IL127143A0 - Phospholipid terivatives of non-steroidal anti inflammatory drugs - Google Patents

Phospholipid terivatives of non-steroidal anti inflammatory drugs

Info

Publication number
IL127143A0
IL127143A0 IL12714398A IL12714398A IL127143A0 IL 127143 A0 IL127143 A0 IL 127143A0 IL 12714398 A IL12714398 A IL 12714398A IL 12714398 A IL12714398 A IL 12714398A IL 127143 A0 IL127143 A0 IL 127143A0
Authority
IL
Israel
Prior art keywords
steroidal anti
phospholipid
inflammatory drugs
terivatives
anti inflammatory
Prior art date
Application number
IL12714398A
Other languages
English (en)
Original Assignee
Dpharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dpharm Ltd filed Critical Dpharm Ltd
Priority to IL12714398A priority Critical patent/IL127143A0/xx
Publication of IL127143A0 publication Critical patent/IL127143A0/xx
Priority to AU12928/00A priority patent/AU766045B2/en
Priority to CA2346869A priority patent/CA2346869C/en
Priority to EP99956297A priority patent/EP1131326B1/en
Priority to NZ510938A priority patent/NZ510938A/xx
Priority to PCT/IL1999/000623 priority patent/WO2000031083A1/en
Priority to AT99956297T priority patent/ATE239739T1/de
Priority to DE69907720T priority patent/DE69907720T2/de
Priority to US09/856,009 priority patent/US6730696B1/en
Priority to IL14268399A priority patent/IL142683A/en
Priority to JP2000583911A priority patent/JP2002530410A/ja
Priority to ZA200102718A priority patent/ZA200102718B/en
Priority to US10/757,098 priority patent/US7173018B2/en
Priority to US11/643,189 priority patent/US7417035B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IL12714398A 1998-11-19 1998-11-19 Phospholipid terivatives of non-steroidal anti inflammatory drugs IL127143A0 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IL12714398A IL127143A0 (en) 1998-11-19 1998-11-19 Phospholipid terivatives of non-steroidal anti inflammatory drugs
JP2000583911A JP2002530410A (ja) 1998-11-19 1999-11-18 非ステロイド抗炎症薬のリン脂質誘導体
AT99956297T ATE239739T1 (de) 1998-11-19 1999-11-18 Phospholipid-derivate von nichtsteroiden entzündungshemmenden medikamenten
CA2346869A CA2346869C (en) 1998-11-19 1999-11-18 Phospholipid derivatives of non-steroidal anti-inflammatory drugs
EP99956297A EP1131326B1 (en) 1998-11-19 1999-11-18 Phospholipid derivatives of non-steroidal anti-inflammatory drugs
NZ510938A NZ510938A (en) 1998-11-19 1999-11-18 Phospholipid derivatives of non-steroidal anti-inflammatory drugs
PCT/IL1999/000623 WO2000031083A1 (en) 1998-11-19 1999-11-18 Phospholipid derivatives of non-steroidal anti-inflammatory drugs
AU12928/00A AU766045B2 (en) 1998-11-19 1999-11-18 Phospholipid derivatives of non-steroidal anti-inflammatory drugs
DE69907720T DE69907720T2 (de) 1998-11-19 1999-11-18 Phospholipid-derivate von nichtsteroiden entzündungshemmenden medikamenten
US09/856,009 US6730696B1 (en) 1998-11-19 1999-11-18 Phospholipid derivatives of non-steroidal anti-inflammatory drugs
IL14268399A IL142683A (en) 1998-11-19 1999-11-18 Phospholipid derivatives of non-steroidal anti-inflammatory drugs
ZA200102718A ZA200102718B (en) 1998-11-19 2001-04-03 Phospholipid derivatives of non-steroidal anti-inflammatory drugs.
US10/757,098 US7173018B2 (en) 1998-11-19 2004-01-14 Phospholipid derivatives of non-steroidal anti-inflammatory drugs
US11/643,189 US7417035B2 (en) 1998-11-19 2006-12-20 Phospholipid derivatives of non-steroidal anti-inflammatory drugs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL12714398A IL127143A0 (en) 1998-11-19 1998-11-19 Phospholipid terivatives of non-steroidal anti inflammatory drugs

Publications (1)

Publication Number Publication Date
IL127143A0 true IL127143A0 (en) 1999-09-22

Family

ID=11072158

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12714398A IL127143A0 (en) 1998-11-19 1998-11-19 Phospholipid terivatives of non-steroidal anti inflammatory drugs

Country Status (11)

Country Link
US (3) US6730696B1 (xx)
EP (1) EP1131326B1 (xx)
JP (1) JP2002530410A (xx)
AT (1) ATE239739T1 (xx)
AU (1) AU766045B2 (xx)
CA (1) CA2346869C (xx)
DE (1) DE69907720T2 (xx)
IL (1) IL127143A0 (xx)
NZ (1) NZ510938A (xx)
WO (1) WO2000031083A1 (xx)
ZA (1) ZA200102718B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL127143A0 (en) 1998-11-19 1999-09-22 Dpharm Ltd Phospholipid terivatives of non-steroidal anti inflammatory drugs
AU2003211052A1 (en) * 2002-02-11 2003-09-04 Vertex Pharmaceuticals Incorporated Phospholipids as caspase inhibitor prodrugs
US20070053984A1 (en) * 2005-03-03 2007-03-08 Monique Spann-Wade Topical gels compositions
DE102006019907A1 (de) * 2006-04-28 2007-10-31 Müller-Enoch, Dieter, Prof. Dr. Verwendung von substituierten Glycerinderivaten zur Herstellung einer pharmazeutischen Zubereitung
US20080317684A1 (en) * 2006-09-06 2008-12-25 Isw Group, Inc. Topical Compositions
BRPI0818265A2 (pt) * 2007-10-30 2017-05-09 Athera Biotechnologies Ab usos de pelo menos um derivado de fator ativador de plaquetas (paf) ou um conjugado de fator ativador de plaquetas (paf), e de pelo menos uma preparação de anticorpo, e, métodos para imunização e profilaxia, prevenção e tratamento de um mamífero e de diagnose da presença ou ausência de anticorpos igm, igg ou iga relacionados com o risco aumentado ou decrescido de desenvolvimento de doenças cardiovasculares isquêmicas.
EP2646056A1 (en) 2010-12-02 2013-10-09 Ben Gurion University of the Negev Research and Development Authority Conjugates of a phospholipid and a drug for the treatment of inflammatory bowel disease
US20230285292A1 (en) * 2020-06-23 2023-09-14 The Trustees Of The University Of Pennsylvania Compositions and methods of using a pla2-responsive drug delivery system

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223263A (en) 1988-07-07 1993-06-29 Vical, Inc. Liponucleotide-containing liposomes
US5352673A (en) * 1989-08-29 1994-10-04 Dennis Edward A Prodrugs
WO1991016920A1 (en) * 1990-05-07 1991-11-14 Vical, Inc. Lipid prodrugs of salicylate and nonsteroidal anti-inflammatory drugs
US5563257A (en) * 1990-08-20 1996-10-08 Boehringer Mannheim Gmbh Phospholipid derivatives of nucleosides
US5543389A (en) 1990-11-01 1996-08-06 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University, A Non Profit Organization Covalent polar lipid-peptide conjugates for use in salves
US5149794A (en) 1990-11-01 1992-09-22 State Of Oregon Covalent lipid-drug conjugates for drug targeting
US5256641A (en) 1990-11-01 1993-10-26 State Of Oregon Covalent polar lipid-peptide conjugates for immunological targeting
AU668873B2 (en) 1991-07-12 1996-05-23 Chimerix, Inc. Antiviral liponucleosides: treatment of hepatitis B
JPH07188280A (ja) * 1993-12-28 1995-07-25 L T T Kenkyusho:Kk ホスファチジルエタノールアミン類結合生理活性物質およびその中間体
US5534499A (en) * 1994-05-19 1996-07-09 The University Of British Columbia Lipophilic drug derivatives for use in liposomes
EP0805684B1 (en) 1995-01-27 2002-06-12 The Board Of Regents, The University Of Texas System Methods of enhancing the therapeutic activity of nsaids and compositions of zwitterionic phospholipids useful therein
JP3781877B2 (ja) * 1997-10-03 2006-05-31 株式会社ムック アスコルビン酸誘導体またはその塩、および医薬
IL127143A0 (en) * 1998-11-19 1999-09-22 Dpharm Ltd Phospholipid terivatives of non-steroidal anti inflammatory drugs

Also Published As

Publication number Publication date
CA2346869C (en) 2010-03-23
US7417035B2 (en) 2008-08-26
CA2346869A1 (en) 2000-06-02
EP1131326A1 (en) 2001-09-12
JP2002530410A (ja) 2002-09-17
US20040147485A1 (en) 2004-07-29
AU1292800A (en) 2000-06-13
DE69907720D1 (de) 2003-06-12
EP1131326A4 (en) 2002-03-27
DE69907720T2 (de) 2004-02-26
US6730696B1 (en) 2004-05-04
EP1131326B1 (en) 2003-05-07
WO2000031083A1 (en) 2000-06-02
NZ510938A (en) 2002-11-26
ZA200102718B (en) 2001-10-05
AU766045B2 (en) 2003-10-09
ATE239739T1 (de) 2003-05-15
US7173018B2 (en) 2007-02-06
US20070191310A1 (en) 2007-08-16

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