WO2003025006A3 - Nouveaux polypeptides purifies impliques dans le metabolisme des cofacteurs - Google Patents

Nouveaux polypeptides purifies impliques dans le metabolisme des cofacteurs Download PDF

Info

Publication number
WO2003025006A3
WO2003025006A3 PCT/CA2002/001427 CA0201427W WO03025006A3 WO 2003025006 A3 WO2003025006 A3 WO 2003025006A3 CA 0201427 W CA0201427 W CA 0201427W WO 03025006 A3 WO03025006 A3 WO 03025006A3
Authority
WO
WIPO (PCT)
Prior art keywords
purified polypeptides
polypeptides involved
metabolism
factor
factor metabolism
Prior art date
Application number
PCT/CA2002/001427
Other languages
English (en)
Other versions
WO2003025006A2 (fr
Inventor
Aled Edwards
Akil Dharamsi
Masoud Vedadi
Muhammad Zahoor Alam
Donald Awrey
Bryan Beattie
Veronica Canadien
Megan Domagala
Simon Houston
Dhushy Kanagarajah
Qin Li
Sasha Necakov
Kathleen Nethery
Benjamin Pinder
Bay Sheldrick
Francois Vallee
Cristina Viola
Original Assignee
Affinium Pharm Inc
Aled Edwards
Akil Dharamsi
Masoud Vedadi
Muhammad Zahoor Alam
Donald Awrey
Bryan Beattie
Veronica Canadien
Megan Domagala
Simon Houston
Dhushy Kanagarajah
Qin Li
Sasha Necakov
Kathleen Nethery
Benjamin Pinder
Bay Sheldrick
Francois Vallee
Cristina Viola
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affinium Pharm Inc, Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Zahoor Alam, Donald Awrey, Bryan Beattie, Veronica Canadien, Megan Domagala, Simon Houston, Dhushy Kanagarajah, Qin Li, Sasha Necakov, Kathleen Nethery, Benjamin Pinder, Bay Sheldrick, Francois Vallee, Cristina Viola filed Critical Affinium Pharm Inc
Priority to AU2002328223A priority Critical patent/AU2002328223A1/en
Publication of WO2003025006A2 publication Critical patent/WO2003025006A2/fr
Publication of WO2003025006A3 publication Critical patent/WO2003025006A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/86—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides, e.g. penicillinase (3.5.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/04—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with a disulfide as acceptor (1.2.4)
    • C12Y102/04001—Pyruvate dehydrogenase (acetyl-transferring) (1.2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
    • C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
    • C12Y305/04025—GTP cyclohydrolase II (3.5.4.25)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des cibles polypeptides pour des bactéries pathogènes. L'invention concerne également les caractéristiques biochimiques et biophysiques de ces polypeptides.
PCT/CA2002/001427 2001-09-21 2002-09-20 Nouveaux polypeptides purifies impliques dans le metabolisme des cofacteurs WO2003025006A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002328223A AU2002328223A1 (en) 2001-09-21 2002-09-20 Purified polypeptides involved in co-factor metabolism

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US32411501P 2001-09-21 2001-09-21
US60/324,115 2001-09-21
US32533701P 2001-09-27 2001-09-27
US60/325,337 2001-09-27
US32637801P 2001-10-01 2001-10-01
US32632101P 2001-10-01 2001-10-01
US60/326,378 2001-10-01
US60/326,321 2001-10-01
US32682001P 2001-10-03 2001-10-03
US60/326,820 2001-10-03
US33570201P 2001-10-25 2001-10-25
US60/335,702 2001-10-25
US34053601P 2001-10-26 2001-10-26
US60/340,536 2001-10-26
US35090701P 2001-10-29 2001-10-29
US60/350,907 2001-10-29

Publications (2)

Publication Number Publication Date
WO2003025006A2 WO2003025006A2 (fr) 2003-03-27
WO2003025006A3 true WO2003025006A3 (fr) 2004-02-19

Family

ID=27575388

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2002/001427 WO2003025006A2 (fr) 2001-09-21 2002-09-20 Nouveaux polypeptides purifies impliques dans le metabolisme des cofacteurs

Country Status (2)

Country Link
AU (1) AU2002328223A1 (fr)
WO (1) WO2003025006A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5634659B2 (ja) 2004-12-22 2014-12-03 ミシガン バイオテクノロジー インスティテュート 有機酸を高産生するための組換え微生物米国政府の援助に関する記載本発明は、エネルギー省によって授与された協力契約番号（ＣｏｏｐｅｒａｔｉｖｅＡｇｒｅｅｍｅｎｔＮｏ．）ＤＥ−ＦＣ３６−０２ＧＯ１２００１において米国政府から援助を受けてなされた。米国政府は、本発明において一定の権利を有する。
EP2497778A3 (fr) * 2006-05-31 2012-12-12 Metanomics GmbH Manipulation du métabolisme d'azote

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 14 February 1992 (1992-02-14), XP002253216, Database accession no. X64395 *
DATABASE EMBL [online] 29 January 1997 (1997-01-29), XP002253215, Database accession no. AE000148 *
DATABASE SWISSPROT [online] 1 March 2002 (2002-03-01), XP002253218, Database accession no. Q8XE88 *
DATABASE SWISSPROT [online] 1 May 1992 (1992-05-01), XP002253217, Database accession no. P25539 *

Also Published As

Publication number Publication date
WO2003025006A2 (fr) 2003-03-27
AU2002328223A1 (en) 2003-04-01

Similar Documents

Publication Publication Date Title
WO1999058571A3 (fr) Proteine hybride pour l'inhibition de la degranulation des mastocytes et son utilisation
WO2004041854A3 (fr) Nouveaux polypeptides bacteriens essentiels
WO2003087353A3 (fr) Nouveaux polypeptides purifies impliques dans la biogenese membranaire
WO2006028561A3 (fr) Nouveaux polypeptides fabi purifies issus de fransicella tularensis
WO2001079446A3 (fr) Matieres et procedes relatifs au metabolisme lipidique
AU2002349231A1 (en) Methylotrophic bacterium for the production of recombinant proteins and other products
WO2003044185A3 (fr) Nouveaux polypeptides purifies iimpliques dans un metabolisme general
WO2003025006A3 (fr) Nouveaux polypeptides purifies impliques dans le metabolisme des cofacteurs
WO2003084986A3 (fr) Nouveaux polypeptides modifies impliques dans le metabolisme cellulaire
WO2003102190A3 (fr) Nouveaux polypeptides purifies responsables de la viabilite bacterienne
WO2004044189A3 (fr) Nouveaux polypeptides purifies jouant un role dans le metabolisme
WO2003027139A3 (fr) Nouveaux polypeptides purifiees impliques dans la biosynthese membranaire
WO2003025004A3 (fr) Polypeptides purifies intervenant dans le traitement d'acides nucleiques
WO2003025008A3 (fr) Nouveaux polypeptides purifies impliques dans le traitement de proteines
WO2003083099A3 (fr) Nouveaux polypeptides purifies impliques dans la synthese et la modification des proteines
WO2003045986A3 (fr) Nouveaux polypeptides purifies impliques dans le metabolisme general
WO2003025007A3 (fr) Nouveaux polypeptides purifies impliques dans la biosynthese membranaire
WO2003045985A3 (fr) Nouveaux polypeptides purifies impliques dans le metabolisme coenzymatique et glucidique
WO2003087145A3 (fr) Nouveaux polypeptides purifies impliques dans la detection de densite cellulaire
WO2003025005A3 (fr) Nouveaux polypeptides purifies impliques dans le traitement des proteines
WO2003087354A3 (fr) Nouveaux polypeptides purifies impliques dans le transport et le metabolisme nucleotidiques
AU2002362414A1 (en) Novel molecules of the hkid-1-related protein family and uses thereof
WO2003035858A3 (fr) Nouveaux polypeptides purifies impliques dans le traitement des acides nucleiques
WO2004058809A3 (fr) Nouveaux polypeptides bacteriens essentiels
WO2003085103A3 (fr) Nouveaux polypeptides purifies impliques dans l'hydrolyse de nucleotides

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG US UZ VC VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP