CA2272578A1 - Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth - Google Patents
Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth Download PDFInfo
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- CA2272578A1 CA2272578A1 CA002272578A CA2272578A CA2272578A1 CA 2272578 A1 CA2272578 A1 CA 2272578A1 CA 002272578 A CA002272578 A CA 002272578A CA 2272578 A CA2272578 A CA 2272578A CA 2272578 A1 CA2272578 A1 CA 2272578A1
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Classifications
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
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- Chemical & Material Sciences (AREA)
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- Molecular Biology (AREA)
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- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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Applications Claiming Priority (3)
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| US3105796P | 1996-11-18 | 1996-11-18 | |
| US60/031,057 | 1996-11-18 | ||
| PCT/IB1997/001619 WO1998022608A2 (en) | 1996-11-18 | 1997-11-18 | Post-mitotic neurons containing adenovirus vectors that modulate apoptosis and growth |
Publications (1)
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| EP (1) | EP0943004A2 (https=) |
| JP (1) | JP2001505766A (https=) |
| AU (1) | AU742696B2 (https=) |
| CA (1) | CA2272578A1 (https=) |
| IL (1) | IL130009A0 (https=) |
| WO (1) | WO1998022608A2 (https=) |
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| US20020009747A1 (en) * | 1997-08-25 | 2002-01-24 | Freda Diane Miller | Methods and reagents for identifying modulators of neuronal apoptosis |
| JP2002519648A (ja) * | 1997-08-25 | 2002-07-02 | マクギル ユニバーシティ | ニューロンの生存に関与する化合物を検出するためのｓｈｐ−１およびｓｈｐ−２の使用 |
| US6811992B1 (en) * | 1998-05-14 | 2004-11-02 | Ya Fang Liu | Method for identifying MLK inhibitors for the treatment of neurological conditions |
| EP1173254A2 (en) * | 1999-04-27 | 2002-01-23 | Smithkline Beecham Plc | Novel treatment of neurotraumatic conditions with a raf inhibitor |
| AU5599500A (en) * | 1999-06-07 | 2000-12-28 | J. David Gladstone Institutes, The | Methods and compositions for preventing p53 mediated apoptosis |
| JP2003506711A (ja) * | 1999-08-05 | 2003-02-18 | セロミックス インコーポレイテッド | 光学システムによる細胞の解析 |
| EP1107003A1 (en) * | 1999-12-09 | 2001-06-13 | Trophos | Methods for screening compounds active on neurons |
| AU2001282986A1 (en) | 2000-07-26 | 2002-02-05 | University Of Maryland, Baltimore | The protein kinase domain of the large subunit of herpes simplex type 2 ribonucleotide reductase (icp10pk) has anti-apoptopic activity |
| US20040049024A1 (en) * | 2001-12-07 | 2004-03-11 | Geoff Clark | Compositions and methods related to the minn1 tumor suppressor gene and protein |
| US20040001808A1 (en) * | 2002-06-07 | 2004-01-01 | Kenneth Haglid | Compositions and methods for the use of Bcl-2 transfected neurons |
| DK1534819T3 (da) | 2002-08-21 | 2010-04-19 | Revivicor Inc | Griselignende dyr, som mangler enhver ekspression af funktionel alfa-1,3-galactosyltransferase |
| US9453251B2 (en) | 2002-10-08 | 2016-09-27 | Pfenex Inc. | Expression of mammalian proteins in Pseudomonas fluorescens |
| EP1675597A2 (en) * | 2003-10-21 | 2006-07-05 | Aga Ab | Use of xenon for the prevention of programmed cell death |
| US8603824B2 (en) | 2004-07-26 | 2013-12-10 | Pfenex, Inc. | Process for improved protein expression by strain engineering |
| CA2909775A1 (en) | 2005-08-09 | 2007-03-29 | Revivicor, Inc. | Transgenic ungulates expressing ctla4-ig and uses thereof |
| AU2008229648A1 (en) * | 2007-03-20 | 2008-09-25 | The Walter And Eliza Hall Institute Of Medical Research | Method of screening |
| JP5444553B2 (ja) | 2007-04-27 | 2014-03-19 | フェネックス インコーポレイテッド | 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および／または質が改善されている特定の株を同定する方法 |
| US9580719B2 (en) | 2007-04-27 | 2017-02-28 | Pfenex, Inc. | Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins |
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| WO1992013091A1 (en) * | 1991-01-18 | 1992-08-06 | Oncogene Science, Inc. | Methods of transcriptionally modulating expression of oncogenes and tumor suppressor genes |
| US5747469A (en) * | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
| US6410010B1 (en) * | 1992-10-13 | 2002-06-25 | Board Of Regents, The University Of Texas System | Recombinant P53 adenovirus compositions |
| ATE199568T1 (de) * | 1993-02-16 | 2001-03-15 | Onyx Pharma Inc | Cytopatische viren zur therapie und prophylaxe der neoplasie |
| WO1995005738A1 (en) * | 1993-08-20 | 1995-03-02 | Massachusetts Institute Of Technology | Anticancer agents and apoptosis |
| EP1637608B1 (en) * | 1993-10-25 | 2009-07-22 | CANJI, Inc. | Recombinant adenoviral vector and methods of use |
| PT728214E (pt) * | 1993-11-09 | 2004-11-30 | Ohio Med College | Linhas celulares estaveis capazes de expressar o gene de replicacao do virus adeno-associado |
| AU2283895A (en) * | 1994-04-11 | 1995-10-30 | Sloan-Kettering Institute For Cancer Research | Defective herpes and defective adeno-associated virus vectors with p53 for the treatment of cancer |
| US5723333A (en) * | 1995-02-10 | 1998-03-03 | Regents Of The University Of California | Human pancreatic cell lines: developments and uses |
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Also Published As
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| WO1998022608A3 (en) | 1998-09-03 |
| IL130009A0 (en) | 2000-02-29 |
| US6060247A (en) | 2000-05-09 |
| AU742696B2 (en) | 2002-01-10 |
| WO1998022608A2 (en) | 1998-05-28 |
| AU5406498A (en) | 1998-06-10 |
| JP2001505766A (ja) | 2001-05-08 |
| EP0943004A2 (en) | 1999-09-22 |
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| EEER | Examination request | ||
| FZDE | Discontinued |