IL130009A0 - Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth - Google Patents

Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth

Info

Publication number
IL130009A0
IL130009A0 IL13000997A IL13000997A IL130009A0 IL 130009 A0 IL130009 A0 IL 130009A0 IL 13000997 A IL13000997 A IL 13000997A IL 13000997 A IL13000997 A IL 13000997A IL 130009 A0 IL130009 A0 IL 130009A0
Authority
IL
Israel
Prior art keywords
growth
post
adenovirus vectors
modulate apoptosis
containing adenovirus
Prior art date
Application number
IL13000997A
Other languages
English (en)
Original Assignee
Univ Mcgill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Mcgill filed Critical Univ Mcgill
Publication of IL130009A0 publication Critical patent/IL130009A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
IL13000997A 1996-11-18 1997-11-18 Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth IL130009A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3105796P 1996-11-18 1996-11-18
PCT/IB1997/001619 WO1998022608A2 (en) 1996-11-18 1997-11-18 Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth

Publications (1)

Publication Number Publication Date
IL130009A0 true IL130009A0 (en) 2000-02-29

Family

ID=21857441

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13000997A IL130009A0 (en) 1996-11-18 1997-11-18 Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth

Country Status (7)

Country Link
US (1) US6060247A (https=)
EP (1) EP0943004A2 (https=)
JP (1) JP2001505766A (https=)
AU (1) AU742696B2 (https=)
CA (1) CA2272578A1 (https=)
IL (1) IL130009A0 (https=)
WO (1) WO1998022608A2 (https=)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6551618B2 (en) * 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US20020009747A1 (en) * 1997-08-25 2002-01-24 Freda Diane Miller Methods and reagents for identifying modulators of neuronal apoptosis
JP2002519648A (ja) * 1997-08-25 2002-07-02 マクギル ユニバーシティ ニューロンの生存に関与する化合物を検出するためのｓｈｐ−１およびｓｈｐ−２の使用
US6811992B1 (en) * 1998-05-14 2004-11-02 Ya Fang Liu Method for identifying MLK inhibitors for the treatment of neurological conditions
EP1173254A2 (en) * 1999-04-27 2002-01-23 Smithkline Beecham Plc Novel treatment of neurotraumatic conditions with a raf inhibitor
AU5599500A (en) * 1999-06-07 2000-12-28 J. David Gladstone Institutes, The Methods and compositions for preventing p53 mediated apoptosis
JP2003506711A (ja) * 1999-08-05 2003-02-18 セロミックス インコーポレイテッド 光学システムによる細胞の解析
EP1107003A1 (en) * 1999-12-09 2001-06-13 Trophos Methods for screening compounds active on neurons
AU2001282986A1 (en) 2000-07-26 2002-02-05 University Of Maryland, Baltimore The protein kinase domain of the large subunit of herpes simplex type 2 ribonucleotide reductase (icp10pk) has anti-apoptopic activity
US20040049024A1 (en) * 2001-12-07 2004-03-11 Geoff Clark Compositions and methods related to the minn1 tumor suppressor gene and protein
US20040001808A1 (en) * 2002-06-07 2004-01-01 Kenneth Haglid Compositions and methods for the use of Bcl-2 transfected neurons
DK1534819T3 (da) 2002-08-21 2010-04-19 Revivicor Inc Griselignende dyr, som mangler enhver ekspression af funktionel alfa-1,3-galactosyltransferase
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
EP1675597A2 (en) * 2003-10-21 2006-07-05 Aga Ab Use of xenon for the prevention of programmed cell death
US8603824B2 (en) 2004-07-26 2013-12-10 Pfenex, Inc. Process for improved protein expression by strain engineering
CA2909775A1 (en) 2005-08-09 2007-03-29 Revivicor, Inc. Transgenic ungulates expressing ctla4-ig and uses thereof
AU2008229648A1 (en) * 2007-03-20 2008-09-25 The Walter And Eliza Hall Institute Of Medical Research Method of screening
JP5444553B2 (ja) 2007-04-27 2014-03-19 フェネックス インコーポレイテッド 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および／または質が改善されている特定の株を同定する方法
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013091A1 (en) * 1991-01-18 1992-08-06 Oncogene Science, Inc. Methods of transcriptionally modulating expression of oncogenes and tumor suppressor genes
US5747469A (en) * 1991-03-06 1998-05-05 Board Of Regents, The University Of Texas System Methods and compositions comprising DNA damaging agents and p53
US6410010B1 (en) * 1992-10-13 2002-06-25 Board Of Regents, The University Of Texas System Recombinant P53 adenovirus compositions
ATE199568T1 (de) * 1993-02-16 2001-03-15 Onyx Pharma Inc Cytopatische viren zur therapie und prophylaxe der neoplasie
WO1995005738A1 (en) * 1993-08-20 1995-03-02 Massachusetts Institute Of Technology Anticancer agents and apoptosis
EP1637608B1 (en) * 1993-10-25 2009-07-22 CANJI, Inc. Recombinant adenoviral vector and methods of use
PT728214E (pt) * 1993-11-09 2004-11-30 Ohio Med College Linhas celulares estaveis capazes de expressar o gene de replicacao do virus adeno-associado
AU2283895A (en) * 1994-04-11 1995-10-30 Sloan-Kettering Institute For Cancer Research Defective herpes and defective adeno-associated virus vectors with p53 for the treatment of cancer
US5723333A (en) * 1995-02-10 1998-03-03 Regents Of The University Of California Human pancreatic cell lines: developments and uses

Also Published As

Publication number Publication date
WO1998022608A3 (en) 1998-09-03
US6060247A (en) 2000-05-09
AU742696B2 (en) 2002-01-10
WO1998022608A2 (en) 1998-05-28
AU5406498A (en) 1998-06-10
JP2001505766A (ja) 2001-05-08
CA2272578A1 (en) 1998-05-28
EP0943004A2 (en) 1999-09-22

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