WO2003035858A3 - Nouveaux polypeptides purifies impliques dans le traitement des acides nucleiques - Google Patents

Nouveaux polypeptides purifies impliques dans le traitement des acides nucleiques Download PDF

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Publication number
WO2003035858A3
WO2003035858A3 PCT/CA2002/001613 CA0201613W WO03035858A3 WO 2003035858 A3 WO2003035858 A3 WO 2003035858A3 CA 0201613 W CA0201613 W CA 0201613W WO 03035858 A3 WO03035858 A3 WO 03035858A3
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WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid processing
polypeptides involved
bacterial polypeptides
bacterial
Prior art date
Application number
PCT/CA2002/001613
Other languages
English (en)
Other versions
WO2003035858A2 (fr
Inventor
Aled Edwards
Akil Dharamsi
Masoud Vedadi
Muhammad Zahoor Alam
Donald Awrey
Bryan Beattie
Veronica Canadien
Megan Domagala
Simon Houston
Qin Li
Kamran Mansoury
Sasha Necakov
Ivy Ng
Benjamin Pinder
Bay Sheldrick
Olga Wrezel
Original Assignee
Affinium Pharm Inc
Aled Edwards
Akil Dharamsi
Masoud Vedadi
Muhammad Zahoor Alam
Donald Awrey
Bryan Beattie
Veronica Canadien
Megan Domagala
Simon Houston
Qin Li
Kamran Mansoury
Sasha Necakov
Ivy Ng
Benjamin Pinder
Bay Sheldrick
Olga Wrezel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affinium Pharm Inc, Aled Edwards, Akil Dharamsi, Masoud Vedadi, Muhammad Zahoor Alam, Donald Awrey, Bryan Beattie, Veronica Canadien, Megan Domagala, Simon Houston, Qin Li, Kamran Mansoury, Sasha Necakov, Ivy Ng, Benjamin Pinder, Bay Sheldrick, Olga Wrezel filed Critical Affinium Pharm Inc
Priority to AU2002333143A priority Critical patent/AU2002333143A1/en
Publication of WO2003035858A2 publication Critical patent/WO2003035858A2/fr
Priority to US10/806,062 priority patent/US20050214773A1/en
Priority to US10/922,802 priority patent/US20050187718A1/en
Publication of WO2003035858A3 publication Critical patent/WO2003035858A3/fr

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1229—Phosphotransferases with a phosphate group as acceptor (2.7.4)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56944—Streptococcus

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des cibles de polypeptides pour bactéries pathogènes. L'invention concerne également les caractéristiques biochimiques et biophysiques de ces polypeptides.
PCT/CA2002/001613 2001-09-21 2002-10-25 Nouveaux polypeptides purifies impliques dans le traitement des acides nucleiques WO2003035858A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002333143A AU2002333143A1 (en) 2001-10-25 2002-10-25 Bacterial polypeptides involved in nucleic acid processing
US10/806,062 US20050214773A1 (en) 2001-09-21 2004-03-22 Novel purified polypeptides from bacteria
US10/922,802 US20050187718A1 (en) 2001-09-21 2004-08-20 Novel purified polypeptides from Streptococcus pneumoniae

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US33762501P 2001-10-25 2001-10-25
US60/337,625 2001-10-25
US34053401P 2001-10-26 2001-10-26
US60/340,534 2001-10-26
US34182501P 2001-12-18 2001-12-18
US34163901P 2001-12-18 2001-12-18
US60/341,639 2001-12-18
US60/341,825 2001-12-18
US34200401P 2001-12-19 2001-12-19
US60/342,004 2001-12-19
US34255901P 2001-12-20 2001-12-20
US60/342,559 2001-12-20

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10/806,062 Continuation-In-Part US20050214773A1 (en) 2001-09-21 2004-03-22 Novel purified polypeptides from bacteria
US10/922,802 Continuation-In-Part US20050187718A1 (en) 2001-09-21 2004-08-20 Novel purified polypeptides from Streptococcus pneumoniae

Publications (2)

Publication Number Publication Date
WO2003035858A2 WO2003035858A2 (fr) 2003-05-01
WO2003035858A3 true WO2003035858A3 (fr) 2005-08-11

Family

ID=27559773

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2002/001613 WO2003035858A2 (fr) 2001-09-21 2002-10-25 Nouveaux polypeptides purifies impliques dans le traitement des acides nucleiques

Country Status (2)

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AU (1) AU2002333143A1 (fr)
WO (1) WO2003035858A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0311789D0 (en) * 2003-05-22 2003-06-25 Astrazeneca Ab Method
US20080095743A1 (en) * 2004-04-23 2008-04-24 The Government Of The United States Of America As Monoclonal Antibody that Specifically Binds Stem Cells and its Use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0900847A2 (fr) * 1997-08-05 1999-03-10 Smithkline Beecham Corporation Phosphoribosyltransférase de Staphylococcus aureus
US6162627A (en) * 1998-03-19 2000-12-19 University Of Medicine And Dentistry Of New Jersey Methods of identifying inhibitors of sensor histidine kinases through rational drug design

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0900847A2 (fr) * 1997-08-05 1999-03-10 Smithkline Beecham Corporation Phosphoribosyltransférase de Staphylococcus aureus
US6162627A (en) * 1998-03-19 2000-12-19 University Of Medicine And Dentistry Of New Jersey Methods of identifying inhibitors of sensor histidine kinases through rational drug design

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE SWALL EBI; FUJIMURA ET AL.: "Adenine phosphoribosyltransferase (E.C. 2.4.2.7)" *
DRY SARAH ET AL: "Structural genomics in the biotechnology sector.", NATURE STRUCTURAL BIOLOGY, vol. 7, no. Supplement, November 2000 (2000-11-01), pages 946 - 949, XP002963281, ISSN: 1072-8368 *
FUJIMURA T ET AL: "Increase of Methicillin resistance in Staphylococcus aureus caused by deletion of a gene whose product is homologous to lytic enzymes", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 179, no. 20, O32418, October 1997 (1997-10-01), pages 6294 - 6301, XP002122730, ISSN: 0021-9193 *
LOFERER HANNES ET AL: "Integrated bacterial genomics for the discovery of novel antimicrobials.", DRUG DISCOVERY TODAY, vol. 5, no. 3, March 2000 (2000-03-01), pages 107 - 114, XP002250074, ISSN: 1359-6446 *

Also Published As

Publication number Publication date
WO2003035858A2 (fr) 2003-05-01
AU2002333143A1 (en) 2003-05-06
AU2002333143A8 (en) 2005-11-17

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