IL128999A0 - Hedgehog interacting proteins and uses related thereto - Google Patents

Hedgehog interacting proteins and uses related thereto

Info

Publication number
IL128999A0
IL128999A0 IL12899997A IL12899997A IL128999A0 IL 128999 A0 IL128999 A0 IL 128999A0 IL 12899997 A IL12899997 A IL 12899997A IL 12899997 A IL12899997 A IL 12899997A IL 128999 A0 IL128999 A0 IL 128999A0
Authority
IL
Israel
Prior art keywords
hedgehog
interacting proteins
proteins
uses related
hedgehog interacting
Prior art date
Application number
IL12899997A
Other languages
English (en)
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of IL128999A0 publication Critical patent/IL128999A0/xx

Links

Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F13/00Interconnection of, or transfer of information or other signals between, memories, input/output devices or central processing units
    • G06F13/38Information transfer, e.g. on bus
    • G06F13/42Bus transfer protocol, e.g. handshake; Synchronisation
    • G06F13/4204Bus transfer protocol, e.g. handshake; Synchronisation on a parallel bus
    • G06F13/4234Bus transfer protocol, e.g. handshake; Synchronisation on a parallel bus being a memory bus
    • G06F13/4243Bus transfer protocol, e.g. handshake; Synchronisation on a parallel bus being a memory bus with synchronous protocol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Theoretical Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL12899997A 1996-09-20 1997-09-19 Hedgehog interacting proteins and uses related thereto IL128999A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2615596P 1996-09-20 1996-09-20
PCT/US1997/016741 WO1998012326A1 (fr) 1996-09-20 1997-09-19 Proteines d'interaction de type herisson et utilisations s'y rapportant

Publications (1)

Publication Number Publication Date
IL128999A0 true IL128999A0 (en) 2000-02-17

Family

ID=21830211

Family Applications (3)

Application Number Title Priority Date Filing Date
IL12899997A IL128999A0 (en) 1996-09-20 1997-09-19 Hedgehog interacting proteins and uses related thereto
IL128999A IL128999A (en) 1996-09-20 1999-03-15 Proteins that interact with the HEDGEHOG gene and its uses
IL181578A IL181578A (en) 1996-09-20 2007-02-26 Antibodies which are specifically immunoreactive with hedgehog interacting proteins and a hybridoma producing such antibodies

Family Applications After (2)

Application Number Title Priority Date Filing Date
IL128999A IL128999A (en) 1996-09-20 1999-03-15 Proteins that interact with the HEDGEHOG gene and its uses
IL181578A IL181578A (en) 1996-09-20 2007-02-26 Antibodies which are specifically immunoreactive with hedgehog interacting proteins and a hybridoma producing such antibodies

Country Status (11)

Country Link
US (3) US6514724B1 (fr)
EP (1) EP0935656B1 (fr)
JP (1) JP4083810B2 (fr)
AT (1) ATE335819T1 (fr)
AU (1) AU742972B2 (fr)
CA (1) CA2266429C (fr)
DE (1) DE69736484T2 (fr)
DK (1) DK0935656T3 (fr)
ES (1) ES2278396T3 (fr)
IL (3) IL128999A0 (fr)
WO (1) WO1998012326A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8173098A (en) 1997-06-27 1999-01-19 Ontogeny, Inc. Neuroprotective methods and reagents
US7144997B2 (en) 1997-07-24 2006-12-05 Curis, Inc. Vertebrate embryonic patterning-inducing proteins, compositions and uses related therto
US6639051B2 (en) 1997-10-20 2003-10-28 Curis, Inc. Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
US6309879B1 (en) 1997-12-08 2001-10-30 Curis, Inc. Human patched genes and proteins, and uses related thereto
US7339033B2 (en) * 1998-06-26 2008-03-04 Genentech, Inc. Pro1481
AU765485B2 (en) 1998-11-02 2003-09-18 Curis, Inc. Functional antagonists of hedgehog activity
US6884770B1 (en) 1998-11-06 2005-04-26 Curis, Inc. Methods and compositions for treating or preventing peripheral neuropathies
GB0013674D0 (en) * 1999-06-08 2000-07-26 Lorantis Ltd Therapeutic use
US7517870B2 (en) * 2004-12-03 2009-04-14 Fondazione Telethon Use of compounds that interfere with the hedgehog signaling pathway for the manufacture of a medicament for preventing, inhibiting, and/or reversing ocular diseases related with ocular neovascularization
CA2650338C (fr) * 2006-04-27 2013-04-16 Illinois Tool Works Inc. Systeme de refrigeration de plat avec refrigerant a etat unique
NZ589806A (en) * 2008-05-30 2012-08-31 Curis Inc Variant hedgehog-interacting protein (hhip1) and methods and uses thereof
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
WO2017049125A1 (fr) * 2015-09-16 2017-03-23 La Jolla Nanomedical Système de nanoparticules ciblé vers une activité cellulaire et procédés de production du système de nanoparticules
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria
WO2023211805A1 (fr) * 2022-04-26 2023-11-02 The Regents Of The University Of California Protéines de fusion hhip-fc et leurs utilisations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5200313A (en) * 1983-08-05 1993-04-06 Miles Inc. Nucleic acid hybridization assay employing detectable anti-hybrid antibodies
US5789543A (en) * 1993-12-30 1998-08-04 President And Fellows Of Harvard College Vertebrate embryonic pattern-inducing proteins and uses related thereto
EP0741783B1 (fr) * 1993-12-30 2009-03-18 President And Fellows Of Harvard College Proteines de type "hedgehog" induisant une structure embryonnaire chez les vertebres
ES2245454T3 (es) * 1994-10-07 2006-01-01 The Board Of Trustees Of The Leland Stanford Junior University Genes patched y su utilizacion.
US6281332B1 (en) * 1994-12-02 2001-08-28 The Johns Hopkins University School Of Medicine Hedgehog-derived polypeptides

Also Published As

Publication number Publication date
CA2266429A1 (fr) 1998-03-26
AU742972B2 (en) 2002-01-17
IL181578A (en) 2010-12-30
US7115394B2 (en) 2006-10-03
CA2266429C (fr) 2010-05-18
JP2001501468A (ja) 2001-02-06
IL128999A (en) 2008-03-20
DE69736484T2 (de) 2007-03-29
ES2278396T3 (es) 2007-08-01
AU4489297A (en) 1998-04-14
EP0935656B1 (fr) 2006-08-09
EP0935656A1 (fr) 1999-08-18
US7585671B2 (en) 2009-09-08
JP4083810B2 (ja) 2008-04-30
IL181578A0 (en) 2007-07-04
ATE335819T1 (de) 2006-09-15
US20070054290A1 (en) 2007-03-08
DK0935656T3 (da) 2006-12-11
US20030143595A1 (en) 2003-07-31
DE69736484D1 (de) 2006-09-21
WO1998012326A1 (fr) 1998-03-26
US6514724B1 (en) 2003-02-04

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