IL130460A0 - Method of preparation of physostigmine carbamate derivatives from eseroline ethers - Google Patents

Method of preparation of physostigmine carbamate derivatives from eseroline ethers

Info

Publication number
IL130460A0
IL130460A0 IL13046097A IL13046097A IL130460A0 IL 130460 A0 IL130460 A0 IL 130460A0 IL 13046097 A IL13046097 A IL 13046097A IL 13046097 A IL13046097 A IL 13046097A IL 130460 A0 IL130460 A0 IL 130460A0
Authority
IL
Israel
Prior art keywords
preparation
carbamate derivatives
eseroline
ethers
physostigmine carbamate
Prior art date
Application number
IL13046097A
Other languages
English (en)
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of IL130460A0 publication Critical patent/IL130460A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL13046097A 1996-12-19 1997-07-21 Method of preparation of physostigmine carbamate derivatives from eseroline ethers IL130460A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/769,409 US5677457A (en) 1996-12-19 1996-12-19 Method of preparation of physostigmine carbamate derivatives from eseroline ethers
PCT/US1997/012367 WO1998027096A1 (en) 1996-12-19 1997-07-21 Method of preparation of physostigmine carbamate derivatives from eseroline ethers

Publications (1)

Publication Number Publication Date
IL130460A0 true IL130460A0 (en) 2000-06-01

Family

ID=25085359

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13046097A IL130460A0 (en) 1996-12-19 1997-07-21 Method of preparation of physostigmine carbamate derivatives from eseroline ethers

Country Status (13)

Country Link
US (1) US5677457A (pt)
EP (1) EP0946560A1 (pt)
JP (1) JP2001506259A (pt)
KR (1) KR20000062263A (pt)
AR (1) AR009311A1 (pt)
AU (1) AU715483B2 (pt)
BR (1) BR9714046A (pt)
CA (1) CA2273180C (pt)
HU (1) HUP0000046A3 (pt)
IL (1) IL130460A0 (pt)
NO (1) NO993011L (pt)
WO (1) WO1998027096A1 (pt)
ZA (1) ZA976713B (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL135399A0 (en) * 1997-10-10 2001-05-20 Chiesi Farma Spa A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity
US6495700B1 (en) 2002-01-09 2002-12-17 Axonyx, Inc. Process for producing phenserine and its analog
CA2543322A1 (en) 2003-10-21 2005-05-12 Sention, Inc. Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents
MX2009008288A (es) * 2007-02-02 2009-12-01 Colucid Pharmaceuticals Inc Compuestos que inhiben la colinesterasa.
SE531698C2 (sv) 2007-07-12 2009-07-07 Respiratorius Ab Nya bronkdilaterande a,b-omättade amider
EP2182938A2 (en) * 2007-07-18 2010-05-12 Colucid Pharmaceuticals, Inc. Methods for promoting wakefulness
US8593728B2 (en) * 2009-02-19 2013-11-26 Toyota Motor Engineering & Manufacturing North America, Inc. Multilayer photonic structures

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2905054C3 (de) * 1979-02-08 1982-04-29 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 4-Hydroxyindolen
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US5187165A (en) * 1987-05-15 1993-02-16 Hoechst-Roussel Pharmaceuticals Inc. Memory enhancing and analgesic 1,2,3a,8,8a-hexahydro-3a,8(and 1,3a,8)-di(and tri)methylpyrrolo[2,3-b]indoles
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
DK0418770T3 (da) * 1989-09-19 1995-10-30 Hoechst Roussel Pharma Fremgangsmåde til kemisk spaltning af 5-alkoxysubstituerede (+-)-1,3-dimethyloxindolylethylaminer
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US4937341A (en) * 1989-09-28 1990-06-26 Hoechst-Roussel Pharmaceuticals Inc. Process for preparing N-aminocarbarbamates related to physostigmine
US5260452A (en) * 1989-11-03 1993-11-09 Hoechst-Roussel Pharmaceuticals Inc. 4- and 6-carbamates related to physostigmine and intermediates for the preparation thereof
US5177101A (en) * 1989-11-30 1993-01-05 Hoechst-Roussel Pharmaceuticals Incorporated Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine
US5077289A (en) * 1989-11-30 1991-12-31 Hoechst Roussel Pharmaceuticals Inc. Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine
US5274117A (en) * 1990-01-22 1993-12-28 Hoechst-Roussel Pharmaceuticals, Inc. Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
US5091541A (en) * 1990-02-01 1992-02-25 Hoechst-Roussel Pharmaceuticals Inc. Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
US4983616A (en) * 1990-02-01 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
US5216017A (en) * 1990-05-11 1993-06-01 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo[2,3-b]indole-ketones and analogs
US5173497A (en) * 1990-05-17 1992-12-22 Hoechst-Roussel Pharmaceuticals Incorporated Alpha-oxopyrrolo[2,3-B]indole acetic acids, esters, amides and related analogs
US5264587A (en) * 1990-05-17 1993-11-23 Hoechst-Roussel Pharmaceuticals Incorporated Method of preparing α-oxopyrrolo[2,3-b]indole acetic acids and derivatives
KR0172971B1 (ko) * 1990-06-27 1999-02-01 문캐로린디 1,2,3,3a,8,8a-헥사히드로-1,3a,8-트리메틸 피롤로[2,3-b]인돌의 테트라히드로 이소퀴놀리닐 카바메이트
US5231093A (en) * 1991-10-01 1993-07-27 Hoechst-Roussel Pharmaceuticals Incorporated Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
US5153193A (en) * 1991-10-01 1992-10-06 Hoechst-Roussel Pharmaceuticals Incorporated Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
US5234941A (en) * 1991-10-01 1993-08-10 Hoechst-Roussel Pharmaceuticals Incorporated Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
FI933264A (fi) * 1992-07-21 1994-01-22 Hoechst Roussel Pharma Foerfarande foer framstaellning av fysostigminkarbamatderivat fraon fysostigmin
US5302721A (en) * 1992-07-21 1994-04-12 Hoechst-Roussel Pharmaceuticals Incorporated Method of preparation of physostigmine carbamate derivatives from eseretholes
US5350762A (en) * 1993-03-08 1994-09-27 Hoechst-Roussel Pharmaceuticals Incorporated Tetrahydrocyclopent[B]indole methanamines and related compounds

Also Published As

Publication number Publication date
HUP0000046A2 (hu) 2000-06-28
US5677457A (en) 1997-10-14
ZA976713B (en) 1998-06-19
EP0946560A1 (en) 1999-10-06
KR20000062263A (ko) 2000-10-25
NO993011L (no) 1999-08-18
BR9714046A (pt) 2000-05-09
WO1998027096A1 (en) 1998-06-25
AU715483B2 (en) 2000-02-03
CA2273180C (en) 2002-10-29
JP2001506259A (ja) 2001-05-15
CA2273180A1 (en) 1998-06-25
HUP0000046A3 (en) 2000-09-28
AR009311A1 (es) 2000-04-12
NO993011D0 (no) 1999-06-18
AU3800897A (en) 1998-07-15

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