IL124966A - 1-indanyl-and 1-indanylidene-acetic acid derivatives - Google Patents
1-indanyl-and 1-indanylidene-acetic acid derivativesInfo
- Publication number
- IL124966A IL124966A IL12496695A IL12496695A IL124966A IL 124966 A IL124966 A IL 124966A IL 12496695 A IL12496695 A IL 12496695A IL 12496695 A IL12496695 A IL 12496695A IL 124966 A IL124966 A IL 124966A
- Authority
- IL
- Israel
- Prior art keywords
- pct
- indanylidene
- indanyl
- acetic acid
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C17/00—Preparation of halogenated hydrocarbons
- C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
- C07C17/10—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
- C07C17/14—Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
- C07C57/60—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/64—Acyl halides
- C07C57/76—Acyl halides containing halogen outside the carbonyl halide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/62—Halogen-containing esters
- C07C69/65—Halogen-containing esters of unsaturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pain & Pain Management (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP94303350 | 1994-05-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
IL124966A true IL124966A (en) | 1999-12-22 |
Family
ID=8217701
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12496695A IL124966A (en) | 1994-05-10 | 1995-05-09 | 1-indanyl-and 1-indanylidene-acetic acid derivatives |
IL11366595A IL113665A (en) | 1994-05-10 | 1995-05-09 | Amide derivatives their preparation pharmaceutical compositions containing them and their use |
IL12496698A IL124966A0 (en) | 1994-05-10 | 1998-06-17 | 1-indanyl- and 1-indanylidene-acetic derivatives |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11366595A IL113665A (en) | 1994-05-10 | 1995-05-09 | Amide derivatives their preparation pharmaceutical compositions containing them and their use |
IL12496698A IL124966A0 (en) | 1994-05-10 | 1998-06-17 | 1-indanyl- and 1-indanylidene-acetic derivatives |
Country Status (26)
Country | Link |
---|---|
US (1) | US5708033A (sl) |
EP (1) | EP0759026B1 (sl) |
JP (1) | JP3419462B2 (sl) |
KR (1) | KR100361788B1 (sl) |
CN (1) | CN1079788C (sl) |
AT (1) | ATE183496T1 (sl) |
AU (1) | AU702606B2 (sl) |
BR (1) | BR9507677A (sl) |
CA (1) | CA2190009A1 (sl) |
DE (1) | DE69511544T2 (sl) |
DK (1) | DK0759026T3 (sl) |
ES (1) | ES2134472T3 (sl) |
FI (1) | FI964482A (sl) |
GR (1) | GR3031458T3 (sl) |
HK (1) | HK1014532A1 (sl) |
HU (1) | HU219241B (sl) |
IL (3) | IL124966A (sl) |
MX (1) | MX9605458A (sl) |
MY (1) | MY113062A (sl) |
NO (1) | NO308654B1 (sl) |
NZ (1) | NZ285134A (sl) |
RU (1) | RU2145954C1 (sl) |
SI (1) | SI0759026T1 (sl) |
TW (1) | TW340109B (sl) |
WO (1) | WO1995030645A1 (sl) |
ZA (1) | ZA953753B (sl) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6391282B1 (en) * | 1997-11-10 | 2002-05-21 | Flemington Pharmaceutical Corp. | Antihistamine sprays and ointments for relief of delayed contact dermatitis |
DE19837069C1 (de) * | 1998-08-17 | 2000-01-05 | Bayer Ag | Substituierte Zimtsäuren und Zimtsäureester, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von substituierten Indanoncarbonsäureestern |
JP2004532188A (ja) * | 2001-02-06 | 2004-10-21 | グラクソ グループ リミテッド | 増強したカリウムチャネル活性に応答する疾患の治療のための二環式エステルまたはアミドの使用 |
US6956129B2 (en) * | 2001-02-16 | 2005-10-18 | Bayer Aktiengesellschaft | Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives |
ES2262567T3 (es) * | 2001-03-20 | 2006-12-01 | Schwarz Pharma Ag | Nuevo uso de una clase peptidica de compuesto para tratamiento del dolor inflamatorio no neuropatico. |
ES2185606T3 (es) | 2001-03-21 | 2003-05-01 | Sanol Arznei Schwarz Gmbh | Nuevo uso de una clase de compuestos peptidicos para tratamiento de la alodinia u otros tipos diferentes de dolor cronico o fantasma. |
US20040048874A1 (en) * | 2001-05-22 | 2004-03-11 | Bardsley Hazel Judith | New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine |
GB0216027D0 (en) * | 2002-07-10 | 2002-08-21 | Arachnova Therapeutics Ltd | New therapeutic use |
JP2006516976A (ja) * | 2003-01-13 | 2006-07-13 | ダイノゲン ファーマシューティカルズ,インコーポレイテッド | 機能性腸障害を処置する方法 |
JP2007532607A (ja) | 2004-04-16 | 2007-11-15 | シュバルツ ファルマ アクチェンゲゼルシャフト | 慢性頭痛の予防及び治療のためのペプチド化合物の使用 |
MX2007002269A (es) | 2004-08-27 | 2007-06-15 | Sanol Arznei Schwarz Gmbh | Uso novedoso de compuestos peptidos para tratar dolor por c??ncer de huesos, dolor inducido por quimioterapia y nucleosidos. |
WO2007076306A1 (en) * | 2005-12-20 | 2007-07-05 | Nps Pharmaceuticals, Inc. | Fluorinated compounds |
EP2695618B2 (en) | 2006-06-15 | 2022-05-11 | UCB Pharma GmbH | Pharmaceutical composition comprising lacosamide and levetiracetam for use in the treatment of epilepsy |
RU2522460C1 (ru) * | 2013-01-09 | 2014-07-10 | Федеральное государственное бюджетное учреждение высшего профессионального образования "Кемеровский государственный университет" (КемГУ) | Способ получения алкенилантрахинонов |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE371190B (sl) * | 1972-03-24 | 1974-11-11 | Kabi Ab | |
US3325358A (en) * | 1962-06-06 | 1967-06-13 | Merck & Co Inc | Method of treating inflammation |
NO136750C (no) * | 1972-06-19 | 1977-11-02 | Takeda Chemical Industries Ltd | Fremgangsm}te for fremstilling av indanderivater |
JPS5623982B2 (sl) * | 1972-12-07 | 1981-06-03 | ||
US5416118A (en) * | 1992-04-09 | 1995-05-16 | Schering Corporation | Bicyclic amides as inhibitors of acyl-coenzyme A: cholesterol acyl transferase |
GB9309621D0 (en) * | 1993-05-11 | 1993-06-23 | Wellcome Found | Amide derivatives and their therapeutic use |
-
1995
- 1995-05-08 MY MYPI95001216A patent/MY113062A/en unknown
- 1995-05-09 IL IL12496695A patent/IL124966A/xx not_active IP Right Cessation
- 1995-05-09 BR BR9507677A patent/BR9507677A/pt not_active Application Discontinuation
- 1995-05-09 RU RU96123227/04A patent/RU2145954C1/ru not_active IP Right Cessation
- 1995-05-09 HU HU9603103A patent/HU219241B/hu not_active IP Right Cessation
- 1995-05-09 JP JP52878795A patent/JP3419462B2/ja not_active Expired - Fee Related
- 1995-05-09 AU AU24138/95A patent/AU702606B2/en not_active Ceased
- 1995-05-09 NZ NZ285134A patent/NZ285134A/en unknown
- 1995-05-09 CA CA002190009A patent/CA2190009A1/en not_active Abandoned
- 1995-05-09 ES ES95918068T patent/ES2134472T3/es not_active Expired - Lifetime
- 1995-05-09 IL IL11366595A patent/IL113665A/xx not_active IP Right Cessation
- 1995-05-09 KR KR1019960706354A patent/KR100361788B1/ko not_active IP Right Cessation
- 1995-05-09 MX MX9605458A patent/MX9605458A/es not_active IP Right Cessation
- 1995-05-09 EP EP95918068A patent/EP0759026B1/en not_active Expired - Lifetime
- 1995-05-09 DK DK95918068T patent/DK0759026T3/da active
- 1995-05-09 WO PCT/GB1995/001040 patent/WO1995030645A1/en active IP Right Grant
- 1995-05-09 US US08/732,476 patent/US5708033A/en not_active Expired - Fee Related
- 1995-05-09 AT AT95918068T patent/ATE183496T1/de not_active IP Right Cessation
- 1995-05-09 ZA ZA953753A patent/ZA953753B/xx unknown
- 1995-05-09 DE DE69511544T patent/DE69511544T2/de not_active Expired - Fee Related
- 1995-05-09 SI SI9530296T patent/SI0759026T1/sl not_active IP Right Cessation
- 1995-05-09 CN CN95193920A patent/CN1079788C/zh not_active Expired - Fee Related
- 1995-05-11 TW TW084104673A patent/TW340109B/zh active
-
1996
- 1996-11-07 FI FI964482A patent/FI964482A/fi not_active IP Right Cessation
- 1996-11-08 NO NO964750A patent/NO308654B1/no unknown
-
1998
- 1998-06-17 IL IL12496698A patent/IL124966A0/xx unknown
-
1999
- 1999-02-04 HK HK98115769A patent/HK1014532A1/xx not_active IP Right Cessation
- 1999-10-07 GR GR990402549T patent/GR3031458T3/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |