IL130335A - Serum-derived factor inducing cell differentiation and medical uses thereof - Google Patents

Serum-derived factor inducing cell differentiation and medical uses thereof

Info

Publication number
IL130335A
IL130335A IL13033597A IL13033597A IL130335A IL 130335 A IL130335 A IL 130335A IL 13033597 A IL13033597 A IL 13033597A IL 13033597 A IL13033597 A IL 13033597A IL 130335 A IL130335 A IL 130335A
Authority
IL
Israel
Prior art keywords
sdf
cells
fraction
complex
acetonitrile
Prior art date
Application number
IL13033597A
Other languages
English (en)
Other versions
IL130335A0 (en
Original Assignee
Hadasit Med Res Service
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hadasit Med Res Service filed Critical Hadasit Med Res Service
Publication of IL130335A0 publication Critical patent/IL130335A0/xx
Publication of IL130335A publication Critical patent/IL130335A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
IL13033597A 1996-12-10 1997-12-01 Serum-derived factor inducing cell differentiation and medical uses thereof IL130335A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3264696P 1996-12-10 1996-12-10
PCT/IL1997/000395 WO1998025634A1 (fr) 1996-12-10 1997-12-01 Facteur de serum induisant la differenciation cellulaire et utilisations medicales de ce dernier

Publications (2)

Publication Number Publication Date
IL130335A0 IL130335A0 (en) 2000-06-01
IL130335A true IL130335A (en) 2004-09-27

Family

ID=21866054

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13033597A IL130335A (en) 1996-12-10 1997-12-01 Serum-derived factor inducing cell differentiation and medical uses thereof

Country Status (7)

Country Link
US (2) US6372262B1 (fr)
EP (1) EP0973530A4 (fr)
JP (2) JP2001505906A (fr)
AU (1) AU731937B2 (fr)
CA (1) CA2274469C (fr)
IL (1) IL130335A (fr)
WO (1) WO1998025634A1 (fr)

Families Citing this family (11)

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JP2001505906A (ja) * 1996-12-10 2001-05-08 ハダジット メディカル リサーチ サービシズ アンド ディベラップメント カンパニー リミテッド 細胞の分化を誘導する血清由来因子およびその医薬的使用
US6962698B1 (en) 1998-02-17 2005-11-08 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
CA2344653A1 (fr) * 1998-09-29 2000-04-06 Gamida Cell Ltd. Procedes de regulation de la proliferation et de la differentiation de cellules souches et precurseurs
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
US20100125265A1 (en) * 2008-11-20 2010-05-20 Medtronic Vascular, Inc. Cell Delivery System to Induce Cell Growth and Angiogenesis
JP5872468B2 (ja) * 2009-07-24 2016-03-01 ロード アイランド ホスピタル アスパラギニル−β−ヒドロキシラーゼ発現腫瘍に対する樹状細胞ワクチン
US20150064273A1 (en) 2012-02-13 2015-03-05 Gamida-Cell Ltd. Mesenchymal Stem Cells Conditioned Medium and Methods of Generating and Using the Same
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
US11085023B2 (en) 2015-11-16 2021-08-10 Kenichi Yamahara Bovine serum composition and method for culturing cells using said bovine serum composition as additive
US11471497B1 (en) 2019-03-13 2022-10-18 David Gordon Bermudes Copper chelation therapeutics

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US4952607A (en) * 1982-05-27 1990-08-28 International Copper Research Association, Inc. Copper complex for treating cancer
IL68218A (en) * 1983-03-23 1985-12-31 Univ Ramot Compositions for cartilage repair comprising embryonal chondrocytes
JPS60149529A (ja) * 1984-01-14 1985-08-07 Mitsuyuki Shimizu 白血病細胞に対する分化誘導因子の産生方法
US4666844A (en) 1984-09-07 1987-05-19 Sungene Technologies Corporation Process for regenerating cereals
US5120831A (en) * 1985-02-08 1992-06-09 Procyte Corporation Metal-peptide compositions
US4935000A (en) * 1986-04-03 1990-06-19 East Carolina University Extracellular matrix induction method to produce pancreatic islet tissue
GB8615701D0 (en) * 1986-06-27 1986-08-06 Delta Biotechnology Ltd Stable gene integration vector
US5154931A (en) * 1986-10-22 1992-10-13 Gesellschaft Fur Biotechnologische Forschung Mbh (Gbf) Growth-stimulating material derived from porcine bone therefor and a manufacturing process
US5073492A (en) * 1987-01-09 1991-12-17 The Johns Hopkins University Synergistic composition for endothelial cell growth
US4863747A (en) * 1987-10-22 1989-09-05 Pioneer Hi-Bred International Bacterial treatment to preserve hay quality by addition of microorganisms of the genus Bacillus
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US5385933A (en) * 1989-02-27 1995-01-31 The United States Of America As Represented By The Department Of Health And Human Services Method for the treatment of cancer by use of the copper complex of S-(methylthio)-DL-homocysteine or the L-enantiomorph thereof
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
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US5635387A (en) * 1990-04-23 1997-06-03 Cellpro, Inc. Methods and device for culturing human hematopoietic cells and their precursors
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
US5071872A (en) * 1990-08-14 1991-12-10 The Ohio State University Research Foundation Method for improving interleukin-2 activity using aci-reductone compounds
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
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DE4240635C2 (de) * 1992-12-03 1997-07-10 Lothar Prof Dr Kanz Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren
CA2115522A1 (fr) * 1993-02-12 1994-08-13 Takeda Pharmaceutical Company Limited Muteine hst-2, adn codant pour cette muteine et preparation en contenant
US5654186A (en) * 1993-02-26 1997-08-05 The Picower Institute For Medical Research Blood-borne mesenchymal cells
JP3559585B2 (ja) * 1993-06-03 2004-09-02 株式会社林原生物化学研究所 トレハロース遊離酵素とその製造方法並びに用途
WO1995005843A1 (fr) * 1993-08-25 1995-03-02 Systemix, Inc. Procede de production d'une population de cellules souches hematopoietiques fortement enrichie
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US5565491A (en) * 1994-01-31 1996-10-15 Bristol-Myers Squibb Company Use of phosphotyrosine phospatase inhibitors for controlling cellular proliferation
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EP1105463A1 (fr) 1998-08-24 2001-06-13 t. Breeders, Inc. Population de cellules contenant des hemangioblastes d'origine non foetale et leur procede de production

Also Published As

Publication number Publication date
AU5133198A (en) 1998-07-03
EP0973530A4 (fr) 2002-01-16
IL130335A0 (en) 2000-06-01
JP2001505906A (ja) 2001-05-08
AU731937B2 (en) 2001-04-05
US6783775B2 (en) 2004-08-31
CA2274469C (fr) 2009-09-01
CA2274469A1 (fr) 1998-06-18
US6372262B1 (en) 2002-04-16
EP0973530A1 (fr) 2000-01-26
WO1998025634A1 (fr) 1998-06-18
US20020054916A1 (en) 2002-05-09
JP2004196816A (ja) 2004-07-15

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