CA2180624A1 - Diphenyl-1,2,3-thiadiazoles as anti-inflammatory agents - Google Patents

Diphenyl-1,2,3-thiadiazoles as anti-inflammatory agents

Info

Publication number
CA2180624A1
CA2180624A1 CA 2180624 CA2180624A CA2180624A1 CA 2180624 A1 CA2180624 A1 CA 2180624A1 CA 2180624 CA2180624 CA 2180624 CA 2180624 A CA2180624 A CA 2180624A CA 2180624 A1 CA2180624 A1 CA 2180624A1
Authority
CA
Canada
Prior art keywords
formula
thiadiazoles
diphenyl
inflammatory agents
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA 2180624
Other languages
French (fr)
Other versions
CA2180624C (en
Inventor
Cheuk Kun Lau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Canada Inc
Original Assignee
Merck Frosst Canada and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9603425.1A external-priority patent/GB9603425D0/en
Application filed by Merck Frosst Canada and Co filed Critical Merck Frosst Canada and Co
Publication of CA2180624A1 publication Critical patent/CA2180624A1/en
Application granted granted Critical
Publication of CA2180624C publication Critical patent/CA2180624C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Abstract

The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I.

(see formula I) The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.
CA 2180624 1995-07-12 1996-07-05 Diphenyl-1,2,3-thiadiazoles as anti-inflammatory agents Expired - Fee Related CA2180624C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US107195P 1995-07-12 1995-07-12
US60/001,071 1995-07-12
GB9603425.1 1996-02-19
GBGB9603425.1A GB9603425D0 (en) 1996-02-19 1996-02-19 Diphenyl-1 2 3-thiadiazoles as anti-inflammatory agents

Publications (2)

Publication Number Publication Date
CA2180624A1 true CA2180624A1 (en) 1997-01-13
CA2180624C CA2180624C (en) 2006-12-12

Family

ID=26308753

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2180624 Expired - Fee Related CA2180624C (en) 1995-07-12 1996-07-05 Diphenyl-1,2,3-thiadiazoles as anti-inflammatory agents

Country Status (1)

Country Link
CA (1) CA2180624C (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887893B1 (en) 1997-12-24 2005-05-03 Sankyo Company, Limited Methods and compositions for treatment and prevention of tumors, tumor-related disorders and cachexia
US7320996B2 (en) 2001-08-15 2008-01-22 Sugen, Inc Indolinone protein kinase inhibitors and cyclooxygenase inhibitors for use in combination therapy for the treatment of cancer
WO2022195579A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201000016A1 (en) 2007-07-12 2010-10-29 Трагара Фармасьютикалс, Инк. METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER, TUMORS AND DISTURBANCES ASSOCIATED WITH TUMORS

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887893B1 (en) 1997-12-24 2005-05-03 Sankyo Company, Limited Methods and compositions for treatment and prevention of tumors, tumor-related disorders and cachexia
US7745481B2 (en) 1997-12-24 2010-06-29 Daiichi Sankyo Company, Limited Methods and compositions for the treatment and prevention of tumors, tumor-related disorders and cachexia
US7320996B2 (en) 2001-08-15 2008-01-22 Sugen, Inc Indolinone protein kinase inhibitors and cyclooxygenase inhibitors for use in combination therapy for the treatment of cancer
WO2022195579A1 (en) 2021-03-15 2022-09-22 Saul Yedgar Hyaluronic acid-conjugated dipalmitoyl phosphatidyl ethanolamine in combination with non-steroidal anti-inflammatory drugs (nsaids) for treating or alleviating inflammatory diseases

Also Published As

Publication number Publication date
CA2180624C (en) 2006-12-12

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