IL127238A - Cellular internalization of PIGR cane and associated ligands - Google Patents

Cellular internalization of PIGR cane and associated ligands

Info

Publication number
IL127238A
IL127238A IL12723897A IL12723897A IL127238A IL 127238 A IL127238 A IL 127238A IL 12723897 A IL12723897 A IL 12723897A IL 12723897 A IL12723897 A IL 12723897A IL 127238 A IL127238 A IL 127238A
Authority
IL
Israel
Prior art keywords
ser
ala
gly
asp
ligand
Prior art date
Application number
IL12723897A
Other languages
English (en)
Hebrew (he)
Other versions
IL127238A0 (en
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of IL127238A0 publication Critical patent/IL127238A0/xx
Publication of IL127238A publication Critical patent/IL127238A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4712Cystic fibrosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/02Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from eggs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • A61K2039/6056Antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/022Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Holo Graphy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL12723897A 1996-06-04 1997-05-14 Cellular internalization of PIGR cane and associated ligands IL127238A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1895896P 1996-06-04 1996-06-04
PCT/US1997/007944 WO1997046588A1 (en) 1996-06-04 1997-05-14 Cellular internalization of pigr stalk and associated ligands

Publications (2)

Publication Number Publication Date
IL127238A0 IL127238A0 (en) 1999-09-22
IL127238A true IL127238A (en) 2001-07-24

Family

ID=21790632

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12723897A IL127238A (en) 1996-06-04 1997-05-14 Cellular internalization of PIGR cane and associated ligands

Country Status (11)

Country Link
US (2) US6042833A (de)
EP (1) EP0934338B1 (de)
JP (1) JP2000511432A (de)
CN (1) CN1221428A (de)
AT (1) ATE338065T1 (de)
AU (1) AU728587B2 (de)
CA (1) CA2256304A1 (de)
DE (1) DE69736602D1 (de)
IL (1) IL127238A (de)
RU (1) RU2191781C2 (de)
WO (1) WO1997046588A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU749032B2 (en) * 1997-06-13 2002-06-20 Johns Hopkins University, The Therapeutic nanospheres
AU769259B2 (en) * 1999-02-12 2004-01-22 Board Of Regents, The University Of Texas System Polymeric immunoglobulin receptor (pIgR)-binding domains and methods of use therefor
WO2001049710A2 (de) * 1999-12-30 2001-07-12 Frank Hans Georg Verfahren zur identifizierung von substanzen, die säugetier-epitope nachahmen
MXPA02009449A (es) * 2000-03-27 2003-09-22 Univ California Ligandos dirigidos a la region no del eje del componente no secretor de la pigr y metodos de uso de los mismos.
US20020136732A1 (en) * 2000-04-23 2002-09-26 Houston L. L. Compositions comprising carriers and transportable complexes
US6924412B1 (en) * 2000-07-21 2005-08-02 Arriwan Holding B.V. Means and methods for raising antibody concentration in compartments of the body of a non-human animal
JP2005500002A (ja) * 2000-10-02 2005-01-06 エリゼク・ファーマシュウティカルズ・インコーポレイテッド 生物学的に活性な薬剤を細胞関門を越えて輸送するための組成物および方法
US20030166160A1 (en) * 2001-09-06 2003-09-04 Hawley Stephen B. Compounds and molecular complexes comprising multiple binding regions directed to transcytotic ligands
US20040219542A1 (en) * 2001-02-02 2004-11-04 L.L. Houston Compositions and methods for identifying, characterizing, optimizing and using ligands to transcytotic molecules
EP1587524A4 (de) * 2003-01-09 2006-07-26 Arizeke Pharmaceuticals Inc Zusammensetzungen und verfahren für die gezielte biologische abgabe von molekularen trägern
RU2382052C1 (ru) * 2008-07-09 2010-02-20 Институт синтетических полимерных материалов (ИСПМ) им. Н.С. Ениколопова РАН Способ получения модифицированной токоферолом сшитой соли гиалуроновой кислоты и биоактивная композиция на ее основе
MX2022001278A (es) * 2019-08-02 2022-05-03 Janssen Biotech Inc Materiales y métodos para el direccionamiento al receptor de anticuerpos poliméricos.
CN116322776A (zh) 2020-08-03 2023-06-23 詹森生物科技公司 用于病毒治疗剂中的多向生物转运的材料和方法
CN114088939A (zh) * 2021-11-19 2022-02-25 中国人民解放军陆军军医大学第一附属医院 一种原发性胆汁性胆管炎诊断用分子标志物及其应用
CN116444612B (zh) * 2022-11-30 2024-07-16 内蒙古伊利实业集团股份有限公司 乳源活性肽apadpgrptgy及其制备方法与应用

Also Published As

Publication number Publication date
EP0934338A4 (de) 2002-05-29
ATE338065T1 (de) 2006-09-15
CN1221428A (zh) 1999-06-30
DE69736602D1 (de) 2006-10-12
RU2191781C2 (ru) 2002-10-27
AU3063297A (en) 1998-01-05
WO1997046588A1 (en) 1997-12-11
AU728587B2 (en) 2001-01-11
JP2000511432A (ja) 2000-09-05
CA2256304A1 (en) 1997-12-11
US6340743B1 (en) 2002-01-22
US6042833A (en) 2000-03-28
IL127238A0 (en) 1999-09-22
EP0934338A1 (de) 1999-08-11
EP0934338B1 (de) 2006-08-30

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