GR3032139T3 - Method for removing N-terminal methionine - Google Patents

Method for removing N-terminal methionine

Info

Publication number
GR3032139T3
GR3032139T3 GR990403225T GR990403225T GR3032139T3 GR 3032139 T3 GR3032139 T3 GR 3032139T3 GR 990403225 T GR990403225 T GR 990403225T GR 990403225 T GR990403225 T GR 990403225T GR 3032139 T3 GR3032139 T3 GR 3032139T3
Authority
GR
Greece
Prior art keywords
terminal
methionine residue
terminal methionine
peptide
salt
Prior art date
Application number
GR990403225T
Other languages
English (en)
Inventor
Osamu Nishimura
Masato Suenaga
Mae Hiroaki Oh
Shinji Tsuji
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of GR3032139T3 publication Critical patent/GR3032139T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/635—Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/246—IL-2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Forging (AREA)
GR990403225T 1996-06-14 1999-12-15 Method for removing N-terminal methionine GR3032139T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15463496 1996-06-14

Publications (1)

Publication Number Publication Date
GR3032139T3 true GR3032139T3 (en) 2000-04-27

Family

ID=15588495

Family Applications (1)

Application Number Title Priority Date Filing Date
GR990403225T GR3032139T3 (en) 1996-06-14 1999-12-15 Method for removing N-terminal methionine

Country Status (11)

Country Link
US (2) US6066470A (el)
EP (1) EP0812856B1 (el)
KR (1) KR100478747B1 (el)
CN (1) CN1158303C (el)
AT (1) ATE185146T1 (el)
CA (1) CA2207723C (el)
DE (1) DE69700561T2 (el)
DK (1) DK0812856T3 (el)
ES (1) ES2136458T3 (el)
GR (1) GR3032139T3 (el)
IL (1) IL121053A (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2768743B1 (fr) * 1997-09-23 2001-09-14 Bio Merieux Procede de lyse de micro-organisme
CN1322211A (zh) * 1998-10-05 2001-11-14 武田药品工业株式会社 除去n－末端蛋氨酸的方法
WO2000036122A1 (fr) * 1998-12-11 2000-06-22 Takeda Chemical Industries, Ltd. Procede de fabrication de l'apeline
CA2430701A1 (en) * 2000-12-07 2002-06-13 Takeda Chemical Industries, Ltd. Process for producing rfrp
WO2002052027A1 (fr) * 2000-12-22 2002-07-04 Nippon Soda Co., Ltd. Procede de production d'une substance a l'aide d'un catalyseur microbien
SG176314A1 (en) * 2002-12-31 2011-12-29 Altus Pharmaceuticals Inc Human growth hormone crystals and methods for preparing them
DE10353973B4 (de) * 2003-11-19 2006-08-17 Beru Ag Verfahren zum Herstellen eines keramischen Glühstiftes für eine keramische Glühkerze
EP1976551A4 (en) * 2005-12-23 2009-12-30 Altus Pharmaceuticals Inc COMPOSITIONS COMPRISING COMPLEX PROTEIN CRYSTALS BY POLYCATIONS AND PROCESSING METHOD THEREOF
CA2677045C (en) 2007-01-31 2016-10-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
ES2430067T3 (es) 2007-03-28 2013-11-18 President And Fellows Of Harvard College Polipéptidos cosidos
DK2603600T3 (da) 2010-08-13 2019-03-04 Aileron Therapeutics Inc Peptidomimetiske makrocyklusser
CA2852468A1 (en) 2011-10-18 2013-04-25 Aileron Therapeutics, Inc. Peptidomimetic macrocyles
CA2864120A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
NZ627528A (en) 2012-02-15 2016-05-27 Aileron Therapeutics Inc Peptidomimetic macrocycles
WO2014071241A1 (en) 2012-11-01 2014-05-08 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
KR101687686B1 (ko) * 2013-08-21 2016-12-19 카딜라 핼쓰캐어 리미티드 Pth를 정제하는 방법
WO2016049359A1 (en) 2014-09-24 2016-03-31 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
SG11201707750YA (en) 2015-03-20 2017-10-30 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986007380A1 (en) 1985-06-04 1986-12-18 Takeda Chemical Industries, Ltd. Process for preparing polypeptide
IT1219454B (it) * 1988-02-17 1990-05-18 Serono Cesare Ist Ricerca Metodo di rottura alla metionina di polipeptidi contenenti pontidisolfuro
JPH06316557A (ja) * 1993-03-06 1994-11-15 Fuji Kagaku Kogyo Kk アルキルチオ脂肪酸誘導体、製造法及びその肝臓疾患、腎臓疾患、膵臓疾患及び脳疾患用剤

Also Published As

Publication number Publication date
CA2207723C (en) 2006-12-12
CN1158303C (zh) 2004-07-21
DE69700561D1 (de) 1999-11-04
US6066470A (en) 2000-05-23
DE69700561T2 (de) 2000-05-04
EP0812856A1 (en) 1997-12-17
EP0812856B1 (en) 1999-09-29
IL121053A (en) 2000-12-06
KR980002062A (ko) 1998-03-30
IL121053A0 (en) 1997-11-20
CA2207723A1 (en) 1997-12-14
DK0812856T3 (da) 2000-01-03
KR100478747B1 (ko) 2005-09-08
ES2136458T3 (es) 1999-11-16
ATE185146T1 (de) 1999-10-15
CN1178798A (zh) 1998-04-15
US6309859B1 (en) 2001-10-30

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