IL121053A - Method for removing N-terminal methionine - Google Patents

Method for removing N-terminal methionine

Info

Publication number
IL121053A
IL121053A IL12105397A IL12105397A IL121053A IL 121053 A IL121053 A IL 121053A IL 12105397 A IL12105397 A IL 12105397A IL 12105397 A IL12105397 A IL 12105397A IL 121053 A IL121053 A IL 121053A
Authority
IL
Israel
Prior art keywords
terminal
methionine residue
terminal methionine
peptide
salt
Prior art date
Application number
IL12105397A
Other languages
English (en)
Other versions
IL121053A0 (en
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of IL121053A0 publication Critical patent/IL121053A0/xx
Publication of IL121053A publication Critical patent/IL121053A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/246—IL-2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Forging (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
IL12105397A 1996-06-14 1997-06-10 Method for removing N-terminal methionine IL121053A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15463496 1996-06-14

Publications (2)

Publication Number Publication Date
IL121053A0 IL121053A0 (en) 1997-11-20
IL121053A true IL121053A (en) 2000-12-06

Family

ID=15588495

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12105397A IL121053A (en) 1996-06-14 1997-06-10 Method for removing N-terminal methionine

Country Status (11)

Country Link
US (2) US6066470A (zh)
EP (1) EP0812856B1 (zh)
KR (1) KR100478747B1 (zh)
CN (1) CN1158303C (zh)
AT (1) ATE185146T1 (zh)
CA (1) CA2207723C (zh)
DE (1) DE69700561T2 (zh)
DK (1) DK0812856T3 (zh)
ES (1) ES2136458T3 (zh)
GR (1) GR3032139T3 (zh)
IL (1) IL121053A (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2768743B1 (fr) * 1997-09-23 2001-09-14 Bio Merieux Procede de lyse de micro-organisme
CN1322211A (zh) 1998-10-05 2001-11-14 武田药品工业株式会社 除去n－末端蛋氨酸的方法
EP1138772A4 (en) * 1998-12-11 2005-04-06 Takeda Chemical Industries Ltd PROCESS FOR THE PRODUCTION OF APELINE
WO2002046405A1 (fr) * 2000-12-07 2002-06-13 Takeda Chemical Industries, Ltd. Procede de production de rfrp
JPWO2002052027A1 (ja) * 2000-12-22 2004-04-30 日本曹達株式会社 微生物触媒を用いた物質生産方法
KR20050090430A (ko) * 2002-12-31 2005-09-13 알투스 파마슈티컬스 인코포레이티드 인간 성장 호르몬 결정 및 이것의 제조 방법
DE10353973B4 (de) * 2003-11-19 2006-08-17 Beru Ag Verfahren zum Herstellen eines keramischen Glühstiftes für eine keramische Glühkerze
EP1976551A4 (en) * 2005-12-23 2009-12-30 Altus Pharmaceuticals Inc COMPOSITIONS COMPRISING COMPLEX PROTEIN CRYSTALS BY POLYCATIONS AND PROCESSING METHOD THEREOF
CA2939778C (en) 2007-01-31 2019-01-29 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
BRPI0809366B8 (pt) 2007-03-28 2021-05-25 Harvard College polipeptídeo substancialmente alfa-helicoidal, método para fabricação do mesmo, aminoácido e composição farmacêutica
CN103282510A (zh) 2010-08-13 2013-09-04 爱勒让治疗公司 拟肽大环化合物
BR112014009418A2 (pt) 2011-10-18 2017-04-18 Aileron Therapeutics Inc macrociclos peptidomiméticos
US8987414B2 (en) 2012-02-15 2015-03-24 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
EP2822572B1 (en) 2012-02-15 2020-06-10 Aileron Therapeutics, Inc. Peptidomimetic macrocycles
CN104812384B (zh) 2012-11-01 2020-09-18 爱勒让治疗公司 二取代的氨基酸及其制备和使用方法
IN2013MU02726A (zh) * 2013-08-21 2015-06-26 Cadila Healthcare Ltd
CA2961258A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
SG11201707750YA (en) 2015-03-20 2017-10-30 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007380A1 (en) 1985-06-04 1986-12-18 Takeda Chemical Industries, Ltd. Process for preparing polypeptide
IT1219454B (it) * 1988-02-17 1990-05-18 Serono Cesare Ist Ricerca Metodo di rottura alla metionina di polipeptidi contenenti pontidisolfuro
JPH06316557A (ja) * 1993-03-06 1994-11-15 Fuji Kagaku Kogyo Kk アルキルチオ脂肪酸誘導体、製造法及びその肝臓疾患、腎臓疾患、膵臓疾患及び脳疾患用剤

Also Published As

Publication number Publication date
EP0812856A1 (en) 1997-12-17
US6066470A (en) 2000-05-23
DE69700561T2 (de) 2000-05-04
KR100478747B1 (ko) 2005-09-08
US6309859B1 (en) 2001-10-30
DK0812856T3 (da) 2000-01-03
ATE185146T1 (de) 1999-10-15
EP0812856B1 (en) 1999-09-29
CA2207723C (en) 2006-12-12
KR980002062A (ko) 1998-03-30
CN1178798A (zh) 1998-04-15
CA2207723A1 (en) 1997-12-14
ES2136458T3 (es) 1999-11-16
IL121053A0 (en) 1997-11-20
DE69700561D1 (de) 1999-11-04
GR3032139T3 (en) 2000-04-27
CN1158303C (zh) 2004-07-21

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Legal Events

Date Code Title Description
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KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees