IL123656A - History of isoxazolidine, process for preparation and pharmaceutical preparations containing these histories - Google Patents
History of isoxazolidine, process for preparation and pharmaceutical preparations containing these historiesInfo
- Publication number
- IL123656A IL123656A IL12365697A IL12365697A IL123656A IL 123656 A IL123656 A IL 123656A IL 12365697 A IL12365697 A IL 12365697A IL 12365697 A IL12365697 A IL 12365697A IL 123656 A IL123656 A IL 123656A
- Authority
- IL
- Israel
- Prior art keywords
- formula
- alkyl
- independently
- hydrogen
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/30—Phthalazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Photoreceptors In Electrophotography (AREA)
- Developing Agents For Electrophotography (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP96200991 | 1996-04-12 | ||
| PCT/EP1997/001830 WO1997039001A1 (en) | 1996-04-12 | 1997-04-09 | Isoxazolidine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL123656A0 IL123656A0 (en) | 1998-10-30 |
| IL123656A true IL123656A (en) | 2001-09-13 |
Family
ID=8223869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL12365697A IL123656A (en) | 1996-04-12 | 1997-04-09 | History of isoxazolidine, process for preparation and pharmaceutical preparations containing these histories |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6156747A (pl) |
| EP (1) | EP0892804B1 (pl) |
| JP (1) | JP4299884B2 (pl) |
| KR (1) | KR100598724B1 (pl) |
| CN (1) | CN1082963C (pl) |
| AT (1) | ATE222911T1 (pl) |
| AU (1) | AU716470B2 (pl) |
| DE (1) | DE69714980T2 (pl) |
| DK (1) | DK0892804T3 (pl) |
| ES (1) | ES2182064T3 (pl) |
| HU (1) | HU221608B (pl) |
| IL (1) | IL123656A (pl) |
| MY (1) | MY117456A (pl) |
| NO (1) | NO310077B1 (pl) |
| NZ (1) | NZ329954A (pl) |
| PL (1) | PL186541B1 (pl) |
| PT (1) | PT892804E (pl) |
| TW (1) | TW514637B (pl) |
| WO (1) | WO1997039001A1 (pl) |
| ZA (1) | ZA973122B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO588297A0 (en) * | 1997-03-26 | 1997-04-24 | Luminis Pty Limited | Mediation in melatonin production |
| US20050148018A1 (en) | 1999-10-07 | 2005-07-07 | David Weiner | Methods of identifying inverse agonists of the serotonin 2A receptor |
| UA77650C2 (en) | 1999-12-06 | 2007-01-15 | Lundbeck & Co As H | Use of serotonin reuptake inhibitor in combination with deramcyclane |
| SI1368358T1 (sl) * | 2001-02-21 | 2007-02-28 | Janssen Pharmaceutica Nv | Izoksazolinski derivati kot antidepresivi |
| JP4937141B2 (ja) * | 2005-01-27 | 2012-05-23 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Ｃｎｓ障害の処置における５ｈｔ２インヒビターとしての複素環式四環式テトラヒドロフラン誘導体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7414038A (nl) * | 1974-10-28 | 1976-05-03 | Akzo Nv | Nieuwe tetracyclische pyrrolidino derivaten. |
| TW206227B (pl) * | 1989-10-05 | 1993-05-21 | Sankyo Co | |
| US5552399A (en) * | 1994-11-02 | 1996-09-03 | Janssen Pharmaceutica N.V. | Substituted tetracyclic azepine derivatives |
| DK0789702T3 (da) * | 1994-11-02 | 2001-06-11 | Janssen Pharmaceutica Nv | Substituerede tetracykliske oxazepin- og thiazepinderivater med 5HT2-receptoraffinitet |
-
1997
- 1997-04-09 DK DK97919344T patent/DK0892804T3/da active
- 1997-04-09 AT AT97919344T patent/ATE222911T1/de active
- 1997-04-09 US US09/155,839 patent/US6156747A/en not_active Expired - Lifetime
- 1997-04-09 PT PT97919344T patent/PT892804E/pt unknown
- 1997-04-09 KR KR1019980703537A patent/KR100598724B1/ko not_active Expired - Lifetime
- 1997-04-09 IL IL12365697A patent/IL123656A/en not_active IP Right Cessation
- 1997-04-09 JP JP53673497A patent/JP4299884B2/ja not_active Expired - Lifetime
- 1997-04-09 HU HU9901875A patent/HU221608B/hu unknown
- 1997-04-09 AU AU23852/97A patent/AU716470B2/en not_active Expired
- 1997-04-09 WO PCT/EP1997/001830 patent/WO1997039001A1/en not_active Ceased
- 1997-04-09 PL PL97326871A patent/PL186541B1/pl unknown
- 1997-04-09 NZ NZ329954A patent/NZ329954A/xx not_active IP Right Cessation
- 1997-04-09 EP EP97919344A patent/EP0892804B1/en not_active Expired - Lifetime
- 1997-04-09 DE DE69714980T patent/DE69714980T2/de not_active Expired - Lifetime
- 1997-04-09 ES ES97919344T patent/ES2182064T3/es not_active Expired - Lifetime
- 1997-04-09 CN CN97191421A patent/CN1082963C/zh not_active Expired - Lifetime
- 1997-04-10 TW TW086104562A patent/TW514637B/zh not_active IP Right Cessation
- 1997-04-11 ZA ZA973122A patent/ZA973122B/xx unknown
- 1997-04-11 MY MYPI97001599A patent/MY117456A/en unknown
-
1998
- 1998-03-11 NO NO981077A patent/NO310077B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100598724B1 (ko) | 2006-10-25 |
| HU221608B (hu) | 2002-11-28 |
| EP0892804B1 (en) | 2002-08-28 |
| DK0892804T3 (da) | 2002-12-02 |
| EP0892804A1 (en) | 1999-01-27 |
| JP4299884B2 (ja) | 2009-07-22 |
| DE69714980D1 (de) | 2002-10-02 |
| PL326871A1 (en) | 1998-10-26 |
| CN1205010A (zh) | 1999-01-13 |
| DE69714980T2 (de) | 2003-04-10 |
| NZ329954A (en) | 1999-07-29 |
| PT892804E (pt) | 2003-01-31 |
| AU716470B2 (en) | 2000-02-24 |
| ES2182064T3 (es) | 2003-03-01 |
| CN1082963C (zh) | 2002-04-17 |
| KR19990067515A (ko) | 1999-08-25 |
| WO1997039001A1 (en) | 1997-10-23 |
| ZA973122B (en) | 1998-10-12 |
| HUP9901875A2 (hu) | 1999-09-28 |
| HUP9901875A3 (en) | 2000-06-28 |
| NO981077D0 (no) | 1998-03-11 |
| AU2385297A (en) | 1997-11-07 |
| MY117456A (en) | 2004-06-30 |
| IL123656A0 (en) | 1998-10-30 |
| US6156747A (en) | 2000-12-05 |
| NO310077B1 (no) | 2001-05-14 |
| PL186541B1 (pl) | 2004-01-30 |
| NO981077L (no) | 1998-10-12 |
| ATE222911T1 (de) | 2002-09-15 |
| TW514637B (en) | 2002-12-21 |
| JP2000508328A (ja) | 2000-07-04 |
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| AU716470B2 (en) | Isoxazolidine derivatives | |
| AU704285B2 (en) | Substituted tetracyclic azepine derivatives which have affinity for 5-HT2 receptors | |
| US5773433A (en) | Substituted tetracyclic oxazepine and thiazepine derivatives | |
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| AU712154C (en) | Substituted tetracyclic tetrahydrofuran derivatives | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| EXP | Patent expired |