
ATE234613T1 (de) 2003-04-15
EP0964678B1 (en) 2003-03-19
JP2001507006A (ja) 2001-05-29
DE69720064D1 (de) 2003-04-24
AU7871198A (en) 1998-07-17
CA2275681A1 (en) 1998-07-02
KR20000057628A (ko) 2000-09-25
WO1998027973A1 (en) 1998-07-02
EA001673B1 (ru) 2001-06-25

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU