IL123187A0 - 1-[2-(2,3-dihydro-1H-inden-1-yl)ethyl]-4-(naphth-1-yl)piperazine derivatives their preparation and their application in their therapeutics - Google Patents

1-[2-(2,3-dihydro-1H-inden-1-yl)ethyl]-4-(naphth-1-yl)piperazine derivatives their preparation and their application in their therapeutics

Info

Publication number
IL123187A0
IL123187A0 IL12318796A IL12318796A IL123187A0 IL 123187 A0 IL123187 A0 IL 123187A0 IL 12318796 A IL12318796 A IL 12318796A IL 12318796 A IL12318796 A IL 12318796A IL 123187 A0 IL123187 A0 IL 123187A0
Authority
IL
Israel
Prior art keywords
naphth
inden
therapeutics
dihydro
ethyl
Prior art date
Application number
IL12318796A
Other languages
English (en)
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL123187A0 publication Critical patent/IL123187A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
IL12318796A 1995-08-09 1996-08-01 1-[2-(2,3-dihydro-1H-inden-1-yl)ethyl]-4-(naphth-1-yl)piperazine derivatives their preparation and their application in their therapeutics IL123187A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9509684A FR2737724B1 (fr) 1995-08-09 1995-08-09 Derives de 1-[2-(2,3-dihydro-1h-inden-1-yl)ethyl]-4- (naphtalen-1-yl) piperazine, leur preparation et leur application en therapeutique
PCT/FR1996/001216 WO1997006155A1 (fr) 1995-08-09 1996-08-01 Derives de 1-[2-(2,3-dihydro-1h-inden-1-yl)ethyl]-4-(naphtalen-1-yl)piperazine, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
IL123187A0 true IL123187A0 (en) 1998-09-24

Family

ID=9481836

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12318796A IL123187A0 (en) 1995-08-09 1996-08-01 1-[2-(2,3-dihydro-1H-inden-1-yl)ethyl]-4-(naphth-1-yl)piperazine derivatives their preparation and their application in their therapeutics

Country Status (20)

Country Link
US (1) US5929078A (hu)
EP (1) EP0843670A1 (hu)
JP (1) JP2000501699A (hu)
KR (1) KR19990035954A (hu)
CN (1) CN1199398A (hu)
AR (1) AR003222A1 (hu)
AU (1) AU707372B2 (hu)
BR (1) BR9609977A (hu)
CA (1) CA2228843A1 (hu)
CO (1) CO4750833A1 (hu)
CZ (1) CZ36898A3 (hu)
FR (1) FR2737724B1 (hu)
HU (1) HUP9802546A3 (hu)
IL (1) IL123187A0 (hu)
NO (1) NO980529L (hu)
NZ (1) NZ315363A (hu)
PL (1) PL324966A1 (hu)
SK (1) SK16798A3 (hu)
WO (1) WO1997006155A1 (hu)
ZA (1) ZA966772B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI242011B (en) 1997-03-31 2005-10-21 Eisai Co Ltd 1,4-substituted cyclic amine derivatives
US8106074B2 (en) * 2001-07-13 2012-01-31 Pierre Fabre Medicament Pyridin-2-yl-methylamine derivatives for treating opiate dependence

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE358300A (hu) * 1928-04-28
US2927924A (en) * 1958-04-03 1960-03-08 Lilly Co Eli Novel phenethyl-substituted piperazines
NL132357C (hu) * 1966-09-03
DE2037852C3 (de) * 1970-07-30 1980-06-26 Boehringer Sohn Ingelheim Neue Piperazinderivate und Verfahren zu ihrer Herstellung
DK0737189T3 (da) * 1993-12-28 2000-03-06 Upjohn Co Heterocycliske forbindelser til behandling af CNS-forstyrrelser og cardiovaskulære forstyrrelser
FR2716193B1 (fr) * 1994-02-16 1996-04-05 Synthelabo Dérivés de 1[2-(1h-inden-3-yl)ethyl]-4-(naphtalen-1-yl)piperazine, leur préparation et leur application en thérapeutique.

Also Published As

Publication number Publication date
BR9609977A (pt) 1999-01-12
US5929078A (en) 1999-07-27
EP0843670A1 (fr) 1998-05-27
PL324966A1 (en) 1998-06-22
ZA966772B (en) 1997-02-19
SK16798A3 (en) 1998-08-05
JP2000501699A (ja) 2000-02-15
CO4750833A1 (es) 1999-03-31
HUP9802546A3 (en) 1999-10-28
CN1199398A (zh) 1998-11-18
FR2737724B1 (fr) 1997-09-05
FR2737724A1 (fr) 1997-02-14
WO1997006155A1 (fr) 1997-02-20
AU6705396A (en) 1997-03-05
NO980529D0 (no) 1998-02-06
AR003222A1 (es) 1998-07-08
AU707372B2 (en) 1999-07-08
CZ36898A3 (cs) 1998-05-13
CA2228843A1 (en) 1997-02-20
NO980529L (no) 1998-04-14
KR19990035954A (ko) 1999-05-25
MX9801057A (es) 1998-05-31
NZ315363A (en) 1998-10-28
HUP9802546A2 (hu) 1999-02-01

Similar Documents

Publication Publication Date Title
PL327406A1 (en) 1-(1,2-disubstituted-piperidinyl)-4-substituted derivatives of piperazine
HUP9601328A3 (en) 4-(aryl-amino-methylene)-2,4-dihydro-pyrazol-3-one derivatives and pharmaceutical compositions containing them
PL314135A1 (en) Heteroaryl piperidines, pyrolydines and piperazines and their application as antipsychotic and analgetic agents
HRP960503B1 (en) (-) cis-6(s)-phenyl-5(r)/4-(2-pyrrolidin-1-ylethoxy)-5,6,7,8-tetrahydronaphthalen-2-ol d-tartarate
NZ325845A (en) 1-(1,2-disubstituted piperidinyl)-4-(fused imidazole)-piperidine derivatives, preparation and pharmaceutical use thereof
NO2005009I1 (no) Emselex-Darifenacin-IUPAC-nabn: (S)-2-(1-Ä2-(2,3-dihydrobenzofuran-5-yl)etylÜ3-pyrrolidinylÜ-2,2-difenylacetamid
HU9802129D0 (en) New piperazine and piperidine derivatives
AU6524996A (en) Piperazine derivatives and their use as 5-HT1A antagonists
EP0796096A4 (en) 4,4- (DISUBSTITUTED) CYCLOHEXAN-1-CARBOXYLATE MONOMERS AND RELATED COMPOUNDS
ZA918293B (en) 1-(3,4-dihydro-2-oxo-1h-quinolin-6-yl)-2(4-(2-phenylethyl)piperidin-1-yl)ethanol and-ethanone,their preparation and their therapeutic application
IL112661A0 (en) 1-[2-(1h-inden-3-yl) ethyl]-4-(naphth-1-yl) piperazine derivatives, their preparation and their application in therapeutics
IL123187A0 (en) 1-[2-(2,3-dihydro-1H-inden-1-yl)ethyl]-4-(naphth-1-yl)piperazine derivatives their preparation and their application in their therapeutics
GB2297749B (en) 1-[2-(substituted vinyl)]-3-4--dihydro-5h-2,3-benzodiazepine derivatives
IL136231A (en) Process and intermediate for preparing cis-1-(2-[4-(6-methoxy-2-phenyl-1,2,3,4-tetrahydronaphthalen-1-yl)- phenoxy] ethyl) pyrrolidine
IL110963A0 (en) 1[2-amino-5-[1-(triphenylethyl)-1h-imadazol-4-yl]-1- oxopentyl] piperidine derivatives, their preparation and their use as synthetic intermediates
GB2286392B (en) Piperazine derivatives and pharmaceutical uses thereof
FR2722099B1 (fr) Nouveau produit de combinaison comprenant de la carpipramine et un neuroleptique.
Harvey Postmodernism and Democratic Theory
CS10790A2 (en) 2-(4-(2-chlorodibenzo/b,f/thiepin-10-yloxy/ethyl-1-piperazinyl)ethanol and its maleate
ATE194334T1 (de) 3-phenyl-1,4-dialkyl-1,2,4-triazolium salze und ihre verwendung als antidepressiva
ITRM940442A0 (it) Cerniera cilindrica d'angolo per serramenti in alluminio
GB2297750B (en) 1-[2-(Substituted vinyl)]-5h-2,3-benzodiazepine derivatives
ITBO940043V0 (it) Cavallotto di collegamento a "t" di profilati, in particolare di pro- filati metallici.
ITFI940047A0 (it) Procedimento per la fabbricazione di supporti cartacei per carta-moneta, carte-valori ed altro, e supporti cosi' realizzati
HUP9701007A3 (en) Process for producing 1-[2-(2,4-difluoro-phenyl)-2,3-epoxi-propyl]-1h-1,2,4-triazol and its salts