IL123424A - Transformed derivatives of the N-heterocyclic H12-divenzo [[1,3] d, g] dioxoxin, their preparation and pharmaceutical preparations containing - Google Patents

Transformed derivatives of the N-heterocyclic H12-divenzo [[1,3] d, g] dioxoxin, their preparation and pharmaceutical preparations containing

Info

Publication number
IL123424A
IL123424A IL12342496A IL12342496A IL123424A IL 123424 A IL123424 A IL 123424A IL 12342496 A IL12342496 A IL 12342496A IL 12342496 A IL12342496 A IL 12342496A IL 123424 A IL123424 A IL 123424A
Authority
IL
Israel
Prior art keywords
hydrogen
compound according
halogen
compound
formula
Prior art date
Application number
IL12342496A
Other languages
English (en)
Hebrew (he)
Other versions
IL123424A0 (en
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of IL123424A0 publication Critical patent/IL123424A0/xx
Publication of IL123424A publication Critical patent/IL123424A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/48Drugs for disorders of the endocrine system of the pancreatic hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL12342496A 1995-09-19 1996-09-12 Transformed derivatives of the N-heterocyclic H12-divenzo [[1,3] d, g] dioxoxin, their preparation and pharmaceutical preparations containing IL123424A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK104195 1995-09-19
DK104095 1995-09-19
PCT/DK1996/000382 WO1997011071A1 (en) 1995-09-19 1996-09-12 Novel heterocyclic compounds

Publications (2)

Publication Number Publication Date
IL123424A0 IL123424A0 (en) 1998-09-24
IL123424A true IL123424A (en) 2002-02-10

Family

ID=26065121

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12342496A IL123424A (en) 1995-09-19 1996-09-12 Transformed derivatives of the N-heterocyclic H12-divenzo [[1,3] d, g] dioxoxin, their preparation and pharmaceutical preparations containing

Country Status (22)

Country Link
US (6) US5753678A (pl)
EP (1) EP0851865B1 (pl)
JP (1) JP3499569B2 (pl)
KR (1) KR100437561B1 (pl)
CN (1) CN1090629C (pl)
AR (1) AR004513A1 (pl)
AT (1) ATE220674T1 (pl)
AU (1) AU700784B2 (pl)
BR (1) BR9610524A (pl)
CA (1) CA2231835A1 (pl)
CZ (1) CZ70998A3 (pl)
DE (1) DE69622415T2 (pl)
ES (1) ES2179206T3 (pl)
HU (1) HUP9900079A3 (pl)
IL (1) IL123424A (pl)
MX (1) MX9802126A (pl)
NO (1) NO981216D0 (pl)
PL (1) PL186708B1 (pl)
PT (1) PT851865E (pl)
RU (1) RU2178790C2 (pl)
TW (1) TW406078B (pl)
WO (1) WO1997011071A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5952352A (en) * 1995-04-07 1999-09-14 Novo Nordisk A/S Heterocyclic compounds
JP2001502307A (ja) * 1996-10-04 2001-02-20 ノボ ノルディスク アクティーゼルスカブ 1,4―ジ置換ピペラジン
US6040318A (en) * 1997-06-25 2000-03-21 Novo Nordisk A/S Tricycle substituted with azaheterocyclic carboxylic acids
TW200400816A (en) 2002-06-26 2004-01-16 Lilly Co Eli Tricyclic steroid hormone nuclear receptor modulators
AU2004233863B2 (en) * 2003-04-24 2010-06-17 Incyte Holdings Corporation Aza spiro alkane derivatives as inhibitors of metalloproteases
WO2007143600A2 (en) * 2006-06-05 2007-12-13 Incyte Corporation Sheddase inhibitors combined with cd30-binding immunotherapeutics for the treatment of cd30 positive diseases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU174126B (hu) * 1977-08-02 1979-11-28 Egyt Gyogyszervegyeszeti Gyar Sposob poluchenija novykh proizvodnykh dibenzo-kvadratnaja skobka-d,g-kvadratnaja skobka zakryta-kvadratnaja skobka-1,3,6-kvadratnaja skobka zakryta-dioksazocina
HU195491B (en) * 1985-12-20 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
HU201318B (en) * 1987-12-31 1990-10-28 Egyt Gyogyszervegyeszeti Gyar Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same
CN1074926A (zh) * 1992-01-29 1993-08-04 大连石油化工公司有机合成厂 混合原油破乳剂的制备方法

Also Published As

Publication number Publication date
CN1196729A (zh) 1998-10-21
IL123424A0 (en) 1998-09-24
AU700784B2 (en) 1999-01-14
AR004513A1 (es) 1998-12-16
EP0851865B1 (en) 2002-07-17
MX9802126A (es) 1998-05-31
HUP9900079A2 (hu) 1999-10-28
PT851865E (pt) 2002-11-29
DE69622415T2 (de) 2003-03-06
US5753678A (en) 1998-05-19
ES2179206T3 (es) 2003-01-16
RU2178790C2 (ru) 2002-01-27
US5972925A (en) 1999-10-26
US5912262A (en) 1999-06-15
NO981216L (no) 1998-03-18
US6017915A (en) 2000-01-25
NO981216D0 (no) 1998-03-18
CA2231835A1 (en) 1997-03-27
BR9610524A (pt) 1999-07-06
KR19990063593A (ko) 1999-07-26
EP0851865A1 (en) 1998-07-08
DE69622415D1 (de) 2002-08-22
WO1997011071A1 (en) 1997-03-27
US5917047A (en) 1999-06-29
ATE220674T1 (de) 2002-08-15
PL325637A1 (en) 1998-08-03
CZ70998A3 (cs) 1998-08-12
JP3499569B2 (ja) 2004-02-23
TW406078B (en) 2000-09-21
KR100437561B1 (ko) 2004-07-16
CN1090629C (zh) 2002-09-11
HUP9900079A3 (en) 2000-02-28
AU6923496A (en) 1997-04-09
PL186708B1 (pl) 2004-02-27
JPH11506470A (ja) 1999-06-08
US5916901A (en) 1999-06-29

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees