AR003222A1 - Derivados de 1-[2-(2,3-dihidro-1h-inden-1-il)etil]-4-(naftalen-1-il)- piperazina, procedimiento para prepararlos y medicamentos y composicionesfarmaceuticas que contienen dichos derivados. - Google Patents

Derivados de 1-[2-(2,3-dihidro-1h-inden-1-il)etil]-4-(naftalen-1-il)- piperazina, procedimiento para prepararlos y medicamentos y composicionesfarmaceuticas que contienen dichos derivados.

Info

Publication number
AR003222A1
AR003222A1 ARP960103928A AR10392896A AR003222A1 AR 003222 A1 AR003222 A1 AR 003222A1 AR P960103928 A ARP960103928 A AR P960103928A AR 10392896 A AR10392896 A AR 10392896A AR 003222 A1 AR003222 A1 AR 003222A1
Authority
AR
Argentina
Prior art keywords
derivatives
inden
piperazine
procedure
pharmaceutical compositions
Prior art date
Application number
ARP960103928A
Other languages
English (en)
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of AR003222A1 publication Critical patent/AR003222A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

Derivados de 1-[2-(2,3-dihidro-1H-inden-1-il)etil]-4-(naftalen-1-il) piperazina, de aplicación en terapéutica y un procedimiento para su preparaciónque responden a la fórmula (I), en la cual X representa un átomo de hidrógeno, un grupo hidroxi, un grupo alcoxi de 1 a 3 átomos de carbono o un grupociclopropilmetoxi, e Y representa un átomo de hidrógeno, un grupo hidroxi o un grupo metoxi. También se propone la preparación de dichos derivados ycomposiciones farmacéuticas y medicamentos que incluyen dichos derivados.
ARP960103928A 1995-08-09 1996-08-08 Derivados de 1-[2-(2,3-dihidro-1h-inden-1-il)etil]-4-(naftalen-1-il)- piperazina, procedimiento para prepararlos y medicamentos y composicionesfarmaceuticas que contienen dichos derivados. AR003222A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9509684A FR2737724B1 (fr) 1995-08-09 1995-08-09 Derives de 1-[2-(2,3-dihydro-1h-inden-1-yl)ethyl]-4- (naphtalen-1-yl) piperazine, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
AR003222A1 true AR003222A1 (es) 1998-07-08

Family

ID=9481836

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP960103928A AR003222A1 (es) 1995-08-09 1996-08-08 Derivados de 1-[2-(2,3-dihidro-1h-inden-1-il)etil]-4-(naftalen-1-il)- piperazina, procedimiento para prepararlos y medicamentos y composicionesfarmaceuticas que contienen dichos derivados.

Country Status (20)

Country Link
US (1) US5929078A (es)
EP (1) EP0843670A1 (es)
JP (1) JP2000501699A (es)
KR (1) KR19990035954A (es)
CN (1) CN1199398A (es)
AR (1) AR003222A1 (es)
AU (1) AU707372B2 (es)
BR (1) BR9609977A (es)
CA (1) CA2228843A1 (es)
CO (1) CO4750833A1 (es)
CZ (1) CZ36898A3 (es)
FR (1) FR2737724B1 (es)
HU (1) HUP9802546A3 (es)
IL (1) IL123187A0 (es)
NO (1) NO980529L (es)
NZ (1) NZ315363A (es)
PL (1) PL324966A1 (es)
SK (1) SK16798A3 (es)
WO (1) WO1997006155A1 (es)
ZA (1) ZA966772B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI242011B (en) 1997-03-31 2005-10-21 Eisai Co Ltd 1,4-substituted cyclic amine derivatives
US8106074B2 (en) 2001-07-13 2012-01-31 Pierre Fabre Medicament Pyridin-2-yl-methylamine derivatives for treating opiate dependence

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE358300A (es) * 1928-04-28
US2927924A (en) * 1958-04-03 1960-03-08 Lilly Co Eli Novel phenethyl-substituted piperazines
NL132357C (es) * 1966-09-03
DE2037852C3 (de) * 1970-07-30 1980-06-26 Boehringer Sohn Ingelheim Neue Piperazinderivate und Verfahren zu ihrer Herstellung
AU684874B2 (en) * 1993-12-28 1998-01-08 Pharmacia & Upjohn Company Heterocyclic compounds for the treatment of cns and cardiovascular disorders
FR2716193B1 (fr) * 1994-02-16 1996-04-05 Synthelabo Dérivés de 1[2-(1h-inden-3-yl)ethyl]-4-(naphtalen-1-yl)piperazine, leur préparation et leur application en thérapeutique.

Also Published As

Publication number Publication date
HUP9802546A2 (hu) 1999-02-01
CO4750833A1 (es) 1999-03-31
MX9801057A (es) 1998-05-31
FR2737724B1 (fr) 1997-09-05
BR9609977A (pt) 1999-01-12
EP0843670A1 (fr) 1998-05-27
KR19990035954A (ko) 1999-05-25
NZ315363A (en) 1998-10-28
HUP9802546A3 (en) 1999-10-28
NO980529L (no) 1998-04-14
CZ36898A3 (cs) 1998-05-13
WO1997006155A1 (fr) 1997-02-20
ZA966772B (en) 1997-02-19
IL123187A0 (en) 1998-09-24
SK16798A3 (en) 1998-08-05
JP2000501699A (ja) 2000-02-15
AU6705396A (en) 1997-03-05
AU707372B2 (en) 1999-07-08
CA2228843A1 (en) 1997-02-20
PL324966A1 (en) 1998-06-22
FR2737724A1 (fr) 1997-02-14
NO980529D0 (no) 1998-02-06
CN1199398A (zh) 1998-11-18
US5929078A (en) 1999-07-27

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