IL123884A - 6-formylpterin derivatives and oligomers and polymers thereof, for use as active oxygen scavengers - Google Patents
6-formylpterin derivatives and oligomers and polymers thereof, for use as active oxygen scavengersInfo
- Publication number
- IL123884A IL123884A IL12388497A IL12388497A IL123884A IL 123884 A IL123884 A IL 123884A IL 12388497 A IL12388497 A IL 12388497A IL 12388497 A IL12388497 A IL 12388497A IL 123884 A IL123884 A IL 123884A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- formula
- active oxygen
- derivative
- hydrogen atom
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/522—Antioxidants; Radical scavengers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21804396 | 1996-07-31 | ||
PCT/JP1997/002649 WO1998004558A1 (fr) | 1996-07-31 | 1997-07-30 | Piegeurs d'oxygene actifs a base de derives de pterine |
Publications (2)
Publication Number | Publication Date |
---|---|
IL123884A0 IL123884A0 (en) | 1998-10-30 |
IL123884A true IL123884A (en) | 2002-04-21 |
Family
ID=16713759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL12388497A IL123884A (en) | 1996-07-31 | 1997-07-30 | 6-formylpterin derivatives and oligomers and polymers thereof, for use as active oxygen scavengers |
Country Status (10)
Country | Link |
---|---|
US (1) | US6162806A (fr) |
EP (1) | EP0884317B1 (fr) |
KR (1) | KR19990063880A (fr) |
CN (1) | CN1084332C (fr) |
AT (1) | ATE295847T1 (fr) |
AU (1) | AU739069B2 (fr) |
DE (1) | DE69733308D1 (fr) |
IL (1) | IL123884A (fr) |
NZ (1) | NZ330078A (fr) |
WO (1) | WO1998004558A1 (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69920757T2 (de) * | 1998-12-28 | 2005-12-15 | 4 AZA Bioscience N.V. | Immunosuppressive wirkungen von pteridinderivaten |
US7276506B2 (en) | 1998-12-28 | 2007-10-02 | 4 Aza Bioscience Nv | Immunosuppressive effects of pteridine derivatives |
CA2545584C (fr) | 2003-11-17 | 2012-10-23 | Biomarin Pharmaceutical Inc. | Methodes et compositions destinees au traitement de troubles metaboliques |
MX2007005039A (es) | 2004-11-17 | 2007-06-19 | Biomarin Pharm Inc | Formulacion de tableta estable. |
US9259426B2 (en) | 2006-07-20 | 2016-02-16 | Gilead Sciences, Inc. | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections |
US10144736B2 (en) | 2006-07-20 | 2018-12-04 | Gilead Sciences, Inc. | Substituted pteridines useful for the treatment and prevention of viral infections |
JP2010515747A (ja) * | 2007-01-12 | 2010-05-13 | ビオマリン プハルマセウトイカル インコーポレイテッド | テトラヒドロビオプテリンプロドラッグ |
KR100882340B1 (ko) * | 2007-03-30 | 2009-02-11 | 주식회사 래디안 | 테리딘이 유효성분으로 포함된 나노리포좀 함유 화장료 조성물 및 그 제조방법 |
BRPI0821970A2 (pt) * | 2008-01-03 | 2015-06-23 | Biomarin Pharm Inc | Análogos de pterina para tratamento de condição responsiva a bh4 |
WO2011159471A2 (fr) * | 2010-06-18 | 2011-12-22 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibiteurs de hppk de purine-ptérine liée utile en tant qu'agents antibactériens |
US9216178B2 (en) | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
US10316167B2 (en) * | 2014-09-19 | 2019-06-11 | Plastipak Packaging | Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions |
SI3321265T1 (sl) | 2015-03-04 | 2020-07-31 | Gilead Sciences, Inc. | Spojine 4,6-diamino-pirido(3,2-d)pirimidina in njihova uporaba kot modulatorji toličnih receptorjev |
MA46093A (fr) | 2016-09-02 | 2021-05-19 | Gilead Sciences Inc | Composés modulateurs du recepteur de type toll |
US10640499B2 (en) | 2016-09-02 | 2020-05-05 | Gilead Sciences, Inc. | Toll like receptor modulator compounds |
WO2018071531A1 (fr) | 2016-10-11 | 2018-04-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Inhibiteurs de hppk utiles en tant qu'agents antibactériens |
TWI751516B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
TW202212339A (zh) | 2019-04-17 | 2022-04-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
TW202115056A (zh) | 2019-06-28 | 2021-04-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑化合物的製備方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4994303A (en) * | 1988-03-21 | 1991-02-19 | Garlock, Inc. | Fiber impregnation process |
JPH0656669A (ja) * | 1992-06-11 | 1994-03-01 | Asahi Breweries Ltd | 活性酸素消去作用を持つプテリン誘導体製剤 |
DE4418096A1 (de) * | 1994-05-24 | 1995-11-30 | Cassella Ag | Verwendung von Pteridin-Derivaten als Hemmstoffe der NO-Synthase |
ATE218345T1 (de) * | 1994-08-05 | 2002-06-15 | Suntory Ltd | Arzneimittel gegen spinocerebellare degeneration |
KR20060094988A (ko) * | 1996-08-30 | 2006-08-30 | 다이이치 아스비오파마 가부시키가이샤 | 질소 산화물 합성효소 (nos)의 기능 저하에 의해유발되는 질환의 예방 또는 치료제 |
-
1997
- 1997-07-30 EP EP97933848A patent/EP0884317B1/fr not_active Expired - Lifetime
- 1997-07-30 WO PCT/JP1997/002649 patent/WO1998004558A1/fr active IP Right Grant
- 1997-07-30 KR KR1019980702352A patent/KR19990063880A/ko not_active Application Discontinuation
- 1997-07-30 AU AU37071/97A patent/AU739069B2/en not_active Ceased
- 1997-07-30 US US09/051,054 patent/US6162806A/en not_active Expired - Fee Related
- 1997-07-30 DE DE69733308T patent/DE69733308D1/de not_active Expired - Lifetime
- 1997-07-30 IL IL12388497A patent/IL123884A/en not_active IP Right Cessation
- 1997-07-30 NZ NZ330078A patent/NZ330078A/xx unknown
- 1997-07-30 AT AT97933848T patent/ATE295847T1/de not_active IP Right Cessation
- 1997-07-30 CN CN97191002A patent/CN1084332C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1084332C (zh) | 2002-05-08 |
DE69733308D1 (de) | 2005-06-23 |
US6162806A (en) | 2000-12-19 |
CN1198161A (zh) | 1998-11-04 |
IL123884A0 (en) | 1998-10-30 |
AU3707197A (en) | 1998-02-20 |
AU739069B2 (en) | 2001-10-04 |
EP0884317B1 (fr) | 2005-05-18 |
NZ330078A (en) | 2000-01-28 |
WO1998004558A1 (fr) | 1998-02-05 |
EP0884317A2 (fr) | 1998-12-16 |
EP0884317A4 (fr) | 1999-04-14 |
KR19990063880A (ko) | 1999-07-26 |
ATE295847T1 (de) | 2005-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |